1 |
POLR2E | parental protein | 103 | 0.155 | 4501.446 | RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain |
2 |
ARRB1 | interactor | 11 | 0.491 | 10.024 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
3 |
ARRB2 | interactor | 16 | 0.358 | 32.247 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
4 |
BARD1 | suppressor | 13 | 0.576 | 9.951 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
5 |
BRCA1 | suppressor | 26 | 0.443 | 63.723 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
6 |
CCDC8 | interactor | 17 | 0.483 | 24.506 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
7 |
CDH1 | suppressor | 7 | 0.467 | 2.669 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
8 |
COPS5 | protein found in more fusions | 15 | 0.440 | 18.318 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
9 |
CUL3 | protein found in more fusions | 29 | 0.294 | 134.694 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
10 |
CUL7 | protein found in more fusions | 18 | 0.493 | 20.170 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
11 |
EEF1A1 | suppressor | 23 | 0.394 | 54.074 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
12 |
ESR1 | suppressor | 35 | 0.374 | 172.023 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
13 |
FKBP14 | interactor | 1 | 0 | 0 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
14 |
FOS | oncoprotein | 5 | 0.500 | 1.682 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
15 |
GTF2B | interactor | 10 | 0.867 | 1.509 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
16 |
GTF2F2 | interactor | 15 | 0.590 | 22.965 | TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit |
17 |
HSP90AA1 | oncoprotein | 20 | 0.339 | 52.131 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
18 |
HSP90B1 | suppressor | 9 | 0.389 | 7.828 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
19 |
HTATSF1 | interactor | 6 | 0.667 | 2.109 | BUD22 (PF09073, IPR015158): BUD22 Conotoxin (PF02950, IPR004214): Conotoxin Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
20 |
IKBKG | interactor | 15 | 0.352 | 28.225 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
21 |
INTS10 | interactor | 9 | 1.000 | 0 | NA |
22 |
INTS3 | interactor | 14 | 0.692 | 10.334 | SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1 Fn_bind (PF02986, IPR004237): Fibronectin binding repeat Ints3 (PF10189, IPR019333): Integrator complex subunit 3 |
23 |
INTS5 | interactor | 12 | 0.924 | 1.004 | INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus INTS5_C (PF14838, IPR029444): Integrator complex subunit 5 C-terminus |
24 |
INTS6 | suppressor | 15 | 0.676 | 12.293 | VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596) |
25 |
ITCH | interactor | 11 | 0.556 | 7.202 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
26 |
LAMB1 | interactor | 1 | 0 | 0 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family YscO (PF07321, IPR009929): Type III secretion protein YscO Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI) Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein Ntox1 (PF15500, IPR029137): Putative RNase-like toxin, toxin_1 |
27 |
LZTR1 | oncoprotein | 7 | 0.600 | 2.026 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Sigma70_r3 (PF04539, IPR007624): Sigma-70 region 3 Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
28 |
MDC1 | suppressor | 15 | 0.467 | 17.698 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
29 |
MED1 | interactor | 14 | 0.782 | 4.821 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
30 |
MED10 | interactor | 20 | 0.800 | 7.053 | Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex |
31 |
MED12 | oncoprotein | 11 | 0.655 | 5.100 | Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
32 |
MED19 | interactor | 20 | 0.801 | 6.516 | Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 |
33 |
MED26 | interactor | 22 | 0.675 | 26.051 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain |
34 |
MED28 | interactor | 18 | 0.735 | 16.928 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
35 |
MED29 | interactor | 20 | 0.784 | 8.045 | Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
36 |
MED9 | interactor | 16 | 0.858 | 3.048 | Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9 |
37 |
MYC | oncoprotein | 17 | 0.450 | 30.037 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
38 |
NEDD4 | suppressor | 13 | 0.470 | 12.402 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
39 |
NPHP1 | interactor | 7 | 0.733 | 2.650 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FAM176 (PF14851): FAM176 family Speriolin_N (PF15058, IPR029385): Speriolin N terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
40 |
NPM1 | suppressor | 21 | 0.400 | 50.705 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
41 |
OBSL1 | interactor | 18 | 0.493 | 18.453 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
42 |
OFD1 | protein found in more fusions | 9 | 0.643 | 4.209 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit GrpE (PF01025, IPR000740): GrpE NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372) LisH_2 (PF16045, IPR006594): LisH |
43 |
PAAF1 | interactor | 1 | 0 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
44 |
PIH1D1 | protein found in more fusions | 28 | 0.370 | 116.514 | PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17 |
45 |
PML | suppressor | 5 | 0.500 | 1.619 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
46 |
POLR1A | interactor | 25 | 0.363 | 90.211 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 |
47 |
POLR1B | interactor | 18 | 0.431 | 44.848 | RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7 |
48 |
POLR1C | interactor | 23 | 0.451 | 68.087 | RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain |
49 |
POLR1D | interactor | 14 | 0.769 | 5.337 | RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain |
50 |
POLR2A | protein found in more fusions | 56 | 0.298 | 469.354 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
51 |
POLR2B | interactor | 52 | 0.287 | 449.214 | RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7 |
52 |
POLR2C | interactor | 45 | 0.367 | 212.830 | RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain |
53 |
POLR2D | interactor | 33 | 0.462 | 109.903 | RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 Tfb4 (PF03850, IPR004600): Transcription factor Tfb4 |
54 |
POLR2F | protein found in more fusions | 39 | 0.393 | 196.415 | RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6 |
55 |
POLR2G | interactor | 38 | 0.468 | 100.297 | SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain |
56 |
POLR2H | interactor | 42 | 0.388 | 209.293 | RNA_pol_Rpb8 (PF03870, IPR005570, SM00658): RNA polymerase Rpb8 |
57 |
POLR2I | interactor | 28 | 0.558 | 45.578 | RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) CpXC (PF14353, IPR025682): CpXC protein |
58 |
POLR2J | interactor | 31 | 0.503 | 57.961 | RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain |
59 |
POLR2K | interactor | 21 | 0.674 | 16.011 | DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit |
60 |
POLR2L | interactor | 29 | 0.473 | 67.157 | RNA_pol_N (PF01194, IPR000268): RNA polymerases N / 8 kDa subunit |
61 |
POLR2M | interactor | 16 | 0.742 | 6.985 | GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2 |
62 |
POLR3A | interactor | 23 | 0.478 | 59.852 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 |
63 |
POLR3B | interactor | 18 | 0.621 | 20.676 | RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7 |
64 |
POLR3C | interactor | 14 | 0.813 | 4.118 | HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain NIT (PF08376, IPR013587): Nitrate and nitrite sensing RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82 HD_4 (PF13328, IPR003607): HD domain |
65 |
POLR3D | interactor | 15 | 0.714 | 10.124 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 |
66 |
POLR3E | interactor | 17 | 0.588 | 22.621 | Sin_N (PF04801, IPR006886): Sin-like protein conserved region DUF2382 (PF09557, IPR019060): Domain of unknown function (DUF2382) |
67 |
POLR3F | interactor | 12 | 0.833 | 3.005 | RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit |
68 |
POLR3H | interactor | 11 | 0.964 | 0.382 | RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 |
69 |
POLR3K | interactor | 10 | 0.933 | 0.675 | RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) zf-ribbon_3 (PF13248): zinc-ribbon domain zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger |
70 |
PPP1CA | suppressor | 23 | 0.399 | 68.572 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
71 |
PPP1R3A | interactor | 7 | 0.905 | 0.487 | CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21) |
72 |
PSMB9 | interactor | 16 | 0.924 | 0.894 | Proteasome (PF00227, IPR001353): Proteasome subunit |
73 |
RABEP2 | interactor | 2 | 1.000 | 0 | Rab5-bind (PF09311, IPR015390): Rabaptin-like protein Rabaptin (PF03528, IPR018514): Rabaptin |
74 |
RECQL5 | oncoprotein | 12 | 0.864 | 2.210 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5) SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding TAtT (PF16811, IPR031823): TRAP transporter T-component |
75 |
RNF2 | interactor | 17 | 0.342 | 40.267 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
76 |
RPA1 | suppressor | 22 | 0.443 | 41.016 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
77 |
RPA2 | oncoprotein | 16 | 0.475 | 18.632 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
78 |
RPA3 | interactor | 17 | 0.475 | 18.632 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
79 |
RPAP3 | interactor | 25 | 0.380 | 80.046 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3 Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
80 |
RPRD1B | interactor | 18 | 0.608 | 22.913 | CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1 CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3 CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour |
81 |
RPS5 | interactor | 13 | 0.551 | 11.768 | Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e |
82 |
RUVBL1 | oncoprotein | 25 | 0.351 | 85.035 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
83 |
RUVBL2 | oncoprotein | 31 | 0.359 | 131.824 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
84 |
SEC13 | interactor | 5 | 0.667 | 0.376 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
85 |
SMG1 | interactor | 7 | 0.533 | 2.633 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein XhlA (PF10779, IPR019715): Haemolysin XhlA PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1 |
86 |
SRC | oncoprotein | 23 | 0.489 | 56.688 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
87 |
SRPK1 | interactor | 8 | 0.536 | 5.094 | FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pkinase (PF00069, IPR000719): Protein kinase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
88 |
SUPT5H | interactor | 23 | 0.427 | 61.940 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912) |
89 |
SYT5 | interactor | 2 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain MLANA (PF14991, IPR029242): Protein melan-A |
90 |
TAF10 | interactor | 4 | 0.833 | 0.200 | TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit |
91 |
TAF15 | oncoprotein | 14 | 0.385 | 22.574 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
92 |
TCEB3 | suppressor | 16 | 0.808 | 4.664 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain |
93 |
TRIM28 | protein found in more fusions | 17 | 0.442 | 23.219 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
94 |
TRIM29 | protein found in more fusions | 7 | 0.600 | 1.604 | MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
95 |
TTI1 | interactor | 7 | 0.857 | 1.200 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal |
96 |
URI1 | protein found in more fusions | 18 | 0.478 | 28.279 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein Prefoldin (PF02996, IPR004127): Prefoldin subunit DUF3835 (PF12927, IPR024325): Domain of unknown function (DUF3835) SCAPER_N (PF16501, IPR032446): S phase cyclin A-associated protein in the endoplasmic reticulum |
97 |
USP11 | protein found in more fusions | 6 | 0.800 | 0.733 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
98 |
UXT | interactor | 9 | 0.833 | 2.219 | Prefoldin (PF02996, IPR004127): Prefoldin subunit |
99 |
WWOX | suppressor | 11 | 0.527 | 11.014 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
100 |
XPO1 | interactor | 28 | 0.320 | 122.996 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
101 |
XRCC5 | suppressor | 20 | 0.351 | 44.335 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like |
102 |
ZNRD1 | interactor | 4 | 1.000 | 0 | RecR (PF02132, IPR023628): RecR protein RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) |
103 |
ZSCAN1 | interactor | 4 | 1.000 | 0 | SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain Tautomerase_2 (PF14552, IPR004370): Tautomerase enzyme |