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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)251
The number (and %) of the onco-proteins71 (28.29 %)
The number (and %) of the tumor suppressors41 (16.33 %)
Total number of binary PPIs (saturation %)2628 (8.38 %)
The number (and %) of affected PPIs251 (9.55 %)
The number of possible different fusions47
PPI diameter2
PPI radius1
The average degree of PPI20.239
Assortativity coefficient-0.1738
The network average Clustering coefficient0.448
The number (and %) of a zero Clustering coefficients4 (1.59 %)
The number (and %) of a zero Betweenness Centrality16 (6.37 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: POLR2A All fusions
: BF514571; BF512093;
Proteins found in more fusions AFF1 (see 2 fusions); VDR (see 2 fusions); PRPF19 (see 2 fusions); U2AF2 (see 2 fusions); SETD2 (see 2 fusions); AFF1/KMT2A (see 130 fusions); GRB2 (see 1 fusions); VHL (see 1 fusions); WAC (see 3 fusions); EWSR1 (see 2 fusions); MLLT1/KMT2A (see 19 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); RPA1 (see 1 fusions); NEDD4 (see 1 fusions); SRSF2 (see 1 fusions); MED21 (see 1 fusions); PRMT5 (see 2 fusions); GTF2E2 (see 2 fusions); POLR2E (see 2 fusions); KMT2A (see 16 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); QKI (see 3 fusions); DDB1 (see 2 fusions); EGLN1 (see 1 fusions); EEF1A1 (see 1 fusions); CUL7 (see 2 fusions); CSNK2A1/ELAVL1 (see 1 fusions); SMARCB1 (see 12 fusions); IVNS1ABP (see 2 fusions); MYC (see 1 fusions); KAT2B (see 1 fusions); ACTB (see 3 fusions); NELFB (see 1 fusions); RXRA (see 2 fusions); MYO6 (see 3 fusions); POLR2F/PIH1D1 (see 1 fusions); MCM7 (see 2 fusions); NFKB1 (see 2 fusions); CREB1 (see 2 fusions); CREBBP (see 6 fusions); MCM2 (see 1 fusions); MBD2 (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 POLR2Aparental protein2510.07434918.732RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
2 ACTBoncoprotein310.308132.738Actin (PF00022, IPR004000, SM00268): Actin
3 AFF1oncoprotein90.6435.690AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
4 AGO1interactor60.5331.699ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 AIREinteractor140.35912.106PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain; Sp100 domain
zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
6 ATF7IPoncoprotein60.6004.067TCP (PF03634, IPR005333): TCP family transcription factor
DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951)
ALMT (PF11744, IPR020966): Aluminium activated malate transporter
ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain
fn3_4 (PF16794, IPR003961): Fibronectin-III type domain
7 ATMsuppressor210.32648.407FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
8 ATP6V1B2interactor120.36416.923ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
9 BARD1suppressor320.241163.057BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
10 BRCA1suppressor660.193897.770BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
11 BRINP1suppressor21.0000MACPF (PF01823, IPR020864, SM00457): MAC/Perforin domain
12 CABIN1interactor31.0000FAT (PF02259, IPR003151): FAT domain
MEF2_binding (PF09047, IPR015134): MEF2 binding
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
13 CAND1interactor410.290219.436Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
14 CBX3interactor150.36318.958Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
15 CCDC8interactor310.326110.730Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
16 CCNHoncoprotein180.47129.6875_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
17 CCNKinteractor60.7330.925Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
18 CCNL2interactor30.6670.667Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
19 CCNT1oncoprotein170.39229.717Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
MDFI (PF15316, IPR026134): MyoD family inhibitor
20 CDC14Ainteractor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Pentaxin (PF00354, IPR001759, SM00159): Pentaxin family
PTPlike_phytase (PF14566): Inositol hexakisphosphate
DSPn (PF14671, IPR029260): Dual specificity protein phosphatase, N-terminal half
21 CDC73suppressor210.42455.437CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
22 CDK2suppressor410.294222.908Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
23 CDK7oncoprotein240.36069.194Pkinase (PF00069, IPR000719): Protein kinase domain
24 CDK8interactor320.409125.397Pkinase (PF00069, IPR000719): Protein kinase domain
25 CDK9protein found in more fusions320.245180.719Pkinase (PF00069, IPR000719): Protein kinase domain
26 CDKN1Asuppressor130.47419.203CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
27 CEP128interactor70.4295.465DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
28 CPSF1interactor200.32655.196CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
29 CPSF2interactor160.45029.640RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
30 CPSF3interactor150.42924.385Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF73-100_C (PF11718, IPR021718, SM01098): Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
31 CPSF3Linteractor80.8931.200RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
32 CREB1oncoprotein120.38220.127bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
33 CREBBPsuppressor340.294167.181Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
34 CSH2interactor100Hormone_1 (PF00103, IPR001400): Somatotropin hormone family
35 CSNK2A1oncoprotein420.237285.077Pkinase (PF00069, IPR000719): Protein kinase domain
36 CSTF1interactor70.6194.800WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
CSTF1_dimer (PF16699, IPR032028): Cleavage stimulation factor subunit 1, dimerisation domain
37 CSTF2interactor180.35340.763RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
38 CSTF3interactor130.41027.054NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
39 CTCFsuppressor80.3577.719cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
40 CTDP1interactor260.35189.417Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
FCP1_C (PF09309, IPR015388): FCP1, C-terminal
NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
41 CTDSP1interactor21.0000NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
42 CTDSP2interactor40.5003.000NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
43 CTR9interactor250.41361.679DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
Pap_E4 (PF02711, IPR003861): E4 protein
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
44 CUL2suppressor320.312119.355Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
45 CUL5suppressor380.283222.269Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
46 CUL7protein found in more fusions440.256229.320ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
47 DCTN2interactor110.33313.994Dynamitin (PF04912): Dynamitin
48 DCUN1D1interactor220.32568.901Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
49 DDB1protein found in more fusions300.273124.286CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
50 DDX5oncoprotein380.305158.698DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
51 DHX9oncoprotein400.332187.847DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
52 DNMT3Asuppressor110.5278.311DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
53 DNMT3Bsuppressor150.33334.435DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
54 EEDsuppressor410.153298.477WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
55 EEF1A1suppressor380.251223.758GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
56 EEF1A2oncoprotein110.4559.072GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
57 EEFSECinteractor50.4001.191RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
58 EGLN1suppressor40.6670.500zf-MYND (PF01753, IPR002893): MYND finger
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
59 EGLN2interactor31.00002OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
60 EHBP1L1interactor51.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
NT-C2 (PF10358, IPR019448): N-terminal C2 in EEIG1 and EHBP1 proteins
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
61 ELAVL1oncoprotein540.161633.339RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
62 ELP3interactor40.6671.154Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
Radical_SAM (PF04055, IPR007197): Radical SAM superfamily
Radical_SAM_C (PF16199, IPR032432): Radical_SAM C-terminal domain
63 EP300oncoprotein450.210397.995Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
64 ERCC1oncoprotein60.6004.452Rad10 (PF03834, IPR004579): Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
HHH_5 (PF14520): Helix-hairpin-helix domain
65 ERCC3oncoprotein170.33849.251ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
DUF2748 (PF10871, IPR020183): Protein of unknown function (DUF2748)
Helicase_C_3 (PF13625, IPR032830): Helicase conserved C-terminal domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
66 ERCC4oncoprotein70.4765.832ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
LUC7 (PF03194, IPR004882): LUC7 N_terminus
T2SSM_b (PF10741, IPR007690): Type II secretion system (T2SS), protein M subtype b
HHH_5 (PF14520): Helix-hairpin-helix domain
67 ERCC5oncoprotein90.47210.7385_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
IZUMO (PF15005, IPR029389): Izumo sperm-egg fusion, Ig domain-associated
Codanin-1_C (PF15296, IPR028171): Codanin-1 C-terminus
EF-G-binding_N (PF07299): Elongation factor G-binding protein, N-terminal
68 ERCC6oncoprotein160.32543.599Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
69 ERCC8oncoprotein100.51110.678WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4859 (PF16151, IPR032339): Domain of unknown function (DUF4859)
70 ERGoncoprotein100.3567.115Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
71 ESR1suppressor720.1691181.723Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
72 EWSR1oncoprotein450.193434.857RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
73 GPN1interactor200.43747.149ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
NB-ARC (PF00931, IPR002182): NB-ARC domain
74 GPN3interactor180.62713.537ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
75 GPS1interactor110.45515.972RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
76 GRB2oncoprotein160.32431.749SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
77 GTF2A2interactor31.0000TFIIA_gamma_C (PF02751, IPR015871): Transcription initiation factor IIA, gamma subunit
TFIIA_gamma_N (PF02268, IPR015872): Transcription initiation factor IIA, gamma subunit, helical domain
78 GTF2Binteractor260.36382.873Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
79 GTF2E1interactor180.42537.922DUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980)
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
TFIIE_alpha (PF02002, IPR024550): TFIIE alpha subunit
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
80 GTF2E2protein found in more fusions150.34131.127TFIIE_beta (PF02186, IPR003166): TFIIE beta subunit core domain
VCX_VCY (PF15231, IPR026653): Variable charge X/Y family
81 GTF2F1interactor300.34599.455TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
82 GTF2F2interactor240.42467.898TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
83 GTF2H1oncoprotein160.41738.687BSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
84 GTF2H4interactor130.6039.845Tfb2 (PF03849, IPR004598): Transcription factor Tfb2
85 GTF2Iinteractor100.5333.518GTF2I (PF02946, IPR004212): GTF2I-like repeat
86 GTF3C3interactor130.44914.096BUD22 (PF09073, IPR015158): BUD22
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1
DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369)
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
TPR_20 (PF14561): Tetratricopeptide repeat
87 H2AFXsuppressor210.39040.050Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
88 HDAC11interactor80.28611.188Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
89 HIRAsuppressor60.4006.458Hira (PF07569, IPR011494): TUP1-like enhancer of split
HIRA_B (PF09453, IPR019015): HIRA B motif
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
90 HIST1H1Concoprotein150.36230.355Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
91 HIST2H2BEinteractor210.29558.056Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
92 HMGN1interactor50.8330.222HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17
93 HNRNPRinteractor310.344134.570RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
94 HNRNPUinteractor480.232408.243CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
95 HTATSF1interactor90.5286.680BUD22 (PF09073, IPR015158): BUD22
Conotoxin (PF02950, IPR004214): Conotoxin
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
96 IFI16suppressor130.25624.441HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
97 ILF3oncoprotein310.37496.693dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
98 INTS1interactor180.40540.102DUF3677 (PF12432, IPR022145): Protein of unknown function (DUF3677)
99 INTS10interactor120.8034.383NA
100 INTS3interactor210.51435.276SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1
Fn_bind (PF02986, IPR004237): Fibronectin binding repeat
Ints3 (PF10189, IPR019333): Integrator complex subunit 3
101 INTS5interactor170.64016.769INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus
INTS5_C (PF14838, IPR029444): Integrator complex subunit 5 C-terminus
102 INTS6suppressor230.42774.151VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus
DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
103 IRF3suppressor90.4294.792IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
104 ITCHinteractor150.37421.259C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
105 IVNS1ABPprotein found in more fusions100.6942.142BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
106 IWS1interactor100.5339.771DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
107 KAT2Bprotein found in more fusions220.33363.781Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
108 KMT2Aoncoprotein190.28166.172AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
109 KMT2Doncoprotein40.6671.000DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Mnd1 (PF03962, IPR005647): Mnd1 family
PHD (PF00628, IPR019787, SM00249): PHD-finger
Pox_F17 (PF04767, IPR006854): DNA-binding 11 kDa phosphoprotein
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SET (PF00856, IPR001214, SM00317): SET domain
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
Fer4_4 (PF12800, IPR001450): 4Fe-4S binding domain
DUF4163 (PF13739, IPR025303): Domain of unknown function (DUF4163)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
Hydin_ADK (PF17213): Hydin Adenylate kinase-like domain
110 LEO1interactor200.44242.738Leo1 (PF04004, IPR007149): Leo1-like protein
PPP4R2 (PF09184, IPR015267): PPP4R2
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
111 LGR4interactor120.34516.8687tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
112 MAP4oncoprotein130.37221.768SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
113 MBD2oncoprotein90.3938.821API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3
MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD
114 MCM2oncoprotein400.291208.845AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
115 MCM3interactor150.41016.253MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
116 MCM7protein found in more fusions240.36860.746MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
117 MDC1suppressor290.33589.834FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
118 MED1interactor340.383155.621Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
119 MED10interactor270.63532.512Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
120 MED19interactor280.61837.407Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
121 MED20interactor190.7089.637Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex
122 MED21protein found in more fusions290.44292.849Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
123 MED23interactor280.46074.106Med23 (PF11573, IPR021629): Mediator complex subunit 23
124 MED26interactor390.382214.501Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
125 MED28interactor290.52961.444cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
Med28 (PF11594, IPR021640): Mediator complex subunit 28
126 MED29interactor300.55954.860Med29 (PF11568, IPR021018): Mediator complex subunit 29
127 MED30interactor200.71916.303Med30 (PF11315, IPR021019): Mediator complex subunit 30
128 MED4interactor350.334202.848Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
129 MED9interactor230.71115.882Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
130 MEN1suppressor90.41710.771Menin (PF05053, IPR007747): Menin
131 MLLT1oncoprotein100.5339.716DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
132 MNAT1oncoprotein140.52720.330MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1
Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
133 MOV10interactor300.172202.388AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
134 MTA2interactor190.26968.835BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain
DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
135 MYConcoprotein480.239386.459HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
136 MYO6protein found in more fusions70.5331.144BUD22 (PF09073, IPR015158): BUD22
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Rad9 (PF04139, IPR007268): Rad9
Sec62 (PF03839, IPR004728): Translocation protein Sec62
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
137 NABP1interactor80.5716.377tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
138 NEDD4suppressor180.36043.002Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
139 NELFAinteractor80.6793.109CathepsinC_exc (PF08773, IPR014882): Cathepsin C exclusion domain
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
140 NELFBprotein found in more fusions110.5786.415COBRA1 (PF06209, IPR010405): Cofactor of BRCA1 (COBRA1)
141 NELFEinteractor80.5716.471DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15
142 NEURL4interactor41.0000Neuralized (PF07177, IPR006573, SM00588): Neuralized
143 NF1suppressor50.6001.001MIF4G_like_2 (PF09090, IPR015174): MIF4G like
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
MOR2-PAG1_C (PF14225, IPR025481): Cell morphogenesis C-terminal
144 NFKB1suppressor120.43614.998Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
145 NFKBIAoncoprotein140.31929.038Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
146 NR0B2suppressor70.4763.637Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
147 NSD1oncoprotein80.3939.741PHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
SET (PF00856, IPR001214, SM00317): SET domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
148 NSMFinteractor21.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
DUF4347 (PF14252, IPR025592): Domain of unknown function (DUF4347)
149 NTRK1oncoprotein910.1262081.572I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
150 NXF1interactor460.146511.251NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
151 OBFC1interactor80.7861.933STN1_2 (PF09170, IPR015253): CST, Suppressor of cdc thirteen homolog, complex subunit STN1
RUN (PF02759, IPR004012, SM00593): RUN domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
Stn1 (PF10451, IPR018856): Telomere regulation protein Stn1
152 OBSL1interactor480.239270.863BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
153 PAF1oncoprotein200.42642.360Paf1 (PF03985, IPR007133): Paf1
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
154 PCIF1interactor30.6670.400WW (PF00397, IPR001202, SM00456): WW domain
PCIF1_WW (PF12237, IPR022035): Phosphorylated CTD interacting factor 1 WW domain
155 PCNAoncoprotein280.35996.938PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
156 PHF8interactor40.5000.991JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
PHD (PF00628, IPR019787, SM00249): PHD-finger
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
157 PIH1D1protein found in more fusions220.50240.611PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
158 PIN1suppressor190.32249.861Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
159 POLR2Binteractor680.219900.146RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
160 POLR2Cinteractor680.224904.659RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
161 POLR2Dinteractor380.403140.968RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
Tfb4 (PF03850, IPR004600): Transcription factor Tfb4
162 POLR2Eprotein found in more fusions560.298399.375RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain
RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain
163 POLR2Fprotein found in more fusions360.427121.732RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6
164 POLR2Ginteractor520.350307.767SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
165 POLR2Hinteractor370.422138.959RNA_pol_Rpb8 (PF03870, IPR005570, SM00658): RNA polymerase Rpb8
166 POLR2Iinteractor300.51378.780RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
CpXC (PF14353, IPR025682): CpXC protein
167 POLR2Jinteractor380.410123.190RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
168 POLR2Kinteractor190.75210.031DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
169 POLR2Linteractor240.61221.436RNA_pol_N (PF01194, IPR000268): RNA polymerases N / 8 kDa subunit
170 POLR2Minteractor200.67413.476GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
171 POLR3Ainteractor180.47128.548RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
172 POLR3Binteractor140.52714.764RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
173 PPP1CAsuppressor310.280145.727Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
174 PPP4R1interactor80.7502.304HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
175 PPP4R3Ainteractor60.6671.967Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1
WH1 (PF00568, IPR000697, SM00461): WH1 domain
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
176 PQBP1interactor50.7000.335WW (PF00397, IPR001202, SM00456): WW domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
177 PRMT5protein found in more fusions180.27946.052PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
178 PRPF19protein found in more fusions170.41727.829Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
179 PSMA5oncoprotein140.34132.904Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
180 PSMA6interactor90.5008.084Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
181 PSMB9interactor180.73520.881Proteasome (PF00227, IPR001353): Proteasome subunit
182 QKIprotein found in more fusions130.60612.336KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
183 RAD52oncoprotein60.7001.317Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
184 RALBP1interactor21.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
185 RECQL5oncoprotein160.58322.538DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5)
SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
TAtT (PF16811, IPR031823): TRAP transporter T-component
186 RELAoncoprotein330.242202.054DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
187 RPA1suppressor520.213478.648Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
188 RPAP2interactor280.42380.907NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
RPAP2_Rtr1 (PF04181, IPR007308): Rtr1/RPAP2 family
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
189 RPAP3interactor170.55115.734TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
190 RPRD1Binteractor220.53233.866CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
191 RPS20interactor150.40023.040Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
192 RUVBL2oncoprotein310.338105.117TIP49 (PF06068, IPR010339): TIP49 C-terminus
193 RXRAoncoprotein150.30835.694zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
194 SETD1Ainteractor60.5336.333E7 (PF00527, IPR000148): E7 protein, Early protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SET (PF00856, IPR001214, SM00317): SET domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
195 SETD1Binteractor40.6672.000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SET (PF00856, IPR001214, SM00317): SET domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
4HBT_3 (PF13622): Thioesterase-like superfamily
SOBP (PF15279, IPR026092): Sine oculis-binding protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
196 SETD2suppressor50.8330.500DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
SET (PF00856, IPR001214, SM00317): SET domain
SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
WW (PF00397, IPR001202, SM00456): WW domain
DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592)
197 SETXinteractor60.6672.944ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
198 SIRT7interactor400.167326.329DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
199 SMARCA2suppressor190.48031.146DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
200 SMARCA4suppressor280.278124.020DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
201 SMARCB1suppressor170.42526.904SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
202 SMC1Aoncoprotein240.32472.643SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
203 SMC3oncoprotein220.31272.131SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
204 SMN1interactor160.21939.925SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
205 SMURF1interactor190.24248.299C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
206 SMYD3oncoprotein30.6670.100SET (PF00856, IPR001214, SM00317): SET domain
207 SNAR-B2interactor21.0000NA
208 SND1interactor200.42641.306TUDOR (PF00567, IPR002999, SM00333): Tudor domain
SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue
209 SRConcoprotein270.366119.341Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
210 SRRTinteractor110.5278.265ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546)
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
211 SRSF2oncoprotein220.32955.654RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
212 SSRP1interactor220.38550.316Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SSrecog (PF03531, IPR024954): Structure-specific recognition protein (SSRP1)
YABBY (PF04690, IPR006780): YABBY protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
Coilin_N (PF15862, IPR031722): Coilin N-terminus
213 SSU72interactor40.6670.536Ssu72 (PF04722, IPR006811): Ssu72-like protein
214 SUB1interactor130.28814.403Dehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
215 SUPT4H1interactor100.4676.919Spt4 (PF06093, IPR022800): Spt4/RpoE2 zinc finger
216 SUPT5Hinteractor460.227414.887KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
217 SUPT6Hinteractor200.36847.191Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SH2_2 (PF14633, IPR000980): SH2 domain
HHH_7 (PF14635, IPR032706): Helix-hairpin-helix motif
YqgF (PF14639, IPR028231): Holliday-junction resolvase-like of SPT6
HTH_44 (PF14641, IPR028088): Helix-turn-helix DNA-binding domain of SPT6
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DLD (PF14878, IPR027999): Death-like domain of SPT6
218 TADA2Ainteractor200.38960.690SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
219 TAF10interactor100.33316.631TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit
220 TAF11interactor110.41812.501CENP-X (PF09415, IPR018552): CENP-S associating Centromere protein X
TAFII28 (PF04719, IPR006809): hTAFII28-like protein conserved region
221 TAF15oncoprotein180.31435.418API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Presenilin (PF01080, IPR001108): Presenilin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
222 TBPinteractor320.239208.944TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
223 TCEA1oncoprotein290.298128.336Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
224 TCEB3suppressor200.58922.052Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
225 TCERG1interactor130.37215.630FF (PF01846, IPR002713, SM00441): FF domain
WW (PF00397, IPR001202, SM00456): WW domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
FAM150 (PF15129, IPR029364): FAM150 family
226 TCTN3interactor40.6670.341DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
227 TDRD3interactor50.4001.406RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472)
228 TRIP4interactor140.52715.667ASCH (PF04266, IPR007374, SM01022): ASCH domain
UxaC (PF02614, IPR003766): Glucuronate isomerase
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
229 TTKinteractor70.5332.112Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Pkinase (PF00069, IPR000719): Protein kinase domain
RIO1 (PF01163, IPR018934): RIO1 family
T3SS_basalb_I (PF17001, IPR012670): Type III secretion basal body protein I, YscI, HrpB, PscI
Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
230 U2AF2protein found in more fusions300.39783.975RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
231 UBE2L3interactor130.30320.401UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
232 UBE3Binteractor100EAL (PF00563, IPR001633, SM00052): EAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
233 UBN1interactor31.0000Cellulose_synt (PF03552, IPR005150): Cellulose synthase
HUN (PF08729, IPR014840): HPC2 and ubinuclein domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
UBN_AB (PF14075, IPR026947): Ubinuclein conserved middle domain
234 UNKinteractor160.25845.724MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
235 USPL1interactor30.6670.091zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
Peptidase_C98 (PF15499, IPR028890): Ubiquitin-specific peptidase-like, SUMO isopeptidase
DUF4650 (PF15509, IPR029388): Domain of unknown function (DUF4650)
236 VDRsuppressor160.37129.263zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
237 VHLsuppressor270.295105.554Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
238 VWA9interactor71.0000VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
239 WACprotein found in more fusions40.6670.500DUF1319 (PF07028, IPR010746): Protein of unknown function (DUF1319)
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
WW (PF00397, IPR001202, SM00456): WW domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
240 WDHD1interactor60.8000.598PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
241 WDR82oncoprotein100.37818.552MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
242 WWOXsuppressor260.212115.039adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
243 XAB2interactor140.24237.884NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
HAT (PF02184, IPR003107, SM00386): HAT (Half-A-TPR) repeat
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
244 XPAoncoprotein130.32132.421XPA_C (PF05181, IPR022656): XPA protein C-terminus
XPA_N (PF01286, IPR022652): XPA protein N-terminal
MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
245 XPO1interactor590.165862.138CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
246 XRCC5suppressor310.34094.661Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
247 XRN2interactor180.45819.863XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
248 YAP1suppressor130.30825.689Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
249 ZC3H13interactor170.60325.241FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial
250 ZNF326interactor130.33326.968AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95)
DUF678 (PF05077, IPR007769): Protein of unknown function (DUF678)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
251 ZNF74interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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