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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PITX1, PRKD2 (from a repository: Wed Jun 6 16:24:59 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)58
The number (and %) of the onco-proteins16 (27.59 %)
The number (and %) of the tumor suppressors4 (6.90 %)
Total number of binary PPIs (saturation %)140 (8.47 %)
The number (and %) of affected PPIs57 (40.71 %)
The number of possible different fusions13
PPI diameter4
PPI radius2
The average degree of PPI4.103
Assortativity coefficient-0.4665
The network average Clustering coefficient0.386
The number (and %) of a zero Clustering coefficients21 (36.21 %)
The number (and %) of a zero Betweenness Centrality26 (44.83 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: PRKD2,PITX1 All fusions
: BE839314;
Proteins found in more fusions GORASP1 (see 1 fusions); RXRA (see 2 fusions); HDAC7 (see 1 fusions); RFFL (see 1 fusions); HDAC5 (see 1 fusions); EWSR1 (see 2 fusions); MAGED1 (see 1 fusions); HSP90AA1 (see 2 fusions); DVL3 (see 1 fusions); GRIP1 (see 2 fusions); SMAD3 (see 3 fusions); RBPMS (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 PRKD2parental protein300.0531486.392ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
2 PITX1parental protein270.0631469.243Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
3 ALG13interactor100Glyco_tran_28_C (PF04101, IPR007235): Glycosyltransferase family 28 C-terminal domain
OTU (PF02338, IPR003323): OTU-like cysteine protease
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
4 C1orf94interactor50.8330.991DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
5 CASKinteractor30.66714.500L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
6 CDK10interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
7 CDX4interactor100Caudal_act (PF04731, IPR006820): Caudal like protein activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
8 DSToncoprotein100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
9 DVL3protein found in more fusions40.6675.666DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
10 EGR1suppressor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432)
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
11 EWSR1oncoprotein80.333106.458RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
12 GLRX3interactor50.50078.813Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
13 GORASP1protein found in more fusions31.0000GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
14 GRIP1protein found in more fusions40.33323.719PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
15 HDAC5protein found in more fusions80.33375.166Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
16 HDAC7protein found in more fusions41.0000Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
17 HEY1oncoprotein204.862Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
18 HGSinteractor40.33340.381FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
19 HSP90AA1oncoprotein50.8331.417HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
20 IFNAR1oncoprotein100Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
21 IPO13interactor205.666IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
22 LZTS2suppressor40.66720.154CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
23 MAGED1protein found in more fusions60.50049.217MAGE (PF01454, IPR002190): MAGE family
24 MGAT5Binteractor30.6670.667Glyco_transf_18 (PF15024): Glycosyltransferase family 18
25 MTF2interactor204.862PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
26 NGDNinteractor100Sas10_Utp3 (PF04000, IPR007146): Sas10/Utp3/C1D family
FAM176 (PF14851): FAM176 family
TMEM247 (PF15444, IPR029200): Transmembrane protein 247
27 NGRNinteractor100Neugrin (PF06413, IPR010487): Neugrin
28 NR5A1interactor21.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
29 NTRK1oncoprotein170.133388.170I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
30 PDLIM7interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
31 PFDN1interactor100Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
32 PHYHIPinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
33 PLSCR1interactor40.50030.890Scramblase (PF03803, IPR005552): Scramblase
34 POU1F1interactor100Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Lsr2 (PF11774, IPR024412): Lsr2
35 PRKD3interactor30.6670.917PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
36 PRR20Ainteractor41.0000PRR20 (PF15708, IPR031439): Proline-rich protein family 20
37 PSG3interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
38 RAE1interactor30.6670.667Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
39 RARBsuppressor21.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
40 RBPMSprotein found in more fusions100.38926.066RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
41 RFFLprotein found in more fusions200FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Armet (PF10208, IPR019345): Degradation arginine-rich protein for mis-folding
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
42 RFX6interactor100RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
43 RHOXF2interactor70.6006.333DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
44 RNF31interactor40.3336.881Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
PUB (PF09409, IPR018997): PUB domain
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
45 RRBP1interactor30.66721.930Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Pentapeptide_2 (PF01469, IPR002989): Pentapeptide repeats (8 copies)
Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region
RTBV_P46 (PF06216, IPR009347): Rice tungro bacilliform virus P46 protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
UPF0767 (PF15990, IPR031933): UPF0767 family
46 RXRAoncoprotein40.6671.286zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
47 SEC23IPinteractor31.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
WWE (PF02825, IPR004170, SM00678): WWE domain
48 SMAD3oncoprotein100.056272.297MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
49 SMARCA2suppressor100DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
50 SNRNP70interactor40.5007.355RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
51 SPAG8interactor100Zip (PF02535, IPR003689): ZIP Zinc transporter
52 TRAPPC2interactor31.0000Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region
53 TRIM23interactor200Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
FemAB (PF02388, IPR003447): FemAB family
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
54 TSC22D4interactor204.862AflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
55 UPF2interactor40.6675.666DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
56 XPO1interactor120.242726.211CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
57 YWHAQinteractor50.50018.29414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
58 ZBTB32interactor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ALG13interactorGlyco_tran_28_C (PF04101, IPR007235): Glycosyltransferase family 28 C-terminal domain
OTU (PF02338, IPR003323): OTU-like cysteine protease
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
BE839314
2 C1orf94interactorDUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)BE839314
3 CDK10interactorPkinase (PF00069, IPR000719): Protein kinase domainBE839314
4 CDX4interactorCaudal_act (PF04731, IPR006820): Caudal like protein activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
BE839314
5 DSToncoproteinCH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BE839314
6 DVL3interactorDEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
BE839314
7 EGR1suppressorzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432)
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
BE839314
8 EWSR1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
BE839314
9 GLRX3interactorGlutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
BE839314
10 GORASP1interactorGRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domainBE839314
11 GRIP1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)BE839314
12 HDAC7interactorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
BE839314
13 HEY1oncoproteinHairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
BE839314
14 HSP90AA1oncoproteinHATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
BE839314
15 IFNAR1oncoproteinInterfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
BE839314
16 LZTS2suppressorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
BE839314
17 MAGED1interactorMAGE (PF01454, IPR002190): MAGE familyBE839314
18 MGAT5BinteractorGlyco_transf_18 (PF15024): Glycosyltransferase family 18BE839314
19 MTF2interactorPHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
BE839314
20 NGDNinteractorSas10_Utp3 (PF04000, IPR007146): Sas10/Utp3/C1D family
FAM176 (PF14851): FAM176 family
TMEM247 (PF15444, IPR029200): Transmembrane protein 247
BE839314
21 NGRNinteractorNeugrin (PF06413, IPR010487): NeugrinBE839314
22 NR5A1interactorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
BE839314
23 PDLIM7interactorLIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
BE839314
24 PFDN1interactorPrefoldin_2 (PF01920, IPR002777): Prefoldin subunitBE839314
25 PHYHIPinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domainBE839314
26 PITX1parental proteinForkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
BE839314
27 PLSCR1interactorScramblase (PF03803, IPR005552): ScramblaseBE839314
28 POU1F1interactorPou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Lsr2 (PF11774, IPR024412): Lsr2
BE839314
29 PRKD2parental proteinABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
BE839314
30 PRR20AinteractorPRR20 (PF15708, IPR031439): Proline-rich protein family 20BE839314
31 RAE1interactorExonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
BE839314
32 RBPMSinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)BE839314
33 RFFLinteractorFYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Armet (PF10208, IPR019345): Degradation arginine-rich protein for mis-folding
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
BE839314
34 RFX6interactorRFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
BE839314
35 RHOXF2interactorDUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
BE839314
36 RRBP1interactorFez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Pentapeptide_2 (PF01469, IPR002989): Pentapeptide repeats (8 copies)
Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region
RTBV_P46 (PF06216, IPR009347): Rice tungro bacilliform virus P46 protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
UPF0767 (PF15990, IPR031933): UPF0767 family
BE839314
37 RXRAoncoproteinzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
BE839314
38 SEC23IPinteractorDDHD (PF02862, IPR004177, SM01127): DDHD domain
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
WWE (PF02825, IPR004170, SM00678): WWE domain
BE839314
39 SMAD3oncoproteinMH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
BE839314
40 SMARCA2suppressorDUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
BE839314
41 SNRNP70interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
BE839314
42 SPAG8interactorZip (PF02535, IPR003689): ZIP Zinc transporterBE839314
43 TRAPPC2interactorSedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved regionBE839314
44 TRIM23interactorArf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
FemAB (PF02388, IPR003447): FemAB family
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
BE839314
45 TSC22D4interactorAflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
BE839314
46 UPF2interactorDDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
BE839314
47 YWHAQinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinBE839314

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