1 |
PIK3R1 | parental protein | 145 | 0.079 | 12813.777 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
2 |
ABI1 | oncoprotein | 5 | 1.000 | 0 | Abi_HHR (PF07815, IPR012849): Abl-interactor HHR Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) PRIMA1 (PF16101): Proline-rich membrane anchor 1 ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension |
3 |
ABL1 | oncoprotein | 33 | 0.371 | 135.086 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
4 |
ADAM12 | interactor | 1 | 0 | 0 | Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich Disintegrin (PF00200, IPR001762, SM00050): Disintegrin |
5 |
ADAMTS2 | interactor | 1 | 0 | 0 | ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1 Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain |
6 |
AGAP2 | interactor | 1 | 0 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain Ras (PF00071, IPR001806, SM00173): Ras family Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
7 |
ALK | oncoprotein | 13 | 0.436 | 15.216 | MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
8 |
ALOX5 | oncoprotein | 2 | 1.000 | 0 | Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain |
9 |
APPL1 | interactor | 14 | 0.372 | 28.384 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region PH (PF00169, IPR001849, SM00233): PH domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) BAR_3 (PF16746): BAR domain of APPL family |
10 |
ARAF | oncoprotein | 3 | 0.667 | 1.000 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
11 |
ARHGAP1 | interactor | 5 | 0.667 | 1.333 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain |
12 |
ARHGAP17 | interactor | 8 | 0.750 | 1.036 | BAR (PF03114, IPR004148, SM00721): BAR domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain |
13 |
ARHGAP32 | oncoprotein | 13 | 0.667 | 4.777 | PX (PF00787, IPR001683, SM00312): PX domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RPEL (PF02755, IPR004018, SM00707): RPEL repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain |
14 |
AXL | oncoprotein | 7 | 0.619 | 3.893 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2627 (PF11118, IPR020138): Protein of unknown function (DUF2627) Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
15 |
BCAR1 | oncoprotein | 20 | 0.479 | 31.527 | Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) Caskin1-CID (PF16600): Caskin1 CASK-interaction domain |
16 |
BRCA1 | oncoprotein | 10 | 0.417 | 9.259 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
17 |
CBL | oncoprotein | 56 | 0.253 | 584.302 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
18 |
CBLB | oncoprotein | 25 | 0.500 | 39.348 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
19 |
CCL14 | interactor | 1 | 0 | 0 | IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like |
20 |
CD244 | interactor | 2 | 1.000 | 0 | Receptor_2B4 (PF11465, IPR024303): Natural killer cell receptor 2B4 WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 Ig_2 (PF13895, IPR007110): Immunoglobulin domain |
21 |
CD28 | interactor | 6 | 0.733 | 1.282 | V-set_2 (PF15910, IPR013106): ICOS V-set domain |
22 |
CD3E | interactor | 8 | 0.500 | 5.619 | ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter Ig_5 (PF16681): Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain |
23 |
CD40 | protein found in more fusions | 4 | 1.000 | 0 | Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
24 |
CD7 | interactor | 2 | 1.000 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
25 |
CHAF1A | interactor | 4 | 0.667 | 0.500 | CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA |
26 |
CLNK | interactor | 6 | 0.867 | 0.619 | SH2 (PF00017, IPR000980, SM00252): SH2 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
27 |
CMIP | interactor | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat Microtub_bd (PF16796, IPR031852): Microtubule binding |
28 |
CRK | oncoprotein | 42 | 0.279 | 265.041 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
29 |
CRKL | oncoprotein | 29 | 0.419 | 64.024 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
30 |
CSF1R | oncoprotein | 9 | 0.694 | 1.626 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
31 |
CSF2RA | interactor | 2 | 1.000 | 0 | IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding |
32 |
CTNNB1 | oncoprotein | 20 | 0.295 | 77.257 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
33 |
CUL3 | protein found in more fusions | 13 | 0.530 | 12.098 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
34 |
CXCL2 | interactor | 1 | 0 | 0 | IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like |
35 |
CYP4A11 | interactor | 1 | 0 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
36 |
DAB2IP | oncoprotein | 5 | 0.400 | 3.267 | C2 (PF00168, IPR000008, SM00239): C2 domain PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498) |
37 |
DLX2 | interactor | 2 | 0 | 0 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG DLL_N (PF12413, IPR022135): Homeobox protein distal-less-like N terminal |
38 |
DOK1 | suppressor | 15 | 0.615 | 9.427 | IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
39 |
EFNB2 | interactor | 5 | 0.600 | 2.000 | Ephrin (PF00812, IPR001799): Ephrin TMEM132D_C (PF15706, IPR031436): Mature oligodendrocyte transmembrane protein, TMEM132D, C-term |
40 |
EGFR | oncoprotein | 58 | 0.246 | 599.170 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
41 |
EP300 | oncoprotein | 13 | 0.394 | 24.785 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
42 |
EPHA2 | oncoprotein | 11 | 0.644 | 9.454 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
43 |
EPN1 | interactor | 6 | 0.533 | 3.440 | ENTH (PF01417, IPR001026, SM00273): ENTH domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
44 |
EPOR | oncoprotein | 13 | 0.615 | 6.874 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
45 |
ERBB2 | oncoprotein | 34 | 0.390 | 138.570 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
46 |
ERBB3 | oncoprotein | 24 | 0.443 | 55.396 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
47 |
ESR1 | oncoprotein | 23 | 0.320 | 80.412 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
48 |
EZR | protein found in more fusions | 9 | 0.536 | 5.421 | DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
49 |
FASLG | interactor | 11 | 0.418 | 14.247 | PAP_PilO (PF06864, IPR009663): Pilin accessory protein (PilO) TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
50 |
FBXL2 | interactor | 2 | 1.000 | 0 | Ste50p-SAM (PF09235, IPR015316): Ste50p, sterile alpha motif LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
51 |
FCGR2A | interactor | 5 | 0.800 | 0.375 | DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827) Ig_2 (PF13895, IPR007110): Immunoglobulin domain ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator |
52 |
FER | protein found in more fusions | 7 | 0.867 | 0.536 | DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain Glyco_transf_28 (PF03033, IPR004276): Glycosyltransferase family 28 N-terminal domain PEP-utilisers_N (PF05524, IPR008731): PEP-utilising enzyme, N-terminal Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
53 |
FES | oncoprotein | 4 | 1.000 | 0 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Remorin_C (PF03763, IPR005516): Remorin, C-terminal region SH2 (PF00017, IPR000980, SM00252): SH2 domain Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein |
54 |
FGFR1 | oncoprotein | 13 | 0.409 | 12.488 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
55 |
FGFR2 | oncoprotein | 5 | 1.000 | 0 | Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
56 |
FLT3 | oncoprotein | 5 | 0.833 | 0.118 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
57 |
FYN | oncoprotein | 34 | 0.242 | 185.349 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
58 |
GAB1 | oncoprotein | 10 | 0.889 | 0.579 | PH (PF00169, IPR001849, SM00233): PH domain |
59 |
GAB2 | oncoprotein | 18 | 0.478 | 18.125 | PH (PF00169, IPR001849, SM00233): PH domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone |
60 |
GNAQ | oncoprotein | 2 | 1.000 | 0 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
61 |
GRB10 | oncoprotein | 11 | 0.455 | 12.136 | BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos |
62 |
GRB2 | oncoprotein | 69 | 0.211 | 955.284 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
63 |
GSPT1 | oncoprotein | 2 | 1.000 | 0 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
64 |
HCST | interactor | 1 | 0 | 0 | DAP10 (PF07213, IPR009861): DAP10 membrane protein |
65 |
HDAC3 | oncoprotein | 10 | 0.500 | 10.324 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
66 |
HOXA1 | interactor | 2 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
67 |
HRAS | oncoprotein | 7 | 0.476 | 6.036 | Ras (PF00071, IPR001806, SM00173): Ras family |
68 |
HTT | protein found in more fusions | 8 | 0.381 | 8.552 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
69 |
IFNAR1 | oncoprotein | 3 | 0.667 | 0.200 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
70 |
IGF1R | oncoprotein | 16 | 0.558 | 14.968 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain |
71 |
IL1R1 | interactor | 1 | 0 | 0 | TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
72 |
IL6ST | oncoprotein | 10 | 0.733 | 2.001 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
73 |
INPP5D | interactor | 15 | 0.495 | 25.195 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SH2 (PF00017, IPR000980, SM00252): SH2 domain |
74 |
INPPL1 | oncoprotein | 13 | 0.692 | 8.547 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
75 |
IRS1 | interactor | 21 | 0.452 | 39.604 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
76 |
IRS2 | oncoprotein | 14 | 0.462 | 21.931 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
77 |
IRS4 | interactor | 13 | 0.487 | 18.769 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence PH_11 (PF15413): Pleckstrin homology domain |
78 |
ITSN1 | interactor | 10 | 0.472 | 7.834 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
79 |
JAK2 | oncoprotein | 25 | 0.428 | 59.663 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
80 |
KHDRBS1 | protein found in more fusions | 18 | 0.353 | 25.089 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
81 |
KIT | oncoprotein | 20 | 0.426 | 46.742 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
82 |
LAT | interactor | 15 | 0.543 | 16.882 | LAT (PF15234, IPR008359): Linker for activation of T-cells |
83 |
LCK | oncoprotein | 25 | 0.236 | 93.595 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
84 |
LCP2 | interactor | 13 | 0.692 | 5.915 | SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SDA1 (PF05285, IPR007949): SDA1 SH2 (PF00017, IPR000980, SM00252): SH2 domain |
85 |
LTK | interactor | 2 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
86 |
MAP3K5 | protein found in more fusions | 8 | 0.524 | 6.550 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
87 |
MED28 | interactor | 6 | 0.800 | 0.191 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
88 |
NCK1 | oncoprotein | 24 | 0.312 | 69.016 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
89 |
NCL | protein found in more fusions | 8 | 0.667 | 3.562 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
90 |
NFKBIA | oncoprotein | 5 | 0.600 | 3.667 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
91 |
NPM1 | oncoprotein | 12 | 0.491 | 15.662 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
92 |
NTRK1 | oncoprotein | 40 | 0.270 | 290.381 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
93 |
NTRK2 | oncoprotein | 5 | 0.500 | 1.820 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
94 |
NYAP2 | interactor | 1 | 0 | 0 | NYAP_N (PF15439): Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter TMEM247 (PF15444, IPR029200): Transmembrane protein 247 NYAP_C (PF15452, IPR029353): Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter |
95 |
PCBP1 | oncoprotein | 5 | 0.700 | 1.033 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
96 |
PDE4D | oncoprotein | 8 | 0.476 | 4.890 | Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase |
97 |
PDGFRA | oncoprotein | 12 | 0.655 | 4.779 | Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain LAT (PF15234, IPR008359): Linker for activation of T-cells |
98 |
PDGFRB | oncoprotein | 15 | 0.604 | 6.540 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain Ig_3 (PF13927): Immunoglobulin domain TonB_N (PF16031): TonB N-terminal region |
99 |
PECAM1 | oncoprotein | 9 | 0.464 | 3.913 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
100 |
PIK3CA | oncoprotein | 22 | 0.277 | 102.536 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
101 |
PIK3CB | oncoprotein | 16 | 0.400 | 39.401 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) RWD (PF05773, IPR006575, SM00591): RWD domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase Tom37_C (PF11801, IPR019564): Tom37 C-terminal domain DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381) |
102 |
PIK3CD | oncoprotein | 5 | 0.500 | 3.833 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
103 |
PIK3R2 | oncoprotein | 40 | 0.262 | 338.207 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
104 |
PLCG2 | interactor | 11 | 0.636 | 3.599 | C2 (PF00168, IPR000008, SM00239): C2 domain EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
105 |
PRMT2 | interactor | 4 | 0.500 | 1.667 | PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase SH3_9 (PF14604, IPR001452): Variant SH3 domain |
106 |
PTGER3 | interactor | 4 | 0.833 | 0.200 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) FtsX (PF02687, IPR003838): FtsX-like permease family |
107 |
PTK2 | protein found in more fusions | 25 | 0.507 | 39.329 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
108 |
PTPN11 | oncoprotein | 35 | 0.358 | 137.854 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
109 |
PTPN6 | oncoprotein | 18 | 0.477 | 23.782 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus |
110 |
PXK | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase PX (PF00787, IPR001683, SM00312): PX domain WH2 (PF02205, IPR003124, SM00246): WH2 motif Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor MNR (PF15718, IPR031447): Protein moonraker |
111 |
PXN | oncoprotein | 14 | 0.604 | 7.517 | LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family |
112 |
RAB5A | oncoprotein | 5 | 0.500 | 2.119 | Ras (PF00071, IPR001806, SM00173): Ras family |
113 |
RRAS2 | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
114 |
RXRA | oncoprotein | 6 | 0.700 | 1.015 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
115 |
SELPLG | protein found in more fusions | 3 | 1.000 | 0 | EVI2A (PF05399, IPR008608): Ectropic viral integration site 2A protein (EVI2A) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF4689 (PF15755, IPR031499): Domain of unknown function (DUF4689) |
116 |
SH2D2A | interactor | 9 | 0.778 | 2.275 | SH2 (PF00017, IPR000980, SM00252): SH2 domain |
117 |
SH3KBP1 | protein found in more fusions | 26 | 0.390 | 86.206 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
118 |
SHB | interactor | 10 | 0.689 | 3.824 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein SH2 (PF00017, IPR000980, SM00252): SH2 domain Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region |
119 |
SHC1 | oncoprotein | 35 | 0.339 | 142.423 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
120 |
SIRT1 | oncoprotein | 9 | 0.607 | 3.874 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
121 |
SOCS1 | oncoprotein | 22 | 0.364 | 62.616 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
122 |
SOCS6 | interactor | 8 | 0.679 | 3.268 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
123 |
SOS1 | oncoprotein | 22 | 0.411 | 48.421 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif |
124 |
SQSTM1 | oncoprotein | 12 | 0.327 | 26.208 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
125 |
SRC | oncoprotein | 46 | 0.229 | 407.086 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
126 |
STAT3 | oncoprotein | 29 | 0.310 | 136.521 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
127 |
SYK | oncoprotein | 30 | 0.372 | 116.346 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
128 |
SYN1 | protein found in more fusions | 5 | 1.000 | 0 | Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain Synapsin_N (PF10581, IPR019736): Synapsin N-terminal DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain |
129 |
SYNM | suppressor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
130 |
TGFBR1 | oncoprotein | 7 | 0.429 | 5.650 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
131 |
TGFBR2 | oncoprotein | 10 | 0.467 | 9.731 | ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
132 |
TLR3 | interactor | 2 | 1.000 | 0 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
133 |
TMEM17 | interactor | 8 | 0.250 | 13.133 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043) |
134 |
TNFRSF1A | oncoprotein | 16 | 0.505 | 20.263 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
135 |
TNIP1 | interactor | 5 | 0.500 | 3.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Filament (PF00038, IPR001664): Intermediate filament protein HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) FlxA (PF14282, IPR025577): FlxA-like protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
136 |
TNS4 | interactor | 4 | 0.833 | 0.111 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
137 |
TTR | interactor | 2 | 0 | 0 | Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family |
138 |
TUBA1B | interactor | 5 | 0.800 | 0.500 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
139 |
TYRO3 | oncoprotein | 4 | 0.667 | 2.000 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain DUF4229 (PF14012, IPR025323): Protein of unknown function (DUF4229) |
140 |
VAV1 | oncoprotein | 25 | 0.410 | 60.755 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain |
141 |
VSIG4 | interactor | 3 | 1.000 | 0 | EMP70 (PF02990, IPR004240): Endomembrane protein 70 V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
142 |
WAS | oncoprotein | 12 | 0.576 | 6.352 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain WH1 (PF00568, IPR000697, SM00461): WH1 domain WH2 (PF02205, IPR003124, SM00246): WH2 motif PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
143 |
YWHAG | protein found in more fusions | 12 | 0.418 | 20.634 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
144 |
ZAP70 | interactor | 20 | 0.520 | 29.706 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
145 |
ZDHHC17 | protein found in more fusions | 6 | 0.400 | 3.733 | zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat Ank_4 (PF13637): Ankyrin repeats (many copies) |