Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PTPN21, PIGK (from a repository: Thu Aug 8 22:57:17 2019)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins2 (11.11 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)41 (26.80 %)
The number (and %) of affected PPIs16 (39.02 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI4.444
Assortativity coefficient-0.0457
The network average Clustering coefficient0.658
The number (and %) of a zero Clustering coefficients3 (16.67 %)
The number (and %) of a zero Betweenness Centrality10 (55.56 %)


List of the fusions

PPI for parental proteins: PIGK,PTPN21 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PIGKparental protein120.34860.567Peptidase_C13 (PF01650, IPR001096): Peptidase C13 family
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
2 PTPN21parental protein40.16710.000FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PRIMA1 (PF16101): Proline-rich membrane anchor 1
3 ALPPinteractor21.0000Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase
4 B3GNT3interactor21.0000Galactosyl_T (PF01762, IPR002659): Galactosyltransferase
5 BMXinteractor21.0000BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PH_8 (PF15409): Pleckstrin homology domain
6 CANXinteractor31.0000Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
7 FBXO6interactor50.6003.667FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
8 GPAA1interactor70.8101.900Gaa1 (PF04114, IPR007246): Gaa1-like, GPI transamidase component
YlaH (PF14036, IPR025620): YlaH-like protein
9 KIF1Cinteractor100FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
10 LYPD3oncoprotein41.0000DUF753 (PF05444, IPR008472): Protein of unknown function (DUF753)
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
11 PARD6Binteractor100PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
12 PIGSinteractor80.6795.900PIG-S (PF10510, IPR019540): Phosphatidylinositol-glycan biosynthesis class S protein
13 PIGTinteractor60.9330.400Gpi16 (PF04113, IPR007245): Gpi16 subunit, GPI transamidase component
14 PIGUinteractor80.6437.900PIG-U (PF06728, IPR009600): GPI transamidase subunit PIG-U
15 PRSS50interactor51.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
16 SRConcoprotein31.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
17 TCTN3interactor70.6675.667DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
18 ULBP2interactor100MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2

B a c k    t o    T o p ⇑