1 |
PIAS2 | parental protein | 71 | 0.077 | 3324.994 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
2 |
ACY3 | interactor | 2 | 0 | 0 | AstE_AspA (PF04952, IPR007036): Succinylglutamate desuccinylase / Aspartoacylase family |
3 |
ADA | interactor | 2 | 1.000 | 0 | A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase |
4 |
AKT1 | oncoprotein | 11 | 0.400 | 18.601 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
5 |
AR | oncoprotein | 13 | 0.530 | 13.727 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
6 |
ARNT | oncoprotein | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
7 |
C1QA | oncoprotein | 1 | 0 | 0 | C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
8 |
CCHCR1 | interactor | 5 | 0.500 | 2.167 | HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR) |
9 |
CCNDBP1 | suppressor | 3 | 0.667 | 0.667 | CheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea GCIP (PF13324): Grap2 and cyclin-D-interacting |
10 |
CDCA8 | interactor | 3 | 1.000 | 0 | Borealin (PF10512, IPR018867): Cell division cycle-associated protein 8 Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 |
11 |
CDKN2A | suppressor | 7 | 0.762 | 2.233 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
12 |
CDKN2B | suppressor | 1 | 0 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
13 |
CHMP4B | interactor | 4 | 1.000 | 0 | Snf7 (PF03357, IPR005024): Snf7 |
14 |
CLDN2 | interactor | 2 | 1.000 | 0 | PMP22_Claudin (PF00822, IPR004031): PMP-22/EMP/MP20/Claudin family DUF4064 (PF13273, IPR025273): Protein of unknown function (DUF4064) |
15 |
CTBP1 | protein found in more fusions | 6 | 0.600 | 1.686 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
16 |
DNMT3A | suppressor | 4 | 0.833 | 0.286 | DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain |
17 |
ESR1 | suppressor | 13 | 0.394 | 31.875 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
18 |
ESR2 | suppressor | 3 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
19 |
FLI1 | oncoprotein | 5 | 0.700 | 1.002 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
20 |
GFAP | protein found in more fusions | 5 | 0.500 | 1.833 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
21 |
GLUL | protein found in more fusions | 4 | 1.000 | 0 | Gln-synt_C (PF00120, IPR008146): Glutamine synthetase, catalytic domain Gln-synt_N (PF03951, IPR008147): Glutamine synthetase, beta-Grasp domain |
22 |
GOLGA2 | interactor | 6 | 0.400 | 7.333 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
23 |
GTF2I | interactor | 4 | 1.000 | 0 | GTF2I (PF02946, IPR004212): GTF2I-like repeat |
24 |
GTF2IRD1 | interactor | 1 | 0 | 0 | GTF2I (PF02946, IPR004212): GTF2I-like repeat SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
25 |
HIC1 | suppressor | 6 | 0.700 | 1.100 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
26 |
HUWE1 | oncoprotein | 5 | 1.000 | 0 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
27 |
IFIH1 | interactor | 1 | 0 | 0 | ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RIG-I_C-RD (PF11648, IPR021673): C-terminal domain of RIG-I CARD_2 (PF16739, IPR031964): Caspase recruitment domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
28 |
JUN | oncoprotein | 16 | 0.410 | 41.984 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
29 |
LMNB1 | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain |
30 |
MAPK8 | oncoprotein | 9 | 0.571 | 7.387 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
31 |
MAPKAPK2 | oncoprotein | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
32 |
MBD1 | interactor | 2 | 1.000 | 0 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain |
33 |
MITF | oncoprotein | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
34 |
MSX2 | interactor | 3 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
35 |
MX2 | interactor | 2 | 0 | 0 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
36 |
MYC | oncoprotein | 13 | 0.530 | 17.321 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
37 |
NAV2 | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Laminin_II (PF06009, IPR010307): Laminin Domain II KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding AAA_14 (PF13173): AAA domain |
38 |
NR3C1 | protein found in more fusions | 10 | 0.556 | 13.621 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
39 |
PARK7 | suppressor | 8 | 0.714 | 2.172 | DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family |
40 |
PAXIP1 | interactor | 4 | 0.500 | 2.167 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
41 |
PGR | suppressor | 3 | 1.000 | 0 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
42 |
PHC1 | interactor | 6 | 0.800 | 0.900 | GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) FSA_C (PF10479, IPR018863): Fragile site-associated protein C-terminus zf-CGNR (PF11706, IPR021005): CGNR zinc finger PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 |
43 |
PIAS1 | suppressor | 28 | 0.225 | 183.116 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
44 |
PIAS4 | interactor | 11 | 0.473 | 14.114 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
45 |
PLAG1 | oncoprotein | 4 | 0.667 | 0.382 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
46 |
PLAGL1 | suppressor | 5 | 0.900 | 0.154 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
47 |
PML | suppressor | 19 | 0.386 | 55.308 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
48 |
PRKAB2 | interactor | 4 | 0.667 | 0.667 | AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase |
49 |
RUFY1 | interactor | 2 | 0 | 0 | DM (PF00751, IPR001275, SM00301): DM DNA binding domain FAA_hydrolase_N (PF09298, IPR015377): Fumarylacetoacetase N-terminal DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger RUN (PF02759, IPR004012, SM00593): RUN domain Tektin (PF03148, IPR000435): Tektin family |
50 |
SIAH1 | suppressor | 10 | 0.611 | 7.633 | Sina (PF03145, IPR018121): Seven in absentia protein family |
51 |
SIAH2 | oncoprotein | 8 | 0.667 | 4.250 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
52 |
SMAD3 | oncoprotein | 17 | 0.358 | 41.779 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
53 |
SMAD4 | suppressor | 10 | 0.722 | 3.163 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
54 |
SREBF2 | protein found in more fusions | 6 | 0.600 | 1.021 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
55 |
STAT4 | interactor | 2 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
56 |
SUMO1 | interactor | 15 | 0.462 | 25.239 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
57 |
SUMO1P1 | interactor | 7 | 0.600 | 4.333 | NA |
58 |
SUMO2 | interactor | 9 | 0.571 | 6.286 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
59 |
SUMO3 | interactor | 4 | 1.000 | 0 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
60 |
TICAM2 | interactor | 1 | 0 | 0 | TIR_2 (PF13676, IPR000157): TIR domain |
61 |
TP53 | suppressor | 22 | 0.329 | 83.456 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
62 |
TRAF2 | interactor | 8 | 0.333 | 12.167 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
63 |
TRIM23 | interactor | 6 | 0.800 | 1.167 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family FemAB (PF02388, IPR003447): FemAB family zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
64 |
TRIM27 | oncoprotein | 12 | 0.455 | 22.386 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
65 |
TRIM55 | interactor | 6 | 0.900 | 0.500 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein NABP (PF07990, IPR012940): Nucleic acid binding protein NABP zf-HIT (PF04438, IPR007529): HIT zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
66 |
TRIM63 | interactor | 6 | 0.900 | 0.500 | DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) KIP1 (PF07765, IPR011684): KIP1-like protein RED_C (PF07807, IPR012492): RED-like protein C-terminal region zf-HIT (PF04438, IPR007529): HIT zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module' |
67 |
TSR2 | interactor | 1 | 0 | 0 | WGG (PF10273, IPR019398): Pre-rRNA-processing protein TSR2 |
68 |
UBE2I | interactor | 41 | 0.167 | 497.035 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
69 |
ZBED1 | interactor | 4 | 1.000 | 0 | Dimer_Tnp_hAT (PF05699, IPR008906): hAT family C-terminal dimerisation region zf-BED (PF02892, IPR003656, SM00614): BED zinc finger DUF4413 (PF14372, IPR025525): Domain of unknown function (DUF4413) |
70 |
ZBTB8A | interactor | 5 | 0.667 | 1.333 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
71 |
ZNF451 | protein found in more fusions | 7 | 0.800 | 0.956 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type EPL1 (PF10513, IPR019542): Enhancer of polycomb-like zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger Cys_rich_KTR (PF14205, IPR025957): Cysteine-rich KTR FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |