1 |
PIAS1 | parental protein | 98 | 0.080 | 5869.835 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
2 |
AKT1 | oncoprotein | 17 | 0.358 | 32.571 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
3 |
AR | oncoprotein | 22 | 0.329 | 83.818 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
4 |
ATXN1 | protein found in more fusions | 9 | 0.536 | 8.875 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term |
5 |
ATXN7 | interactor | 6 | 0.667 | 1.505 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain Macoilin (PF09726, IPR019130): Transmembrane protein DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505) IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
6 |
BARD1 | oncoprotein | 10 | 0.556 | 9.450 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
7 |
BRCA1 | oncoprotein | 23 | 0.329 | 85.837 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
8 |
CASP8AP2 | interactor | 9 | 0.571 | 5.800 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) IncA (PF04156, IPR007285): IncA protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
9 |
CBS | protein found in more fusions | 3 | 1.000 | 0 | CBS (PF00571, IPR000644, SM00116): CBS domain DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414) PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme |
10 |
CEBPA | oncoprotein | 8 | 0.619 | 3.654 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
11 |
CEBPE | interactor | 6 | 0.700 | 1.667 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
12 |
CEP250 | interactor | 2 | 1.000 | 0 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
13 |
CHUK | suppressor | 12 | 0.564 | 8.619 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
14 |
CREB1 | oncoprotein | 16 | 0.381 | 37.383 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
15 |
CSNK2A1 | oncoprotein | 14 | 0.397 | 22.934 | Pkinase (PF00069, IPR000719): Protein kinase domain |
16 |
CSRP2 | interactor | 3 | 0.667 | 0.500 | LIM (PF00412, IPR001781, SM00132): LIM domain |
17 |
DCLRE1A | interactor | 1 | 0 | 0 | DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase Glyco_hydro_45 (PF02015, IPR000334): Glycosyl hydrolase family 45 Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain |
18 |
DDX5 | oncoprotein | 10 | 0.556 | 10.567 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
19 |
DNM1 | interactor | 4 | 1.000 | 0 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
20 |
DNMT3A | oncoprotein | 4 | 0.833 | 0.500 | DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain |
21 |
DNMT3B | suppressor | 5 | 0.700 | 1.452 | DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain |
22 |
ERP44 | interactor | 3 | 0.667 | 1.000 | Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
23 |
ESR1 | oncoprotein | 27 | 0.280 | 138.482 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
24 |
FLI1 | oncoprotein | 5 | 0.800 | 0.700 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
25 |
FOXA1 | oncoprotein | 4 | 0.500 | 1.182 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region HNF_C (PF09354, IPR018533): HNF3 C-terminal domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
26 |
FRAT1 | oncoprotein | 2 | 1.000 | 0 | GSK-3_bind (PF05350, IPR008014): Glycogen synthase kinase-3 binding |
27 |
GLUL | protein found in more fusions | 7 | 0.600 | 2.686 | Gln-synt_C (PF00120, IPR008146): Glutamine synthetase, catalytic domain Gln-synt_N (PF03951, IPR008147): Glutamine synthetase, beta-Grasp domain |
28 |
GSK3B | oncoprotein | 14 | 0.449 | 24.522 | Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
HECTD2 | interactor | 1 | 0 | 0 | HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
30 |
HIC1 | oncoprotein | 4 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
31 |
HIF1A | suppressor | 7 | 0.905 | 0.315 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
32 |
HTT | protein found in more fusions | 11 | 0.422 | 14.276 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
33 |
ID1 | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
34 |
JUN | oncoprotein | 22 | 0.381 | 60.510 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
35 |
KLC1 | interactor | 2 | 1.000 | 0 | Gly_radical (PF01228, IPR001150): Glycine radical SOGA (PF11365, IPR027881): Protein SOGA TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
36 |
L3MBTL2 | interactor | 2 | 1.000 | 0 | MBT (PF02820, IPR004092, SM00561): mbt repeat |
37 |
MAML1 | interactor | 1 | 0 | 0 | MamL-1 (PF09596, IPR019082): MamL-1 domain Kri1 (PF05178, IPR018034): KRI1-like family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
38 |
MBD1 | interactor | 4 | 0.500 | 1.400 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain |
39 |
MDC1 | oncoprotein | 13 | 0.410 | 28.034 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
40 |
MDM2 | oncoprotein | 20 | 0.404 | 46.977 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
41 |
MITF | oncoprotein | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
42 |
MX1 | interactor | 6 | 0.800 | 0.786 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
43 |
MYB | oncoprotein | 8 | 0.607 | 5.322 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
44 |
NCOA3 | oncoprotein | 14 | 0.374 | 31.545 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
45 |
NCOR1 | oncoprotein | 25 | 0.290 | 130.694 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
46 |
NFATC1 | oncoprotein | 6 | 0.867 | 0.419 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
47 |
NR1H2 | oncoprotein | 5 | 0.600 | 1.700 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
48 |
NR1H3 | interactor | 4 | 0.667 | 0.800 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
49 |
PAXIP1 | interactor | 8 | 0.357 | 9.067 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
50 |
PIAS2 | protein found in more fusions | 28 | 0.225 | 178.888 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
51 |
PLAG1 | oncoprotein | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
52 |
PML | oncoprotein | 26 | 0.303 | 110.995 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
53 |
POLK | interactor | 1 | 0 | 0 | ATP-cone (PF03477, IPR005144): ATP cone domain IMS (PF00817, IPR001126): impB/mucB/samB family IMS_HHH (PF11798, IPR024728): IMS family HHH motif IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain |
54 |
PPARG | oncoprotein | 13 | 0.409 | 22.163 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
55 |
PPARGC1A | interactor | 7 | 0.667 | 2.094 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
56 |
PPARGC1B | interactor | 4 | 0.500 | 1.050 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein Mak16 (PF04874, IPR006958): Mak16 protein C-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus |
57 |
PPP1CA | oncoprotein | 14 | 0.560 | 14.733 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
58 |
PPP1CC | oncoprotein | 9 | 0.500 | 9.567 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
59 |
PRDM1 | oncoprotein | 3 | 1.000 | 0 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
60 |
PRPF40A | protein found in more fusions | 12 | 0.291 | 27.239 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
61 |
PSME3 | protein found in more fusions | 9 | 0.536 | 9.219 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
62 |
PTK2 | protein found in more fusions | 8 | 0.571 | 7.067 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
63 |
RAD54L2 | interactor | 8 | 0.500 | 5.271 | SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase |
64 |
RBBP6 | oncoprotein | 6 | 0.800 | 1.567 | DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936) DWNN (PF08783, IPR014891): DWNN domain Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region U-box (PF04564, IPR003613, SM00504): U-box domain SBF2 (PF12335, IPR022096): Myotubularin protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
65 |
SAFB | suppressor | 6 | 0.667 | 2.622 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
66 |
SATB1 | oncoprotein | 6 | 0.733 | 3.000 | CUT (PF02376, IPR003350, SM01109): CUT domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
67 |
SERBP1 | interactor | 6 | 0.800 | 0.472 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
68 |
SGTA | interactor | 1 | 0 | 0 | TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_17 (PF13431): Tetratricopeptide repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA |
69 |
SHFM1 | interactor | 5 | 0.800 | 0.900 | CLLAC (PF15675, IPR031379): CLLAC-motif containing domain |
70 |
SIAH1 | suppressor | 13 | 0.424 | 22.108 | Sina (PF03145, IPR018121): Seven in absentia protein family |
71 |
SIAH2 | oncoprotein | 8 | 0.667 | 3.217 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
72 |
SKIL | oncoprotein | 9 | 0.571 | 5.858 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
73 |
SMAD1 | interactor | 9 | 0.500 | 9.950 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
74 |
SMAD4 | oncoprotein | 14 | 0.449 | 22.372 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
75 |
SMAD7 | interactor | 5 | 0.700 | 0.783 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
76 |
SOX2 | oncoprotein | 5 | 0.667 | 0.722 | HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor |
77 |
SP3 | interactor | 4 | 1.000 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
78 |
SPOP | oncoprotein | 5 | 0.833 | 0.154 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain MATH (PF00917, IPR002083, SM00061): MATH domain |
79 |
SREBF2 | protein found in more fusions | 7 | 0.600 | 2.538 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
80 |
SRSF1 | protein found in more fusions | 12 | 0.527 | 14.183 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
81 |
STAB2 | interactor | 1 | 0 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Fasciclin (PF02469, IPR000782, SM00554): Fasciclin domain Xlink (PF00193, IPR000538, SM00445): Extracellular link domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
82 |
STAT1 | suppressor | 9 | 0.536 | 8.150 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
83 |
SUMO1 | interactor | 23 | 0.260 | 105.358 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
84 |
SUMO2 | interactor | 14 | 0.372 | 27.088 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
85 |
SUMO3 | interactor | 4 | 1.000 | 0 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
86 |
TERF2 | interactor | 6 | 0.700 | 1.400 | Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif |
87 |
TP53 | oncoprotein | 38 | 0.231 | 319.852 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
88 |
TRIM27 | oncoprotein | 12 | 0.509 | 16.438 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
89 |
TRIM5 | interactor | 3 | 1.000 | 0 | Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0) Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
90 |
TRIM55 | interactor | 8 | 0.571 | 5.067 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein NABP (PF07990, IPR012940): Nucleic acid binding protein NABP zf-HIT (PF04438, IPR007529): HIT zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
91 |
TRIM63 | interactor | 6 | 0.900 | 0.500 | DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) KIP1 (PF07765, IPR011684): KIP1-like protein RED_C (PF07807, IPR012492): RED-like protein C-terminal region zf-HIT (PF04438, IPR007529): HIT zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module' |
92 |
UBE2I | interactor | 55 | 0.156 | 887.542 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
93 |
VPS16 | interactor | 3 | 0.667 | 1.000 | Vps16_C (PF04840, IPR006925): Vps16, C-terminal region Vps16_N (PF04841, IPR006926): Vps16, N-terminal region |
94 |
YWHAZ | protein found in more fusions | 11 | 0.400 | 21.315 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
95 |
ZMIZ2 | interactor | 3 | 1.000 | 0 | zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger |
96 |
ZMYND11 | suppressor | 7 | 0.800 | 1.400 | DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
97 |
ZNF451 | protein found in more fusions | 10 | 0.528 | 6.775 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type EPL1 (PF10513, IPR019542): Enhancer of polycomb-like zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger Cys_rich_KTR (PF14205, IPR025957): Cysteine-rich KTR FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
98 |
ZNF76 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type CopK (PF11525, IPR021604): Copper resistance protein K DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain DUF4376 (PF14301, IPR025484): Domain of unknown function (DUF4376) |