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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PHYHIPL (from a repository: Thu Nov 10 14:59:26 2016)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins2 (16.67 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)21 (31.82 %)
The number (and %) of affected PPIs12 (57.14 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.667
Assortativity coefficient-0.3655
The network average Clustering coefficient0.410
The number (and %) of a zero Clustering coefficients5 (41.67 %)
The number (and %) of a zero Betweenness Centrality8 (66.67 %)


List of the fusions

Proteins found in more fusions HSPB1 (see 2 fusions); OPA3 (see 2 fusions); PHYHIPL (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PHYHIPLparental protein120.09195.000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
2 ACOT7interactor1004HBT (PF03061, IPR006683): Thioesterase superfamily
NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
3 C1QBPinteractor21.0000MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
4 DHRS4interactor40.6671.000adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
5 ECH1interactor30.6671.000ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
6 HSPB1oncoprotein200HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
7 LOC102724023interactor100DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
8 OPA3protein found in more fusions50.5003.000IL11 (PF07400, IPR020438): Interleukin 11
OPA3 (PF07047, IPR010754): Optic atrophy 3 protein (OPA3)
9 PDE9Ainteractor200PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
10 PMPCBinteractor21.0000Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
11 STARD7interactor21.0000START (PF01852, IPR002913, SM00234): START domain
12 TMCO6interactor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
KorB (PF08535, IPR013741): KorB domain
HEAT_EZ (PF13513): HEAT-like repeat

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