Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins PABPC1 (from a repository: Sat Dec 3 14:16:12 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 226 The number (and %) of the onco-proteins 66 (29.20 %) The number (and %) of the tumor suppressors 25 (11.06 %) Total number of binary PPIs (saturation %) 3772 (14.84 %) The number (and %) of affected PPIs 226 (5.99 %) The number of possible different fusions 51 PPI diameter 2 PPI radius 1 The average degree of PPI 32.584 Assortativity coefficient -0.1342 The network average Clustering coefficient 0.501 The number (and %) of a zero Clustering coefficients 1 (0.44 %) The number (and %) of a zero Betweenness Centrality 8 (3.54 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: PABPC1	All fusions : AW880952;
Proteins found in more fusions	EEF1G (see 1 fusions); U2AF2 (see 2 fusions); RPL37A/PRPF8 (see 1 fusions); CUL1 (see 3 fusions); UBA1 (see 2 fusions); GAN (see 1 fusions); HDAC5 (see 1 fusions); RPA1 (see 1 fusions); RPLP2 (see 1 fusions); PRPF3 (see 1 fusions); SNW1 (see 1 fusions); ZMYND11 (see 1 fusions); CUL4A (see 4 fusions); RPL27/RPS6 (see 1 fusions); SRPK2 (see 1 fusions); HNRNPD (see 1 fusions); SNRNP200 (see 3 fusions); ACAT2 (see 1 fusions); PRPF8 (see 3 fusions); BAG3 (see 4 fusions); ATP5A1 (see 1 fusions); NCL (see 3 fusions); STAU1 (see 2 fusions); EEF1A1 (see 1 fusions); NTRK1/RPL7A (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); SKI (see 1 fusions); SMG6 (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); FN1/YWHAG (see 1 fusions); TP53 (see 3 fusions); SREK1 (see 4 fusions); G3BP1 (see 1 fusions); YWHAG (see 1 fusions); LUC7L2 (see 2 fusions); PUF60 (see 2 fusions); PABPC1 (see 2 fusions); PDCD6 (see 1 fusions); SERBP1 (see 1 fusions); PCBP2 (see 3 fusions); EIF4A2 (see 2 fusions); SH3KBP1 (see 1 fusions); MCM2 (see 1 fusions); UBR5 (see 4 fusions); RACK1 (see 3 fusions); USP10 (see 1 fusions); FN1/RPL6 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	PABPC1	parental protein	226	0.137	19773.139	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
2	ACAT2	protein found in more fusions	6	0.700	1.221	Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
3	AGO1	interactor	12	0.500	16.789	ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
4	AGO2	interactor	23	0.403	60.972	ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5	AIRE	interactor	7	0.667	0.971	PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
6	ALYREF	interactor	36	0.345	64.936	FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
7	ANAPC5	interactor	4	0.500	1.536	TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
8	APBB1	interactor	9	0.607	1.616	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
9	APEX1	interactor	10	0.578	2.774	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
10	ARRB2	interactor	44	0.413	110.631	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
11	ATP5A1	protein found in more fusions	32	0.385	62.401	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
12	ATP6V1B2	interactor	10	0.422	5.876	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
13	ATXN2	interactor	10	0.578	7.308	LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Spt20 (PF12090, IPR021950): Spt20 family SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
14	ATXN2L	interactor	11	0.473	7.204	LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
15	BAG3	oncoprotein	21	0.195	68.686	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
16	BCAR3	oncoprotein	1	0	0	RasGEF (PF00617, IPR001895, SM00147): RasGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain
17	BRCA1	suppressor	26	0.263	104.338	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
18	BRIX1	interactor	22	0.827	2.220	Brix (PF04427, IPR007109, SM00879): Brix domain
19	CAND1	interactor	95	0.367	564.539	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
20	CCDC8	interactor	52	0.391	165.472	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
21	CD81	interactor	41	0.426	66.505	Tetraspannin (PF00335, IPR018499): Tetraspanin family
22	CEP250	interactor	44	0.469	139.275	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
23	CHAF1A	interactor	9	0.250	13.317	CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
24	CLK2	interactor	9	0.500	6.533	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Pkinase (PF00069, IPR000719): Protein kinase domain zf-met (PF12874): Zinc-finger of C2H2 type
25	CLK3	interactor	7	0.667	1.387	Pkinase (PF00069, IPR000719): Protein kinase domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
26	CNOT6	interactor	8	0.571	6.287	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
27	CNOT7	interactor	14	0.385	32.660	CAF1 (PF04857, IPR006941): CAF1 family ribonuclease
28	COPS5	protein found in more fusions	84	0.387	409.235	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
29	COPS6	interactor	31	0.618	22.795	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
30	CRY1	interactor	18	0.353	16.302	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
31	CSF2	suppressor	5	1.000	0	GM_CSF (PF01109, IPR000773, SM00040): Granulocyte-macrophage colony-stimulating factor
32	CSTF2	interactor	12	0.318	22.976	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
33	CSTF3	interactor	11	0.491	11.276	NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
34	CUL1	suppressor	86	0.353	546.560	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
35	CUL2	suppressor	60	0.446	160.251	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
36	CUL3	protein found in more fusions	110	0.282	1215.849	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
37	CUL4A	protein found in more fusions	28	0.618	34.156	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38	CUL4B	oncoprotein	50	0.516	103.512	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
39	CUL5	suppressor	59	0.503	113.275	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
40	CUL7	protein found in more fusions	76	0.320	421.497	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
41	DCUN1D1	interactor	33	0.674	19.086	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
42	DDX19A	interactor	6	0.600	1.930	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
43	DDX39A	interactor	11	0.467	7.844	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
44	DDX39B	interactor	23	0.316	48.611	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45	DHX15	interactor	50	0.318	227.851	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
46	DYNLL1	interactor	11	0.533	7.860	Dynein_light (PF01221, IPR001372): Dynein light chain type 1
47	EEF1A1	suppressor	74	0.424	317.780	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
48	EEF1A2	oncoprotein	24	0.467	19.572	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
49	EEF1G	protein found in more fusions	30	0.429	40.144	EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
50	EEF2	interactor	47	0.512	129.965	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
51	EIF4A1	interactor	34	0.337	100.745	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
52	EIF4A2	oncoprotein	15	0.385	22.611	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
53	EIF4B	interactor	23	0.255	72.295	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3774 (PF12609, IPR022251): Wound-induced protein PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
54	EIF4E	oncoprotein	8	0.679	4.198	IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
55	EIF4G1	oncoprotein	25	0.367	62.129	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) MA3 (PF02847, IPR003891, SM00544): MA3 domain MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
56	EIF4G3	interactor	10	0.600	5.109	MA3 (PF02847, IPR003891, SM00544): MA3 domain MIF4G (PF02854, IPR003890, SM00543): MIF4G domain W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
57	ELAVL1	oncoprotein	71	0.217	939.354	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
58	ESR1	suppressor	67	0.383	332.996	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
59	ETF1	interactor	6	0.667	2.467	eRF1_1 (PF03463, IPR005140): eRF1 domain 1 eRF1_2 (PF03464, IPR005141): eRF1 domain 2 eRF1_3 (PF03465, IPR005142): eRF1 domain 3
60	FBXO6	interactor	40	0.346	104.876	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
61	FBXW11	interactor	26	0.347	70.560	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
62	FDPS	interactor	5	0.900	0.118	polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
63	FN1	oncoprotein	77	0.352	354.792	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
64	G3BP1	protein found in more fusions	31	0.467	45.863	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
65	G3BP2	interactor	20	0.542	17.384	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
66	GAN	protein found in more fusions	21	0.584	11.397	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif
67	GIGYF2	interactor	17	0.441	23.398	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
68	GNPDA1	interactor	2	1.000	0	Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
69	GSPT1	oncoprotein	14	0.516	18.265	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
70	GSPT2	interactor	6	0.733	1.917	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
71	H2AFX	suppressor	23	0.391	33.285	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
72	HAUS1	interactor	8	0.476	4.681	THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
73	HBB	interactor	7	0.429	4.579	Globin (PF00042, IPR000971): Globin
74	HDAC5	protein found in more fusions	43	0.377	89.491	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
75	HIST1H3E	interactor	28	0.347	91.007	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
76	HNRNPA1	interactor	89	0.312	875.724	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
77	HNRNPD	oncoprotein	61	0.326	322.017	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
78	HNRNPK	oncoprotein	65	0.353	344.378	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
79	HNRNPR	interactor	52	0.447	101.608	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
80	HNRNPU	interactor	93	0.395	571.493	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
81	HSPA8	oncoprotein	50	0.362	215.394	HSP70 (PF00012, IPR013126): Hsp70 protein
82	ICAM1	oncoprotein	32	0.603	18.207	Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
83	IFIT1	interactor	6	0.733	0.638	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat DUF4268 (PF14088, IPR025364): Domain of unknown function (DUF4268) TPR_19 (PF14559): Tetratricopeptide repeat
84	IFIT2	interactor	8	0.643	2.037	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
85	IFIT3	interactor	13	0.455	18.716	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
86	IGBP1	interactor	12	0.242	26.797	TAP42 (PF04177, IPR007304): TAP42-like family
87	IGSF8	oncoprotein	38	0.516	36.775	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
88	IKBKE	interactor	4	0.667	0.333	IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
89	IL7R	interactor	23	0.391	19.031	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
90	ILF3	oncoprotein	72	0.467	308.445	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain
91	ITCH	interactor	11	0.422	7.072	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
92	ITGA4	interactor	64	0.377	267.173	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
93	KIN	interactor	3	1.000	0	KOW (PF00467, IPR005824, SM00739): KOW motif SecM (PF06558, IPR009502): Secretion monitor precursor protein (SecM) Kin17_mid (PF10357, IPR019447): Domain of Kin17 curved DNA-binding protein zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
94	LUC7L2	protein found in more fusions	34	0.369	129.561	LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
95	MAEL	interactor	7	0.524	2.117	HMG_box_2 (PF09011, IPR009071): HMG-box domain Maelstrom (PF13017, IPR024970): piRNA pathway germ-plasm component
96	MAPKAPK2	oncoprotein	8	0.667	2.195	Pkinase (PF00069, IPR000719): Protein kinase domain
97	MCM2	oncoprotein	84	0.351	573.986	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
98	MEX3A	interactor	2	1.000	0	KH_1 (PF00013, IPR004088, SM00322): KH domain MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
99	MEX3B	interactor	3	0.667	0.400	KH_1 (PF00013, IPR004088, SM00322): KH domain DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
100	MEX3C	interactor	10	0.378	9.124	KH_1 (PF00013, IPR004088, SM00322): KH domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
101	MIF	oncoprotein	12	0.582	4.018	MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
102	MKRN1	interactor	5	0.700	1.487	Opy2 (PF09463, IPR018571): Opy2 protein zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) CD52 (PF15116, IPR026643): CAMPATH-1 antigen MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal Torus (PF16131, IPR032297): Torus domain zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
103	MSI2	oncoprotein	11	0.564	3.498	NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
104	NCL	protein found in more fusions	70	0.410	350.929	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
105	NDRG1	suppressor	19	0.468	25.201	Ndr (PF03096, IPR004142): Ndr family
106	NEDD8	interactor	40	0.574	62.212	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107	NFX1	interactor	12	0.697	2.209	R3H (PF01424, IPR001374, SM00393): R3H domain XPG_I (PF00867, IPR006086, SM00484): XPG I-region zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
108	NTRK1	oncoprotein	111	0.232	1831.872	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
109	OBSL1	interactor	65	0.333	267.494	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
110	ORC4	interactor	5	0.500	0.452	AAA_16 (PF13191): AAA ATPase domain ORC4_C (PF14629, IPR032705): Origin recognition complex (ORC) subunit 4 C-terminus
111	P4HB	interactor	25	0.337	47.694	Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
112	PAIP1	interactor	11	0.473	14.360	MIF4G (PF02854, IPR003890, SM00543): MIF4G domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
113	PAIP2	suppressor	8	0.393	7.308	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
114	PAIP2B	interactor	3	0.667	0.100	OB_RNB (PF08206, IPR013223): Ribonuclease B OB domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
115	PAN2	interactor	56	0.375	346.827	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
116	PAN3	interactor	7	0.524	3.544	Pkinase (PF00069, IPR000719): Protein kinase domain zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
117	PAPOLA	interactor	7	0.667	1.959	PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein
118	PAPOLB	interactor	3	1.000	0	PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
119	PCBP1	oncoprotein	40	0.360	141.804	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
120	PCBP2	protein found in more fusions	35	0.406	75.525	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
121	PDCD6	oncoprotein	20	0.409	26.153	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
122	PFAS	interactor	7	0.333	5.465	AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
123	PHGDH	interactor	20	0.579	6.566	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
124	PIN1	suppressor	18	0.392	22.127	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
125	PINX1	suppressor	7	0.476	4.199	G-patch (PF01585, IPR000467, SM00443): G-patch domain NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat
126	PLRG1	interactor	9	0.778	1.373	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
127	POLE	interactor	6	0.600	1.208	DNA_pol_B (PF00136, IPR006134): DNA polymerase family B DNA_pol_B_exo1 (PF03104, IPR006133): DNA polymerase family B, exonuclease domain DUF1744 (PF08490, IPR013697, SM01159): Domain of unknown function (DUF1744) DNA_pol_B_exo2 (PF10108, IPR019288): Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-RRPl_C4 (PF17026, IPR031502): Putative ribonucleoprotein zinc-finger pf C4 type
128	PPP2CA	suppressor	20	0.247	55.409	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
129	PREP	interactor	4	0.500	0.390	Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family Peptidase_S9_N (PF02897, IPR023302): Prolyl oligopeptidase, N-terminal beta-propeller domain
130	PRMT6	interactor	2	1.000	0	Methyltransf_25 (PF13649): Methyltransferase domain
131	PRPF3	protein found in more fusions	19	0.425	25.533	DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3) PWI (PF01480, IPR002483, SM00311): PWI domain TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
132	PRPF8	oncoprotein	47	0.360	159.068	PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
133	PSMD9	interactor	8	0.429	9.564	Remorin_C (PF03763, IPR005516): Remorin, C-terminal region DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046) PDZ_2 (PF13180, IPR001478): PDZ domain
134	PUF60	protein found in more fusions	23	0.550	19.246	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
135	PXN	oncoprotein	6	0.733	1.200	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
136	R3HCC1L	interactor	2	1.000	0	NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561
137	RACK1	suppressor	51	0.509	114.358	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
138	RAE1	interactor	17	0.412	19.854	Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
139	RALY	interactor	23	0.696	7.790	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
140	RBM4	suppressor	25	0.540	14.010	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN
141	RBM8A	interactor	22	0.233	85.764	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
142	RPA1	suppressor	52	0.420	210.387	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
143	RPA2	oncoprotein	44	0.451	119.518	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
144	RPA3	interactor	39	0.492	51.290	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
145	RPL10	suppressor	59	0.608	148.412	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
146	RPL10A	interactor	58	0.702	39.070	Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
147	RPL11	suppressor	67	0.601	136.512	Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
148	RPL13	interactor	60	0.646	65.060	Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
149	RPL13A	interactor	51	0.712	34.980	Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
150	RPL14	interactor	59	0.660	57.805	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
151	RPL15	interactor	67	0.604	92.855	Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
152	RPL17	interactor	49	0.745	29.097	Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
153	RPL18	interactor	72	0.569	115.335	Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
154	RPL18A	interactor	53	0.688	41.537	Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
155	RPL27	protein found in more fusions	47	0.769	21.712	Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
156	RPL27A	interactor	51	0.707	39.426	Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
157	RPL3	interactor	60	0.655	76.432	Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
158	RPL35	interactor	50	0.712	32.965	Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein XFP_N (PF09364, IPR018970): XFP N-terminal domain
159	RPL37A	protein found in more fusions	48	0.702	54.580	Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
160	RPL39	interactor	5	0.800	0.222	Ribosomal_L39 (PF00832, IPR000077): Ribosomal L39 protein
161	RPL4	interactor	77	0.513	240.958	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
162	RPL5	suppressor	69	0.615	84.018	Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
163	RPL6	protein found in more fusions	77	0.515	189.804	Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
164	RPL7	interactor	67	0.624	75.388	Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
165	RPL7A	protein found in more fusions	66	0.588	101.885	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
166	RPLP0	interactor	71	0.563	118.156	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
167	RPLP2	protein found in more fusions	57	0.629	66.619	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
168	RPS16	interactor	64	0.623	113.804	Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
169	RPS21	interactor	41	0.752	25.727	Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
170	RPS28	interactor	41	0.657	45.162	Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
171	RPS3A	interactor	75	0.559	181.686	Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
172	RPS4X	interactor	75	0.548	171.966	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
173	RPS6	protein found in more fusions	72	0.577	143.571	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
174	RPS8	interactor	72	0.586	100.184	Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
175	RPSA	interactor	65	0.528	220.548	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
176	RUVBL1	oncoprotein	30	0.372	74.795	TIP49 (PF06068, IPR010339): TIP49 C-terminus
177	SART1	interactor	30	0.490	41.663	SART-1 (PF03343, IPR005011): SART-1 family Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
178	SERBP1	protein found in more fusions	28	0.450	42.092	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
179	SF3A1	interactor	33	0.439	79.505	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
180	SFN	suppressor	39	0.421	100.852	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
181	SGTA	interactor	5	0.600	1.549	TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_17 (PF13431): Tetratricopeptide repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
182	SH3KBP1	protein found in more fusions	12	0.255	20.864	Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain
183	SIRT7	interactor	55	0.325	268.900	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
184	SKI	oncoprotein	16	0.629	4.948	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
185	SKIV2L2	interactor	18	0.516	15.683	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
186	SMAD3	oncoprotein	23	0.312	69.377	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
187	SMG1	interactor	9	0.679	3.040	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein XhlA (PF10779, IPR019715): Haemolysin XhlA PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
188	SMG6	oncoprotein	6	0.700	2.333	EST1 (PF10374, IPR019458): Telomerase activating protein Est1 EST1_DNA_bind (PF10373, IPR018834): Est1 DNA/RNA binding domain PIN_4 (PF13638, IPR002716): PIN domain
189	SNRNP200	protein found in more fusions	40	0.449	67.430	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
190	SNRPA	interactor	29	0.418	61.241	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
191	SNRPD3	interactor	40	0.283	156.039	LSM (PF01423, IPR001163): LSM domain
192	SNU13	interactor	31	0.641	21.245	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
193	SNW1	protein found in more fusions	56	0.329	330.556	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
194	SREK1	protein found in more fusions	17	0.542	7.391	Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
195	SRPK1	interactor	26	0.495	37.233	FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pkinase (PF00069, IPR000719): Protein kinase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
196	SRPK2	oncoprotein	31	0.347	101.063	DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
197	STAU1	protein found in more fusions	55	0.513	76.545	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
198	SUMO1	interactor	8	0.619	3.843	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
199	SYNCRIP	interactor	57	0.371	201.512	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
200	TARDBP	interactor	80	0.367	445.645	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
201	TDRD3	interactor	7	0.429	3.938	RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein TUDOR (PF00567, IPR002999, SM00333): Tudor domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472)
202	TERT	oncoprotein	10	0.289	20.745	RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
203	TMOD3	interactor	11	0.364	11.337	Tropomodulin (PF03250, IPR004934): Tropomodulin Usher (PF00577, IPR000015): Outer membrane usher protein LRR_6 (PF13516, IPR001611): Leucine Rich repeat
204	TNRC6A	interactor	10	0.444	11.002	CreD (PF06123, IPR010364): Inner membrane protein CreD RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Ago_hook (PF10427, IPR019486): Argonaute hook M_domain (PF12938, IPR026805): M domain of GW182 TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
205	TNRC6B	interactor	15	0.448	30.707	DUF1421 (PF07223, IPR010820): Protein of unknown function (DUF1421) Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Ago_hook (PF10427, IPR019486): Argonaute hook DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain RRM_occluded (PF16842, IPR031766): Occluded RNA-recognition motif
206	TNRC6C	interactor	11	0.455	10.150	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Ago_hook (PF10427, IPR019486): Argonaute hook DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) M_domain (PF12938, IPR026805): M domain of GW182 DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
207	TOB1	interactor	7	0.381	5.466	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region BTG (PF07742, IPR002087, SM00099): BTG family PRIMA1 (PF16101): Proline-rich membrane anchor 1
208	TOB2	oncoprotein	7	0.524	3.958	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region BTG (PF07742, IPR002087, SM00099): BTG family
209	TP53	suppressor	79	0.282	810.451	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
210	TSG101	suppressor	11	0.444	12.259	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain
211	U2AF1	oncoprotein	26	0.551	31.773	DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
212	U2AF2	protein found in more fusions	63	0.374	259.423	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
213	UAP1	interactor	4	0.667	0.065	UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
214	UBA1	protein found in more fusions	15	0.319	13.394	ThiF (PF00899, IPR000594): ThiF family E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
215	UBL4A	interactor	46	0.550	75.342	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
216	UBR5	protein found in more fusions	21	0.247	81.317	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
217	UPF1	interactor	37	0.396	168.721	UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain
218	USP10	protein found in more fusions	10	0.722	2.357	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
219	VCAM1	interactor	63	0.375	194.889	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
220	WBP4	interactor	8	0.679	1.417	CDC45 (PF02724, IPR003874): CDC45-like protein WW (PF00397, IPR001202, SM00456): WW domain zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger TMCO5 (PF14992, IPR026617): TMCO5 family
221	WWOX	suppressor	22	0.325	51.442	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain
222	WWP2	interactor	6	0.600	1.702	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
223	XPO1	interactor	65	0.223	842.441	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
224	YWHAG	protein found in more fusions	31	0.287	132.574	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
225	ZFP36	suppressor	6	0.400	3.228	zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
226	ZMYND11	suppressor	9	0.464	2.461	DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain

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