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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)114
The number (and %) of the onco-proteins27 (23.68 %)
The number (and %) of the tumor suppressors17 (14.91 %)
Total number of binary PPIs (saturation %)660 (10.25 %)
The number (and %) of affected PPIs114 (17.27 %)
The number of possible different fusions20
PPI diameter2
PPI radius1
The average degree of PPI10.684
Assortativity coefficient-0.2821
The network average Clustering coefficient0.500
The number (and %) of a zero Clustering coefficients13 (11.40 %)
The number (and %) of a zero Betweenness Centrality29 (25.44 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NUDT21 All fusions
: DB476730; DB481810;
Proteins found in more fusions EEF1G (see 1 fusions); STAU1 (see 2 fusions); NPM1 (see 1 fusions); CUL7 (see 2 fusions); HUWE1 (see 2 fusions); CUL3 (see 1 fusions); ATXN1 (see 3 fusions); A2M (see 2 fusions); SRPK2 (see 1 fusions); FAF1 (see 2 fusions); IKZF1 (see 1 fusions); SNCAIP (see 1 fusions); SHC1 (see 1 fusions); EZH2 (see 1 fusions); NUDT21 (see 2 fusions); S100A13 (see 1 fusions); RPA1 (see 1 fusions); NEDD4 (see 1 fusions); F13A1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NUDT21parental protein1140.0788726.652NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
2 A2Mprotein found in more fusions200A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
3 ASB12interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
SOCS_box (PF07525, IPR001496): SOCS box
4 ATXN1protein found in more fusions31.0000AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
5 CAND1interactor230.48536.895Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
6 CARM1oncoprotein60.8670.800K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
7 CD2BP2interactor40.6672.000GYF (PF02213, IPR003169, SM00444): GYF domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
8 CD81interactor100.5568.263Tetraspannin (PF00335, IPR018499): Tetraspanin family
9 CDC5Linteractor290.354110.783OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
10 CEP126interactor30.6670.500Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy
11 CLP1oncoprotein40.8330.250Clp1 (PF06807, IPR010655): Pre-mRNA cleavage complex II protein Clp1
CLP1_N (PF16573, IPR032324): N-terminal beta-sandwich domain of polyadenylation factor
CLP1_P (PF16575, IPR032319): mRNA cleavage and polyadenylation factor CLP1 P-loop
12 CPSF6interactor260.302123.298RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
13 CPSF7interactor230.31282.278CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
14 CRTAPinteractor31.0000Whi5 (PF08528, IPR013734): Whi5 like
YfiO (PF13525): Outer membrane lipoprotein
Stomagen (PF16851, IPR031753): Stomagen
15 CTNND2oncoprotein100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
16 CUL3protein found in more fusions390.242330.519Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
17 CUL7protein found in more fusions220.38646.185ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
18 DBN1oncoprotein50.5000.840Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
19 DLDinteractor50.7000.639Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
20 DNMT3Linteractor31.0000CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
21 DYNC1I1interactor40.6671.333CDC45 (PF02724, IPR003874): CDC45-like protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2
AviRa (PF11599, IPR024268): RRNA methyltransferase AviRa
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
22 EEDsuppressor240.28974.335WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
23 EEF1Gprotein found in more fusions170.44223.559EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
24 EEFSECinteractor30.6670.667RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
25 EIF3Aoncoprotein190.28755.158DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
26 EIF3CLinteractor50.8000.583eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399, IPR000717, SM00088): PCI domain
27 EIF4Hinteractor60.6670.906eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
28 ESR1suppressor260.243136.640Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
29 EXOSC6interactor50.8330.143RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
30 EZH2suppressor180.29450.779CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
31 F13A1protein found in more fusions31.0000Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
32 FAF1protein found in more fusions80.5246.233UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
33 FBN3interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
34 FLAD1interactor31.0000MoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain
PAPS_reduct (PF01507, IPR002500): Phosphoadenosine phosphosulfate reductase family
35 FN1oncoprotein260.271117.551fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
36 FUNDC2interactor200FUN14 (PF04930, IPR007014): FUN14 family
37 FUSsuppressor260.39477.783Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
38 FXR2interactor100.5837.234Agenet (PF05641, IPR008395, SM00743): Agenet domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
39 GOLGA2interactor60.8000.461ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
40 HDAC1suppressor160.30548.399FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
41 HDAC10interactor40.6670.733Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
42 HDAC2suppressor160.39032.097Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
43 HDAC3suppressor80.4767.067Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
44 HNRNPA1interactor290.38185.630RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
45 HSF4interactor100Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
46 HUWE1oncoprotein160.35236.860BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
47 IKZF1suppressor50.6670.800Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
48 ITCHinteractor70.7331.200C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
49 ITGA4interactor190.41234.796FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
50 JMJD1Cinteractor21.0000ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
RbpA (PF13397, IPR025182): RNA polymerase-binding protein
51 KIF21Binteractor21.0000CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
Thioredoxin_4 (PF13462, IPR012336): Thioredoxin
BORG_CEP (PF14957, IPR029273): Cdc42 effector
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
52 KIFAP3interactor21.0000KAP (PF05804): Kinesin-associated protein (KAP)
53 LMAN1interactor21.0000Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
54 LRRC47interactor30.6670.286B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
55 MAPK3oncoprotein31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
56 MASP1interactor21.0000CUB (PF00431, IPR000859, SM00042): CUB domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Trypsin (PF00089, IPR001254, SM00020): Trypsin
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
57 MKNK2interactor100ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component
Pkinase (PF00069, IPR000719): Protein kinase domain
58 MYL6interactor50.6000.845EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
59 NEDD4suppressor50.6671.000Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
60 NGEFinteractor100PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
61 NIF3L1interactor60.4003.467NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3)
62 NPM1suppressor300.369107.956Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
63 NTRK1oncoprotein440.192457.196I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
64 NUP98suppressor70.5244.621Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase
Nup96 (PF12110, IPR021967): Nuclear protein 96
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
65 OBSL1interactor230.29465.729BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
66 P3H1interactor70.4298.548TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
YfiO (PF13525): Outer membrane lipoprotein
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
MCM_N (PF14551, IPR027925): MCM N-terminal domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
67 P3H2interactor21.0000TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
YfiO (PF13525): Outer membrane lipoprotein
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
68 PAPOLAinteractor100.33319.086PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
69 PCF11interactor110.34526.169CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
zf-DBF (PF07535, IPR006572, SM00586): DBF zinc finger
CFIA_Pcf11 (PF11526, IPR021605): Subunit of cleavage factor IA Pcf11
70 POLR2Cinteractor80.4295.760RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
71 PRPF4Boncoprotein80.4645.797Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
Ureide_permease (PF07168, IPR009834): Ureide permease
Pkinase (PF00069, IPR000719): Protein kinase domain
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
72 PSMF1interactor40.6671.000PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
73 PTNoncoprotein50.5003.000PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
74 PYCR1interactor60.6001.321ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA
F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent
P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation
75 RBM48interactor30.6670.333DUF2284 (PF10050, IPR019271): Predicted metal-binding protein (DUF2284)
76 RCC1interactor120.25833.490RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
77 RIF1interactor50.8000.287Rif1_N (PF12231, IPR022031): Rap1-interacting factor 1 N terminal
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
78 RNF19Ainteractor21.0000IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
79 RNF2interactor190.27554.258zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
80 RNPS1interactor170.37548.024RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
Macoilin (PF09726, IPR019130): Transmembrane protein
81 RPA1suppressor220.41959.688Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
82 RPA2oncoprotein200.40065.013RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
83 RPA3interactor160.52419.910Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
84 RPL18interactor200.47423.652Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
85 RPLP1interactor120.56413.194Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
86 RPS3interactor220.42457.603KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
87 S100A13oncoprotein200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
88 SEMA5Boncoprotein100PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
89 SF3B1oncoprotein210.34349.204Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
90 SHC1oncoprotein50.6670.318PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
91 SHFM1interactor70.2868.702CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
92 SIPA1L1interactor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164)
IQCJ-SCHIP1 (PF15157, IPR029362): Fusion protein IQCJ-SCHIP1 with IQ-like motif
93 SIRT1suppressor110.44414.601DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
94 SIRT2suppressor31.0000SIR2 (PF02146, IPR003000): Sir2 family
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
95 SKIV2L2interactor120.50010.856DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
96 SLC44A1interactor100Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
Choline_transpo (PF04515, IPR007603): Plasma-membrane choline transporter
Halogen_Hydrol (PF10112, IPR018770): 5-bromo-4-chloroindolyl phosphate hydrolysis protein
TMEM154 (PF15102, IPR028064): TMEM154 protein family
97 SMURF1interactor100.4174.719C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
98 SNCAIPprotein found in more fusions40.6671.000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SNCAIP_SNCA_bd (PF16700, IPR032027): Synphilin-1 alpha-Synuclein-binding domain
99 SNRNP70interactor170.39723.310RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
100 SRPK1interactor120.6526.254FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
101 SRPK2oncoprotein190.43141.851DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
102 STAU1protein found in more fusions200.49130.485dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
103 TCERG1interactor130.5138.835FF (PF01846, IPR002713, SM00441): FF domain
WW (PF00397, IPR001202, SM00456): WW domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
FAM150 (PF15129, IPR029364): FAM150 family
104 TLE1interactor70.4674.750TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
105 TOP3Binteractor21.0000Topoisom_bac (PF01131, IPR013497): DNA topoisomerase
Toprim (PF01751, IPR006171, SM00493): Toprim domain
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
106 TRA2Ainteractor90.5283.407DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
107 TRIM27oncoprotein60.5004.167IncA (PF04156, IPR007285): IncA protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
108 TXNDC9interactor70.33312.083Thioredoxin (PF00085, IPR013766): Thioredoxin
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
109 VCAM1interactor140.40714.804C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
110 VIMsuppressor160.27644.260Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
111 WDR76interactor30.6670.222WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SPATIAL (PF15256): SPATIAL
112 WWOXsuppressor130.30822.094adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
113 XRCC4interactor31.0000XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
114 ZBTB48suppressor200BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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