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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins NTRK1, TFG (from a repository: Fri May 5 17:33:07 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)360
The number (and %) of the onco-proteins289 (80.28 %)
The number (and %) of the tumor suppressors69 (19.17 %)
Total number of binary PPIs (saturation %)2881 (4.46 %)
The number (and %) of affected PPIs372 (12.91 %)
The number of possible different fusions84
PPI diameter3
PPI radius2
The average degree of PPI15.294
Assortativity coefficient-0.2281
The network average Clustering coefficient0.418
The number (and %) of a zero Clustering coefficients19 (5.28 %)
The number (and %) of a zero Betweenness Centrality33 (9.17 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: TFG,NTRK1 All fusions
: X85960;
Proteins found in more fusions ABL2 (see 2 fusions); NTRK1/TFG (see 1 fusions); TCF12 (see 2 fusions); CUL1 (see 3 fusions); WDR77 (see 1 fusions); HOOK3 (see 4 fusions); GRB2 (see 1 fusions); SLC9A3R1 (see 2 fusions); LGALS3BP (see 2 fusions); MAP3K1 (see 1 fusions); HNRNPA3/NONO (see 1 fusions); VAC14 (see 1 fusions); EWSR1 (see 2 fusions); EIF2AK2 (see 1 fusions); PRDX1 (see 1 fusions); TFRC (see 1 fusions); CTTN (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); MSH2 (see 1 fusions); PTBP1 (see 1 fusions); SRSF2 (see 1 fusions); HSP90AA1 (see 2 fusions); SFPQ (see 6 fusions); GNAS (see 5 fusions); APEH (see 1 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); GSE1 (see 1 fusions); SRPK2 (see 1 fusions); DDX5/PIK3CA (see 1 fusions); CALR (see 6 fusions); NTRK1/TPM3 (see 3 fusions); STAT3 (see 2 fusions); HNRNPD (see 1 fusions); EML4 (see 3 fusions); NEDD4L (see 3 fusions); MAD1L1 (see 3 fusions); PRPF8 (see 3 fusions); ARHGEF12 (see 2 fusions); RRM1 (see 1 fusions); HSPB1 (see 4 fusions); DKC1 (see 2 fusions); CSNK2A1 (see 1 fusions); SHC1 (see 1 fusions); PML (see 4 fusions); CBLB (see 4 fusions); CHD4 (see 6 fusions); GAPDH (see 2 fusions); HSPA8/HSPD1 (see 1 fusions); RBMX (see 3 fusions); PPFIBP1 (see 1 fusions); GAB2 (see 3 fusions); EPS15 (see 1 fusions); MAPK1 (see 1 fusions); EEF1A1 (see 1 fusions); CBL (see 1 fusions); NUP214 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); CTNNA1 (see 3 fusions); CDK6 (see 1 fusions); MYC (see 1 fusions); MAPRE1 (see 1 fusions); PIK3R1 (see 1 fusions); VCL (see 2 fusions); RTN4 (see 11 fusions); PTPN11 (see 1 fusions); BCR/ABL1 (see 183 fusions); FUS/PKM (see 1 fusions); ABCC1 (see 1 fusions); LYN (see 2 fusions); TRIM33 (see 1 fusions); TPM3 (see 2 fusions); PABPC1 (see 2 fusions); SQSTM1 (see 5 fusions); RABEP1 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); BOP1 (see 1 fusions); JAK1 (see 1 fusions); NTRK1/TPR (see 1 fusions); SYNE1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TFGparental protein240.1421602.437ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
2 NTRK1parental protein3490.03987824.398I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
3 AARS2oncoprotein100tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
4 ABCB1oncoprotein30.6670.333ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
5 ABCC1oncoprotein80.28656.156ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class
DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
6 ABL1oncoprotein390.257262.965Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
7 ABL2oncoprotein80.7143.285Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NHS (PF15273, IPR024845): NHS-like
8 ACADMoncoprotein50.9000.250Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
9 ACSL3oncoprotein30.6670.200AMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
10 ACVR1Boncoprotein40.6670.605Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
11 ADGRL2oncoprotein1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
Gal_Lectin (PF02140, IPR000922): Galactose binding lectin domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
Latrophilin (PF02354, IPR003334): Latrophilin Cytoplasmic C-terminal region
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
zf-C2HCIx2C (PF10782, IPR019718): Zinc-finger
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain
12 AFDNoncoprotein70.3818.878DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FHA (PF00498, IPR000253, SM00240): FHA domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Pap_E4 (PF02711, IPR003861): E4 protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
ARGLU (PF15346): Arginine and glutamate-rich 1
13 AIFM1oncoprotein70.3337.977Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence
14 ALDH2oncoprotein40.33327.508Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
DUF1235 (PF06822, IPR009641): Protein of unknown function (DUF1235)
15 AMFRoncoprotein130.27321.127CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
16 ANAPC1suppressor40.6671.167PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
17 ANKRD44oncoprotein30.6670.667Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
18 ANP32Asuppressor70.4764.908SDA1 (PF05285, IPR007949): SDA1
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_9 (PF14580): Leucine-rich repeat
19 ANP32Boncoprotein80.5007.197FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
SDA1 (PF05285, IPR007949): SDA1
LRR_9 (PF14580): Leucine-rich repeat
20 ANXA1suppressor140.24433.220Annexin (PF00191, IPR018502, SM00335): Annexin
21 ANXA5oncoprotein50.50014.112Annexin (PF00191, IPR018502, SM00335): Annexin
22 APEHoncoprotein60.4005.667Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
23 ARHGAP32oncoprotein110.7454.799PX (PF00787, IPR001683, SM00312): PX domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
24 ARHGAP35oncoprotein31.0000FF (PF01846, IPR002713, SM00441): FF domain
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
25 ARHGEF12suppressor40.6670.800PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS-like (PF09128, IPR015212): Regulator of G protein signalling-like domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
26 ARHGEF2oncoprotein80.5364.476IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
27 ASNSoncoprotein80.5364.984Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
28 ASPSCR1oncoprotein30.6671.111DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
29 ATIConcoprotein90.38914.935AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
30 BCLAF1oncoprotein70.4764.762API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
31 BCRsuppressor160.48328.577Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
32 BOP1oncoprotein40.6670.500BOP1NT (PF08145, IPR012953, SM01035): BOP1NT (NUC169) domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3038 (PF11237, IPR021399): Protein of unknown function (DUF3038)
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
33 BRAT1oncoprotein100HEAT (PF02985, IPR000357): HEAT repeat
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
34 BRD3oncoprotein50.6001.393DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
IncA (PF04156, IPR007285): IncA protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
35 BREoncoprotein50.2005.167BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
36 C2CD5oncoprotein60.4674.513C2 (PF00168, IPR000008, SM00239): C2 domain
YbjQ_1 (PF01906, IPR002765): Putative heavy-metal-binding
37 CADoncoprotein180.40532.811Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
38 CALRoncoprotein170.44229.113Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
39 CARM1oncoprotein90.5835.330K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
40 CARSoncoprotein40.5002.286tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain
41 CAV1suppressor220.251108.702Caveolin (PF01146, IPR001612): Caveolin
42 CBLsuppressor380.306200.189Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
43 CBLBoncoprotein150.61578.088Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
44 CCAR1suppressor30.6670.167Cucumo_2B (PF03263, IPR004946): Cucumovirus protein 2B
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
IncA (PF04156, IPR007285): IncA protein
Presenilin (PF01080, IPR001108): Presenilin
SAP (PF02037, IPR003034, SM00513): SAP domain
FimP (PF09766, IPR019163): Fms-interacting protein
DBC1 (PF14443, IPR025954, SM01122): DBC1
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
S1-like (PF14444, IPR025223): S1-like
DUF4481 (PF14800, IPR028054): Domain of unknown function (DUF4481)
FAM176 (PF14851): FAM176 family
45 CCDC6oncoprotein90.4449.804CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
46 CCNT1oncoprotein70.5334.984Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
MDFI (PF15316, IPR026134): MyoD family inhibitor
47 CDC27oncoprotein90.32113.385TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
48 CDK1oncoprotein240.253126.841Pkinase (PF00069, IPR000719): Protein kinase domain
49 CDK11Boncoprotein70.4673.803DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
50 CDK2suppressor940.1192543.367Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
51 CDK4oncoprotein230.261172.077Pkinase (PF00069, IPR000719): Protein kinase domain
52 CDK5oncoprotein120.27326.675Pkinase (PF00069, IPR000719): Protein kinase domain
53 CDK6suppressor170.333128.329Pkinase (PF00069, IPR000719): Protein kinase domain
54 CHD4oncoprotein140.43626.682CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
55 CHGAoncoprotein100Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding
56 CICsuppressor30.6670.633HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
MRI (PF15325, IPR028278): Modulator of retrovirus infection
DUF4819 (PF16090, IPR032147): Domain of unknown function (DUF4819)
57 CLIC4oncoprotein80.4298.105GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
58 CLTConcoprotein310.224225.056Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
59 CRKLoncoprotein260.357121.432SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
60 CSDE1oncoprotein50.5000.981CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
SUZ-C (PF12901, IPR024642): SUZ-C motif
S1-like (PF14444, IPR025223): S1-like
61 CSE1Loncoprotein120.43917.327CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus
Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
62 CSNK1A1suppressor90.30610.416Pkinase (PF00069, IPR000719): Protein kinase domain
63 CSNK2A1oncoprotein440.141571.745Pkinase (PF00069, IPR000719): Protein kinase domain
64 CTNNA1oncoprotein140.35929.280Vinculin (PF01044, IPR006077): Vinculin family
65 CTNNB1oncoprotein430.192488.062Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
66 CTNND1suppressor90.4726.394Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
67 CTTNoncoprotein160.28647.514FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
68 CUL1suppressor650.1831064.915Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
69 CUL4Boncoprotein380.304354.446Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
70 CUX1suppressor50.5004.887Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein
CUT (PF02376, IPR003350, SM01109): CUT domain
DegS (PF05384, IPR008595): Sensor protein DegS
DivIC (PF04977, IPR007060): Septum formation initiator
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Swi5 (PF07061, IPR010760): Swi5
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
ApoO (PF09769, IPR019166): Apolipoprotein O
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
71 DAB2IPsuppressor30.6670.600C2 (PF00168, IPR000008, SM00239): C2 domain
PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
72 DBN1oncoprotein230.289110.000Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
73 DDX1oncoprotein260.354111.692DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
74 DDX10oncoprotein100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF2390 (PF09523, IPR012659): Protein of unknown function (DUF2390)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217)
PAS_11 (PF14598): PAS domain
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
75 DDX5oncoprotein240.31298.319DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
76 DDX6oncoprotein70.3816.149DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
77 DHX9oncoprotein370.230359.677DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
78 DICER1suppressor60.6002.008DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
79 DKC1oncoprotein80.3815.434DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain
PUA (PF01472, IPR002478, SM00359): PUA domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
80 DLG1suppressor40.5001.418L27_1 (PF09058, IPR015143): L27_1
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037)
MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK
PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
81 DNAJC9oncoprotein70.5243.811DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
82 DNMT1suppressor110.42214.761BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
83 DYRK1Aoncoprotein80.23861.526DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM199X (PF15814, IPR029672): Protein family FAM199X
84 EEF1A1suppressor410.241320.091GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
85 EGFRoncoprotein980.1063295.258Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
86 EIF1AXoncoprotein6012.144eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1
87 EIF2AK2oncoprotein170.32551.590dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Pkinase (PF00069, IPR000719): Protein kinase domain
88 EIF3Aoncoprotein110.6009.891DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
89 EIF3Concoprotein130.51322.143eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399, IPR000717, SM00088): PCI domain
90 EIF3Eoncoprotein120.50019.563eIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
91 EIF3Fsuppressor170.37553.641JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
92 EIF3Ioncoprotein160.39241.791ISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
93 EIF4Eoncoprotein70.4295.175IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
94 EIF4G1oncoprotein150.36243.501DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
95 ELAC2oncoprotein70.4299.500Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit
Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
Lactamase_B_4 (PF13691, IPR027794): tRNase Z endonuclease
96 ELAVL1oncoprotein850.0662960.820RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
97 ELMO1oncoprotein21.0000ELMO_CED12 (PF04727, IPR006816): ELMO/CED-12 family
FERM_N (PF09379, IPR018979): FERM N-terminal domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
Imm42 (PF15593, IPR028958): Immunity protein 42
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
98 EML4oncoprotein40.6671.583HELP (PF03451, IPR005108): HELP motif
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
SlyX (PF04102, IPR007236): SlyX
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
99 ENAHoncoprotein60.4007.087MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
100 ENO1oncoprotein200.41167.943Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
101 EPHA2suppressor140.48722.398fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
102 EPS15oncoprotein210.31673.349Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
103 EPS15L1oncoprotein30.6670.667CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
104 ERCC2oncoprotein100DEAD_2 (PF06733, IPR010614): DEAD_2
HBB (PF06777, IPR010643): Helical and beta-bridge domain
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C_2 (PF13307, IPR006555): Helicase C-terminal domain
TIR_2 (PF13676, IPR000157): TIR domain
SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
105 ERCC4oncoprotein40.5002.167ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
LUC7 (PF03194, IPR004882): LUC7 N_terminus
T2SSM_b (PF10741, IPR007690): Type II secretion system (T2SS), protein M subtype b
HHH_5 (PF14520): Helix-hairpin-helix domain
106 EWSR1oncoprotein480.167858.140RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
107 EXOC4oncoprotein40.5001.612DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain
Vps51 (PF08700): Vps51/Vps67
108 FABP3suppressor21.0000Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
109 FANCD2oncoprotein80.5715.865FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
110 FBXO11oncoprotein40.5001.776TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
111 FEN1oncoprotein130.33355.6165_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
112 FIP1L1oncoprotein60.4005.856Fip1 (PF05182, IPR007854): Fip1 motif
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
Auts2 (PF15336): Autism susceptibility gene 2 protein
113 FLIIoncoprotein110.47374.329Gelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
114 FMNL3oncoprotein100Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
STAS_2 (PF13466, IPR002645): STAS domain
115 FSCN1oncoprotein110.36424.975Fascin (PF06268, IPR022768): Fascin domain
116 FUBP1oncoprotein90.6116.577DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
117 FUSsuppressor500.245445.298Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
118 GAB1oncoprotein100.8671.128PH (PF00169, IPR001849, SM00233): PH domain
119 GAB2oncoprotein170.48323.422PH (PF00169, IPR001849, SM00233): PH domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
120 GAKoncoprotein90.44412.908DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
121 GAPDHoncoprotein360.343217.755Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
122 GGHoncoprotein31.0000Peptidase_C26 (PF07722, IPR011697): Peptidase C26
123 GMPSoncoprotein50.6001.358GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
GMP_synt_C (PF00958, IPR001674): GMP synthase C terminal domain
NAD_synthase (PF02540, IPR022310): NAD synthase
124 GNASoncoprotein100.30615.863G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
125 GOT2oncoprotein51.0000Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
126 GPHNoncoprotein40.6670.667MoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain
MoeA_C (PF03454, IPR005111): MoeA C-terminal region (domain IV)
MoeA_N (PF03453, IPR005110): MoeA N-terminal region (domain I and II)
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
127 GRB2oncoprotein680.1741402.136SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
128 GRNoncoprotein70.4298.850Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
129 GSE1oncoprotein60.4001.584CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DUF3736 (PF12540, IPR022207): Protein of unknown function (DUF3736)
AAA_11 (PF13086): AAA domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
130 GSPT1oncoprotein80.3937.856GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
131 HDAC6oncoprotein300.268238.272Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
132 HDLBPoncoprotein80.3218.634BMC (PF00936, IPR000249, SM00877): BMC domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
KH_5 (PF13184, IPR025249): NusA-like KH domain
SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
133 HIP1oncoprotein60.6002.119ANTH (PF07651, IPR011417): ANTH domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
134 HIST1H1Boncoprotein60.4673.809Pneumo_att_G (PF05539, IPR008781): Pneumovirinae attachment membrane glycoprotein G
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
135 HIST1H1Concoprotein140.28643.525Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
136 HLA-Aoncoprotein60.6003.500DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
137 HLTFsuppressor80.4294.933HIRAN (PF08797, IPR014905, SM00910): HIRAN domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
138 HMGB1oncoprotein130.28226.429HMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
139 HNRNPA2B1oncoprotein300.326248.072RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
140 HNRNPA3oncoprotein230.44749.013IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
141 HNRNPDoncoprotein380.290258.025CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
142 HNRNPH1oncoprotein210.44349.146RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
143 HNRNPKoncoprotein420.268298.353ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
144 HOOK3oncoprotein31.0000HOOK (PF05622, IPR008636): HOOK protein
145 HSP90AA1oncoprotein660.1781041.334HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
146 HSP90AB1oncoprotein460.278318.454HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
147 HSP90B1suppressor230.31682.313CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
148 HSPA5oncoprotein590.204765.234HSP70 (PF00012, IPR013126): Hsp70 protein
149 HSPA8oncoprotein490.263438.374HSP70 (PF00012, IPR013126): Hsp70 protein
150 HSPA9oncoprotein280.38492.139HSP70 (PF00012, IPR013126): Hsp70 protein
151 HSPB1oncoprotein350.226394.160HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
152 HSPD1suppressor230.37990.729Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
153 HSPH1oncoprotein160.34245.626HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
154 HUWE1oncoprotein660.1491442.421BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
155 IDH1suppressor50.7002.272Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
156 IDH2oncoprotein40.6671.455Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
157 IGF1Roncoprotein150.41929.203fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
158 IGHG1oncoprotein80.14319.265C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
159 ILF3oncoprotein280.310131.994dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
160 INPPL1oncoprotein160.55820.711Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
161 INTS6suppressor21.0000VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus
DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
162 IRF2BP2oncoprotein30.6670.400zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Bd3614_N (PF14442, IPR025854): Bd3614-like deaminase N-terminal
163 IRS2oncoprotein120.45515.162CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
164 JAK1oncoprotein180.40436.985FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
165 KIAA1524oncoprotein40.6670.394Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ParcG (PF10274, IPR019399): Parkin co-regulated protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
166 KIF14oncoprotein30.6670.554FHA (PF00498, IPR000253, SM00240): FHA domain
LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
SdrG_C_C (PF10425, IPR011266): C-terminus of bacterial fibrinogen-binding adhesin
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Gluconate_2-dh3 (PF13618, IPR027056): Gluconate 2-dehydrogenase subunit 3
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
167 KTN1oncoprotein21.0000ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
168 L1CAMoncoprotein100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
Bravo_FIGEY (PF13882, IPR026966): Bravo-like intracellular region
Ig_3 (PF13927): Immunoglobulin domain
169 LGALS3BPoncoprotein160.57120.370BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
170 LRRFIP1oncoprotein60.8001.238CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3
LRRFIP (PF09738, IPR019139): LRRFIP family
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
Coilin_N (PF15862, IPR031722): Coilin N-terminus
171 LYNoncoprotein190.30154.781Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
172 MAD1L1suppressor80.33310.000MAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
173 MAP2oncoprotein100.30615.166MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
RII_binding_1 (PF10522, IPR018459): RII binding domain
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
174 MAP3K1oncoprotein100.33320.862zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
175 MAP4oncoprotein50.5002.036SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
176 MAPK1oncoprotein230.186147.157Pkinase (PF00069, IPR000719): Protein kinase domain
177 MAPK7oncoprotein110.4676.680Pkinase (PF00069, IPR000719): Protein kinase domain
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
178 MAPRE1oncoprotein180.28760.791CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
179 MARCKSL1oncoprotein50.6001.507MARCKS (PF02063, IPR002101): MARCKS family
180 MARSoncoprotein90.5007.955Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
181 MATKoncoprotein50.6001.222Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
182 MCM2oncoprotein930.1472364.299AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
183 MCM5oncoprotein330.239221.296MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
184 MED12oncoprotein30.6671.000Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
185 MED17oncoprotein30.6671.000Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
186 METAP2oncoprotein40.5001.567Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
187 MGEA5oncoprotein50.7000.959NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase
188 MLH1suppressor200.22691.719DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
189 MRE11Aoncoprotein190.30783.734APG6 (PF04111, IPR007243): Autophagy protein Apg6
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
190 MSH2suppressor230.264122.121MutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
AAA_27 (PF13514): AAA domain
191 MSH3oncoprotein60.9330.125MutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
192 MSH6oncoprotein150.43828.777MutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
PWWP (PF00855, IPR000313, SM00293): PWWP domain
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
193 MSI2oncoprotein40.5001.338NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
194 MTA1oncoprotein90.44419.023BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
195 MYBBP1Asuppressor110.38217.793DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
196 MYConcoprotein720.1121659.909HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
197 MYH9suppressor360.224294.698IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
198 NAA10oncoprotein40.5003.521Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
199 NACAoncoprotein110.41814.282NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
200 NCAPD2oncoprotein60.4006.130Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
HEAT (PF02985, IPR000357): HEAT repeat
LrgA (PF03788, IPR005538): LrgA family
Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
201 NCOA4suppressor200.732ARA70 (PF12489, IPR022174): Nuclear coactivator
202 NEDD4Lsuppressor80.3819.727WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
203 NELFCDoncoprotein40.6672.111TH1 (PF04858, IPR006942): TH1 protein
204 NGFRsuppressor70.33350.810LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
205 NIPBLoncoprotein70.33312.706DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Zip (PF02535, IPR003689): ZIP Zinc transporter
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion
Nipped-B_C (PF12830, IPR024986): Sister chromatid cohesion C-terminus
HEAT_2 (PF13646): HEAT repeats
DNA_repr_REX1B (PF14966): DNA repair REX1-B
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
T3SS_basalb_I (PF17001, IPR012670): Type III secretion basal body protein I, YscI, HrpB, PscI
206 NMT1oncoprotein110.45514.860NMT (PF01233, IPR022676): Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
NMT_C (PF02799, IPR022677): Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
207 NONOoncoprotein240.237126.290GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PAS_7 (PF12860): PAS fold
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
208 NOTCH3suppressor50.5003.600Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
209 NRCAMsuppressor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain
Bravo_FIGEY (PF13882, IPR026966): Bravo-like intracellular region
Ig_3 (PF13927): Immunoglobulin domain
SIT (PF15330): SHP2-interacting transmembrane adaptor protein, SIT
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
210 NTRK3suppressor50.6001.164I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
211 NUMA1oncoprotein110.40015.187Colicin (PF01024, IPR000293): Colicin pore forming domain
Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
212 NUP133oncoprotein60.5332.757Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal
213 NUP214oncoprotein31.0000dCache_2 (PF08269, IPR004010, SM01049): Cache domain
HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1
NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159
214 NUP93oncoprotein50.5001.755Nic96 (PF04097, IPR007231): Nup93/Nic96
215 PABPC1oncoprotein240.32095.367RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
216 PAF1oncoprotein50.4002.935Paf1 (PF03985, IPR007133): Paf1
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
217 PCBP1oncoprotein280.299143.541Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
218 PCM1oncoprotein90.33317.533FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
AAA_23 (PF13476): AAA domain
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
219 PCNAoncoprotein390.201369.650PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
220 PDCD4suppressor70.4297.156Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
MA3 (PF02847, IPR003891, SM00544): MA3 domain
221 PDGFRAoncoprotein130.57613.772Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
LAT (PF15234, IPR008359): Linker for activation of T-cells
222 PDGFRBoncoprotein200.43348.596I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
Ig_3 (PF13927): Immunoglobulin domain
TonB_N (PF16031): TonB N-terminal region
223 PDS5Bsuppressor60.8001.175AT_hook (PF02178, IPR017956, SM00384): AT hook motif
HEAT (PF02985, IPR000357): HEAT repeat
Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
DUF3665 (PF12427, IPR024614): Branched-chain amino acid aminotransferase
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
224 PFN1suppressor100.37822.255Profilin (PF00235, IPR005455, SM00392): Profilin
225 PHBsuppressor180.288194.275Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
226 PHF20oncoprotein100GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776)
227 PHF6suppressor90.33314.997zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
228 PICALMoncoprotein170.36044.957ANTH (PF07651, IPR011417): ANTH domain
229 PIK3CAoncoprotein90.5286.728PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321)
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
230 PIK3CBoncoprotein80.7502.294PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
RWD (PF05773, IPR006575, SM00591): RWD domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
Tom37_C (PF11801, IPR019564): Tom37 C-terminal domain
DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381)
231 PIK3R1oncoprotein300.362130.356RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
232 PIK3R2oncoprotein220.46349.307RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
233 PKMoncoprotein290.340116.037PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
234 PLCG1oncoprotein250.320103.433C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
235 PLK1suppressor170.199100.754Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
236 PMLsuppressor320.204245.005zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
237 PMS1oncoprotein110.35616.212DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
238 PPFIBP1oncoprotein50.6671.083DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
XkdW (PF09636, IPR019094): XkdW protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837)
239 PPM1Eoncoprotein100PP2C (PF00481, IPR001932): Protein phosphatase 2C
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
240 PPP1CAsuppressor260.274125.707Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
241 PPP2R1Aoncoprotein300.191244.892TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
242 PRDX1oncoprotein220.31059.955AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
243 PRPF4Boncoprotein60.6672.452Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
Ureide_permease (PF07168, IPR009834): Ureide permease
Pkinase (PF00069, IPR000719): Protein kinase domain
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
244 PRPF8oncoprotein210.29577.931PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
245 PRPS1oncoprotein40.6671.340Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
246 PSMA5oncoprotein150.30548.729Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
247 PSMD2oncoprotein140.36334.804PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
248 PTBP1oncoprotein220.47136.890RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
249 PTK7oncoprotein100Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
250 PTPN11suppressor230.42062.984SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
251 RAB11Aoncoprotein90.4177.460Ras (PF00071, IPR001806, SM00173): Ras family
252 RAB5Concoprotein130.26934.041Ras (PF00071, IPR001806, SM00173): Ras family
253 RABEP1oncoprotein50.5002.436Fib_succ_major (PF09603, IPR011871): Fibrobacter succinogenes major domain (Fib_succ_major)
Rab5-bind (PF09311, IPR015390): Rabaptin-like protein
Rabaptin (PF03528, IPR018514): Rabaptin
254 RABL6oncoprotein21.0000eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Ras (PF00071, IPR001806, SM00173): Ras family
255 RACK1suppressor240.289101.836WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
256 RAD21oncoprotein400.163569.827Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
257 RAD23Bsuppressor120.30330.151K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
258 RALAoncoprotein90.33313.152ArgK (PF03308, IPR005129): ArgK protein
Ras (PF00071, IPR001806, SM00173): Ras family
ThiF (PF00899, IPR000594): ThiF family
259 RANoncoprotein130.25633.455Ras (PF00071, IPR001806, SM00173): Ras family
260 RANBP3oncoprotein60.6002.912Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
261 RAP1Asuppressor110.23630.755Ras (PF00071, IPR001806, SM00173): Ras family
262 RAP1GDS1oncoprotein100.5788.993Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
263 RASA1oncoprotein110.54513.997C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
264 RB1suppressor260.206198.801RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
265 RBBP4oncoprotein140.33036.022eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
266 RBL1suppressor110.36420.541RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
267 RBM15oncoprotein50.6001.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SPOC (PF07744, IPR012921): SPOC domain
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
268 RBM39oncoprotein140.27537.634RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
269 RBMXsuppressor150.49513.870RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
270 RCC2oncoprotein50.6001.145RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
271 RECQLoncoprotein31.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Lipoprotein_3 (PF00938, IPR001595): Lipoprotein
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
272 RELAoncoprotein180.26564.233DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
273 REToncoprotein130.56112.893Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
274 RGS19oncoprotein100RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
275 RNGTToncoprotein21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
mRNA_cap_C (PF03919, IPR013846): mRNA capping enzyme, C-terminal domain
mRNA_cap_enzyme (PF01331, IPR001339): mRNA capping enzyme, catalytic domain
276 ROR2suppressor31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Kringle (PF00051, IPR000001): Kringle domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Fz (PF01392, IPR020067, SM00063): Fz domain
TMEM154 (PF15102, IPR028064): TMEM154 protein family
277 RPL10suppressor270.211356.866Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
278 RPL5suppressor220.34375.202Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
279 RPN1oncoprotein150.37128.372Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
280 RPS6KA1oncoprotein80.35711.095Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
281 RRM1oncoprotein40.6670.754ATP-cone (PF03477, IPR005144): ATP cone domain
Ribonuc_red_lgC (PF02867, IPR000788): Ribonucleotide reductase, barrel domain
Ribonuc_red_lgN (PF00317, IPR013509): Ribonucleotide reductase, all-alpha domain
282 RTN4suppressor80.38112.150CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Reticulon (PF02453, IPR003388): Reticulon
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
283 RUVBL1oncoprotein250.261112.635TIP49 (PF06068, IPR010339): TIP49 C-terminus
284 RUVBL2oncoprotein210.31666.881TIP49 (PF06068, IPR010339): TIP49 C-terminus
285 S100A7oncoprotein50.3003.494S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
286 S100A9oncoprotein180.28755.128S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
287 SBNO1oncoprotein30.6670.667Helicase_C_4 (PF13871, IPR026937): C-terminal domain on Strawberry notch homologue
AAA_34 (PF13872): P-loop containing NTP hydrolase pore-1
288 SCYL1suppressor21.0000HEAT (PF02985, IPR000357): HEAT repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
289 SEL1Loncoprotein60.6671.599fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
290 SEPT2oncoprotein110.27320.882FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
291 SEPT9oncoprotein70.4765.606Septin (PF00735, IPR000038): Septin
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
292 SEToncoprotein140.41023.786NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
293 SF3B1oncoprotein190.36354.974Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
294 SFPQoncoprotein320.241200.017GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
295 SH2B2oncoprotein70.8670.487PH (PF00169, IPR001849, SM00233): PH domain
Phe_ZIP (PF08916, IPR015012): Phenylalanine zipper
SH2 (PF00017, IPR000980, SM00252): SH2 domain
296 SHC1oncoprotein500.203653.135PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
297 SIN3Aoncoprotein180.24874.326Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
298 SLC16A1oncoprotein100MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
299 SLC9A3R1suppressor70.4004.141EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
300 SMARCA4suppressor230.202130.720DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
301 SMC1Aoncoprotein150.34192.174SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
302 SMC3oncoprotein160.308116.486SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
303 SOS1oncoprotein130.65415.031Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
304 SPTAN1oncoprotein230.296111.401EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
305 SQSTM1oncoprotein230.242105.020PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
306 SRConcoprotein270.283221.161Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
307 SRPK2oncoprotein360.109397.371DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
308 SRSF2oncoprotein150.30837.486RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
309 SRSF6oncoprotein90.4179.010RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Tox-HNH-EHHH (PF15657, IPR028048): HNH/Endo VII superfamily nuclease toxins
310 ST13suppressor100.44411.527Hox9_act (PF04617, IPR006711): Hox9 activation region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
311 STAG2oncoprotein70.7622.233AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
STAG (PF08514, IPR013721): STAG domain
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
312 STAT3suppressor280.262154.910SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
313 STAT5Boncoprotein80.6198.225SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
314 STOML2oncoprotein90.4728.280Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
Band_7_C (PF16200, IPR032435): C-terminal region of band_7
315 STRNoncoprotein50.5001.390CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
316 SYNE1oncoprotein31.0000Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
POX (PF07526, IPR006563, SM00574): Associated with HOX
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
THOC7 (PF05615, IPR008501): Tho complex subunit 7
TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
KASH (PF10541, IPR012315): Nuclear envelope localisation domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416)
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
317 SYNPO2suppressor40.5001.166Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
318 TACC3oncoprotein60.3339.333TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
319 TBL1XR1oncoprotein40.8330.400LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
320 TCF12oncoprotein50.8330.667HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
321 TFRConcoprotein70.6673.228PA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
DUF3855 (PF12967, IPR024482): Domain of Unknown Function with PDB structure (DUF3855)
322 THADAoncoprotein30.6670.293HEAT (PF02985, IPR000357): HEAT repeat
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
DUF2428 (PF10350, IPR019442): Putative death-receptor fusion protein (DUF2428)
323 THRAP3oncoprotein100.4009.608API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
324 TOM1oncoprotein40.5001.667GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
325 TOP1oncoprotein270.288151.999DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
326 TOP2Aoncoprotein120.19731.774DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Toprim (PF01751, IPR006171, SM00493): Toprim domain
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
327 TOP2Boncoprotein90.33328.713CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DASH_Spc19 (PF08287, IPR013251): Spc19
DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Toprim (PF01751, IPR006171, SM00493): Toprim domain
Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
328 TOP3Aoncoprotein21.0000A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
Topoisom_bac (PF01131, IPR013497): DNA topoisomerase
Toprim (PF01751, IPR006171, SM00493): Toprim domain
zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-GRF (PF06839, IPR010666): GRF zinc finger
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
329 TPM3oncoprotein180.35352.144Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
330 TPM4oncoprotein120.45514.085Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
331 TPRoncoprotein140.34138.256Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
XhlA (PF10779, IPR019715): Haemolysin XhlA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
332 TRAF3oncoprotein90.07131.548ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
Spc29 (PF17082, IPR031392): Spindle Pole Component 29
333 TRAP1oncoprotein140.26429.393HSP90 (PF00183, IPR001404): Hsp90 protein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
334 TRIM24suppressor70.3335.226PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
zf-MYND (PF01753, IPR002893): MYND finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
Imm68 (PF15583, IPR028276): Immunity protein 68
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
335 TRIM33oncoprotein110.33329.283PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
Spectrin (PF00435, IPR002017): Spectrin repeat
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
336 TRIOoncoprotein30.6670.500T3SS_needle_E (PF08988, IPR012671): Type III secretion system, cytoplasmic E component of needle
GRP (PF07172, IPR010800): Glycine rich protein family
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pap_E4 (PF02711, IPR003861): E4 protein
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
337 TSC2suppressor100.28923.416Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
Tuberin (PF03542, IPR018515): Tuberin
DUF3384 (PF11864, IPR024584): Domain of unknown function (DUF3384)
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
338 TSG101suppressor120.30932.149APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
339 TUBA1Aoncoprotein220.39056.650Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
340 TXNoncoprotein170.43430.019Thioredoxin (PF00085, IPR013766): Thioredoxin
341 U2AF1oncoprotein160.39229.198DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
342 UBE3Aoncoprotein180.24381.030HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
343 UCHL5oncoprotein230.186232.724Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
344 UQCRC2oncoprotein210.27194.259Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
345 USP15oncoprotein100.41718.018UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
346 USP39oncoprotein110.34522.536UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
347 USP4oncoprotein110.37819.227UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
348 USP7oncoprotein310.172438.518MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
349 VAC14oncoprotein40.6670.456TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
350 VAV2oncoprotein110.41816.815PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
CotJB (PF12652, IPR024207): CotJB protein
351 VCLoncoprotein150.38520.534Vinculin (PF01044, IPR006077): Vinculin family
352 VGFoncoprotein100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
353 WASF2oncoprotein100RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
WH2 (PF02205, IPR003124, SM00246): WH2 motif
WASH_WAHD (PF11945, IPR021854): WAHD domain of WASH complex
354 WDR11suppressor100PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PQQ_2 (PF13360, IPR002372): PQQ-like domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
355 WDR77oncoprotein70.5331.699LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
356 WDR82oncoprotein50.8000.432MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
357 WRNoncoprotein70.6001.988DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
HRDC (PF00570, IPR002121, SM00341): HRDC domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
HTH_40 (PF14493, IPR029491): Helix-turn-helix domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
358 XRCC6oncoprotein310.202235.547Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
359 YBX1oncoprotein260.286113.642CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
360 YWHAEoncoprotein430.164605.06014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AARS2oncoproteintRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
X85960
2 ABCC1oncoproteinABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class
DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
X85960
3 ACADMoncoproteinAcyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
X85960
4 ACSL3oncoproteinAMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
X85960
5 ADGRL2oncoprotein7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
Gal_Lectin (PF02140, IPR000922): Galactose binding lectin domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
Latrophilin (PF02354, IPR003334): Latrophilin Cytoplasmic C-terminal region
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
zf-C2HCIx2C (PF10782, IPR019718): Zinc-finger
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain
X85960
6 ALDH2oncoproteinAldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
DUF1235 (PF06822, IPR009641): Protein of unknown function (DUF1235)
X85960
7 AMFRoncoproteinCUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
X85960
8 ANAPC1suppressorPC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
X85960
9 ANXA1suppressorAnnexin (PF00191, IPR018502, SM00335): AnnexinX85960
10 ANXA5oncoproteinAnnexin (PF00191, IPR018502, SM00335): AnnexinX85960
11 APEHoncoproteinPeptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase familyX85960
12 ARHGAP35oncoproteinFF (PF01846, IPR002713, SM00441): FF domain
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
X85960
13 ASNSoncoproteinAsn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
X85960
14 ASPSCR1oncoproteinDUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
X85960
15 ATIConcoproteinAICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
X85960
16 BOP1oncoproteinBOP1NT (PF08145, IPR012953, SM01035): BOP1NT (NUC169) domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3038 (PF11237, IPR021399): Protein of unknown function (DUF3038)
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
X85960
17 BRD3oncoproteinDUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
IncA (PF04156, IPR007285): IncA protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
X85960
18 BREoncoproteinBRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)X85960
19 C2CD5oncoproteinC2 (PF00168, IPR000008, SM00239): C2 domain
YbjQ_1 (PF01906, IPR002765): Putative heavy-metal-binding
X85960
20 CALRoncoproteinCalreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
X85960
21 CARM1oncoproteinK_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
X85960
22 CARSoncoproteintRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domainX85960
23 CCDC6oncoproteinCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
X85960
24 CHGAoncoproteinGranin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding
X85960
25 CICsuppressorHMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
MRI (PF15325, IPR028278): Modulator of retrovirus infection
DUF4819 (PF16090, IPR032147): Domain of unknown function (DUF4819)
X85960
26 CLIC4oncoproteinGST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
X85960
27 CSDE1oncoproteinCSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
SUZ-C (PF12901, IPR024642): SUZ-C motif
S1-like (PF14444, IPR025223): S1-like
X85960
28 CTNNA1oncoproteinVinculin (PF01044, IPR006077): Vinculin familyX85960
29 DAB2IPsuppressorC2 (PF00168, IPR000008, SM00239): C2 domain
PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
X85960
30 DDX1oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
X85960
31 DDX5oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
X85960
32 DDX6oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
X85960
33 DICER1suppressorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
X85960
34 DKC1oncoproteinDKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain
PUA (PF01472, IPR002478, SM00359): PUA domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
X85960
35 DNAJC9oncoproteinDnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
X85960
36 DNMT1suppressorBAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
X85960
37 EEF1A1suppressorGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
X85960
38 EIF1AXoncoproteineIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1X85960
39 EIF2AK2oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Pkinase (PF00069, IPR000719): Protein kinase domain
X85960
40 EIF3AoncoproteinDUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
X85960
41 EIF3ConcoproteineIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399, IPR000717, SM00088): PCI domain
X85960
42 EIF3EoncoproteineIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
X85960
43 EIF3FsuppressorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
X85960
44 EIF3IoncoproteinISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
X85960
45 EIF4EoncoproteinIF4E (PF01652, IPR001040): Eukaryotic initiation factor 4EX85960
46 EIF4G1oncoproteinDUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
X85960
47 ELAC2oncoproteinSynthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit
Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
Lactamase_B_4 (PF13691, IPR027794): tRNase Z endonuclease
X85960
48 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)X85960
49 ERCC4oncoproteinERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
LUC7 (PF03194, IPR004882): LUC7 N_terminus
T2SSM_b (PF10741, IPR007690): Type II secretion system (T2SS), protein M subtype b
HHH_5 (PF14520): Helix-hairpin-helix domain
X85960
50 EXOC4oncoproteinDUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain
Vps51 (PF08700): Vps51/Vps67
X85960
51 FABP3suppressorLipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein familyX85960
52 FANCD2oncoproteinFancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nucleaseX85960
53 FBXO11oncoproteinTFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
X85960
54 FIP1L1oncoproteinFip1 (PF05182, IPR007854): Fip1 motif
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
Auts2 (PF15336): Autism susceptibility gene 2 protein
X85960
55 FMNL3oncoproteinDrf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
STAS_2 (PF13466, IPR002645): STAS domain
X85960
56 FSCN1oncoproteinFascin (PF06268, IPR022768): Fascin domainX85960
57 FUBP1oncoproteinDUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
X85960
58 GGHoncoproteinPeptidase_C26 (PF07722, IPR011697): Peptidase C26X85960
59 GMPSoncoproteinGATase (PF00117, IPR017926): Glutamine amidotransferase class-I
GMP_synt_C (PF00958, IPR001674): GMP synthase C terminal domain
NAD_synthase (PF02540, IPR022310): NAD synthase
X85960
60 GOT2oncoproteinAminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and IIX85960
61 GPHNoncoproteinMoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain
MoeA_C (PF03454, IPR005111): MoeA C-terminal region (domain IV)
MoeA_N (PF03453, IPR005110): MoeA N-terminal region (domain I and II)
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
X85960
62 GRNoncoproteinGranulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
X85960
63 GSE1oncoproteinCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DUF3736 (PF12540, IPR022207): Protein of unknown function (DUF3736)
AAA_11 (PF13086): AAA domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
X85960
64 GSPT1oncoproteinGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
X85960
65 HIP1oncoproteinANTH (PF07651, IPR011417): ANTH domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
X85960
66 HIST1H1ConcoproteinAmelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
X85960
67 HLTFsuppressorHIRAN (PF08797, IPR014905, SM00910): HIRAN domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
X85960
68 HMGB1oncoproteinHMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
X85960
69 HNRNPA2B1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)X85960
70 HNRNPA3oncoproteinIATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
X85960
71 HNRNPDoncoproteinCBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
X85960
72 HNRNPKoncoproteinROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
X85960
73 HOOK3oncoproteinHOOK (PF05622, IPR008636): HOOK proteinX85960
74 HSPA5oncoproteinHSP70 (PF00012, IPR013126): Hsp70 proteinX85960
75 HSPA8oncoproteinHSP70 (PF00012, IPR013126): Hsp70 proteinX85960
76 HSPA9oncoproteinHSP70 (PF00012, IPR013126): Hsp70 proteinX85960
77 HSPD1suppressorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin familyX85960
78 IDH1suppressorIso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenaseX85960
79 IDH2oncoproteinIso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenaseX85960
80 IGHG1oncoproteinC1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domainX85960
81 ILF3oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
X85960
82 INTS6suppressorVWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus
DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
X85960
83 IRF2BP2oncoproteinzf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Bd3614_N (PF14442, IPR025854): Bd3614-like deaminase N-terminal
X85960
84 KIF14oncoproteinFHA (PF00498, IPR000253, SM00240): FHA domain
LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
SdrG_C_C (PF10425, IPR011266): C-terminus of bacterial fibrinogen-binding adhesin
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Gluconate_2-dh3 (PF13618, IPR027056): Gluconate 2-dehydrogenase subunit 3
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
X85960
85 L1CAMoncoproteinfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
Bravo_FIGEY (PF13882, IPR026966): Bravo-like intracellular region
Ig_3 (PF13927): Immunoglobulin domain
X85960
86 LRRFIP1oncoproteinCENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3
LRRFIP (PF09738, IPR019139): LRRFIP family
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
Coilin_N (PF15862, IPR031722): Coilin N-terminus
X85960
87 MAD1L1suppressorMAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
X85960
88 MAP4oncoproteinSdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
X85960