Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins NR3C1 (from a repository: Fri Dec 2 21:56:52 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 157 The number (and %) of the onco-proteins 51 (32.48 %) The number (and %) of the tumor suppressors 29 (18.47 %) Total number of binary PPIs (saturation %) 1063 (8.68 %) The number (and %) of affected PPIs 157 (14.77 %) The number of possible different fusions 36 PPI diameter 2 PPI radius 1 The average degree of PPI 12.611 Assortativity coefficient -0.2360 The network average Clustering coefficient 0.520 The number (and %) of a zero Clustering coefficients 4 (2.55 %) The number (and %) of a zero Betweenness Centrality 17 (10.83 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: NR3C1	All fusions : AW975686; CB219071; DR980088; BU679196; AA649098; CB219072; BQ433097; AA730920;
Proteins found in more fusions	FYN (see 1 fusions); YWHAH (see 2 fusions); PIAS2 (see 2 fusions); PRKDC (see 3 fusions); NR2F2 (see 1 fusions); HMGB1/HMGB2 (see 1 fusions); SMARCC1 (see 2 fusions); EP300 (see 1 fusions); ZBTB16 (see 3 fusions); GRIP1 (see 2 fusions); TP53 (see 3 fusions); POU2F1 (see 1 fusions); HSP90AA1 (see 2 fusions); SFPQ (see 6 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); NFKB1 (see 2 fusions); NCOA1 (see 2 fusions); LCK (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); CALR (see 6 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); CD2AP (see 1 fusions); NEDD4L (see 3 fusions); RANBP9 (see 2 fusions); EGFR (see 2 fusions); POU2F2 (see 5 fusions); STUB1 (see 1 fusions); RACK1 (see 3 fusions); KAT5 (see 3 fusions); PML (see 4 fusions); NCL (see 3 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	NR3C1	parental protein	157	0.069	15984.767	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
2	ADA	interactor	3	0.667	0.500	A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase
3	ANLN	oncoprotein	5	0.400	4.333	Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus
4	ARPC5	interactor	4	0.667	1.667	P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
5	BAG1	oncoprotein	7	0.619	5.756	BAG (PF02179, IPR003103, SM00264): BAG domain Presenilin (PF01080, IPR001108): Presenilin ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
6	BRCC3	interactor	13	0.621	10.829	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
7	CALR	oncoprotein	8	0.381	10.817	Calreticulin (PF00262, IPR001580): Calreticulin family DDHD (PF02862, IPR004177, SM01127): DDHD domain
8	CCDC6	oncoprotein	11	0.455	18.256	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046) FAM199X (PF15814, IPR029672): Protein family FAM199X
9	CD2AP	protein found in more fusions	13	0.394	26.655	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
10	CD3G	interactor	2	1.000	0	ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
11	CD4	suppressor	9	0.500	7.152	ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
12	CEBPA	suppressor	17	0.375	31.445	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
13	CEBPB	oncoprotein	22	0.524	25.661	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
14	CENPB	interactor	2	1.000	0	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain CENP-B_N (PF04218, IPR007889): CENP-B N-terminal DNA-binding domain DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain
15	CERK	interactor	1	0	0	DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
16	COPS6	interactor	11	0.311	21.215	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
17	CREB1	oncoprotein	19	0.458	35.148	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
18	CREBBP	suppressor	43	0.309	303.069	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
19	DAP3	interactor	5	0.833	0.400	DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3
20	DAXX	oncoprotein	17	0.483	26.302	Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
21	DCAF6	interactor	2	0	0	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain
22	DDX54	interactor	3	0.667	0.667	DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23	DNAJC7	interactor	11	0.491	16.944	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
24	DNMT3L	interactor	8	0.750	1.139	CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
25	DYNLT1	interactor	4	0.500	2.667	Tctex-1 (PF03645, IPR005334): Tctex-1 family
26	ECD	interactor	2	1.000	0	Bradykinin (PF06753, IPR009608): Bradykinin SGT1 (PF07093, IPR010770): SGT1 protein
27	EGFR	oncoprotein	26	0.257	140.463	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
28	ELAVL1	oncoprotein	38	0.119	454.442	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29	EP300	oncoprotein	40	0.314	239.123	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30	ETS2	suppressor	9	0.750	4.610	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
31	FGFR1OP	oncoprotein	4	0.667	0.500	FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain
32	FKBP4	interactor	6	0.800	0.869	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
33	FKBP5	interactor	6	0.600	4.202	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain
34	FOXJ2	interactor	6	0.533	3.708	SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain Spt20 (PF12090, IPR021950): Spt20 family Pro-rich (PF15240, IPR026086): Proline-rich
35	FOXL1	oncoprotein	5	0.400	4.500	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36	FTH1	interactor	6	0.600	3.500	Coat_F (PF07875, IPR012851): Coat F domain Ferritin (PF00210, IPR008331): Ferritin-like domain
37	FYN	oncoprotein	10	0.417	16.686	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
38	GAPVD1	interactor	6	0.600	3.738	RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
39	GNB1	interactor	5	0.600	3.000	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
40	GNB2	interactor	7	0.476	7.480	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
41	GRIP1	protein found in more fusions	9	0.893	0.515	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
42	HDAC1	suppressor	48	0.261	479.672	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
43	HDAC2	suppressor	26	0.333	103.900	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
44	HDAC6	oncoprotein	16	0.295	35.509	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
45	HMGB1	oncoprotein	13	0.410	28.267	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
46	HMGB2	protein found in more fusions	6	0.533	4.133	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
47	HMOX2	interactor	4	0.500	3.000	Heme_oxygenase (PF01126, IPR016053): Heme oxygenase
48	HNRNPA1	interactor	20	0.281	86.435	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
49	HNRNPR	interactor	15	0.467	28.998	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
50	HNRNPU	interactor	13	0.359	33.979	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
51	HOXB1	interactor	3	0.667	0.500	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
52	HSP90AA1	oncoprotein	36	0.193	350.317	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
53	HSPA1A	interactor	12	0.455	17.971	HSP70 (PF00012, IPR013126): Hsp70 protein
54	HSPA4	interactor	23	0.285	114.745	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
55	HSPD1	suppressor	9	0.444	12.427	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
56	IDE	interactor	2	1.000	0	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
57	JUN	oncoprotein	33	0.329	156.460	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
58	KAT5	suppressor	20	0.491	31.794	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
59	KDM5A	suppressor	4	0.833	0.222	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain FRG1 (PF06229, IPR010414): FRG1-like domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
60	LARP7	interactor	9	0.750	3.586	Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif
61	LCK	oncoprotein	7	0.533	2.619	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
62	LRIF1	interactor	8	0.333	12.000	LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
63	MAFF	interactor	4	0.667	0.667	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
64	MAGEA11	interactor	8	0.381	10.733	MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
65	MBOAT1	interactor	2	1.000	0	MBOAT (PF03062, IPR004299): MBOAT, membrane-bound O-acyltransferase family CBP_BcsF (PF11120, IPR019995): Cellulose biosynthesis protein BcsF DUF3329 (PF11808, IPR021766): Domain of unknown function (DUF3329)
66	MDM2	oncoprotein	31	0.340	132.447	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
67	MED1	interactor	12	0.436	15.217	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
68	MED14	interactor	6	0.733	1.800	Med14 (PF08638, IPR013947): Mediator complex subunit MED14
69	MED25	interactor	6	0.700	1.122	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
70	MSX2	interactor	5	0.500	1.015	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
71	MTA2	interactor	13	0.551	16.159	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
72	NCL	protein found in more fusions	10	0.556	7.579	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
73	NCOA1	oncoprotein	28	0.348	119.452	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
74	NCOA2	oncoprotein	11	0.582	11.569	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
75	NCOA3	oncoprotein	17	0.544	19.713	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
76	NCOA4	suppressor	3	0.667	1.000	ARA70 (PF12489, IPR022174): Nuclear coactivator
77	NCOA6	oncoprotein	21	0.416	45.775	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
78	NCOR1	oncoprotein	27	0.376	101.478	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
79	NCOR2	oncoprotein	21	0.519	32.598	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
80	NEDD4L	suppressor	11	0.333	22.856	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
81	NFKB1	suppressor	26	0.357	88.788	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
82	NFKB2	oncoprotein	6	0.700	1.400	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Death (PF00531, IPR000488, SM00005): Death domain RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
83	NR0B1	interactor	3	1.000	0	zf-C4_ClpX (PF06689, IPR010603, SM00994): ClpX C4-type zinc finger Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat
84	NR1H3	interactor	8	0.464	6.827	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
85	NR2E3	interactor	2	1.000	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
86	NR2F2	protein found in more fusions	5	0.500	2.000	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
87	NR2F6	oncoprotein	4	0.667	1.333	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
88	NR3C2	oncoprotein	16	0.300	55.629	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
89	NR4A1	suppressor	18	0.418	34.952	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
90	NRIP1	oncoprotein	11	0.345	19.800	ALMT (PF11744, IPR020966): Aluminium activated malate transporter NRIP1_repr_1 (PF15687, IPR031405): Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 (PF15688, IPR031406): Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 (PF15689, IPR031407): Nuclear receptor-interacting protein 1 repression 3 NRIP1_repr_4 (PF15690, IPR031408): Nuclear receptor-interacting protein 1 repression 4
91	ONECUT1	suppressor	2	1.000	0	CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
92	OSGEP	interactor	3	1.000	0	Peptidase_M22 (PF00814, IPR000905): Glycoprotease family
93	PBX1	oncoprotein	9	0.472	11.717	PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
94	PIAS2	protein found in more fusions	10	0.556	11.262	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
95	PML	suppressor	30	0.411	81.820	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
96	POLR1D	interactor	3	0.667	0.400	RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
97	POU1F1	interactor	6	0.800	1.122	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2
98	POU2F1	protein found in more fusions	11	0.378	16.298	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
99	POU2F2	oncoprotein	6	0.500	2.800	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
100	PPARG	suppressor	44	0.218	515.572	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
101	PPARGC1A	interactor	16	0.500	21.771	Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1
102	PPID	interactor	6	0.600	3.733	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
103	PPP5C	interactor	7	0.667	2.721	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat
104	PRKDC	protein found in more fusions	15	0.451	19.009	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
105	PSMC3IP	interactor	1	0	0	Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
106	PTGES3	interactor	13	0.470	20.950	CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
107	PTMS	interactor	5	0.500	3.333	Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
108	RABEP2	interactor	7	0.952	0.250	Rab5-bind (PF09311, IPR015390): Rabaptin-like protein Rabaptin (PF03528, IPR018514): Rabaptin
109	RACK1	suppressor	10	0.333	14.752	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
110	RAD54L2	interactor	4	0.833	0.250	SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
111	RAD9A	oncoprotein	3	0.667	0.500	Rad9 (PF04139, IPR007268): Rad9
112	RAF1	oncoprotein	16	0.324	48.005	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
113	RAN	oncoprotein	5	0.500	2.167	Ras (PF00071, IPR001806, SM00173): Ras family
114	RANBP9	suppressor	11	0.333	16.178	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
115	RBM14	suppressor	9	0.389	10.077	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
116	RELA	oncoprotein	33	0.361	146.659	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
117	RPS6KA5	interactor	9	0.528	4.068	Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
118	RXRB	interactor	6	0.600	3.571	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
119	SET	oncoprotein	8	0.571	4.967	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
120	SF3A1	interactor	12	0.394	19.886	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
121	SFN	suppressor	12	0.364	19.989	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
122	SFPQ	oncoprotein	20	0.298	59.222	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
123	SGTA	interactor	3	1.000	0	TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_17 (PF13431): Tetratricopeptide repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
124	SMAD3	oncoprotein	29	0.339	134.180	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
125	SMARCA2	suppressor	18	0.510	27.797	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
126	SMARCA4	suppressor	24	0.464	45.453	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
127	SMARCC1	suppressor	18	0.515	22.087	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
128	SMARCD1	interactor	11	0.655	6.807	ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
129	SMARCE1	interactor	13	0.577	8.478	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
130	SRA1	interactor	6	0.467	4.869	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
131	SRC	oncoprotein	13	0.485	15.168	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
132	STAT3	suppressor	28	0.302	138.719	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
133	STAT5B	oncoprotein	5	0.667	1.167	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
134	STUB1	suppressor	21	0.353	69.160	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
135	SUMO1	interactor	15	0.505	16.793	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
136	SVIL	interactor	7	0.333	11.452	Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
137	TADA2A	interactor	10	0.400	15.331	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
138	TBP	interactor	20	0.409	56.207	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
139	TDG	interactor	8	0.786	1.111	Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
140	TEAD2	interactor	7	0.286	9.530	TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
141	TGFB1I1	interactor	3	1.000	0	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
142	TMF1	interactor	1	0	0	Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) NHase_beta (PF02211, IPR024690): Nitrile hydratase beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain PilW (PF16074, IPR032092): Type IV Pilus-assembly protein W BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
143	TP53	suppressor	59	0.186	846.268	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
144	TRIM24	suppressor	8	0.571	2.192	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) zf-MYND (PF01753, IPR002893): MYND finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 Imm68 (PF15583, IPR028276): Immunity protein 68 SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
145	TRIM28	protein found in more fusions	24	0.316	95.157	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
146	TSG101	suppressor	11	0.533	10.575	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain
147	TTC5	interactor	2	1.000	0	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat Abi_C (PF14355, IPR026001): Abortive infection C-terminus TTC5_OB (PF16669, IPR032076): Tetratricopeptide repeat protein 5 OB fold domain
148	TXN	oncoprotein	8	0.357	12.037	Thioredoxin (PF00085, IPR013766): Thioredoxin
149	TXN2	interactor	5	0.500	3.667	Thioredoxin (PF00085, IPR013766): Thioredoxin
150	UBE2I	interactor	34	0.314	180.939	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
151	UBE2L3	interactor	10	0.417	7.998	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
152	YWHAH	protein found in more fusions	5	0.833	0.667	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
153	ZBTB16	suppressor	16	0.505	20.788	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
154	ZBTB20	interactor	5	0.400	2.563	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GTPase_binding (PF09027, IPR015116): GTPase binding zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
155	ZBTB3	interactor	4	0.667	0.444	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
156	ZBTB9	interactor	3	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type PRIMA1 (PF16101): Proline-rich membrane anchor 1
157	ZNF496	interactor	3	0.667	0.182	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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