Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins NR3C1 (from a repository: Fri Dec 2 21:56:52 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PNG file PDF file SVG file SIF file XML file GraphML file

Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 157 The number (and %) of the onco-proteins 51 (32.48 %) The number (and %) of the tumor suppressors 29 (18.47 %) Total number of binary PPIs (saturation %) 1063 (8.68 %) The number (and %) of affected PPIs 157 (14.77 %) The number of possible different fusions 36 PPI diameter 2 PPI radius 1 The average degree of PPI 12.611 Assortativity coefficient -0.2360 The network average Clustering coefficient 0.520 The number (and %) of a zero Clustering coefficients 4 (2.55 %) The number (and %) of a zero Betweenness Centrality 17 (10.83 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: NR3C1	All fusions : AW975686; BQ433097; CB219071; DR980088; AA730920; BU679196; AA649098; CB219072;
Proteins found in more fusions	FYN (see 1 fusions); YWHAH (see 2 fusions); PIAS2 (see 2 fusions); PRKDC (see 3 fusions); NR2F2 (see 1 fusions); HMGB1/HMGB2 (see 1 fusions); SMARCC1 (see 2 fusions); EP300 (see 1 fusions); ZBTB16 (see 3 fusions); GRIP1 (see 2 fusions); TP53 (see 3 fusions); POU2F1 (see 1 fusions); HSP90AA1 (see 2 fusions); SFPQ (see 6 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); NFKB1 (see 2 fusions); NCOA1 (see 2 fusions); LCK (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); CALR (see 6 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); CD2AP (see 1 fusions); NEDD4L (see 3 fusions); RANBP9 (see 2 fusions); EGFR (see 2 fusions); POU2F2 (see 5 fusions); STUB1 (see 1 fusions); RACK1 (see 3 fusions); KAT5 (see 3 fusions); PML (see 4 fusions); NCL (see 3 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	NR3C1	parental protein	157	0.069	15984.767	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
2	ADA	interactor	3	0.667	0.500	A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase
3	ANLN	oncoprotein	5	0.400	4.333	Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus
4	ARPC5	interactor	4	0.667	1.667	P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
5	BAG1	oncoprotein	7	0.619	5.756	BAG (PF02179, IPR003103, SM00264): BAG domain Presenilin (PF01080, IPR001108): Presenilin ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
6	BRCC3	interactor	13	0.621	10.829	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
7	CALR	oncoprotein	8	0.381	10.817	Calreticulin (PF00262, IPR001580): Calreticulin family DDHD (PF02862, IPR004177, SM01127): DDHD domain
8	CCDC6	oncoprotein	11	0.455	18.256	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046) FAM199X (PF15814, IPR029672): Protein family FAM199X
9	CD2AP	protein found in more fusions	13	0.394	26.655	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
10	CD3G	interactor	2	1.000	0	ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
11	CD4	suppressor	9	0.500	7.152	ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
12	CEBPA	suppressor	17	0.375	31.445	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
13	CEBPB	oncoprotein	22	0.524	25.661	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
14	CENPB	interactor	2	1.000	0	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain CENP-B_N (PF04218, IPR007889): CENP-B N-terminal DNA-binding domain DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain
15	CERK	interactor	1	0	0	DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
16	COPS6	interactor	11	0.311	21.215	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
17	CREB1	oncoprotein	19	0.458	35.148	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
18	CREBBP	suppressor	43	0.309	303.069	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
19	DAP3	interactor	5	0.833	0.400	DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3
20	DAXX	oncoprotein	17	0.483	26.302	Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
21	DCAF6	interactor	2	0	0	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain
22	DDX54	interactor	3	0.667	0.667	DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23	DNAJC7	interactor	11	0.491	16.944	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
24	DNMT3L	interactor	8	0.750	1.139	CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
25	DYNLT1	interactor	4	0.500	2.667	Tctex-1 (PF03645, IPR005334): Tctex-1 family
26	ECD	interactor	2	1.000	0	Bradykinin (PF06753, IPR009608): Bradykinin SGT1 (PF07093, IPR010770): SGT1 protein
27	EGFR	oncoprotein	26	0.257	140.463	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
28	ELAVL1	oncoprotein	38	0.119	454.442	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29	EP300	oncoprotein	40	0.314	239.123	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30	ETS2	suppressor	9	0.750	4.610	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
31	FGFR1OP	oncoprotein	4	0.667	0.500	FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain
32	FKBP4	interactor	6	0.800	0.869	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
33	FKBP5	interactor	6	0.600	4.202	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain
34	FOXJ2	interactor	6	0.533	3.708	SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain Spt20 (PF12090, IPR021950): Spt20 family Pro-rich (PF15240, IPR026086): Proline-rich
35	FOXL1	oncoprotein	5	0.400	4.500	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36	FTH1	interactor	6	0.600	3.500	Coat_F (PF07875, IPR012851): Coat F domain Ferritin (PF00210, IPR008331): Ferritin-like domain
37	FYN	oncoprotein	10	0.417	16.686	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
38	GAPVD1	interactor	6	0.600	3.738	RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
39	GNB1	interactor	5	0.600	3.000	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
40	GNB2	interactor	7	0.476	7.480	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
41	GRIP1	protein found in more fusions	9	0.893	0.515	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
42	HDAC1	suppressor	48	0.261	479.672	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
43	HDAC2	suppressor	26	0.333	103.900	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
44	HDAC6	oncoprotein	16	0.295	35.509	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
45	HMGB1	oncoprotein	13	0.410	28.267	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
46	HMGB2	protein found in more fusions	6	0.533	4.133	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
47	HMOX2	interactor	4	0.500	3.000	Heme_oxygenase (PF01126, IPR016053): Heme oxygenase
48	HNRNPA1	interactor	20	0.281	86.435	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
49	HNRNPR	interactor	15	0.467	28.998	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
50	HNRNPU	interactor	13	0.359	33.979	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
51	HOXB1	interactor	3	0.667	0.500	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
52	HSP90AA1	oncoprotein	36	0.193	350.317	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
53	HSPA1A	interactor	12	0.455	17.971	HSP70 (PF00012, IPR013126): Hsp70 protein
54	HSPA4	interactor	23	0.285	114.745	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
55	HSPD1	suppressor	9	0.444	12.427	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
56	IDE	interactor	2	1.000	0	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
57	JUN	oncoprotein	33	0.329	156.460	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
58	KAT5	suppressor	20	0.491	31.794	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
59	KDM5A	suppressor	4	0.833	0.222	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain FRG1 (PF06229, IPR010414): FRG1-like domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
60	LARP7	interactor	9	0.750	3.586	Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif
61	LCK	oncoprotein	7	0.533	2.619	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
62	LRIF1	interactor	8	0.333	12.000	LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
63	MAFF	interactor	4	0.667	0.667	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
64	MAGEA11	interactor	8	0.381	10.733	MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
65	MBOAT1	interactor	2	1.000	0	MBOAT (PF03062, IPR004299): MBOAT, membrane-bound O-acyltransferase family CBP_BcsF (PF11120, IPR019995): Cellulose biosynthesis protein BcsF DUF3329 (PF11808, IPR021766): Domain of unknown function (DUF3329)
66	MDM2	oncoprotein	31	0.340	132.447	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
67	MED1	interactor	12	0.436	15.217	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
68	MED14	interactor	6	0.733	1.800	Med14 (PF08638, IPR013947): Mediator complex subunit MED14
69	MED25	interactor	6	0.700	1.122	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
70	MSX2	interactor	5	0.500	1.015	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
71	MTA2	interactor	13	0.551	16.159	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
72	NCL	protein found in more fusions	10	0.556	7.579	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
73	NCOA1	oncoprotein	28	0.348	119.452	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
74	NCOA2	oncoprotein	11	0.582	11.569	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
75	NCOA3	oncoprotein	17	0.544	19.713	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
76	NCOA4	suppressor	3	0.667	1.000	ARA70 (PF12489, IPR022174): Nuclear coactivator
77	NCOA6	oncoprotein	21	0.416	45.775	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
78	NCOR1	oncoprotein	27	0.376	101.478	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
79	NCOR2	oncoprotein	21	0.519	32.598	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
80	NEDD4L	suppressor	11	0.333	22.856	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
81	NFKB1	suppressor	26	0.357	88.788	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
82	NFKB2	oncoprotein	6	0.700	1.400	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Death (PF00531, IPR000488, SM00005): Death domain RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
83	NR0B1	interactor	3	1.000	0	zf-C4_ClpX (PF06689, IPR010603, SM00994): ClpX C4-type zinc finger Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat
84	NR1H3	interactor	8	0.464	6.827	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
85	NR2E3	interactor	2	1.000	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
86	NR2F2	protein found in more fusions	5	0.500	2.000	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
87	NR2F6	oncoprotein	4	0.667	1.333	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
88	NR3C2	oncoprotein	16	0.300	55.629	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
89	NR4A1	suppressor	18	0.418	34.952	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
90	NRIP1	oncoprotein	11	0.345	19.800	ALMT (PF11744, IPR020966): Aluminium activated malate transporter NRIP1_repr_1 (PF15687, IPR031405): Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 (PF15688, IPR031406): Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 (PF15689, IPR031407): Nuclear receptor-interacting protein 1 repression 3 NRIP1_repr_4 (PF15690, IPR031408): Nuclear receptor-interacting protein 1 repression 4
91	ONECUT1	suppressor	2	1.000	0	CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
92	OSGEP	interactor	3	1.000	0	Peptidase_M22 (PF00814, IPR000905): Glycoprotease family
93	PBX1	oncoprotein	9	0.472	11.717	PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
94	PIAS2	protein found in more fusions	10	0.556	11.262	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
95	PML	suppressor	30	0.411	81.820	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
96	POLR1D	interactor	3	0.667	0.400	RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
97	POU1F1	interactor	6	0.800	1.122	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2
98	POU2F1	protein found in more fusions	11	0.378	16.298	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
99	POU2F2	oncoprotein	6	0.500	2.800	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
100	PPARG	suppressor	44	0.218	515.572	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
101	PPARGC1A	interactor	16	0.500	21.771	Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1
102	PPID	interactor	6	0.600	3.733	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
103	PPP5C	interactor	7	0.667	2.721	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat
104	PRKDC	protein found in more fusions	15	0.451	19.009	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
105	PSMC3IP	interactor	1	0	0	Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
106	PTGES3	interactor	13	0.470	20.950	CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
107	PTMS	interactor	5	0.500	3.333	Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
108	RABEP2	interactor	7	0.952	0.250	Rab5-bind (PF09311, IPR015390): Rabaptin-like protein Rabaptin (PF03528, IPR018514): Rabaptin
109	RACK1	suppressor	10	0.333	14.752	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
110	RAD54L2	interactor	4	0.833	0.250	SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
111	RAD9A	oncoprotein	3	0.667	0.500	Rad9 (PF04139, IPR007268): Rad9
112	RAF1	oncoprotein	16	0.324	48.005	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
113	RAN	oncoprotein	5	0.500	2.167	Ras (PF00071, IPR001806, SM00173): Ras family
114	RANBP9	suppressor	11	0.333	16.178	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
115	RBM14	suppressor	9	0.389	10.077	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
116	RELA	oncoprotein	33	0.361	146.659	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
117	RPS6KA5	interactor	9	0.528	4.068	Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
118	RXRB	interactor	6	0.600	3.571	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
119	SET	oncoprotein	8	0.571	4.967	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
120	SF3A1	interactor	12	0.394	19.886	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
121	SFN	suppressor	12	0.364	19.989	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
122	SFPQ	oncoprotein	20	0.298	59.222	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
123	SGTA	interactor	3	1.000	0	TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_17 (PF13431): Tetratricopeptide repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
124	SMAD3	oncoprotein	29	0.339	134.180	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
125	SMARCA2	suppressor	18	0.510	27.797	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
126	SMARCA4	suppressor	24	0.464	45.453	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
127	SMARCC1	suppressor	18	0.515	22.087	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
128	SMARCD1	interactor	11	0.655	6.807	ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
129	SMARCE1	interactor	13	0.577	8.478	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
130	SRA1	interactor	6	0.467	4.869	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
131	SRC	oncoprotein	13	0.485	15.168	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
132	STAT3	suppressor	28	0.302	138.719	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
133	STAT5B	oncoprotein	5	0.667	1.167	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
134	STUB1	suppressor	21	0.353	69.160	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
135	SUMO1	interactor	15	0.505	16.793	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
136	SVIL	interactor	7	0.333	11.452	Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
137	TADA2A	interactor	10	0.400	15.331	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
138	TBP	interactor	20	0.409	56.207	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
139	TDG	interactor	8	0.786	1.111	Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
140	TEAD2	interactor	7	0.286	9.530	TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
141	TGFB1I1	interactor	3	1.000	0	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
142	TMF1	interactor	1	0	0	Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) NHase_beta (PF02211, IPR024690): Nitrile hydratase beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain PilW (PF16074, IPR032092): Type IV Pilus-assembly protein W BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
143	TP53	suppressor	59	0.186	846.268	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
144	TRIM24	suppressor	8	0.571	2.192	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) zf-MYND (PF01753, IPR002893): MYND finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 Imm68 (PF15583, IPR028276): Immunity protein 68 SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
145	TRIM28	protein found in more fusions	24	0.316	95.157	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
146	TSG101	suppressor	11	0.533	10.575	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain
147	TTC5	interactor	2	1.000	0	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat Abi_C (PF14355, IPR026001): Abortive infection C-terminus TTC5_OB (PF16669, IPR032076): Tetratricopeptide repeat protein 5 OB fold domain
148	TXN	oncoprotein	8	0.357	12.037	Thioredoxin (PF00085, IPR013766): Thioredoxin
149	TXN2	interactor	5	0.500	3.667	Thioredoxin (PF00085, IPR013766): Thioredoxin
150	UBE2I	interactor	34	0.314	180.939	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
151	UBE2L3	interactor	10	0.417	7.998	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
152	YWHAH	protein found in more fusions	5	0.833	0.667	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
153	ZBTB16	suppressor	16	0.505	20.788	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
154	ZBTB20	interactor	5	0.400	2.563	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GTPase_binding (PF09027, IPR015116): GTPase binding zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
155	ZBTB3	interactor	4	0.667	0.444	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
156	ZBTB9	interactor	3	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type PRIMA1 (PF16101): Proline-rich membrane anchor 1
157	ZNF496	interactor	3	0.667	0.182	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑