1 |
NLK | parental protein | 56 | 0.067 | 2469.200 | Pkinase (PF00069, IPR000719): Protein kinase domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
2 |
ASGR1 | interactor | 1 | 0 | 0 | Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
3 |
ATXN1 | protein found in more fusions | 5 | 0.500 | 3.000 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term |
4 |
BACH1 | interactor | 3 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 |
5 |
CCP110 | interactor | 3 | 0.667 | 1.000 | DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) IFT20 (PF14931, IPR028172): Intraflagellar transport complex B, subunit 20 CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus CALM_bind (PF16025): Calcium-dependent calmodulin binding |
6 |
CEP97 | interactor | 2 | 1.000 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat |
7 |
CNOT11 | interactor | 3 | 0.667 | 0.667 | DUF2363 (PF10155, IPR019312): Uncharacterized conserved protein (DUF2363) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
8 |
CNOT2 | interactor | 5 | 0.500 | 4.667 | NOT2_3_5 (PF04153, IPR007282): NOT2 / NOT3 / NOT5 family |
9 |
CNOT3 | suppressor | 2 | 1.000 | 0 | NOT2_3_5 (PF04153, IPR007282): NOT2 / NOT3 / NOT5 family Not3 (PF04065, IPR007207): Not1 N-terminal domain, CCR4-Not complex component Pheromone (PF08015, IPR012597): Fungal mating-type pheromone |
10 |
CREBBP | oncoprotein | 15 | 0.363 | 42.967 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
11 |
CTNNB1 | oncoprotein | 11 | 0.418 | 23.267 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
12 |
CUL1 | oncoprotein | 11 | 0.311 | 25.433 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
13 |
ELAVL1 | oncoprotein | 14 | 0.282 | 48.333 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
14 |
FAM222A | interactor | 1 | 0 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1992 (PF09350, IPR018961): Domain of unknown function (DUF1992) FAM222A (PF15258, IPR029340): Protein family of FAM222A |
15 |
FAM222B | interactor | 1 | 0 | 0 | FAM222A (PF15258, IPR029340): Protein family of FAM222A |
16 |
FBXW4 | oncoprotein | 2 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box |
17 |
FBXW5 | interactor | 5 | 0.400 | 5.000 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like |
18 |
FOXO1 | oncoprotein | 7 | 0.733 | 1.900 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
19 |
FOXO3 | oncoprotein | 8 | 0.643 | 4.233 | Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
20 |
FOXO4 | oncoprotein | 6 | 0.800 | 1.300 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
21 |
GRN | oncoprotein | 2 | 1.000 | 0 | Granulin (PF00396, IPR000118, SM00277): Granulin Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain |
22 |
HIPK2 | oncoprotein | 11 | 0.400 | 20.367 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
23 |
KPNB1 | protein found in more fusions | 7 | 0.533 | 4.467 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat |
24 |
KRTAP10-3 | interactor | 6 | 0.700 | 3.000 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
25 |
KRTAP4-2 | interactor | 4 | 1.000 | 0 | Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
26 |
KRTAP5-6 | interactor | 4 | 1.000 | 0 | NA |
27 |
KRTAP5-9 | interactor | 4 | 1.000 | 0 | Ery_res_leader2 (PF08057, IPR012559): Erythromycin resistance leader peptide |
28 |
LEF1 | oncoprotein | 6 | 0.533 | 5.833 | CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
29 |
MAP3K7 | oncoprotein | 6 | 0.400 | 5.500 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
30 |
MDM2 | oncoprotein | 11 | 0.444 | 18.167 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
31 |
MYB | oncoprotein | 7 | 0.429 | 10.067 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
32 |
MYBL1 | oncoprotein | 3 | 1.000 | 0 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
33 |
MYBL2 | oncoprotein | 5 | 0.667 | 1.000 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
34 |
PASK | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain PAS_8 (PF13188, IPR000014): PAS domain PAS_9 (PF13426, IPR000014): PAS domain |
35 |
PKM | oncoprotein | 3 | 1.000 | 0 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
36 |
QRICH1 | interactor | 3 | 1.000 | 0 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
37 |
RANBP2 | oncoprotein | 7 | 0.533 | 4.633 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
38 |
RANGAP1 | protein found in more fusions | 4 | 1.000 | 0 | RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain SDA1 (PF05285, IPR007949): SDA1 LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
39 |
RCHY1 | oncoprotein | 4 | 1.000 | 0 | C1_2 (PF03107, IPR004146): C1 domain zf-CHY (PF05495, IPR008913): CHY zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zinc_ribbon_6 (PF14599): Zinc-ribbon |
40 |
RNF219 | interactor | 4 | 0.667 | 1.667 | CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
41 |
SDR16C5 | interactor | 1 | 0 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
42 |
SHANK2 | interactor | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH3_2 (PF07653, IPR011511): Variant SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
43 |
SKI | oncoprotein | 6 | 0.600 | 2.067 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
44 |
SKP2 | oncoprotein | 7 | 0.476 | 6.467 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
45 |
SMAD4 | oncoprotein | 11 | 0.422 | 18.100 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
46 |
STAT5A | oncoprotein | 4 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
47 |
TAB2 | oncoprotein | 3 | 1.000 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain DivIC (PF04977, IPR007060): Septum formation initiator Mnd1 (PF03962, IPR005647): Mnd1 family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
48 |
TCF7L2 | oncoprotein | 6 | 0.533 | 5.333 | CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
49 |
TLE3 | interactor | 5 | 0.500 | 2.500 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
50 |
TNKS1BP1 | interactor | 3 | 1.000 | 0 | Tankyrase_bdg_C (PF15327, IPR032764): Tankyrase binding protein C terminal domain |
51 |
TP53 | oncoprotein | 12 | 0.382 | 26.867 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
52 |
TRPS1 | interactor | 1 | 0 | 0 | Rubredoxin (PF00301, IPR024935): Rubredoxin zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type GATA (PF00320, IPR000679, SM00401): GATA zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_7 (PF15269): Zinc-finger |
53 |
UBAP2L | interactor | 3 | 0.667 | 1.000 | CUE (PF02845, IPR003892, SM00546): CUE domain DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2 UBA_4 (PF14555): UBA-like domain Comm (PF15957, IPR031878): Commissureless |
54 |
USP4 | oncoprotein | 5 | 0.667 | 2.000 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
55 |
WDCP | interactor | 1 | 0 | 0 | DUF4613 (PF15390, IPR028041): Domain of unknown function (DUF4613) |
56 |
ZHX3 | interactor | 3 | 1.000 | 0 | NUFIP1 (PF10453, IPR019496): Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain TerB_C (PF15615, IPR028932): TerB-C domain |