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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)282
The number (and %) of the onco-proteins90 (31.91 %)
The number (and %) of the tumor suppressors30 (10.64 %)
Total number of binary PPIs (saturation %)1153 (2.91 %)
The number (and %) of affected PPIs282 (24.46 %)
The number of possible different fusions40
PPI diameter2
PPI radius1
The average degree of PPI7.511
Assortativity coefficient-0.3038
The network average Clustering coefficient0.481
The number (and %) of a zero Clustering coefficients62 (21.99 %)
The number (and %) of a zero Betweenness Centrality111 (39.36 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NEDD4 All fusions
: BF815723;
Proteins found in more fusions ABL2 (see 2 fusions); SYK (see 1 fusions); MAP3K2 (see 2 fusions); EPS15 (see 1 fusions); HSF1 (see 3 fusions); CUL1 (see 3 fusions); RAC1 (see 1 fusions); FYN (see 1 fusions); UBE2D2 (see 2 fusions); SMURF2 (see 1 fusions); THOC1 (see 3 fusions); SMARCC1 (see 2 fusions); NUDT21 (see 2 fusions); MAP3K5 (see 1 fusions); UBE2E1 (see 2 fusions); UBC (see 1 fusions); SFTPC (see 1 fusions); FGFR2 (see 3 fusions); NEDD4 (see 1 fusions); URI1 (see 3 fusions); RNF11 (see 1 fusions); LUC7L2 (see 2 fusions); HNRNPUL1 (see 1 fusions); GABARAP (see 2 fusions); BMPR1A (see 1 fusions); MARK2 (see 2 fusions); SGK1 (see 2 fusions); YY1 (see 2 fusions); HNRNPL (see 2 fusions); IMPDH2 (see 2 fusions); ERBB3 (see 2 fusions); PRPF8 (see 3 fusions); POLR2E (see 2 fusions); EGFR (see 2 fusions); POLR2A (see 2 fusions); FGFR1 (see 2 fusions); KCNAB2 (see 1 fusions); CBLB (see 4 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NEDD4parental protein2820.02069819.340Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
2 ABCB1oncoprotein21.0000ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
3 ABCG1interactor100ABC2_membrane (PF01061, IPR013525): ABC-2 type transporter
ABC_tran (PF00005, IPR003439): ABC transporter
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
4 ABL1oncoprotein190.33365.340Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
5 ABL2oncoprotein80.7621.530Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NHS (PF15273, IPR024845): NHS-like
6 ADRB2interactor120.56410.1407tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
7 AKT1oncoprotein270.206191.465PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
8 AKT3oncoprotein100PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
9 AMOToncoprotein80.6195.019FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
10 AMOTL1interactor41.0000NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Presenilin (PF01080, IPR001108): Presenilin
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
11 AMPD2interactor31.0000A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase
12 ANKRD13Dinteractor80.32117.833UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
GPCR_chapero_1 (PF11904, IPR021832): GPCR-chaperone
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
13 ANXA13interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
14 ANXA9interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
15 AP1G2interactor21.0000Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
16 ARID1Asuppressor60.6672.967ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
17 ARRB1interactor250.233161.229Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
18 ARRB2interactor220.32098.505Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
19 ARRDC1interactor60.4675.267Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
20 ARRDC3interactor70.5243.702Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
21 ASPSCR1oncoprotein31.0000DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
22 AURKCinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
23 BAIAP2interactor60.5003.733IMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
24 BECN1suppressor50.5002.400APG6 (PF04111, IPR007243): Autophagy protein Apg6
Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain
BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
25 BMPR1Asuppressor51.0000Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
26 BRCA2suppressor40.6672.000BRCA-2_helical (PF09169, IPR015252): BRCA2, helical
BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1
BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
BRCA2 (PF00634, IPR002093): BRCA2 repeat
Tower (PF09121, IPR015205): Tower
27 BTRConcoprotein260.227181.929WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
28 C11orf63interactor100ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein
DUF4591 (PF15261, IPR027968): Domain of unknown function (DUF4591)
29 CADoncoprotein80.42910.352Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
30 CALCOCO1interactor21.0000CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
31 CAMK1Dinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase
32 CAMK4interactor100DUF1103 (PF06513, IPR009484): Repeat of unknown function (DUF1103)
Pkinase (PF00069, IPR000719): Protein kinase domain
33 CAMKK2oncoprotein21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
34 CBLBoncoprotein140.37229.869Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
35 CCNHoncoprotein31.00005_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
36 CDC25Concoprotein31.0000M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
37 CDK5oncoprotein70.5336.167Pkinase (PF00069, IPR000719): Protein kinase domain
38 CDK5R1oncoprotein21.0000CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein
39 CFTRsuppressor31.0000ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
40 CLIC2interactor100MKT1_C (PF12246, IPR022039): Temperature dependent protein affecting M2 dsRNA replication
GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
41 CLK3interactor50.8330.400Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
42 CPSF1interactor31.0000CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
43 CPSF6interactor60.6004.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
44 CSNK1Dinteractor80.42910.675Pkinase (PF00069, IPR000719): Protein kinase domain
45 CUEDC1oncoprotein70.33313.667CUE (PF02845, IPR003892, SM00546): CUE domain
46 CUL1suppressor300.261197.115Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
47 CUL5suppressor220.32593.387Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
48 DCUN1D1interactor170.31655.137Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
49 DDX3Xsuppressor130.32132.619DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
50 DDX54interactor21.0000DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
51 DHX30interactor60.7333.333Bombolitin (PF08096, IPR012534): Bombolitin family
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
52 DIAPH1interactor21.0000APG6 (PF04111, IPR007243): Autophagy protein Apg6
Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain
Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
53 DMDsuppressor40.6671.333CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
54 DVL1interactor90.5715.419DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
55 DYRK4interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
56 EBAG9oncoprotein100DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395)
57 EGFRoncoprotein470.138711.914Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
58 EPHA5interactor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
59 EPRSinteractor70.4298.633GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal
tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
60 EPS15oncoprotein160.33346.836Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
61 ERBB3oncoprotein100.6116.995Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
62 ERBB4suppressor70.7331.376Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
63 ERGoncoprotein80.3939.450Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
64 ERMNinteractor100CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
65 FAM189A2interactor70.33313.667CD20 (PF04103, IPR007237): CD20-like family
66 FAM189Binteractor31.0000CD20 (PF04103, IPR007237): CD20-like family
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family
67 FBXL15interactor50.7001.050LRV (PF01816, IPR004830): Leucine rich repeat variant
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
68 FBXL18interactor41.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
69 FESoncoprotein31.0000FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
70 FGF12oncoprotein100FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
71 FGF21interactor100FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
72 FGFR1oncoprotein60.5004.167I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
73 FGFR2oncoprotein40.6670.667Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
74 FKBP3interactor50.7001.154FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
75 FLT1oncoprotein100C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
76 FLT4interactor21.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
77 FYNoncoprotein150.26447.252Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
78 GABARAPsuppressor41.0000Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
79 GABARAPL1interactor50.5004.667Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
80 GABARAPL2interactor60.4008.667Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
81 GBAinteractor50.6002.167Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain
Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain
82 GGA3interactor50.7001.352Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
83 GJA1suppressor80.3819.186Connexin43 (PF03508, IPR013124): Gap junction alpha-1 protein (Cx43)
Connexin (PF00029, IPR013092, SM00037): Connexin
SieB (PF14163, IPR025982): Super-infection exclusion protein B
84 GLIS3interactor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
85 GRB10oncoprotein110.49115.276BPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
86 GRIA1interactor100ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
87 GRIN2Asuppressor40.8330.286ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
NMDAR2_C (PF10565, IPR018884): N-methyl D-aspartate receptor 2B3 C-terminus
88 GRIN2Doncoprotein100ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
MatE (PF01554, IPR002528): MatE
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
NMDAR2_C (PF10565, IPR018884): N-methyl D-aspartate receptor 2B3 C-terminus
PRIMA1 (PF16101): Proline-rich membrane anchor 1
89 GRK4interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
90 GRK7interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
91 GUCD1interactor100Guanylate_cyc_2 (PF09778, IPR018616): Guanylylate cyclase
92 HGSinteractor280.196246.817FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
93 HMCESinteractor21.0000SRAP (PF02586, IPR003738): SOS response associated peptidase (SRAP)
94 HNRNPKoncoprotein210.37470.668ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
95 HNRNPLprotein found in more fusions80.8571.133RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
96 HNRNPUinteractor260.283156.936CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
97 HNRNPUL1protein found in more fusions80.5714.019Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
98 HSF1protein found in more fusions40.6670.500DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
99 IFITM3interactor21.0000CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
100 IGF1Roncoprotein90.5007.212fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
101 IL2RBoncoprotein21.0000IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
102 IL2RGoncoprotein30.6671.000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
103 IMPDH2protein found in more fusions50.6670.750IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
104 IRS1interactor100.46712.825CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
105 IRS2oncoprotein50.8000.667CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
106 ISG15suppressor80.35713.133ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 JUNoncoprotein120.43617.991bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
108 KCNAB1interactor30.6671.000Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
109 KCNAB2protein found in more fusions31.0000Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
110 KCNQ1interactor100Ion_trans (PF00520, IPR005821): Ion transport protein
KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel
Sensor (PF13796, IPR025828): Putative sensor
111 KIF26Binteractor31.0000Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Microtub_bd (PF16796, IPR031852): Microtubule binding
112 KIFC3oncoprotein50.5003.000Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
113 LAPTM4Ainteractor21.0000Mtp (PF03821, IPR004687): Golgi 4-transmembrane spanning transporter
WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
114 LAPTM4Binteractor21.0000Mtp (PF03821, IPR004687): Golgi 4-transmembrane spanning transporter
115 LAPTM5oncoprotein70.5244.583Mtp (PF03821, IPR004687): Golgi 4-transmembrane spanning transporter
116 LATS1suppressor130.26943.546Cas_Cas6 (PF01881, IPR010156): CRISPR associated protein Cas6
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
117 LATS2suppressor120.38224.633Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
118 LDLRAD4interactor90.38918.952Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615)
119 LITAFsuppressor40.8330.400zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
120 LRRK1interactor40.6670.333Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
121 LUC7L2protein found in more fusions80.5715.900LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
122 MAP2oncoprotein60.6002.800MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
RII_binding_1 (PF10522, IPR018459): RII binding domain
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
123 MAP3K2protein found in more fusions40.6671.000PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
124 MAP3K3oncoprotein60.4005.400PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
125 MAP3K5oncoprotein70.7332.452Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
126 MAP4K5interactor21.0000CNH (PF00780, IPR001180, SM00036): CNH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
127 MAPKAPK3interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
128 MARK2protein found in more fusions80.28611.317DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
129 MARK4oncoprotein50.5003.333KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
130 MDM2oncoprotein360.180349.797Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
131 MGRN1interactor60.4003.933zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
132 MLANAinteractor100MLANA (PF14991, IPR029242): Protein melan-A
133 MOB3Ainteractor31.0000Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
134 MRPL19interactor31.0000Ribosomal_L19 (PF01245, IPR001857): Ribosomal protein L19
EABR (PF12180, IPR022008): TSG101 and ALIX binding domain of CEP55
135 MTMR4interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
136 MYCNoncoprotein100HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
137 N4BP3oncoprotein100Fez1 (PF06818): Fez1
YqzE (PF14038, IPR025622): YqzE-like protein
138 NDFIP1interactor70.38110.286DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370)
WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
Comm (PF15957, IPR031878): Commissureless
139 NDFIP2interactor70.3819.986DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370)
140 NFE2interactor31.0000bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase
141 NHP2interactor100Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
142 NSRP1interactor100Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF2040 (PF09745, IPR018612): Coiled-coil domain-containing protein 55 (DUF2040)
Macoilin (PF09726, IPR019130): Transmembrane protein
PepSY_2 (PF13670, IPR025711): Peptidase propeptide and YPEB domain
143 NTRK1oncoprotein660.0891658.673I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
144 NUDT21protein found in more fusions50.6671.286NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
145 PARP16interactor100PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
146 PAX7oncoprotein100PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Pax7 (PF12360, IPR022106): Paired box protein 7
147 PDCD6IPinteractor120.34524.117BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
148 PDGFRBoncoprotein100.5836.671I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
Ig_3 (PF13927): Immunoglobulin domain
TonB_N (PF16031): TonB N-terminal region
149 PDLIM7interactor50.5002.619LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
150 PKN2interactor50.6671.667C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
151 PLK1suppressor110.25535.249Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
152 PLK2suppressor30.6670.667Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
153 PMEPA1oncoprotein100SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide
154 POLR2Aprotein found in more fusions180.36061.893RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
155 POLR2Binteractor120.57613.921RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
156 POLR2Cinteractor110.53312.602RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
157 POLR2Eprotein found in more fusions130.47022.000RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain
RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain
158 POLR2Minteractor60.9330.250GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
159 POLR3Ainteractor70.8570.936RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
160 PPARGsuppressor90.5366.782zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
161 PRKG2interactor100CpeT (PF06206, IPR010404): CpeT/CpcT family (DUF1001)
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
FeoB_N (PF02421, IPR011619): Ferrous iron transport protein B
Pkinase (PF00069, IPR000719): Protein kinase domain
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
162 PRKXinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
163 PRPF8oncoprotein80.6194.019PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
164 PRR16interactor100EzrA (PF06160, IPR010379): Septation ring formation regulator, EzrA
DUF4589 (PF15252, IPR027997): Domain of unknown function (DUF4589)
165 PRRG1interactor100Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
RCR (PF12273, IPR020999): Chitin synthesis regulation, resistance to Congo red
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family
166 PSMD4interactor120.42420.487UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
167 PTCH1suppressor40.6672.000Patched (PF02460, IPR003392): Patched family
168 PTENsuppressor150.21962.263DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
169 PYM1interactor30.6670.667CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
Mago-bind (PF09282, IPR015362): Mago binding
AAA_23 (PF13476): AAA domain
170 RAC1oncoprotein70.4006.536Ras (PF00071, IPR001806, SM00173): Ras family
171 RAD51AP1interactor100RAD51_interact (PF15696, IPR031419): RAD51 interacting motif
172 RAF1oncoprotein170.27567.252Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
173 RANBP10interactor100LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
174 RAP2Aoncoprotein40.5003.000Ras (PF00071, IPR001806, SM00173): Ras family
175 RAPGEF2interactor40.6672.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
176 RAPGEF6interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
177 RASGEF1Ainteractor100RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
178 RASL11Boncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
Transferase (PF02458, IPR003480): Transferase family
179 RBCK1interactor90.5006.508GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
180 RBX1oncoprotein150.37429.002zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
181 RFT1interactor21.0000Rft-1 (PF04506, IPR007594): Rft protein
182 RNF11protein found in more fusions180.27955.903zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
183 RNF7oncoprotein90.5713.994zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
184 RPAP2interactor80.6794.433NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
RPAP2_Rtr1 (PF04181, IPR007308): Rtr1/RPAP2 family
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
185 RPAP3interactor90.6945.269TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
186 RPS3Ainteractor110.52714.770Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
187 RPS6KA3interactor50.6002.567Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
188 RPS6KA4interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
189 RPS6KB1interactor90.42911.256Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
190 RPSAinteractor51.0000Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
191 RTF1interactor30.6670.182K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Plus-3 (PF03126, IPR004343): Plus-3 domain
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
YL1 (PF05764, IPR008895): YL1 nuclear protein
AAA_23 (PF13476): AAA domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
192 RUVBL1oncoprotein100.41713.769TIP49 (PF06068, IPR010339): TIP49 C-terminus
193 SAAL1interactor21.0000NA
194 SAMSN1interactor100SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SLY (PF12485, IPR021090): Lymphocyte signaling adaptor protein
195 SAV1oncoprotein50.8001.333WW (PF00397, IPR001202, SM00456): WW domain
196 SCAMP3interactor60.7332.067SCAMP (PF04144, IPR007273): SCAMP family
197 SCN5Ainteractor100Ion_trans (PF00520, IPR005821): Ion transport protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
Na_trans_cytopl (PF11933, IPR024583): Cytoplasmic domain of voltage-gated Na+ ion channel
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
198 SCN8Ainteractor100ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
Ion_trans (PF00520, IPR005821): Ion transport protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Na_trans_cytopl (PF11933, IPR024583): Cytoplasmic domain of voltage-gated Na+ ion channel
TMEM51 (PF15345, IPR029265): Transmembrane protein 51
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
199 SCNN1Ainteractor40.8330.667ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
200 SCNN1Boncoprotein60.4677.067ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
201 SCNN1Ginteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
202 SEPT9oncoprotein30.6671.000Septin (PF00735, IPR000038): Septin
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
203 SFTPCprotein found in more fusions200BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain
SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide
204 SGK1oncoprotein70.4008.067Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
205 SGK2interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
206 SHTN1interactor31.0000Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
VIT1 (PF01988, IPR008217): VIT family
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
207 SIVA1interactor31.0000Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
208 SKILsuppressor70.7333.333c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
209 SKP1oncoprotein120.45520.660Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
210 SLC11A2interactor30.6670.500Nramp (PF01566, IPR001046): Natural resistance-associated macrophage protein
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
211 SLC12A3interactor100AA_permease (PF00324, IPR004841): Amino acid permease
AA_permease_N (PF08403, IPR013612): Amino acid permease N-terminal
SLC12 (PF03522, IPR018491): Solute carrier family 12
212 SLC23A2interactor100Xan_ur_permease (PF00860, IPR006043): Permease family
213 SLC38A3interactor100Aa_trans (PF01490, IPR004758): Transmembrane amino acid transporter protein
214 SLC5A7interactor100SSF (PF00474, IPR001734): Sodium:solute symporter family
DUF2244 (PF10003, IPR019253): Integral membrane protein (DUF2244)
215 SLC6A3oncoprotein30.6670.500SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family
216 SLC9A1interactor30.6671.000DUF1427 (PF07235, IPR009872): Protein of unknown function (DUF1427)
LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
217 SMAD1interactor140.52619.067MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
218 SMAD2suppressor240.253128.707MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
219 SMAD3oncoprotein250.261129.205MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
220 SMAD5interactor70.8571.083MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
221 SMAD6interactor70.8102.000MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
222 SMAD7interactor100.57811.233MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
223 SMARCC1suppressor90.5368.317SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
224 SMOoncoprotein21.0000Frizzled (PF01534, IPR000539): Frizzled/Smoothened family membrane region
Fz (PF01392, IPR020067, SM00063): Fz domain
225 SMURF2protein found in more fusions250.236160.813C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
226 SNCAinteractor150.26453.741Synuclein (PF01387, IPR001058): Synuclein
227 SP140Linteractor21.0000C1_2 (PF03107, IPR004146): C1 domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain; Sp100 domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
228 SPANXN3interactor21.0000SPAN-X (PF07458, IPR010007): Sperm protein associated with nucleus, mapped to X chromosome
229 SPRY1interactor40.5002.333PAP1 (PF08601, IPR013910): Transcription factor PAP1
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
230 SPRY2suppressor60.5003.133KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
231 SRConcoprotein290.257190.881Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
232 SRMSinteractor100Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
233 SRSF7interactor70.6674.900RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
234 STK24interactor50.6671.667DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
235 STK25interactor40.6672.000DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
236 STK26interactor60.6003.667DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
237 STK31interactor100Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein
Pkinase (PF00069, IPR000719): Protein kinase domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
DUF4047 (PF13256, IPR025120): Domain of unknown function (DUF4047)
238 STK4oncoprotein90.32113.541Pkinase (PF00069, IPR000719): Protein kinase domain
Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
239 SULF1interactor100GDNF (PF02351, IPR016017, SM00907): GDNF/GAS1 domain
Sulfatase (PF00884, IPR000917): Sulfatase
DUF3740 (PF12548, IPR024609): Sulfatase protein
240 SYKsuppressor110.44413.290Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
241 SYT1interactor30.6670.333C2 (PF00168, IPR000008, SM00239): C2 domain
Comm (PF15957, IPR031878): Commissureless
242 TAF1Binteractor100Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
243 TBC1D7interactor30.6671.000RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
244 TBK1interactor120.41817.569DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
245 TCEANCinteractor21.0000Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
246 TCP11L1interactor100Tcp11 (PF05794, IPR008862): T-complex protein 11
247 TEAD2interactor100TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
248 THOC1protein found in more fusions31.0000Death (PF00531, IPR000488, SM00005): Death domain
efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor
249 THRAP3oncoprotein90.38918.582API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
250 TMEM171interactor30.6671.000TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
251 TMEM255Ainteractor21.0000FAM70 (PF14967, IPR028014): FAM70 protein
252 TMEM51interactor21.0000WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
TMEM51 (PF15345, IPR029265): Transmembrane protein 51
253 TMEM52Binteractor30.6671.000LSR (PF05624, IPR008664): Lipolysis stimulated receptor (LSR)
TMEM52 (PF14979): Transmembrane 52
254 TMEM92interactor30.6671.000WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
255 TNIKinteractor100CNH (PF00780, IPR001180, SM00036): CNH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499)
CNDH2_M (PF16869): PF16858
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
256 TNK2interactor100.5288.836CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GTPase_binding (PF09027, IPR015116): GTPase binding
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
UBA_4 (PF14555): UBA-like domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
257 TOM1oncoprotein70.5715.733GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
258 TOM1L2suppressor40.8330.286GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
259 TP73suppressor60.6001.900P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
260 TRIM44interactor100Agouti (PF05039, IPR007733, SM00792): Agouti protein
CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
Herpes_UL17 (PF04559, IPR007640): Herpesvirus UL17 protein
SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
261 TRIM52interactor100BUD22 (PF09073, IPR015158): BUD22
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Fer2 (PF00111, IPR001041): 2Fe-2S iron-sulfur cluster binding domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
262 TRPV6oncoprotein100Ion_trans (PF00520, IPR005821): Ion transport protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
263 TSG101suppressor200.240102.159APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
264 TSTA3interactor21.0000Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
NICE-3 (PF07406, IPR010876): NICE-3 protein
Polysacc_synt_2 (PF02719, IPR003869): Polysaccharide biosynthesis protein
265 TTYH2interactor100Tweety (PF04906, IPR006990): Tweety
266 TTYH3interactor30.6671.000Tweety (PF04906, IPR006990): Tweety
267 UBAP2Linteractor50.5003.400CUE (PF02845, IPR003892, SM00546): CUE domain
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2
UBA_4 (PF14555): UBA-like domain
Comm (PF15957, IPR031878): Commissureless
268 UBCprotein found in more fusions510.155794.533ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
269 UBE2D1interactor180.33850.444UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
270 UBE2D2oncoprotein190.34061.186UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
271 UBE2D3interactor150.27537.725UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
272 UBE2E1protein found in more fusions60.5002.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
273 UBE2L3interactor130.34826.904UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
274 UBE2Minteractor90.6792.915UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
275 UBOX5interactor70.4673.041U-box (PF04564, IPR003613, SM00504): U-box domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
276 URI1protein found in more fusions70.6004.583CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
Prefoldin (PF02996, IPR004127): Prefoldin subunit
DUF3835 (PF12927, IPR024325): Domain of unknown function (DUF3835)
SCAPER_N (PF16501, IPR032446): S phase cyclin A-associated protein in the endoplasmic reticulum
277 WBP1interactor21.0000WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
278 WBP2interactor100GRAM (PF02893, IPR004182, SM00568): GRAM domain
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
279 WEE1interactor40.5001.333Pkinase (PF00069, IPR000719): Protein kinase domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
280 YES1oncoprotein90.33315.952Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
YdjC (PF04794, IPR006879): YdjC-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
281 YOD1interactor21.0000OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
282 YY1protein found in more fusions130.30331.668zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail

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