Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins NDUFA3 (from a repository: Tue Sep 11 03:52:22 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)18 (40.00 %)
The number (and %) of affected PPIs9 (50.00 %)
The number of possible different fusions1
PPI diameter2
PPI radius1
The average degree of PPI3.000
Assortativity coefficient-0.5774
The network average Clustering coefficient0.417
The number (and %) of a zero Clustering coefficients5 (50.00 %)
The number (and %) of a zero Betweenness Centrality9 (90.00 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions NDUFS3 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NDUFA3parental protein90.16760.000NADHdh_A3 (PF14987, IPR026626): NADH dehydrogenase 1 alpha subcomplex subunit 3
2 ECSITinteractor51.0000ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein
3 GAL3ST1interactor100Rhabdo_M1 (PF03342, IPR005010): Rhabdovirus M1 matrix protein (M1 polymerase-associated protein)
4 HLA-DPA1interactor100MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
5 NDUFA8interactor41.0000CHCH (PF06747, IPR010625): CHCH domain
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
Cdd1 (PF11731, IPR021725): Pathogenicity locus
6 NDUFS3protein found in more fusions51.0000Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
7 NRG1interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Neuregulin (PF02158, IPR002154): Neuregulin family
8 SLC18A1interactor100MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
9 THBS3oncoprotein200EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat
TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region
COMP (PF11598, IPR024665): Cartilage oligomeric matrix protein
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
10 TIMMDC1interactor41.0000Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family

B a c k    t o    T o p ⇑