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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)78
The number (and %) of the onco-proteins23 (29.49 %)
The number (and %) of the tumor suppressors3 (3.85 %)
Total number of binary PPIs (saturation %)255 (8.49 %)
The number (and %) of affected PPIs78 (30.59 %)
The number of possible different fusions15
PPI diameter2
PPI radius1
The average degree of PPI5.846
Assortativity coefficient-0.3241
The network average Clustering coefficient0.473
The number (and %) of a zero Clustering coefficients14 (17.95 %)
The number (and %) of a zero Betweenness Centrality27 (34.62 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NDEL1 All fusions
Proteins found in more fusions TUBG1 (see 1 fusions); APP (see 4 fusions); NDEL1 (see 1 fusions); NDE1 (see 3 fusions); CCDC88A (see 3 fusions); YWHAG (see 1 fusions); CENPF (see 1 fusions); LUC7L2 (see 2 fusions); AIMP2 (see 1 fusions); SYNE1 (see 2 fusions); IMMT (see 4 fusions); SNAP29 (see 1 fusions); NDC80 (see 1 fusions); PAFAH1B1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NDEL1parental protein780.0524886.821HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
2 AIMP2suppressor50.6671.667GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
3 ANK2interactor100Death (PF00531, IPR000488, SM00005): Death domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
4 APPprotein found in more fusions140.19260.233APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5 BMI1oncoprotein70.3339.000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
6 BORCS6interactor60.5335.233DUF2365 (PF10157, IPR019314): Uncharacterized conserved protein (DUF2365)
7 CCDC183interactor30.6670.333MRP-63 (PF14978, IPR016576): Mitochondrial ribosome protein 63
8 CCDC88Aprotein found in more fusions41.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
9 CCHCR1interactor110.22224.336HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
10 CCSER1interactor100RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
11 CCSER2interactor30.6670.667NA
12 CDK5oncoprotein40.6670.667Pkinase (PF00069, IPR000719): Protein kinase domain
13 CENPFoncoprotein200APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
IncA (PF04156, IPR007285): IncA protein
Propep_M14 (PF02244, IPR003146): Carboxypeptidase activation peptide
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Usp (PF00582, IPR006016): Universal stress protein family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
CENP-F_N (PF10481, IPR018463): Cenp-F N-terminal domain
CENP-F_C_Rb_bdg (PF10490, IPR018302): Rb-binding domain of kinetochore protein Cenp-F/LEK1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
14 CEP128interactor120.31836.667DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
15 CEP135interactor90.44413.067DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPD52 (PF04201, IPR007327): Tumour protein D52 family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
16 CEP152interactor40.8330.500bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
FAD-SLDH (PF12318, IPR024651): Membrane bound FAD containing D-sorbitol dehydrogenase
YtxH (PF12732, IPR024623): YtxH-like protein
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
17 CEP170interactor70.4299.133FHA (PF00498, IPR000253, SM00240): FHA domain
DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254)
CEP170_C (PF15308, IPR029300): CEP170 C-terminus
18 CEP63interactor80.39314.733DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa
19 CTR9interactor21.0000DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
Pap_E4 (PF02711, IPR003861): E4 protein
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
20 CWF19L2interactor50.4002.583CwfJ_C_1 (PF04677, IPR006768): Protein similar to CwfJ C-terminus 1
CwfJ_C_2 (PF04676, IPR006767): Protein similar to CwfJ C-terminus 2
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
MRI (PF15325, IPR028278): Modulator of retrovirus infection
21 DCTN2interactor90.46413.233Dynamitin (PF04912): Dynamitin
22 DISC1interactor170.191102.400HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
23 DIXDC1interactor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
SlyX (PF04102, IPR007236): SlyX
DIX (PF00778, IPR001158, SM00021): DIX domain
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
24 DTNBinteractor60.5003.583EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
SOGA (PF11365, IPR027881): Protein SOGA
25 DYNC1H1interactor100.40022.000AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1
DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1
AAA_7 (PF12775): P-loop containing dynein motor region D3
MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor
AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4
AAA_9 (PF12781): ATP-binding dynein motor region D5
26 DYNC1I1interactor50.8001.333CDC45 (PF02724, IPR003874): CDC45-like protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2
AviRa (PF11599, IPR024268): RRNA methyltransferase AviRa
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
27 DYNLT1interactor50.5004.000Tctex-1 (PF03645, IPR005334): Tctex-1 family
28 GOLGA2interactor70.3816.219ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
29 IMMTprotein found in more fusions40.6670.500Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
30 KALRNoncoprotein21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Spectrin (PF00435, IPR002017): Spectrin repeat
UPF0302 (PF08864, IPR014963): UPF0302 domain
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
HAD_2 (PF13419, IPR023214): Haloacid dehalogenase-like hydrolase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
31 KATNA1interactor60.6004.333AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ABC_tran (PF00005, IPR003439): ABC transporter
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
AAA_22 (PF13401, IPR003593): AAA domain
32 KATNB1interactor60.8001.000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Katanin_con80 (PF13925, IPR028021): con80 domain of Katanin
33 KIFC3oncoprotein120.29133.086Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
34 KRT40interactor110.23631.386Filament (PF00038, IPR001664): Intermediate filament protein
UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
35 LMNB1interactor30.6671.000Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
36 LUC7L2protein found in more fusions60.6003.667LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
37 MAGEA11interactor31.0000MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
38 MBIPinteractor70.4008.667DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
39 MIS18Ainteractor60.4677.000Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
DUF2868 (PF11067, IPR021296): Protein of unknown function (DUF2868)
40 MLLT10oncoprotein31.0000SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
Tnp_zf-ribbon_2 (PF13842, IPR032718): DDE_Tnp_1-like zinc-ribbon
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
AP3D1 (PF06375): AP-3 complex subunit delta-1
41 MRC2interactor100Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381)
42 MTUS2suppressor120.18234.552DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
FAM184 (PF15665): Family with sequence similarity 184, A and B
43 NAP1L5interactor21.0000NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
SspB (PF04386, IPR007481): Stringent starvation protein B
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
44 NDC80protein found in more fusions40.6670.333DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family
SlyX (PF04102, IPR007236): SlyX
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
45 NDE1protein found in more fusions130.27339.819NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
46 NINLinteractor90.30621.286PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
47 PAFAH1B1suppressor130.36431.800LisH (PF08513, IPR013720, SM00667): LisH
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
48 PKP2interactor40.5003.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
49 SCARA3interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Flagellin_C (PF00700, IPR001029): Bacterial flagellin C-terminal helical region
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
50 SNAP29protein found in more fusions60.4003.900DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
V-SNARE_C (PF12352): Snare region anchored in the vesicle membrane C-terminus
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
51 SNAPC5interactor100SNAPc19 (PF15497, IPR029138): snRNA-activating protein complex subunit 19, SNAPc subunit 19
52 SNX6interactor21.0000PX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
53 SSX2IPinteractor110.31125.119ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
54 SYNE1oncoprotein50.6671.500Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
POX (PF07526, IPR006563, SM00574): Associated with HOX
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
THOC7 (PF05615, IPR008501): Tho complex subunit 7
TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
KASH (PF10541, IPR012315): Nuclear envelope localisation domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416)
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
55 TACC3oncoprotein30.6670.667TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
56 TRAF3IP3interactor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
57 TRIM27oncoprotein130.21241.786IncA (PF04156, IPR007285): IncA protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
58 TUBA1Aoncoprotein50.4004.500Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
59 TUBG1protein found in more fusions60.4005.333Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
60 USP2interactor70.4765.002UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
61 XPAoncoprotein21.0000XPA_C (PF05181, IPR022656): XPA protein C-terminus
XPA_N (PF01286, IPR022652): XPA protein N-terminal
MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
62 YWHAEoncoprotein60.4677.00014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
63 YWHAGprotein found in more fusions70.5336.16714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
64 ZNF10interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
65 ZNF17interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
66 ZNF180interactor21.0000C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
LIM (PF00412, IPR001781, SM00132): LIM domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Zn_ribbon_recom (PF13408, IPR025827): Recombinase zinc beta ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
67 ZNF197interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
68 ZNF211interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
69 ZNF230interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
70 ZNF260interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
71 ZNF264interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
72 ZNF417interactor70.3337.002A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
73 ZNF490interactor30.6670.250KRAB (PF01352, IPR001909, SM00349): KRAB box
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
74 ZNF544interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
XPA_N (PF01286, IPR022652): XPA protein N-terminal
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C4_ClpX (PF06689, IPR010603, SM00994): ClpX C4-type zinc finger
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
75 ZNF572interactor50.6001.686C1_2 (PF03107, IPR004146): C1 domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
76 ZNF599interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
77 ZNF844oncoprotein30.6670.250KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3268 (PF11672, IPR021686): zinc-finger-containing domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
78 ZNF91oncoprotein100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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