1 |
NCOA1 | parental protein | 101 | 0.120 | 5004.528 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
2 |
AHR | suppressor | 10 | 0.722 | 2.887 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAS_4 (PF08448, IPR013656): PAS fold |
3 |
ANIB1 | interactor | 2 | 1.000 | 0 | NA |
4 |
ANKRD11 | interactor | 3 | 1.000 | 0 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Pap_E4 (PF02711, IPR003861): E4 protein MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_11 (PF13086): AAA domain Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
5 |
AR | oncoprotein | 29 | 0.376 | 85.531 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
6 |
ARID1A | suppressor | 14 | 0.429 | 24.496 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
7 |
ARNT | oncoprotein | 6 | 0.867 | 0.619 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
8 |
ASCC1 | interactor | 5 | 0.900 | 0.154 | AKAP7_NLS (PF10469, IPR019510): AKAP7 2'5' RNA ligase-like domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
9 |
BCL3 | oncoprotein | 11 | 0.655 | 5.466 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
10 |
BRCA1 | suppressor | 26 | 0.420 | 69.348 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
11 |
CARM1 | oncoprotein | 17 | 0.449 | 24.292 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
12 |
CCND1 | oncoprotein | 12 | 0.636 | 6.065 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
13 |
CIITA | oncoprotein | 6 | 0.667 | 1.317 | NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
14 |
COPS5 | protein found in more fusions | 19 | 0.320 | 61.250 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
15 |
CREBBP | suppressor | 38 | 0.366 | 169.273 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
16 |
CXADR | protein found in more fusions | 3 | 1.000 | 0 | Syndecan (PF01034, IPR027789): Syndecan domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator Ig_3 (PF13927): Immunoglobulin domain |
17 |
EP300 | oncoprotein | 52 | 0.272 | 445.733 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
18 |
ESR1 | suppressor | 43 | 0.242 | 355.197 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
19 |
ESR2 | suppressor | 14 | 0.500 | 11.224 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
20 |
ESRRA | oncoprotein | 6 | 0.600 | 3.351 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
21 |
ESRRG | oncoprotein | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
22 |
ETS1 | oncoprotein | 15 | 0.648 | 12.604 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
23 |
ETS2 | suppressor | 10 | 0.844 | 1.172 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
24 |
EZH2 | suppressor | 10 | 0.417 | 8.080 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
25 |
FOS | oncoprotein | 20 | 0.456 | 36.709 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
26 |
FOXA2 | suppressor | 1 | 0 | 0 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region HNF_C (PF09354, IPR018533): HNF3 C-terminal domain TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
27 |
FOXO1 | suppressor | 11 | 0.644 | 4.825 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
28 |
GTF2B | interactor | 12 | 0.561 | 13.066 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
29 |
HIF1A | suppressor | 15 | 0.619 | 13.037 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
30 |
HNF1A | oncoprotein | 9 | 0.643 | 2.739 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
31 |
HNF4A | suppressor | 17 | 0.442 | 26.538 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
32 |
HNF4G | interactor | 2 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
33 |
HSPA2 | interactor | 3 | 1.000 | 0 | HSP70 (PF00012, IPR013126): Hsp70 protein |
34 |
HSPA5 | oncoprotein | 7 | 0.733 | 1.543 | HSP70 (PF00012, IPR013126): Hsp70 protein |
35 |
ITCH | interactor | 10 | 0.556 | 9.569 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
36 |
JUN | oncoprotein | 30 | 0.384 | 99.709 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
37 |
KANK2 | interactor | 4 | 1.000 | 0 | KN_motif (PF12075, IPR021939): KN motif Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor |
38 |
KAT2B | protein found in more fusions | 21 | 0.405 | 46.651 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
39 |
KCTD3 | interactor | 2 | 1.000 | 0 | BTB_2 (PF02214, IPR003131): BTB/POZ domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
40 |
NCOA2 | oncoprotein | 36 | 0.268 | 243.562 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
41 |
NCOA3 | oncoprotein | 44 | 0.247 | 381.641 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
42 |
NCOA6 | oncoprotein | 30 | 0.330 | 129.414 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
43 |
NCOR1 | oncoprotein | 32 | 0.306 | 152.688 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
44 |
NFKB1 | suppressor | 23 | 0.351 | 67.092 | Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
45 |
NKX2-1 | oncoprotein | 5 | 1.000 | 0 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4719 (PF15843, IPR031696): Domain of unknown function (DUF4719) |
46 |
NR1H2 | oncoprotein | 9 | 0.667 | 2.441 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
47 |
NR1H3 | interactor | 9 | 0.583 | 3.726 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
48 |
NR1H4 | interactor | 9 | 0.667 | 2.539 | LRV_FeS (PF05484, IPR008665): LRV protein FeS4 cluster zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
49 |
NR1I2 | suppressor | 10 | 0.467 | 7.460 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
50 |
NR1I3 | interactor | 6 | 0.733 | 0.751 | PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
51 |
NR2F6 | oncoprotein | 8 | 0.464 | 4.621 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
52 |
NR3C1 | protein found in more fusions | 28 | 0.348 | 104.753 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
53 |
NR3C2 | oncoprotein | 7 | 0.667 | 1.480 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
54 |
NR4A1 | suppressor | 14 | 0.571 | 10.086 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
55 |
NR5A1 | interactor | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
56 |
NR5A2 | interactor | 3 | 0.667 | 0.118 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
57 |
NR6A1 | interactor | 2 | 0 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
58 |
PAGR1 | interactor | 3 | 1.000 | 0 | PAXIP1_C (PF15364, IPR028213): PAXIP1-associated-protein-1 C term PTIP binding protein |
59 |
PGR | suppressor | 16 | 0.400 | 23.733 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
60 |
PPARA | suppressor | 10 | 0.600 | 4.607 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
61 |
PPARD | oncoprotein | 10 | 0.556 | 3.580 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
62 |
PPARG | suppressor | 25 | 0.409 | 59.109 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
63 |
PPARGC1A | interactor | 22 | 0.307 | 84.911 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
64 |
PRMT1 | interactor | 16 | 0.533 | 17.315 | Methyltransf_25 (PF13649): Methyltransferase domain |
65 |
RABGGTB | oncoprotein | 1 | 0 | 0 | Prenyltrans (PF00432, IPR001330): Prenyltransferase and squalene oxidase repeat |
66 |
RARA | oncoprotein | 20 | 0.363 | 47.988 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
67 |
RARB | suppressor | 5 | 0.500 | 2.067 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
68 |
RARG | oncoprotein | 7 | 0.476 | 3.521 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
69 |
RBBP6 | oncoprotein | 4 | 0.833 | 0.182 | DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936) DWNN (PF08783, IPR014891): DWNN domain Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region U-box (PF04564, IPR003613, SM00504): U-box domain SBF2 (PF12335, IPR022096): Myotubularin protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
70 |
RNF4 | interactor | 7 | 0.667 | 1.437 | Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger |
71 |
RORA | interactor | 4 | 0.500 | 0.804 | zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
72 |
RORB | interactor | 2 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
73 |
RXRA | oncoprotein | 33 | 0.282 | 178.652 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
74 |
RXRB | interactor | 13 | 0.231 | 21.697 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
75 |
SF1 | protein found in more fusions | 6 | 0.600 | 3.000 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
76 |
SMAD3 | oncoprotein | 26 | 0.493 | 47.360 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
77 |
SMARCA4 | suppressor | 24 | 0.377 | 71.057 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
78 |
SMARCC1 | suppressor | 17 | 0.550 | 15.218 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
79 |
SMARCE1 | interactor | 16 | 0.425 | 27.014 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
80 |
SNW1 | protein found in more fusions | 13 | 0.576 | 11.054 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
81 |
SRF | interactor | 10 | 0.583 | 8.663 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
82 |
STAT3 | suppressor | 19 | 0.438 | 28.144 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
83 |
STAT5A | suppressor | 12 | 0.564 | 6.047 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
84 |
STAT6 | oncoprotein | 11 | 0.655 | 3.726 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT6_C (PF14596, IPR028187): STAT6 C-terminal |
85 |
SYTL2 | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 |
86 |
TBP | interactor | 19 | 0.490 | 28.598 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
87 |
TEAD1 | interactor | 2 | 1.000 | 0 | TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family |
88 |
TEAD2 | interactor | 2 | 1.000 | 0 | TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family |
89 |
THRA | suppressor | 13 | 0.439 | 18.420 | C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
90 |
THRB | suppressor | 14 | 0.410 | 14.212 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
91 |
TP53 | suppressor | 38 | 0.321 | 211.997 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
92 |
TRIM21 | interactor | 5 | 0.500 | 1.122 | DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
93 |
TRIM24 | suppressor | 14 | 0.346 | 13.123 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) zf-MYND (PF01753, IPR002893): MYND finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 Imm68 (PF15583, IPR028276): Immunity protein 68 SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 |
94 |
TRIP11 | oncoprotein | 2 | 1.000 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1529 (PF07485, IPR011094): Domain of Unknown Function (DUF1259) DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) ZapB (PF06005, IPR009252): Cell division protein ZapB ERM (PF00769, IPR011259): Ezrin/radixin/moesin family NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF3138 (PF11336, IPR021485): Protein of unknown function (DUF3138) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
95 |
TRIP4 | interactor | 13 | 0.500 | 12.279 | ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type |
96 |
UBE2L3 | interactor | 9 | 0.286 | 11.610 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
97 |
UBR5 | protein found in more fusions | 9 | 0.464 | 7.801 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
98 |
VCP | protein found in more fusions | 16 | 0.362 | 36.614 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
99 |
VDR | suppressor | 19 | 0.582 | 19.696 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
100 |
WDHD1 | interactor | 2 | 1.000 | 0 | PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
101 |
YWHAQ | interactor | 9 | 0.528 | 6.297 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |