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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)119
The number (and %) of the onco-proteins34 (28.57 %)
The number (and %) of the tumor suppressors21 (17.65 %)
Total number of binary PPIs (saturation %)824 (11.74 %)
The number (and %) of affected PPIs119 (14.44 %)
The number of possible different fusions17
PPI diameter2
PPI radius1
The average degree of PPI13.143
Assortativity coefficient-0.2462
The network average Clustering coefficient0.568
The number (and %) of a zero Clustering coefficients6 (5.04 %)
The number (and %) of a zero Betweenness Centrality26 (21.85 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MSN All fusions
Proteins found in more fusions HLA-B (see 2 fusions); TKT (see 5 fusions); U2AF2 (see 2 fusions); SLC9A3R1 (see 2 fusions); CALR (see 6 fusions); TNFRSF1A (see 3 fusions); CD2AP (see 1 fusions); SELPLG (see 2 fusions); EWSR1 (see 2 fusions); FAXC (see 2 fusions); GSS (see 1 fusions); EZR (see 2 fusions); MCM2 (see 1 fusions); PAFAH1B1 (see 1 fusions); HSPB1 (see 4 fusions); VCL (see 2 fusions); JUP/MYH9 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MSNparental protein1190.0968322.761DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
2 ABCE1interactor140.32128.192ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 ACAA2interactor140.56015.927Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4 AHCYinteractor130.43919.671AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
5 AKR1B1suppressor110.7455.187Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
6 ARHGDIAinteractor280.308165.557Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
7 ASNSoncoprotein170.36853.529Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
8 ATIConcoprotein150.45728.801AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
9 BIDoncoprotein140.85911.000BID (PF06393, IPR010479): BH3 interacting domain (BID)
10 BRCA1suppressor110.48911.526BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
11 CALRoncoprotein180.50721.120Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
12 CALUinteractor80.7142.141EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
13 CAPN2interactor120.54518.951Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
14 CASP10interactor131.0000DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
15 CASP8suppressor131.0000DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
16 CD2APprotein found in more fusions51.0000SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
17 CD44suppressor70.5244.840VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
18 CD46oncoprotein21.0000Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
DUF3188 (PF11384, IPR021524): Protein of unknown function (DUF3188)
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
19 CD81interactor90.50010.267Tetraspannin (PF00335, IPR018499): Tetraspanin family
20 CDK11Boncoprotein31.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
21 CDK2suppressor350.237237.218Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
22 CTNNB1oncoprotein140.36336.802Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
23 DCPSinteractor120.47018.833DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
24 DHX15interactor160.42536.147DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
25 DUTinteractor140.44021.551dUTPase (PF00692, IPR008180): dUTPase
26 EIF5AL1interactor40.6670.297EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
27 ELAVL1oncoprotein220.29081.719RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
28 ENO1oncoprotein300.356131.624Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
29 ENO2interactor210.48637.889Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
30 EWSR1oncoprotein270.326106.283RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
31 EZRprotein found in more fusions580.1691046.121DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
32 FABP5interactor140.63716.851Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
33 FADDsuppressor121.0000Death (PF00531, IPR000488, SM00005): Death domain
DED (PF01335, IPR001875, SM00031): Death effector domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
34 FASsuppressor150.76914.467Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
35 FASLGinteractor140.75817.786PAP_PilO (PF06864, IPR009663): Pilin accessory protein (PilO)
TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
36 FAXCprotein found in more fusions200GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
GST_N_4 (PF17172): Glutathione S-transferase N-terminal domain
37 FHsuppressor150.47627.844Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
38 FKBP2interactor60.9330.222FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
39 FN1oncoprotein250.36788.465fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
40 GDI1interactor80.5007.146GDI (PF00996, IPR018203): GDP dissociation inhibitor
41 GINS3interactor90.52810.119Sld5 (PF05916, IPR021151): GINS complex protein
42 GSSprotein found in more fusions100.6397.271GSH_synth_ATP (PF03917, IPR005615): Eukaryotic glutathione synthase, ATP binding domain
43 GTF3C4interactor31.0000TFIIIC_delta (PF12657, IPR024761): Transcription factor IIIC subunit delta N-term
zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex
44 H2AFXsuppressor150.47620.711Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
45 HADHAinteractor60.6670.9423HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
46 HLA-Boncoprotein70.4005.467MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
47 HNRNPA1interactor270.345114.568RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
48 HSD17B10interactor230.41970.799adh_short (PF00106, IPR002198): short chain dehydrogenase
49 HSPA4interactor140.38526.219Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
50 HSPA4Linteractor90.6114.342HSP70 (PF00012, IPR013126): Hsp70 protein
51 HSPA5oncoprotein240.33687.252HSP70 (PF00012, IPR013126): Hsp70 protein
52 HSPB1oncoprotein170.40826.201HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
53 HSPE1interactor230.37972.555Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
54 HSPH1oncoprotein110.7273.430HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
55 ICAM1oncoprotein30.6670.167Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
56 ICAM2interactor21.0000ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
SecE (PF00584, IPR001901): SecE/Sec61-gamma subunits of protein translocation complex
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
57 ICAM3interactor21.0000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
58 IGSF8oncoprotein41.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
59 IMPA2interactor50.6670.500Inositol_P (PF00459, IPR000760): Inositol monophosphatase family
60 ISG15suppressor160.30840.875ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
61 ISYNA1interactor90.5838.805NAD_binding_5 (PF07994, IPR002587): Myo-inositol-1-phosphate synthase
62 ITGA4interactor210.43250.536FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
63 JUPsuppressor100.5337.998Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
64 LCP1oncoprotein50.8000.333CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
65 MAPK10suppressor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
66 MAPK8oncoprotein160.69520.115DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
67 MCM2oncoprotein350.340173.744AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
68 ME1interactor21.0000malic (PF00390, IPR012301): Malic enzyme, N-terminal domain
Malic_M (PF03949, IPR012302, SM00919): Malic enzyme, NAD binding domain
69 MYH9suppressor170.35344.093IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
70 MYO19interactor50.7001.467IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
71 NAE1interactor110.60010.355ThiF (PF00899, IPR000594): ThiF family
72 NCF1interactor40.6671.000p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
73 NCF4interactor21.0000PX (PF00787, IPR001683, SM00312): PX domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
74 NOTCH2suppressor100Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
75 NSFL1Cinteractor110.6559.005SEP (PF08059, IPR012989, SM00553): SEP domain
UBX (PF00789, IPR001012, SM00166): UBX domain
UBA_4 (PF14555): UBA-like domain
76 P4HBinteractor210.48936.214Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
77 PAFAH1B1suppressor120.58210.113LisH (PF08513, IPR013720, SM00667): LisH
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
78 PAFAH1B2oncoprotein110.47316.379Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
79 PAPSS1interactor130.55118.584APS_kinase (PF01583, IPR002891): Adenylylsulphate kinase
ATP-sulfurylase (PF01747, IPR024951): ATP-sulfurylase
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
PUA_2 (PF14306, IPR025980): PUA-like domain
80 PDHA1interactor80.5366.375E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
81 PDIA4interactor190.40954.900Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
82 PFASinteractor70.6195.300AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
83 PGDoncoprotein110.43612.9436PGD (PF00393, IPR006114): 6-phosphogluconate dehydrogenase, C-terminal domain
NAD_binding_2 (PF03446, IPR006115): NAD binding domain of 6-phosphogluconate dehydrogenase
84 PGK1interactor190.48027.157PGK (PF00162, IPR001576): Phosphoglycerate kinase
85 PGK2interactor40.8330.143PGK (PF00162, IPR001576): Phosphoglycerate kinase
86 PLS1interactor60.6004.083CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
87 PLS3interactor110.6008.584CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
88 PPP1R2interactor110.52715.186IPP-2 (PF04979, IPR007062): Protein phosphatase inhibitor 2 (IPP-2)
89 PTMAoncoprotein130.51317.279Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
90 PTPN1suppressor21.0000Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
91 RAP1GDS1oncoprotein160.46735.010Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
92 RCN1interactor100.6224.311EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
93 RHOAsuppressor150.68626.633Ras (PF00071, IPR001806, SM00173): Ras family
94 S100A16interactor100S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
95 SELLinteractor21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
MWFE (PF15879, IPR017384): NADH-ubiquinone oxidoreductase MWFE subunit
96 SELPLGprotein found in more fusions200EVI2A (PF05399, IPR008608): Ectropic viral integration site 2A protein (EVI2A)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF4689 (PF15755, IPR031499): Domain of unknown function (DUF4689)
97 SIRT7interactor250.243123.968DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
98 SLC9A3R1suppressor50.8330.333EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
99 SPNinteractor21.0000BatA (PF07584, IPR024163): Aerotolerance regulator N-terminal
MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK
100 SPTAN1oncoprotein110.49114.520EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
101 SRCAPinteractor100AT_hook (PF02178, IPR017956, SM00384): AT hook motif
HSA (PF07529, IPR014012, SM00573): HSA
RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
102 STIP1interactor250.45367.011TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): WTAP/Mum2p family
103 STK24interactor70.6003.933DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
104 TAGLN2interactor270.41684.601Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
105 TATDN1interactor130.62811.679TatD_DNase (PF01026, IPR001130): TatD related DNase
106 TERF1interactor170.24250.244TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
107 TKTprotein found in more fusions300.40492.324Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
108 TNFRSF10Bsuppressor121.0000Death (PF00531, IPR000488, SM00005): Death domain
RskA (PF10099, IPR018764): Anti-sigma-K factor rskA
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
109 TNFRSF1Aoncoprotein140.8725.419Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
110 TRIM15suppressor31.0000Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
111 TSC1suppressor31.0000Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Hamartin (PF04388, IPR007483): Hamartin protein
112 TSPAN33interactor100Tetraspannin (PF00335, IPR018499): Tetraspanin family
113 TUBB3interactor80.28611.121Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
114 U2AF2protein found in more fusions270.34896.681RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
115 UCHL3interactor140.61510.341Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
116 VCAM1interactor170.45627.395C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
117 VCLoncoprotein230.31296.909Vinculin (PF01044, IPR006077): Vinculin family
118 VPS11interactor21.0000DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
VPS11_C (PF12451, IPR024763): Vacuolar protein sorting protein 11 C terminal
TPR_11 (PF13414, IPR011990): TPR repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
119 WDR1interactor130.52616.723eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain

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