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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins MIEF1 (from a repository: Mon Dec 5 04:19:49 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins3 (27.27 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)19 (34.55 %)
The number (and %) of affected PPIs11 (57.89 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.182
Assortativity coefficient-0.3464
The network average Clustering coefficient0.246
The number (and %) of a zero Clustering coefficients7 (63.64 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MIEF1 All fusions
: BI086913;
Proteins found in more fusions UBQLN1 (see 2 fusions); YWHAG (see 1 fusions); MIEF1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MIEF1parental protein110.04485.000Mab-21 (PF03281, IPR024810): Mab-21 protein
2 AGTRAPinteractor200AGTRAP (PF06396, IPR009436, SM00805): Angiotensin II, type I receptor-associated protein (AGTRAP)
3 CDC42oncoprotein200Ras (PF00071, IPR001806, SM00173): Ras family
4 DNM1Linteractor40.6671.000Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
AAA_16 (PF13191): AAA ATPase domain
5 FIS1interactor31.0000Fis1_TPR_N (PF14852, IPR028058): Fis1 N-terminal tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
6 MAB21L2interactor100Mab-21 (PF03281, IPR024810): Mab-21 protein
7 MAGEA1interactor21.0000MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
8 UBQLN1protein found in more fusions200Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
9 WDFY2interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 YWHAGprotein found in more fusions20014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
11 ZNFX1interactor100zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil

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