Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins MIEF1 (from a repository: Mon Dec 5 04:19:49 2016)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins3 (27.27 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)19 (34.55 %)
The number (and %) of affected PPIs11 (57.89 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.182
Assortativity coefficient-0.3464
The network average Clustering coefficient0.246
The number (and %) of a zero Clustering coefficients7 (63.64 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)


List of the fusions

PPI for parental proteins: MIEF1 All fusions
: BI086913;
Proteins found in more fusions UBQLN1 (see 2 fusions); YWHAG (see 1 fusions); MIEF1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 MIEF1parental protein110.04485.000Mab-21 (PF03281, IPR024810): Mab-21 protein
2 AGTRAPinteractor200AGTRAP (PF06396, IPR009436, SM00805): Angiotensin II, type I receptor-associated protein (AGTRAP)
3 CDC42oncoprotein200Ras (PF00071, IPR001806, SM00173): Ras family
4 DNM1Linteractor40.6671.000Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
AAA_16 (PF13191): AAA ATPase domain
5 FIS1interactor31.0000Fis1_TPR_N (PF14852, IPR028058): Fis1 N-terminal tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
6 MAB21L2interactor100Mab-21 (PF03281, IPR024810): Mab-21 protein
7 MAGEA1interactor21.0000MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
8 UBQLN1protein found in more fusions200Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
9 WDFY2interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 YWHAGprotein found in more fusions20014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
11 ZNFX1interactor100zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil

B a c k    t o    T o p ⇑