1 |
MDH2 | parental protein | 49 | 0.147 | 1250.243 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
2 |
ATF2 | oncoprotein | 8 | 0.333 | 7.291 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
3 |
ATP5A1 | protein found in more fusions | 15 | 0.451 | 21.773 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
4 |
ATP5B | interactor | 18 | 0.340 | 63.197 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
5 |
CCDC8 | interactor | 8 | 0.762 | 1.869 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
6 |
CDK2 | suppressor | 13 | 0.394 | 21.377 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
7 |
CFL1 | interactor | 17 | 0.309 | 67.440 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
8 |
CLNS1A | interactor | 3 | 0.667 | 0.250 | Voldacs (PF03517): Regulator of volume decrease after cellular swelling |
9 |
COPS5 | protein found in more fusions | 9 | 0.464 | 7.636 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
10 |
CORO1C | oncoprotein | 7 | 0.381 | 5.198 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat |
11 |
COTL1 | oncoprotein | 2 | 1.000 | 0 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
12 |
CRYAB | oncoprotein | 5 | 0.833 | 0.667 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
13 |
CUL7 | protein found in more fusions | 17 | 0.358 | 42.913 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
14 |
DAZAP1 | interactor | 13 | 0.321 | 35.729 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) |
15 |
FH | suppressor | 4 | 0.500 | 1.167 | Lyase_1 (PF00206, IPR022761): Lyase FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus |
16 |
FN1 | oncoprotein | 14 | 0.308 | 38.941 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
17 |
FUS | suppressor | 14 | 0.505 | 18.686 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
18 |
GLRX2 | interactor | 1 | 0 | 0 | Glutaredoxin (PF00462, IPR002109): Glutaredoxin |
19 |
GRPEL1 | interactor | 4 | 0.667 | 0.333 | GrpE (PF01025, IPR000740): GrpE |
20 |
GRSF1 | interactor | 3 | 0.667 | 0.667 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence VWA_N2 (PF16164, IPR032361): VWA N-terminal |
21 |
HDAC5 | protein found in more fusions | 7 | 0.667 | 1.467 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
22 |
HUWE1 | oncoprotein | 15 | 0.330 | 41.352 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
23 |
IDH1 | suppressor | 5 | 0.500 | 2.900 | Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase |
24 |
IDH3A | interactor | 5 | 0.500 | 2.750 | Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase |
25 |
ITGA4 | interactor | 13 | 0.439 | 21.156 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
26 |
LDHAL6A | interactor | 3 | 1.000 | 0 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
27 |
METTL21B | interactor | 2 | 1.000 | 0 | Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase |
28 |
MRPS28 | interactor | 4 | 0.500 | 2.000 | MRP-S35 (PF10246, IPR019375): Mitochondrial ribosomal protein MRP-S35 |
29 |
NTRK1 | oncoprotein | 22 | 0.267 | 111.182 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
30 |
NUDC | interactor | 9 | 0.333 | 14.677 | CS (PF04969, IPR007052): CS domain D5_N (PF08706, IPR014818, SM00885): D5 N terminal like Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc. NuDC (PF16273, IPR032572): Nuclear distribution C domain |
31 |
OBSL1 | interactor | 12 | 0.509 | 10.588 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
32 |
PARK2 | suppressor | 9 | 0.393 | 9.619 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
33 |
PC | interactor | 3 | 1.000 | 0 | Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like (PF00682, IPR000891): HMGL-like PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain |
34 |
PCNA | oncoprotein | 15 | 0.330 | 33.456 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
35 |
PPME1 | protein found in more fusions | 5 | 0.833 | 0.333 | Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
36 |
PSMA3 | interactor | 11 | 0.467 | 15.086 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
37 |
PSMD4 | interactor | 10 | 0.511 | 14.519 | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
38 |
QSOX2 | interactor | 1 | 0 | 0 | Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain Evr1_Alr (PF04777, IPR017905): Erv1 / Alr family Thioredoxin (PF00085, IPR013766): Thioredoxin zf-HYPF (PF07503, IPR011125): HypF finger Thioredoxin_2 (PF13098, IPR012336): Thioredoxin-like domain |
39 |
RAB10 | oncoprotein | 6 | 0.667 | 2.008 | Ras (PF00071, IPR001806, SM00173): Ras family |
40 |
SDHA | suppressor | 6 | 0.600 | 2.436 | FAD_binding_2 (PF00890, IPR003953): FAD binding domain Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term |
41 |
SDHB | suppressor | 5 | 0.700 | 1.200 | Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain Fer4_17 (PF13534): 4Fe-4S dicluster domain |
42 |
SERPINH1 | interactor | 9 | 0.528 | 6.910 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
43 |
SOD1 | interactor | 10 | 0.389 | 17.400 | Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC) |
44 |
U2AF2 | protein found in more fusions | 10 | 0.528 | 7.808 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
45 |
UBE2L3 | interactor | 9 | 0.393 | 11.567 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
46 |
UFM1 | interactor | 4 | 0.833 | 0.333 | Ufm1 (PF03671, IPR005375): Ubiquitin fold modifier 1 protein |
47 |
VCAM1 | interactor | 9 | 0.528 | 6.977 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
48 |
WARS | interactor | 5 | 0.800 | 0.900 | tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
49 |
YKT6 | interactor | 1 | 0 | 0 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |