Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins MCM7 (from a repository: Sat Dec 3 23:22:56 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 151 The number (and %) of the onco-proteins 47 (31.13 %) The number (and %) of the tumor suppressors 15 (9.93 %) Total number of binary PPIs (saturation %) 1165 (10.29 %) The number (and %) of affected PPIs 151 (12.96 %) The number of possible different fusions 31 PPI diameter 2 PPI radius 1 The average degree of PPI 14.503 Assortativity coefficient -0.1883 The network average Clustering coefficient 0.517 The number (and %) of a zero Clustering coefficients 3 (1.99 %) The number (and %) of a zero Betweenness Centrality 20 (13.25 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: MCM7	All fusions : BF971291; T12299;
Proteins found in more fusions	STAU1 (see 2 fusions); L3MBTL1 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); LAMP2 (see 1 fusions); VHL (see 1 fusions); MYC (see 1 fusions); UBQLN1 (see 2 fusions); COPS5 (see 1 fusions); HDAC5 (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); CCND1 (see 1 fusions); RPA1 (see 1 fusions); VPS35 (see 2 fusions); SUZ12 (see 2 fusions); TRAF6 (see 1 fusions); APP (see 4 fusions); ORC2 (see 2 fusions); MCM7 (see 2 fusions); CRY2 (see 3 fusions); ATR (see 1 fusions); HSP90AB1 (see 1 fusions); VPS26A (see 1 fusions); BAG3 (see 4 fusions); MCM2 (see 1 fusions); POLR2A (see 2 fusions); EPAS1 (see 1 fusions); MAPRE2 (see 1 fusions); MIB1 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	MCM7	parental protein	151	0.085	13246.720	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
2	ACTR1A	interactor	10	0.622	5.696	Actin (PF00022, IPR004000, SM00268): Actin
3	AHSA1	interactor	13	0.474	19.763	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
4	AK8	interactor	2	1.000	0	ADK (PF00406, IPR000850): Adenylate kinase AAA_16 (PF13191): AAA ATPase domain
5	APP	protein found in more fusions	36	0.121	397.065	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6	ASB8	interactor	5	0.700	1.122	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
7	ASF1A	interactor	11	0.782	3.063	ASF1_hist_chap (PF04729, IPR006818): ASF1 like histone chaperone
8	ASF1B	interactor	13	0.679	7.787	ASF1_hist_chap (PF04729, IPR006818): ASF1 like histone chaperone
9	ATR	suppressor	8	0.619	3.543	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 THP2 (PF09432, IPR018557): Tho complex subunit THP2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat UME (PF08064, IPR012993, SM00802): UME (NUC010) domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT
10	ATRIP	interactor	7	0.571	4.856	Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
11	BAG3	oncoprotein	14	0.295	34.113	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
12	C14orf166	interactor	12	0.591	7.035	RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
13	C8orf34	interactor	2	0	0	Glycoprotein_G (PF00802, IPR000925): Pneumovirus attachment glycoprotein G
14	CAD	oncoprotein	20	0.416	40.853	Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
15	CCDC102B	interactor	6	0.600	3.667	Filament (PF00038, IPR001664): Intermediate filament protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 (PF01576, IPR002928): Myosin tail PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
16	CCDC8	interactor	23	0.437	53.345	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
17	CCDC88C	interactor	3	0.667	0.667	DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Fez1 (PF06818): Fez1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper HOOK (PF05622, IPR008636): HOOK protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
18	CCL2	interactor	9	0.714	1.624	IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
19	CCND1	oncoprotein	13	0.424	17.391	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
20	CCNH	oncoprotein	8	0.714	3.683	5_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
21	CCT3	interactor	24	0.297	73.191	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
22	CCT4	interactor	22	0.351	56.412	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
23	CDC45	interactor	18	0.477	29.895	CDC45 (PF02724, IPR003874): CDC45-like protein
24	CDC6	oncoprotein	17	0.375	42.535	Cdc6_C (PF09079, IPR015163, SM01074): CDC6, C terminal winged helix domain AAA_22 (PF13401, IPR003593): AAA domain ORC5_C (PF14630, IPR020796): Origin recognition complex (ORC) subunit 5 C-terminus
25	CDC7	interactor	14	0.731	4.402	Pkinase (PF00069, IPR000719): Protein kinase domain
26	CDK2	suppressor	42	0.229	346.632	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
27	CDK7	oncoprotein	9	0.643	4.405	Pkinase (PF00069, IPR000719): Protein kinase domain
28	CEP250	interactor	10	0.489	9.369	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
29	CEP290	interactor	4	0.667	1.500	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) Fez1 (PF06818): Fez1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper HemY_N (PF07219, IPR010817): HemY protein N-terminus Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Mnd1 (PF03962, IPR005647): Mnd1 family NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Rho_Binding (PF08912, IPR015008): Rho Binding Sec20 (PF03908, IPR005606): Sec20 Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Swi5 (PF07061, IPR010760): Swi5 TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LIDHydrolase (PF10230, IPR019363): Lipid-droplet associated hydrolase KxDL (PF10241, IPR019371): Uncharacterized conserved protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain FAM76 (PF16046, IPR032017): FAM76 protein TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation CEP209_CC5 (PF16574, IPR032321): Coiled-coil region of centrosome protein CE290
30	CEP57	interactor	7	0.381	7.586	Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57 Tup_N (PF08581, IPR013890): Tup N-terminal CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
31	CLUH	interactor	4	0.667	1.667	DUF727 (PF05303, IPR007967): Protein of unknown function (DUF727) eIF3_p135 (PF12807): Translation initiation factor eIF3 subunit 135 CLU (PF13236, IPR025697): Clustered mitochondria TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat CLU_N (PF15044, IPR028275): Mitochondrial function, CLU-N-term
32	CNOT8	interactor	2	1.000	0	CAF1 (PF04857, IPR006941): CAF1 family ribonuclease
33	COPS5	protein found in more fusions	21	0.416	38.874	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
34	CRY1	interactor	6	0.700	0.876	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
35	CRY2	protein found in more fusions	11	0.400	12.351	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
36	CUL3	protein found in more fusions	35	0.251	184.086	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
37	CUL5	suppressor	21	0.338	72.420	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38	CUL7	protein found in more fusions	29	0.286	85.758	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
39	DBF4	interactor	13	0.864	1.588	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-DBF (PF07535, IPR006572, SM00586): DBF zinc finger
40	DCTN2	interactor	12	0.491	13.260	Dynamitin (PF04912): Dynamitin
41	DDX5	oncoprotein	28	0.336	75.310	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
42	DSTN	interactor	3	1.000	0	Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
43	EPAS1	suppressor	5	0.833	0.286	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
44	FBXO25	suppressor	8	0.393	8.174	Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
45	FBXO6	interactor	21	0.243	46.200	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
46	FHL2	oncoprotein	8	0.571	4.595	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
47	FN1	oncoprotein	28	0.259	129.204	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
48	GINS2	interactor	4	0.667	1.667	Sld5 (PF05916, IPR021151): GINS complex protein
49	GINS3	interactor	6	0.600	3.800	Sld5 (PF05916, IPR021151): GINS complex protein
50	GINS4	interactor	7	0.476	8.233	Sld5 (PF05916, IPR021151): GINS complex protein SLD5_C (PF16922, IPR031633): DNA replication complex GINS protein SLD5 C-terminus
51	GIPC1	interactor	2	1.000	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
52	GOLGA2	interactor	11	0.327	26.444	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
53	GSTK1	interactor	4	1.000	0	DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain
54	HAUS2	interactor	3	0.667	0.250	DpnII (PF04556, IPR007637): DpnII restriction endonuclease HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
55	HDAC5	protein found in more fusions	24	0.320	62.788	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
56	HDAC6	oncoprotein	16	0.314	39.501	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
57	HIF1A	suppressor	16	0.283	53.842	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
58	HIPK4	interactor	2	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
59	HIST1H2BA	interactor	11	0.636	7.360	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
60	HIST1H3E	interactor	20	0.505	29.788	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
61	HIST1H4A	interactor	23	0.415	56.187	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
62	HIST3H3	interactor	16	0.417	30.301	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
63	HSP90AB1	oncoprotein	33	0.238	178.076	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
64	HYOU1	interactor	8	0.357	3.131	HSP70 (PF00012, IPR013126): Hsp70 protein AbiEi_3_N (PF17194): Transcriptional regulator, AbiEi antitoxin N-terminal domain
65	IKBKG	interactor	14	0.231	42.525	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
66	ILF2	interactor	27	0.407	72.020	DZF (PF07528, IPR006561, SM00572): DZF domain
67	INTS6	suppressor	5	0.800	0.439	VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
68	IPO5	interactor	10	0.333	7.505	HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat AAA_30 (PF13604): AAA domain HEAT_2 (PF13646): HEAT repeats PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
69	ITGA4	interactor	25	0.380	66.400	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
70	KCTD5	interactor	5	0.667	1.333	BTB_2 (PF02214, IPR003131): BTB/POZ domain
71	KIFC3	oncoprotein	8	0.381	10.833	Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
72	KMT5C	interactor	2	1.000	0	SET (PF00856, IPR001214, SM00317): SET domain
73	L3MBTL1	protein found in more fusions	10	0.639	4.148	MBT (PF02820, IPR004092, SM00561): mbt repeat zf-C2HC (PF01530, IPR002515, SM00343): Zinc finger, C2HC type
74	LAMP2	protein found in more fusions	6	0.400	2.622	Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
75	MAPRE2	protein found in more fusions	6	0.700	0.622	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif
76	MBIP	interactor	2	0	0	DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
77	MCM10	interactor	17	0.493	26.665	Mcm10 (PF09332, IPR015411): Mcm10 replication factor zf-primase (PF09329, IPR015408): Primase zinc finger AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
78	MCM2	oncoprotein	63	0.216	835.307	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
79	MCM3	interactor	45	0.263	359.724	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
80	MCM4	interactor	47	0.281	343.699	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
81	MCM5	oncoprotein	38	0.327	185.140	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
82	MCM6	interactor	44	0.317	248.193	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 YmgB (PF10798, IPR024753): Biofilm development protein YmgB/AriR MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
83	MCM8	interactor	6	0.733	1.039	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_OB (PF17207): MCM OB domain
84	MCMBP	interactor	11	0.673	5.429	MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
85	MIB1	protein found in more fusions	7	0.533	4.433	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat MIB_HERC2 (PF06701, IPR010606): Mib_herc2 ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
86	MIPOL1	interactor	3	1.000	0	Bac_globin (PF01152, IPR001486): Bacterial-like globin CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rho_Binding (PF08912, IPR015008): Rho Binding IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
87	MMS22L	interactor	11	0.818	2.518	Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain MMS22L_N (PF14910, IPR029425): S-phase genomic integrity recombination mediator, N-terminal MMS22L_C (PF14911, IPR029424): S-phase genomic integrity recombination mediator, C-terminal
88	MNAT1	oncoprotein	7	0.810	2.067	MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1 Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
89	MYC	oncoprotein	23	0.260	97.596	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
90	NAB2	oncoprotein	2	0	0	NCD1 (PF04904, IPR006988): NAB conserved region 1 (NCD1) NCD2 (PF04905, IPR006989): NAB conserved region 2 (NCD2)
91	NEK6	interactor	5	0.500	2.500	Pkinase (PF00069, IPR000719): Protein kinase domain
92	NELFCD	oncoprotein	3	1.000	0	TH1 (PF04858, IPR006942): TH1 protein
93	NTRK1	oncoprotein	58	0.182	800.811	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
94	NXF1	interactor	33	0.183	255.558	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
95	OBSL1	interactor	27	0.360	56.041	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
96	ORC1	interactor	16	0.583	17.274	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) BAH (PF01426, IPR001025, SM00439): BAH domain Cdc6_C (PF09079, IPR015163, SM01074): CDC6, C terminal winged helix domain
97	ORC2	protein found in more fusions	24	0.498	51.062	ORC2 (PF04084, IPR007220): Origin recognition complex subunit 2 DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
98	ORC3	interactor	15	0.543	14.657	ORC3_N (PF07034, IPR020795): Origin recognition complex (ORC) subunit 3 N-terminus
99	ORC4	interactor	18	0.503	30.568	AAA_16 (PF13191): AAA ATPase domain ORC4_C (PF14629, IPR032705): Origin recognition complex (ORC) subunit 4 C-terminus
100	ORC5	interactor	16	0.705	7.297	AAA_16 (PF13191): AAA ATPase domain ORC5_C (PF14630, IPR020796): Origin recognition complex (ORC) subunit 5 C-terminus
101	ORC6	interactor	16	0.592	13.488	ORC6 (PF05460, IPR008721): Origin recognition complex subunit 6 (ORC6)
102	PARK2	suppressor	11	0.289	11.886	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
103	PCNA	oncoprotein	28	0.197	159.702	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
104	PELO	interactor	4	0.500	0.783	eRF1_1 (PF03463, IPR005140): eRF1 domain 1 eRF1_2 (PF03464, IPR005141): eRF1 domain 2 eRF1_3 (PF03465, IPR005142): eRF1 domain 3
105	PIDD1	interactor	4	0.500	1.567	Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Peptidase_S68 (PF10461, IPR019502): Peptidase S68 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
106	PNMA1	oncoprotein	2	1.000	0	PNMA (PF14893, IPR026523): PNMA
107	POLR2A	protein found in more fusions	24	0.368	77.684	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
108	PRMT1	interactor	19	0.307	49.041	Methyltransf_25 (PF13649): Methyltransferase domain
109	PRRC1	interactor	3	1.000	0	NTPase_I-T (PF01931, IPR026533): Protein of unknown function DUF84
110	PSMD12	interactor	8	0.429	6.400	Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain
111	PSMD2	oncoprotein	25	0.250	105.850	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
112	RAD21	oncoprotein	16	0.458	15.760	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
113	RANBP6	interactor	2	1.000	0	HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats
114	RASSF10	suppressor	2	1.000	0	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) FliJ (PF02050, IPR012823): Flagellar FliJ protein Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
115	RB1	suppressor	10	0.356	17.997	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
116	RBBP4	oncoprotein	22	0.190	122.080	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
117	RBL1	suppressor	7	0.619	4.109	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
118	RBL2	suppressor	5	0.600	2.000	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pap_E4 (PF02711, IPR003861): E4 protein RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain SLH (PF00395, IPR001119): S-layer homology domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
119	RBM8A	interactor	11	0.333	16.072	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
120	RECQL5	oncoprotein	4	1.000	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5) SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding TAtT (PF16811, IPR031823): TRAP transporter T-component
121	RNF2	interactor	23	0.225	95.207	zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
122	RPA1	suppressor	32	0.327	164.235	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
123	SENP3	interactor	17	0.360	50.088	Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis) Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
124	SF3A1	interactor	19	0.474	26.949	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
125	SF3B1	oncoprotein	24	0.449	39.175	Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
126	SMC1A	oncoprotein	18	0.375	22.890	SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
127	SNRPA1	interactor	14	0.451	19.669	LRR_9 (PF14580): Leucine-rich repeat
128	SNTA1	interactor	2	1.000	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain
129	SP2	interactor	3	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
130	SSRP1	interactor	21	0.524	30.429	Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like SSrecog (PF03531, IPR024954): Structure-specific recognition protein (SSRP1) YABBY (PF04690, IPR006780): YABBY protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 Coilin_N (PF15862, IPR031722): Coilin N-terminus
131	STAU1	protein found in more fusions	17	0.517	17.189	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
132	SUZ12	suppressor	16	0.305	31.091	DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
133	TCEB1	oncoprotein	7	0.667	3.522	Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
134	TERF1	interactor	12	0.327	23.182	TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
135	TERF2	interactor	10	0.472	8.931	Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
136	TIMELESS	interactor	7	0.381	8.817	Myc_N (PF01056, IPR012682): Myc amino-terminal region TIMELESS (PF04821, IPR006906): Timeless protein TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
137	TIPIN	interactor	8	0.536	7.208	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Swi3 (PF07962, IPR012923): Replication Fork Protection Component Swi3 CEP19 (PF14933, IPR029412): CEP19-like protein
138	TOMM34	interactor	9	0.500	8.467	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SHNi-TPR (PF10516, IPR019544): SHNi-TPR TPR_12 (PF13424): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919)
139	TONSL	interactor	16	0.676	12.465	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat LRR_6 (PF13516, IPR001611): Leucine Rich repeat Ank_4 (PF13637): Ankyrin repeats (many copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat Ank_5 (PF13857): Ankyrin repeats (many copies) UPF0697 (PF15117, IPR029368): Uncharacterised protein family UPF0697
140	TRAF6	protein found in more fusions	8	0.381	6.532	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
141	TRIM16	interactor	6	0.467	5.452	SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
142	TRIM27	oncoprotein	10	0.306	20.286	IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
143	TRIM54	interactor	6	0.500	5.000	DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) zf-HIT (PF04438, IPR007529): HIT zinc finger zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
144	UBE3A	oncoprotein	9	0.536	6.714	HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
145	UBQLN1	protein found in more fusions	10	0.389	14.475	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X
146	USHBP1	interactor	3	1.000	0	DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SlyX (PF04102, IPR007236): SlyX MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome YlqD (PF11068, IPR021297): YlqD protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family
147	VCAM1	interactor	18	0.464	20.612	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
148	VHL	suppressor	17	0.400	31.234	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
149	VPS26A	protein found in more fusions	7	0.667	2.491	Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
150	VPS29	interactor	4	0.833	0.500	Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
151	VPS35	protein found in more fusions	11	0.378	12.807	FerA (PF08165, IPR012560): FerA (NUC095) domain Vps35 (PF03635, IPR005378): Vacuolar protein sorting-associated protein 35

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