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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)182
The number (and %) of the onco-proteins46 (25.27 %)
The number (and %) of the tumor suppressors23 (12.64 %)
Total number of binary PPIs (saturation %)686 (4.16 %)
The number (and %) of affected PPIs182 (26.53 %)
The number of possible different fusions26
PPI diameter2
PPI radius1
The average degree of PPI6.934
Assortativity coefficient-0.3759
The network average Clustering coefficient0.494
The number (and %) of a zero Clustering coefficients41 (22.53 %)
The number (and %) of a zero Betweenness Centrality79 (43.41 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LYN All fusions
: BU674256;
Proteins found in more fusions UGP2 (see 1 fusions); MME (see 1 fusions); SYK (see 1 fusions); MCL1 (see 2 fusions); TNF (see 1 fusions); GAB2 (see 3 fusions); HSP90AA1 (see 2 fusions); LYN (see 2 fusions); CBL (see 1 fusions); TRIM28 (see 1 fusions); JAK2 (see 3 fusions); LAMP2 (see 1 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); KHDRBS1 (see 1 fusions); PRKDC (see 3 fusions); PAG1 (see 1 fusions); SH3KBP1 (see 1 fusions); PDE4D (see 2 fusions); EGFR (see 2 fusions); NEDD9 (see 1 fusions); SHC1 (see 1 fusions); PTK2 (see 2 fusions); FGFR2 (see 3 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LYNparental protein1820.02827910.746Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
2 ABCE1interactor70.4676.505ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 ACSL3oncoprotein40.5001.582AMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
4 ADAM15interactor30.6670.400CD20 (PF04103, IPR007237): CD20-like family
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich
Disintegrin (PF00200, IPR001762, SM00050): Disintegrin
5 ADAM22interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich
Disintegrin (PF00200, IPR001762, SM00050): Disintegrin
6 ANGPT2interactor21.0000CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
SlyX (PF04102, IPR007236): SlyX
Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
7 ANKRD54interactor100Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_5 (PF13857): Ankyrin repeats (many copies)
8 ANLNoncoprotein50.7002.333Anillin (PF08174, IPR012966): Cell division protein anillin
PH (PF00169, IPR001849, SM00233): PH domain
Anillin_N (PF16018, IPR031970): Anillin N-terminus
9 ARHGAP19interactor21.0000Endonuc-dimeris (PF09124, IPR015208): T4 recombination endonuclease VII, dimerisation
His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
10 BANK1interactor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DBB (PF14545, IPR017893): Dof, BCAP, and BANK (DBB) motif
11 BCAR1oncoprotein110.41823.898Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
12 BLNKsuppressor80.6075.769SH2 (PF00017, IPR000980, SM00252): SH2 domain
13 BTKsuppressor130.34826.760BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
14 C21orf59interactor100BRX (PF08381, IPR013591): Transcription factor regulating root and shoot growth via Pin3
DUF2870 (PF11069, IPR021298): Protein of unknown function (DUF2870)
15 C2orf47interactor31.0000Tim44 (PF04280, IPR007379, SM00978): Tim44-like domain
16 CBLsuppressor270.283153.407Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
17 CBLConcoprotein40.8330.167Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
18 CBX6interactor30.6670.250Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
CBX7_C (PF17218): CBX family C-terminal motif
19 CCDC8interactor140.28228.327Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
20 CCNL2interactor21.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
21 CCP110interactor70.5246.917DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
IFT20 (PF14931, IPR028172): Intraflagellar transport complex B, subunit 20
CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
CALM_bind (PF16025): Calcium-dependent calmodulin binding
22 CD22interactor60.5334.649C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
23 CD24interactor100CD24 (PF14984, IPR028029): CD24 protein
24 CD36interactor100CD36 (PF01130, IPR002159): CD36 family
25 CD72interactor41.0000DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
26 CDH23interactor100Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
DUF3364 (PF11844, IPR024564): Domain of unknown function (DUF3364)
Cadherin_3 (PF16184): Cadherin-like
27 CDK1oncoprotein120.47315.051Pkinase (PF00069, IPR000719): Protein kinase domain
28 CDK2suppressor220.27698.036Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
29 CDK4oncoprotein50.5002.067Pkinase (PF00069, IPR000719): Protein kinase domain
30 CDKN1Bsuppressor70.3815.334CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
31 CENPVinteractor21.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
GFA (PF04828, IPR006913): Glutathione-dependent formaldehyde-activating enzyme
32 CEP97interactor40.8330.400IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
33 CNOT10interactor21.0000DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
POX (PF07526, IPR006563, SM00574): Associated with HOX
Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
34 CPT1Ainteractor21.0000Carn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
CPT_N (PF16484, IPR032476): Carnitine O-palmitoyltransferase N-terminus
35 CREBBPsuppressor130.42420.398Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
36 CSF1Roncoprotein60.6671.800ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
37 CSF2RBinteractor60.6001.748fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Tissue_fac (PF01108, IPR003961): Tissue factor
38 CSF3Roncoprotein30.6670.182EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
39 CSNK2Binteractor70.3336.039CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
40 CTLA4interactor40.6670.400V-set (PF07686, IPR013106): Immunoglobulin V-set domain
41 CYP4V2interactor100p450 (PF00067, IPR001128): Cytochrome P450
42 DDX21interactor70.4296.523CRT10 (PF08728, IPR014839): CRT10
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Sulfatase (PF00884, IPR000917): Sulfatase
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
43 DENND2Cinteractor100dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
44 DKFZP434K028interactor100NA
45 DNA2interactor21.0000Dna2 (PF08696, IPR014808): DNA replication factor Dna2
PDDEXK_1 (PF12705): PD-(D/E)XK nuclease superfamily
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
46 DOK1suppressor90.5366.467IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
47 DTLinteractor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
48 DTX3oncoprotein100zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
49 DUOXA1interactor100DuoxA (PF10204, IPR018469): Dual oxidase maturation factor
50 DVL2interactor50.8330.105DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
51 E2F6oncoprotein21.0000BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
52 EGFRoncoprotein340.233275.598Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
53 ELAVL1oncoprotein310.120334.011RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
54 EPORoncoprotein80.6792.180EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
55 ERO1Ainteractor21.0000ERO1 (PF04137, IPR007266): Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
56 EVLoncoprotein31.0000VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
57 FASLGinteractor50.5003.222PAP_PilO (PF06864, IPR009663): Pilin accessory protein (PilO)
TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
58 FBXO28interactor31.0000Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
F-box (PF00646, IPR001810, SM00256): F-box domain
FAM76 (PF16046, IPR032017): FAM76 protein
59 FCARinteractor100Adeno_E1B_19K (PF01691, IPR002924): Adenovirus E1B 19K protein / small t-antigen
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
60 FCGR2Ainteractor31.0000DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
61 FGFR1OPoncoprotein31.0000FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain
62 FGFR2oncoprotein50.8330.500Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
63 FRS2interactor50.6002.900IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
64 FSD1Linteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IncA (PF04156, IPR007285): IncA protein
RE_ApaLI (PF09499, IPR019036): ApaLI-like restriction endonuclease
SPRY (PF00622, IPR003877, SM00449): SPRY domain
65 GAB2oncoprotein80.4296.297PH (PF00169, IPR001849, SM00233): PH domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
66 GAB3interactor21.0000PH (PF00169, IPR001849, SM00233): PH domain
67 GP1BBinteractor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
68 GP6interactor21.0000Ig_2 (PF13895, IPR007110): Immunoglobulin domain
69 GTPBP3interactor200TrmE_N (PF10396, IPR018948): GTP-binding protein TrmE N-terminus
MnmE_helical (PF12631, IPR025867): MnmE helical domain
70 HBS1Linteractor21.0000HBS1_N (PF08938, IPR015033): HBS1 N-terminus
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
71 HCLS1interactor40.5002.400HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
TMEM210 (PF15195, IPR028123): TMEM210 family
SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
72 HDGFRP3interactor100PPP4R2 (PF09184, IPR015267): PPP4R2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
73 HNRNPKoncoprotein110.40015.955ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
74 HOXB5interactor40.5002.400DUF739 (PF05339, IPR008003): Protein of unknown function (DUF739)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
75 HOXC4interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
76 HSP90AA1oncoprotein310.228240.141HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
77 HSP90B1suppressor80.5005.751CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
78 HTR2Ainteractor30.6670.1827tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL
79 IKBKGinteractor150.34142.877CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
80 IL1Boncoprotein21.0000IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18
IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide
81 INPP5Dinteractor110.40020.532Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SH2 (PF00017, IPR000980, SM00252): SH2 domain
82 JAK2oncoprotein180.36055.305FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
83 KHDRBS1protein found in more fusions140.33334.073KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
84 KHDRBS2interactor50.8330.667KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
85 KIToncoprotein110.40019.537ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
86 KLC2interactor40.5002.250TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
87 KYNUinteractor100Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit
88 LAMP2protein found in more fusions50.6671.400Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
89 LCP2interactor90.52813.830SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SDA1 (PF05285, IPR007949): SDA1
SH2 (PF00017, IPR000980, SM00252): SH2 domain
90 LIMA1suppressor100.5568.008LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
91 LNP1interactor100LNP1 (PF15419, IPR029280): Leukemia NUP98 fusion partner 1
92 LRRIQ3interactor1002CSK_N (PF08521, IPR013727): Two-component sensor kinase N-terminal
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
LRR_9 (PF14580): Leucine-rich repeat
DUF4883 (PF16224, IPR032619): DOmain of unknown function (DUF4883)
93 MAATS1interactor100IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
PaaSYMP (PF14738, IPR032840): Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1
94 MAPK3oncoprotein70.4006.500Pkinase (PF00069, IPR000719): Protein kinase domain
95 MCL1oncoprotein41.0000Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
96 MMEsuppressor40.6670.500Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
97 MUC1oncoprotein50.9000.250SEA (PF01390, IPR000082, SM00200): SEA domain
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
Collectrin (PF16959, IPR031588): Renal amino acid transporter
98 MYH9suppressor130.44926.896IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
99 NDFIP2interactor40.6670.404DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370)
100 NEDD9protein found in more fusions60.7001.182Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
101 NFYBinteractor41.0000CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
102 NKAPLinteractor100SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
103 NMT1oncoprotein30.6670.105NMT (PF01233, IPR022676): Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
NMT_C (PF02799, IPR022677): Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
104 NTRK1oncoprotein390.145473.583I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
105 OCLNinteractor21.0000MARVEL (PF01284, IPR008253): Membrane-associating domain
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
106 OSBPL11interactor40.6671.067Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
107 PAG1protein found in more fusions90.39313.364PAG (PF15347, IPR032748): Phosphoprotein associated with glycosphingolipid-enriched
108 PAK1oncoprotein70.5335.000PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
109 PAN2interactor110.43616.990RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
110 PDE4Aoncoprotein100NadA (PF02445, IPR003473): Quinolinate synthetase A protein
PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
111 PDE4Doncoprotein40.6670.250Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
112 PECAM1oncoprotein50.5000.718C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
113 PIK3CGoncoprotein30.6670.333Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3244 (PF11589, IPR021638): Domain of unknown function (DUF3244)
DUF4135 (PF13575, IPR025410): Domain of unknown function (DUF4135)
114 PIK3R3interactor110.45521.360SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
115 PLAURoncoprotein40.5002.667Toxin_1 (PF00087, IPR003571): Snake toxin
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
116 PLCG2interactor80.5007.320C2 (PF00168, IPR000008, SM00239): C2 domain
EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
117 PLEKHH2interactor100Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
FERM_M (PF00373, IPR019748): FERM central domain
MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain
PH (PF00169, IPR001849, SM00233): PH domain
118 PPP1R15Ainteractor21.0000FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
PP1c_bdg (PF10488, IPR019523): Phosphatase-1 catalytic subunit binding region
SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
119 PPP1R8interactor21.0000FHA (PF00498, IPR000253, SM00240): FHA domain
120 PRAM1interactor50.5004.000hSH3 (PF14603, IPR029294): Helically-extended SH3 domain
121 PRKCBsuppressor80.5715.419C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
122 PRKDCprotein found in more fusions110.6005.844FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
123 PRUNE2interactor100DHHA2 (PF02833, IPR004097, SM01131): DHHA2 domain
BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
124 PTK2protein found in more fusions190.44439.756FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
125 PTK2Binteractor150.39638.755FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
126 PTPN6suppressor180.30165.668SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
127 PTPRCsuppressor40.5003.000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PTP_N (PF12453, IPR024739): Protein tyrosine phosphatase N terminal
CD45 (PF12567, IPR016335): Leukocyte receptor CD45
SCIMP (PF15050, IPR028181): SCIMP protein
128 RASSF8suppressor100ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
FliD_C (PF07195, IPR010809): Flagellar hook-associated protein 2 C-terminus
PEARLI-4 (PF05278, IPR007942): Arabidopsis phospholipase-like protein (PEARLI 4)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
129 RBM11interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
130 RDXinteractor31.0000ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
131 RGS16interactor31.0000RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
132 RIMS2interactor100C2 (PF00168, IPR000008, SM00239): C2 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
133 RNF180suppressor100Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
134 RPL10suppressor70.42910.150Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
135 RPS6KB1interactor80.4765.010Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
136 RPS6KB2interactor80.4647.978Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
137 SCG3interactor100SGIII (PF15467, IPR026197): Secretogranin-3
138 SCIMPinteractor100SCIMP (PF15050, IPR028181): SCIMP protein
139 SH2D1Ainteractor60.6002.872SH2 (PF00017, IPR000980, SM00252): SH2 domain
140 SH2D3Cinteractor40.6670.750RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
141 SH2D4Ainteractor30.6671.000Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
142 SH3KBP1protein found in more fusions160.35245.605Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
143 SHC1oncoprotein240.233136.529PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
144 SKAP1interactor90.35716.667PH (PF00169, IPR001849, SM00233): PH domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
145 SKAP2interactor70.5247.000PH (PF00169, IPR001849, SM00233): PH domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_9 (PF15410): Pleckstrin homology domain
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
146 SLC12A4interactor21.0000AA_permease (PF00324, IPR004841): Amino acid permease
SLC12 (PF03522, IPR018491): Solute carrier family 12
147 SLC22A16interactor100Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
148 SLC25A41interactor40.5001.800Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
149 SLITRK4interactor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
150 SPESP1interactor21.0000SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
151 SRConcoprotein470.131737.644Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
152 STAT3suppressor160.48627.287SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
153 SVILinteractor80.6434.175Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
154 SYKsuppressor240.257133.298Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
155 TADA2Ainteractor40.8330.286SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
156 TECinteractor70.5245.633BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
157 TFDP3interactor21.0000DP (PF08781, IPR014889, SM01138): Transcription factor DP
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
158 TGDSinteractor100GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase
159 TMEM17interactor80.25018.667Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
160 TMEM185Ainteractor30.6670.400Tmemb_185A (PF10269, IPR019396): Transmembrane Fragile-X-F protein
161 TMX1interactor30.6670.667OST3_OST6 (PF04756, IPR021149): OST3 / OST6 family, transporter family
Thioredoxin (PF00085, IPR013766): Thioredoxin
FAM176 (PF14851): FAM176 family
162 TNFoncoprotein50.6671.667TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
163 TNFSF12suppressor100TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
164 TNK2interactor90.6433.922CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GTPase_binding (PF09027, IPR015116): GTPase binding
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
UBA_4 (PF14555): UBA-like domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
165 TP53suppressor330.179305.025DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
166 TPTE2suppressor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Ion_trans (PF00520, IPR005821): Ion transport protein
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
167 TRAT1interactor21.0000SIT (PF15330): SHP2-interacting transmembrane adaptor protein, SIT
168 TRIM28protein found in more fusions100.4449.876ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
169 TRPV4interactor21.0000Ion_trans (PF00520, IPR005821): Ion transport protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
170 TSNAXinteractor100Translin (PF01997, IPR002848): Translin family
171 TTYH3interactor30.6670.500Tweety (PF04906, IPR006990): Tweety
172 TUBB4Ainteractor21.0000Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
173 TYK2interactor90.32114.186Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
174 TYW1interactor21.0000Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
Radical_SAM (PF04055, IPR007197): Radical SAM superfamily
Wyosine_form (PF08608, IPR013917): Wyosine base formation
175 UGP2protein found in more fusions41.0000UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
176 UHRF2suppressor90.39314.200PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
177 UNC119interactor100GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
178 YEATS4interactor100YEATS (PF03366, IPR005033): YEATS family
SOGA (PF11365, IPR027881): Protein SOGA
179 ZCCHC7interactor21.0000zf-CCHC (PF00098, IPR001878): Zinc knuckle
DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318)
zf-CCHC_3 (PF13917): Zinc knuckle
180 ZNF189interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Fer4_9 (PF13187, IPR017896): 4Fe-4S dicluster domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
181 ZNF423oncoprotein100zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zinc_ribbon_9 (PF14369): zinc-ribbon
Zf_RING (PF16744, IPR031946): KIAA1045 RING finger
182 ZNF577interactor100Hydrophobin_2 (PF06766, IPR010636): Fungal hydrophobin
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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