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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)109
The number (and %) of the onco-proteins22 (20.18 %)
The number (and %) of the tumor suppressors7 (6.42 %)
Total number of binary PPIs (saturation %)657 (11.16 %)
The number (and %) of affected PPIs109 (16.59 %)
The number of possible different fusions17
PPI diameter2
PPI radius1
The average degree of PPI11.560
Assortativity coefficient-0.2911
The network average Clustering coefficient0.540
The number (and %) of a zero Clustering coefficients12 (11.01 %)
The number (and %) of a zero Betweenness Centrality28 (25.69 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions UBE2O (see 1 fusions); LUC7L2 (see 2 fusions); PRMT5 (see 2 fusions); U2AF2 (see 2 fusions); SETD2 (see 2 fusions); SRPK2 (see 1 fusions); LUC7L (see 1 fusions); PSME3 (see 2 fusions); PRDX1 (see 1 fusions); ZNF638/CDC5L (see 1 fusions); FTL (see 3 fusions); CSNK2A1 (see 1 fusions); PRPF40A (see 2 fusions); CTNNBL1 (see 1 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LUC7Lparental protein1090.0907041.553LUC7 (PF03194, IPR004882): LUC7 N_terminus
Hid1 (PF12722): High-temperature-induced dauer-formation protein
2 ACIN1interactor170.60312.978Calc_CGRP_IAPP (PF00214, IPR021116): Calcitonin / CGRP / IAPP family
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
FAM27 (PF15832, IPR031672): FAM27 D and E protein family
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
RSB_motif (PF16294, IPR032552): RNSP1-SAP18 binding (RSB) motif
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
3 BARD1suppressor240.36080.207BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
4 BCLAF1oncoprotein160.50821.601API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
5 C1QBPinteractor120.43926.594MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
6 CALM1interactor50.6001.522EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
7 CASC3oncoprotein40.6670.476Btz (PF09405, IPR018545, SM01044): CASC3/Barentsz eIF4AIII binding
UPF0560 (PF10577, IPR018890): Uncharacterised protein family UPF0560
PRIMA1 (PF16101): Proline-rich membrane anchor 1
8 CCDC8interactor90.35713.200Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
9 CDC5Lprotein found in more fusions250.38078.647OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
10 CHCHD2P9interactor100NA
11 CHERPinteractor130.52616.813CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
G-patch (PF01585, IPR000467, SM00443): G-patch domain
HpaP (PF09483, IPR013390): Type III secretion protein (HpaP)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
Surp (PF01805, IPR000061, SM00648): Surp module
12 CLASRPinteractor50.7000.726Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Pap_E4 (PF02711, IPR003861): E4 protein
RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1)
S-antigen (PF05756, IPR008825): S-antigen protein
Transformer (PF06495, IPR010519): Fruit fly transformer protein
DRY_EERY (PF09750, IPR019147, SM01141): Alternative splicing regulator
LRRFIP (PF09738, IPR019139): LRRFIP family
DUF4554 (PF15091, IPR028040): Domain of unknown function (DUF4554)
13 CLK2interactor200.35759.599DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-met (PF12874): Zinc-finger of C2H2 type
14 CLK3interactor160.37136.629Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
15 CMASinteractor100CTP_transf_3 (PF02348, IPR003329): Cytidylyltransferase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
16 CPSF7interactor90.5282.974CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
17 CSNK2A1oncoprotein240.37268.437Pkinase (PF00069, IPR000719): Protein kinase domain
18 CSNK2A2interactor160.50029.168Pkinase (PF00069, IPR000719): Protein kinase domain
19 CTNNBL1protein found in more fusions60.5001.305Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4
CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
20 DDX50interactor50.7002.500CDC45 (PF02724, IPR003874): CDC45-like protein
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 EAF1suppressor60.4004.960Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Peroxin-3 (PF04882, IPR006966): Peroxin-3
EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor
22 EIF2B1interactor50.8330.333IF-2B (PF01008, IPR000649): Initiation factor 2 subunit family
23 FAM173Ainteractor21.0000Methyltransf_23 (PF13489): Methyltransferase domain
24 FBXO25suppressor30.6670.500Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
25 FTLprotein found in more fusions31.0000Ferritin (PF00210, IPR008331): Ferritin-like domain
26 FXR1interactor80.6673.011Agenet (PF05641, IPR008395, SM00743): Agenet domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
FXR_C3 (PF16097, IPR032177): Fragile X-related 1 protein C-terminal region 3
27 GADD45Gsuppressor21.0000Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
28 GPATCH8interactor50.6001.650G-patch (PF01585, IPR000467, SM00443): G-patch domain
Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
Use1 (PF09753, IPR019150): Membrane fusion protein Use1
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SOBP (PF15279, IPR026092): Sine oculis-binding protein
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
29 HNRNPRinteractor160.50029.614RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
30 IBA57interactor100GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain
GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain
31 JMJD6interactor50.6001.303AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
32 KBTBD6interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
33 LARP1interactor100.6443.260La (PF05383, IPR006630, SM00715): La domain
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
34 LBRinteractor50.7001.182ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family
LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain
35 LSM14Binteractor31.0000FDF (PF09532, IPR019050, SM01199): FDF domain
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
36 LUC7L2protein found in more fusions500.222568.766LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
37 LUC7L3interactor160.41931.461LUC7 (PF03194, IPR004882): LUC7 N_terminus
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
38 MEPCEinteractor120.50010.430Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
39 MKRN1interactor31.0000Opy2 (PF09463, IPR018571): Opy2 protein
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
CD52 (PF15116, IPR026643): CAMPATH-1 antigen
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
40 MRM3interactor100SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
SpoU_sub_bind (PF08032, IPR013123, SM00967): RNA 2'-O ribose methyltransferase substrate binding
41 MRPL46interactor21.0000NUDIX (PF00293, IPR000086): NUDIX domain
MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46
42 MRPS22interactor100.62211.156MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22
43 MRPS27interactor60.9330.222MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27
44 MRPS5interactor80.8930.889Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
45 MRPS9interactor80.7862.678Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
46 MRS2interactor100CcmB (PF03379, IPR003544): CcmB protein
rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
47 NANOGinteractor90.35710.867Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
48 NFKBIL1interactor50.4003.852Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
49 NKAPinteractor80.6192.188SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
NKAP (PF15692): NF-kappa-B-activating protein
50 NKTRinteractor21.0000Conotoxin (PF02950, IPR004214): Conotoxin
Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Transformer (PF06495, IPR010519): Fruit fly transformer protein
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
YqfQ (PF14181, IPR025571): YqfQ-like protein
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
Spem1 (PF15670, IPR031368): Spermatid maturation protein 1
Coilin_N (PF15862, IPR031722): Coilin N-terminus
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
51 NLRP3oncoprotein21.0000NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
52 NRDCinteractor31.0000Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
53 NTRK1oncoprotein540.199727.377I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
54 PHF10interactor100Herpes_MCP (PF03122, IPR000912): Herpes virus major capsid protein
PHD (PF00628, IPR019787, SM00249): PHD-finger
MRI (PF15325, IPR028278): Modulator of retrovirus infection
55 PNNsuppressor210.52438.906Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
56 PPIGinteractor60.7331.019Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
57 PRDX1oncoprotein60.7001.178AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
58 PRMT5protein found in more fusions100.33314.016PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
59 PRPF38Binteractor30.6670.500PRP38 (PF03371, IPR005037): PRP38 family
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
60 PRPF40Aprotein found in more fusions250.42068.172FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
61 PRPF4Boncoprotein120.5618.897Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
Ureide_permease (PF07168, IPR009834): Ureide permease
Pkinase (PF00069, IPR000719): Protein kinase domain
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
62 PRRC2Ainteractor40.8330.500BAT2_N (PF07001, IPR009738): BAT2 N-terminus
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
63 PSME3protein found in more fusions100.38911.319PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
64 PTCD3interactor120.56115.125PPR (PF01535, IPR002885): PPR repeat
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
65 RBBP6oncoprotein51.0000DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936)
DWNN (PF08783, IPR014891): DWNN domain
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
U-box (PF04564, IPR003613, SM00504): U-box domain
SBF2 (PF12335, IPR022096): Myotubularin protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
PRIMA1 (PF16101): Proline-rich membrane anchor 1
66 RBM23interactor80.4647.297RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
RSRP (PF17069): Arginine/Serine-Rich protein 1
67 RBM25interactor110.6008.184Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
68 RBM26interactor31.0000Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TT_ORF1 (PF02956, IPR004219): TT viral orf 1
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
69 RBM27interactor100DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
70 RBM7interactor80.4645.610RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
71 RECQL4oncoprotein100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Drc1-Sld2 (PF11719, IPR021110): DNA replication and checkpoint protein
72 RNASEH1interactor100Cauli_VI (PF01693, IPR011320): Caulimovirus viroplasmin
RNase_H (PF00075, IPR002156): RNase H
73 RNPS1interactor290.37796.957RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
Macoilin (PF09726, IPR019130): Transmembrane protein
74 SCAF4interactor21.0000CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
75 SETD2suppressor40.6670.286DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
SET (PF00856, IPR001214, SM00317): SET domain
SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
WW (PF00397, IPR001202, SM00456): WW domain
DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592)
76 SF3B3interactor230.47455.544CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
77 SNRNP70interactor250.40763.598RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
78 SNRPD1interactor140.59311.664API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
79 SNRPD2interactor140.6268.633LSM (PF01423, IPR001163): LSM domain
80 SNRPD3interactor140.62610.026LSM (PF01423, IPR001163): LSM domain
81 SNW1protein found in more fusions250.44959.159SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
82 SRPK1interactor230.39574.052FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
83 SRPK2oncoprotein370.276272.424DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
84 SRPK3interactor90.4724.346Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Pkinase (PF00069, IPR000719): Protein kinase domain
85 SRRM1interactor250.43067.839DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
86 SRRM2interactor290.39497.633cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
87 SRRTinteractor110.5648.944ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546)
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
88 SRSF10interactor90.6942.546RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
89 SRSF11interactor140.61510.590Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
90 SRSF8interactor60.8000.502RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SPX (PF03105, IPR004331): SPX domain
91 SUZ12suppressor250.32685.149DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
92 SYNCRIPinteractor140.57116.938RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
93 TADA2Ainteractor90.6114.668SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
94 TCERG1interactor80.7141.871FF (PF01846, IPR002713, SM00441): FF domain
WW (PF00397, IPR001202, SM00456): WW domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
FAM150 (PF15129, IPR029364): FAM150 family
95 THRAP3oncoprotein200.51625.758API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
96 TNPO3interactor40.6670.336HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
97 TRA2Ainteractor320.292203.062DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
98 U2AF2protein found in more fusions310.43794.606RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
99 UBE2Oprotein found in more fusions41.0000BUD22 (PF09073, IPR015158): BUD22
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
100 USP50interactor100UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
101 VANGL1interactor40.6672.000Strabismus (PF06638, IPR009539): Strabismus protein
102 VANGL2interactor21.0000Strabismus (PF06638, IPR009539): Strabismus protein
103 XPO1interactor210.224112.723CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
104 YY1AP1interactor100CtnDOT_TraJ (PF07863, IPR012424): Homologues of TraJ from Bacteroides conjugative transposon
JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain
105 ZC3H18interactor140.60410.285FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Miga (PF10265, IPR019392): Mitoguardin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
106 ZCCHC8interactor70.5243.343Herpes_BLRF2 (PF05812, IPR008642): Herpesvirus BLRF2 protein
PSP (PF04046, IPR006568, SM00581): PSP
zf-CCHC (PF00098, IPR001878): Zinc knuckle
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
107 ZFP91interactor21.0000OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
108 ZNF638protein found in more fusions41.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
109 ZRANB2interactor110.50915.168RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others

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