1 |
LMNA | parental protein | 222 | 0.062 | 31301.838 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
2 |
ABCE1 | interactor | 21 | 0.321 | 42.756 | ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain |
3 |
ACE | interactor | 1 | 0 | 0 | Peptidase_M2 (PF01401, IPR001548): Angiotensin-converting enzyme |
4 |
AHCTF1 | interactor | 7 | 0.524 | 2.725 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) ELYS (PF13934, IPR025151): Nuclear pore complex assembly ELYS-bb (PF16687, IPR032040): beta-propeller of ELYS nucleoporin |
5 |
ALDH3A2 | interactor | 2 | 1.000 | 0 | Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family |
6 |
ALOX12 | oncoprotein | 2 | 0 | 0 | Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain |
7 |
ANKRA2 | interactor | 6 | 0.933 | 0.250 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
8 |
ANLN | oncoprotein | 7 | 0.429 | 6.321 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
9 |
ARPIN | interactor | 1 | 0 | 0 | UPF0552 (PF10574, IPR018889): Uncharacterised protein family UPF0552 |
10 |
BANF1 | interactor | 10 | 0.333 | 5.195 | BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor |
11 |
BAZ1B | interactor | 9 | 0.583 | 1.854 | D5_N (PF08706, IPR014818, SM00885): D5 N terminal like DDT (PF02791, IPR004022, SM00571): DDT domain DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PHD (PF00628, IPR019787, SM00249): PHD-finger YL1 (PF05764, IPR008895): YL1 nuclear protein DDRGK (PF09756, IPR019153, SM01128): DDRGK domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635) Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 FAM176 (PF14851): FAM176 family WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif |
12 |
BRIP1 | oncoprotein | 3 | 0.667 | 0.667 | DEAD_2 (PF06733, IPR010614): DEAD_2 HBB (PF06777, IPR010643): Helical and beta-bridge domain Helicase_C_2 (PF13307, IPR006555): Helicase C-terminal domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal |
13 |
C17orf49 | interactor | 5 | 0.600 | 0.987 | Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
14 |
C9orf78 | interactor | 1 | 0 | 0 | DHOR (PF06537, IPR010538): Di-haem oxidoreductase, putative peroxidase Hep_59 (PF07052, IPR010756): Hepatocellular carcinoma-associated antigen 59 PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
15 |
CC2D2A | interactor | 2 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain ZnuA (PF01297, IPR006127): Zinc-uptake complex component A periplasmic DUF4240 (PF14024, IPR025334): Protein of unknown function (DUF4240) SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 CC2D2AN-C2 (PF15625, IPR028928): CC2D2A N-terminal C2 domain |
16 |
CCDC47 | interactor | 4 | 0.500 | 1.125 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2 |
17 |
CCDC8 | interactor | 53 | 0.204 | 436.732 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
18 |
CD2AP | protein found in more fusions | 10 | 0.333 | 14.853 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil |
19 |
CDC5L | interactor | 51 | 0.257 | 371.721 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
20 |
CDH1 | suppressor | 4 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
21 |
CDK16 | oncoprotein | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CDK2 | suppressor | 41 | 0.296 | 193.848 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
23 |
CDKAL1 | interactor | 1 | 0 | 0 | Radical_SAM (PF04055, IPR007197): Radical SAM superfamily TRAM (PF01938, IPR002792): TRAM domain UPF0004 (PF00919, IPR013848): Uncharacterized protein family UPF0004 |
24 |
CHD8 | oncoprotein | 11 | 0.382 | 18.637 | BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like |
25 |
CISD2 | interactor | 1 | 0 | 0 | zf-CDGSH (PF09360, IPR018967, SM00704): Iron-binding zinc finger CDGSH type MitoNEET_N (PF10660, IPR019610): Iron-containing outer mitochondrial membrane protein N-terminus |
26 |
CLK1 | interactor | 15 | 0.286 | 29.436 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
27 |
CPSF6 | interactor | 16 | 0.450 | 25.375 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
28 |
CRK | oncoprotein | 7 | 0.524 | 4.132 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
29 |
CRKL | oncoprotein | 7 | 0.429 | 1.874 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
30 |
CTCF | suppressor | 8 | 0.357 | 7.188 | cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
31 |
CTNNB1 | oncoprotein | 31 | 0.282 | 151.123 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
32 |
CTTN | oncoprotein | 10 | 0.583 | 5.707 | FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
33 |
CUL7 | protein found in more fusions | 73 | 0.180 | 737.757 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
34 |
CXorf56 | interactor | 2 | 1.000 | 0 | DUF4410 (PF14366, IPR025522): Domain of unknown function (DUF4410) |
35 |
DDX3X | suppressor | 25 | 0.390 | 45.986 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
DDX42 | interactor | 15 | 0.495 | 12.058 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
37 |
DDX46 | interactor | 11 | 0.527 | 4.698 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) CdAMP_rec (PF06153, IPR010375): Cyclic-di-AMP receptor DDRGK (PF09756, IPR019153, SM01128): DDRGK domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAM176 (PF14851): FAM176 family |
38 |
DGCR14 | interactor | 5 | 0.600 | 2.833 | Es2 (PF09751, IPR019148): Nuclear protein Es2 |
39 |
DNAJC1 | interactor | 1 | 0 | 0 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4234 (PF14018, IPR025328): Domain of unknown function (DUF4234) |
40 |
DUSP13 | interactor | 1 | 0 | 0 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PMAIP1 (PF15150, IPR024140): Phorbol-12-myristate-13-acetate-induced |
41 |
DYNLT1 | interactor | 8 | 0.286 | 16.733 | Tctex-1 (PF03645, IPR005334): Tctex-1 family |
42 |
EED | suppressor | 52 | 0.165 | 408.266 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
43 |
EEF1D | protein found in more fusions | 21 | 0.311 | 59.911 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
44 |
EGF | oncoprotein | 7 | 0.667 | 3.400 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050) |
45 |
EIF5 | interactor | 4 | 0.833 | 0.051 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon |
46 |
EMD | interactor | 27 | 0.329 | 112.281 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
47 |
ENO1 | oncoprotein | 28 | 0.384 | 67.574 | Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain |
48 |
FAM169A | interactor | 1 | 0 | 0 | DUF2464 (PF10240, IPR018798): Protein of unknown function (DUF2464) |
49 |
FAM192A | interactor | 3 | 0.667 | 0.087 | VIT1 (PF01988, IPR008217): VIT family Nefa_Nip30_N (PF10187, IPR019331): N-terminal domain of NEFA-interacting nuclear protein NIP30 |
50 |
FASN | interactor | 20 | 0.421 | 15.930 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
51 |
FBXO6 | interactor | 35 | 0.185 | 173.080 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
52 |
FHL1 | suppressor | 3 | 0.667 | 0.500 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
53 |
FLNA | suppressor | 30 | 0.287 | 124.623 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
54 |
FN1 | oncoprotein | 48 | 0.203 | 339.883 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
55 |
FUS | suppressor | 34 | 0.367 | 111.896 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
56 |
FYCO1 | interactor | 5 | 0.700 | 0.854 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
57 |
GMPPB | interactor | 1 | 0 | 0 | Hexapep (PF00132, IPR001451): Bacterial transferase hexapeptide (six repeats) NTP_transferase (PF00483, IPR005835): Nucleotidyl transferase |
58 |
GNL2 | interactor | 5 | 0.600 | 0.184 | DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase NGP1NT (PF08153, IPR012971): NGP1NT (NUC091) domain SDA1 (PF05285, IPR007949): SDA1 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
59 |
GPATCH1 | interactor | 2 | 1.000 | 0 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1604 (PF07713, IPR011666): Protein of unknown function (DUF1604) FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) G-patch (PF01585, IPR000467, SM00443): G-patch domain DUF4598 (PF15370, IPR027921): Domain of unknown function (DUF4598) PIEZO (PF15917, IPR031805): Piezo FAM76 (PF16046, IPR032017): FAM76 protein |
60 |
GPKOW | interactor | 3 | 0.667 | 0.250 | KOW (PF00467, IPR005824, SM00739): KOW motif G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site |
61 |
GTF2A1 | oncoprotein | 3 | 0.667 | 0.286 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
62 |
GTF2F2 | interactor | 3 | 1.000 | 0 | TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit |
63 |
GZMA | interactor | 3 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
64 |
GZMB | interactor | 4 | 0.667 | 0.900 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
65 |
H2AFX | suppressor | 24 | 0.322 | 65.378 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
66 |
H2AFY | interactor | 8 | 0.500 | 2.475 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Macro (PF01661, IPR002589, SM00506): Macro domain Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
67 |
HCFC1 | protein found in more fusions | 11 | 0.489 | 8.676 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
68 |
HERC2 | interactor | 13 | 0.470 | 14.303 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIB_HERC2 (PF06701, IPR010606): Mib_herc2 RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
69 |
HIST1H3E | interactor | 18 | 0.307 | 36.750 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
70 |
HIST1H4G | interactor | 1 | 0 | 0 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
71 |
HN1L | interactor | 2 | 1.000 | 0 | JUPITER (PF17054): Microtubule-Associated protein Jupiter |
72 |
HNRNPA0 | interactor | 17 | 0.478 | 13.504 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
73 |
HNRNPA1 | interactor | 46 | 0.394 | 184.442 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
74 |
HNRNPA2B1 | oncoprotein | 26 | 0.397 | 39.548 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
75 |
HNRNPM | interactor | 42 | 0.280 | 255.926 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
76 |
HNRNPR | interactor | 32 | 0.355 | 130.037 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
77 |
HP1BP3 | interactor | 12 | 0.485 | 5.741 | RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SDA1 (PF05285, IPR007949): SDA1 YL1 (PF05764, IPR008895): YL1 nuclear protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family |
78 |
ILK | suppressor | 22 | 0.300 | 65.177 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
79 |
ING1 | suppressor | 6 | 0.467 | 4.142 | PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
80 |
IRAK1 | interactor | 7 | 0.467 | 3.598 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
81 |
ISG15 | suppressor | 13 | 0.231 | 20.650 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
82 |
ITGA4 | interactor | 42 | 0.257 | 187.631 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
83 |
KAT5 | suppressor | 20 | 0.327 | 75.644 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
84 |
KCTD12 | interactor | 3 | 1.000 | 0 | BTB_2 (PF02214, IPR003131): BTB/POZ domain |
85 |
KIAA0196 | interactor | 6 | 0.600 | 3.800 | Strumpellin (PF10266, IPR019393): Hereditary spastic paraplegia protein strumpellin |
86 |
KPNA6 | interactor | 8 | 0.393 | 9.553 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
87 |
KRTAP10-3 | interactor | 5 | 0.667 | 1.667 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
88 |
KRTAP10-7 | interactor | 8 | 0.333 | 12.167 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein PMG (PF05287, IPR007951): PMG protein DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
89 |
LBR | interactor | 8 | 0.500 | 2.567 | ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain |
90 |
LEMD3 | interactor | 3 | 1.000 | 0 | LEM (PF03020, IPR003887, SM00540): LEM domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
91 |
LIMK2 | interactor | 3 | 0.667 | 0.250 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain PP1_inhibitor (PF05361, IPR008025): PKC-activated protein phosphatase-1 inhibitor |
92 |
LMNB1 | interactor | 29 | 0.330 | 117.672 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain |
93 |
LMNB2 | interactor | 16 | 0.342 | 39.305 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain |
94 |
LRRC59 | interactor | 11 | 0.473 | 4.218 | Hid1 (PF12722): High-temperature-induced dauer-formation protein LRR_8 (PF13855, IPR001611): Leucine rich repeat DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366) |
95 |
MAST3 | interactor | 8 | 0.393 | 2.852 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus |
96 |
MASTL | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
97 |
MCM2 | oncoprotein | 47 | 0.310 | 252.442 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
98 |
MCM3AP | interactor | 2 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP |
99 |
MCM5 | oncoprotein | 26 | 0.406 | 64.907 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
100 |
MDC1 | suppressor | 25 | 0.370 | 64.317 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
101 |
MKI67 | interactor | 8 | 0.607 | 1.720 | FHA (PF00498, IPR000253, SM00240): FHA domain K167R (PF08065, IPR012568): K167R (NUC007) repeat PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding AROS (PF15684, IPR023262): Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 |
102 |
MLIP | interactor | 1 | 0 | 0 | MLIP (PF15274, IPR029331): Muscular LMNA-interacting protein |
103 |
MME | suppressor | 6 | 0.400 | 4.250 | Peptidase_M13 (PF01431, IPR018497): Peptidase family M13 Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13 |
104 |
MORF4L1 | interactor | 11 | 0.556 | 7.712 | MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
105 |
MORF4L2 | interactor | 10 | 0.533 | 8.070 | MRG (PF05712, IPR026541): MRG |
106 |
MOV10 | interactor | 29 | 0.197 | 166.525 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
107 |
MRE11A | oncoprotein | 21 | 0.547 | 17.847 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain |
108 |
MRGBP | interactor | 10 | 0.378 | 21.169 | Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7 |
109 |
MRPS26 | interactor | 4 | 0.500 | 0.633 | MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 |
110 |
MTDH | interactor | 4 | 0.500 | 1.050 | NST1 (PF13945, IPR025279): Salt tolerance down-regulator NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family |
111 |
MYC | oncoprotein | 34 | 0.261 | 177.724 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
112 |
NARF | interactor | 2 | 1.000 | 0 | Fe_hyd_lg_C (PF02906, IPR004108): Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU (PF02256, IPR003149, SM00902): Iron hydrogenase small subunit |
113 |
NCL | protein found in more fusions | 30 | 0.342 | 104.417 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
114 |
NELFE | interactor | 3 | 1.000 | 0 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15 |
115 |
NONO | oncoprotein | 28 | 0.373 | 56.501 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
116 |
NPLOC4 | interactor | 10 | 0.489 | 6.856 | NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4 |
117 |
NTRK1 | oncoprotein | 99 | 0.109 | 2525.410 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
118 |
NUMA1 | oncoprotein | 22 | 0.342 | 47.215 | Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
119 |
NUP133 | oncoprotein | 17 | 0.375 | 37.763 | Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal |
120 |
NUP153 | protein found in more fusions | 23 | 0.342 | 75.848 | Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region |
121 |
NUP155 | interactor | 12 | 0.424 | 5.022 | Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like |
122 |
NUP214 | oncoprotein | 13 | 0.485 | 5.606 | dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 |
123 |
NUP50 | interactor | 10 | 0.378 | 18.140 | NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain |
124 |
NUP98 | suppressor | 14 | 0.484 | 11.061 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
125 |
NXF1 | interactor | 42 | 0.187 | 338.060 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
126 |
OBSL1 | interactor | 79 | 0.168 | 949.540 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
127 |
ORC2 | protein found in more fusions | 9 | 0.714 | 1.114 | ORC2 (PF04084, IPR007220): Origin recognition complex subunit 2 DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
128 |
PAPOLA | interactor | 5 | 0.800 | 0.515 | PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein |
129 |
PARK2 | suppressor | 18 | 0.287 | 27.757 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
130 |
PARP1 | suppressor | 31 | 0.308 | 111.929 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
131 |
PCBP1 | oncoprotein | 21 | 0.367 | 35.636 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
132 |
PCGF2 | suppressor | 11 | 0.444 | 10.205 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
133 |
PCMT1 | interactor | 13 | 0.436 | 14.195 | PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) |
134 |
PCNP | interactor | 4 | 0.500 | 0.887 | PCNP (PF15473, IPR029169): PEST, proteolytic signal-containing nuclear protein family |
135 |
PDAP1 | interactor | 2 | 1.000 | 0 | PP28 (PF10252, IPR019380): Casein kinase substrate phosphoprotein PP28 |
136 |
PDCD5 | suppressor | 4 | 0.667 | 0.587 | dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
137 |
PDLIM3 | interactor | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
138 |
PGRMC2 | suppressor | 3 | 0.667 | 0.050 | Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain |
139 |
PHB | suppressor | 19 | 0.474 | 17.941 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
140 |
PML | suppressor | 15 | 0.505 | 17.071 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
141 |
PMS2 | oncoprotein | 4 | 0.667 | 1.667 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
142 |
POM121 | interactor | 4 | 1.000 | 0 | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region POM121 (PF15229): POM121 family |
143 |
PPM1G | interactor | 7 | 0.619 | 2.087 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PP2C (PF00481, IPR001932): Protein phosphatase 2C DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
144 |
PPME1 | protein found in more fusions | 9 | 0.536 | 3.653 | Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
145 |
PPP1CC | oncoprotein | 20 | 0.289 | 61.559 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
146 |
PRKCA | interactor | 9 | 0.571 | 2.412 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
147 |
PRKDC | protein found in more fusions | 40 | 0.341 | 165.981 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
148 |
PSMD10 | interactor | 7 | 0.381 | 8.733 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
149 |
RANBP2 | oncoprotein | 29 | 0.376 | 77.959 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
150 |
RANGAP1 | protein found in more fusions | 17 | 0.475 | 21.319 | RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain SDA1 (PF05285, IPR007949): SDA1 LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
151 |
RAPGEF2 | interactor | 2 | 1.000 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain |
152 |
RB1 | suppressor | 17 | 0.426 | 34.757 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
153 |
RBBP4 | oncoprotein | 24 | 0.308 | 77.500 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
154 |
RBM10 | interactor | 16 | 0.305 | 35.577 | G-patch (PF01585, IPR000467, SM00443): G-patch domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site zf-C2H2_4 (PF13894): C2H2-type zinc finger DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337) FAM176 (PF14851): FAM176 family |
155 |
RFXANK | interactor | 8 | 0.429 | 3.362 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
156 |
RIF1 | interactor | 12 | 0.409 | 14.343 | Rif1_N (PF12231, IPR022031): Rap1-interacting factor 1 N terminal DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519) NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family |
157 |
RNF113A | interactor | 1 | 0 | 0 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8 zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
158 |
ROCK2 | interactor | 6 | 0.733 | 2.333 | Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator ZapB (PF06005, IPR009252): Cell division protein ZapB PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain Rho_Binding (PF08912, IPR015008): Rho Binding C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
159 |
RPA1 | suppressor | 51 | 0.262 | 395.641 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
160 |
RUVBL1 | oncoprotein | 31 | 0.269 | 160.420 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
161 |
SAP30BP | interactor | 7 | 0.571 | 2.493 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HCNGP (PF07818, IPR012479): HCNGP-like protein Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
162 |
SCARNA22 | interactor | 22 | 0.281 | 41.592 | NA |
163 |
SCML2 | interactor | 2 | 1.000 | 0 | MBT (PF02820, IPR004092, SM00561): mbt repeat SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SLED (PF12140, IPR021987): SLED domain Ashwin (PF15323, IPR024887): Developmental protein RBR (PF17208): RNA binding Region |
164 |
SDCBP | interactor | 5 | 0.600 | 3.333 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
165 |
SENP1 | protein found in more fusions | 10 | 0.472 | 7.495 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
166 |
SENP6 | interactor | 2 | 1.000 | 0 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
167 |
SF1 | protein found in more fusions | 15 | 0.374 | 21.593 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
168 |
SF3B3 | interactor | 24 | 0.442 | 40.022 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
169 |
SHMT2 | interactor | 17 | 0.301 | 44.886 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
170 |
SIRT6 | suppressor | 10 | 0.289 | 8.151 | SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
171 |
SIRT7 | interactor | 52 | 0.176 | 507.963 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
172 |
SLC25A5 | interactor | 14 | 0.484 | 5.881 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
173 |
SLC25A6 | interactor | 6 | 0.533 | 0.717 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
174 |
SMARCA5 | interactor | 24 | 0.474 | 35.480 | HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
175 |
SNW1 | protein found in more fusions | 52 | 0.251 | 420.832 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
176 |
SREBF1 | interactor | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
177 |
SRPK2 | oncoprotein | 24 | 0.296 | 80.387 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
178 |
SRPRB | interactor | 9 | 0.306 | 19.545 | MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit |
179 |
SRRM1 | interactor | 15 | 0.581 | 10.293 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
180 |
SRRM2 | interactor | 27 | 0.413 | 56.385 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
181 |
STAC | interactor | 1 | 0 | 0 | SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2 |
182 |
STX5 | interactor | 4 | 0.500 | 2.167 | Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Syntaxin-18_N (PF10496, IPR019529): SNARE-complex protein Syntaxin-18 N-terminus Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain Syntaxin-5_N (PF11416, IPR021538): Syntaxin-5 N-terminal, Sly1p-binding domain |
183 |
SUGP1 | interactor | 4 | 0.500 | 2.167 | G-patch (PF01585, IPR000467, SM00443): G-patch domain Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor MAS20 (PF02064, IPR002056): MAS20 protein import receptor NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region OrfB_IS605 (PF01385, IPR001959): Probable transposase RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB Surp (PF01805, IPR000061, SM00648): Surp module G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site |
184 |
SUPT5H | interactor | 18 | 0.405 | 40.047 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912) |
185 |
SVIL | interactor | 10 | 0.400 | 15.227 | Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) |
186 |
SYNE1 | oncoprotein | 8 | 0.667 | 1.990 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein POX (PF07526, IPR006563, SM00574): Associated with HOX Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat THOC7 (PF05615, IPR008501): Tho complex subunit 7 TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 KASH (PF10541, IPR012315): Nuclear envelope localisation domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416) NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
187 |
TAGLN2 | interactor | 15 | 0.429 | 18.170 | Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain |
188 |
TFIP11 | interactor | 8 | 0.607 | 3.074 | G-patch (PF01585, IPR000467, SM00443): G-patch domain GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein TIP_N (PF12457, IPR022159): Tuftelin interacting protein N terminal |
189 |
THRAP3 | oncoprotein | 14 | 0.451 | 13.004 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
190 |
TIPRL | interactor | 3 | 1.000 | 0 | TIP41 (PF04176, IPR007303): TIP41-like family |
191 |
TMEM201 | interactor | 2 | 1.000 | 0 | DUF1589 (PF07628, IPR011480): Protein of unknown function (DUF1589) Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain DUF2448 (PF10476, IPR018861): Protein of unknown function C-terminus (DUF2448) |
192 |
TMEM230 | interactor | 1 | 0 | 0 | DUF872 (PF05915, IPR008590): Eukaryotic protein of unknown function (DUF872) |
193 |
TMPO | interactor | 27 | 0.302 | 100.045 | LEM (PF03020, IPR003887, SM00540): LEM domain Thymopoietin (PF08198, IPR013146): Thymopoietin protein LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha |
194 |
TOP2A | oncoprotein | 20 | 0.326 | 41.194 | DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec62 (PF03839, IPR004728): Translocation protein Sec62 Toprim (PF01751, IPR006171, SM00493): Toprim domain DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM |
195 |
TOR1A | interactor | 6 | 0.400 | 4.278 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Torsin (PF06309, IPR010448): Torsin |
196 |
TOR1AIP1 | interactor | 10 | 0.289 | 21.109 | LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C) Pap_E4 (PF02711, IPR003861): E4 protein |
197 |
TOX4 | interactor | 4 | 0.667 | 0.222 | Extensin_2 (PF04554, IPR006706): Extensin-like region FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) YABBY (PF04690, IPR006780): YABBY protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
198 |
TP53 | suppressor | 54 | 0.215 | 583.533 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
199 |
TPR | oncoprotein | 19 | 0.515 | 17.775 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
200 |
TPX2 | interactor | 3 | 1.000 | 0 | Aurora-A_bind (PF09041, IPR015128): Aurora-A binding TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259) TPX2_importin (PF12214, IPR027330): Cell cycle regulated microtubule associated protein zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337) |
201 |
TRIM28 | protein found in more fusions | 31 | 0.274 | 123.393 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
202 |
U2SURP | interactor | 14 | 0.505 | 11.270 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB) Surp (PF01805, IPR000061, SM00648): Surp module CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3 FAM176 (PF14851): FAM176 family TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637) |
203 |
UBE2I | interactor | 29 | 0.257 | 149.836 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
204 |
UBE2M | interactor | 13 | 0.530 | 4.527 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
205 |
UCHL5 | oncoprotein | 9 | 0.500 | 8.719 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
206 |
UNC13D | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain Membr_traf_MHD (PF10540, IPR019558): Munc13 (mammalian uncoordinated) homology domain |
207 |
URB2 | interactor | 4 | 0.667 | 0.383 | Urb2 (PF10441, IPR018849): Urb2/Npa2 family |
208 |
USP15 | oncoprotein | 8 | 0.429 | 5.756 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
209 |
USP7 | oncoprotein | 26 | 0.247 | 130.666 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
210 |
VCAM1 | interactor | 33 | 0.258 | 101.047 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
211 |
VCP | protein found in more fusions | 31 | 0.354 | 95.906 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
212 |
VRK2 | interactor | 4 | 0.500 | 1.389 | Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain |
213 |
WDR18 | interactor | 11 | 0.582 | 6.811 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif |
214 |
WDR70 | interactor | 3 | 1.000 | 0 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
215 |
WWOX | suppressor | 16 | 0.267 | 48.432 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
216 |
XRCC6 | oncoprotein | 40 | 0.317 | 193.576 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
217 |
YKT6 | interactor | 4 | 0.500 | 1.867 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |
218 |
YWHAQ | interactor | 29 | 0.426 | 90.012 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
219 |
ZBTB33 | oncoprotein | 5 | 0.500 | 2.211 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
220 |
ZNF239 | oncoprotein | 1 | 0 | 0 | Metallothio_Pro (PF02069, IPR000518): Prokaryotic metallothionein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain Pectate_lyase22 (PF14583, IPR027946): Oligogalacturonate lyase |
221 |
ZNF280C | interactor | 1 | 0 | 0 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding SelR (PF01641, IPR002579): SelR domain zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DUF4195 (PF13836, IPR025243): Domain of unknown function (DUF4195) zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
222 |
ZW10 | interactor | 7 | 0.571 | 6.118 | Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10 DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203) |