Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins LMNA (from a repository: Sun Dec 4 00:46:05 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 222 The number (and %) of the onco-proteins 55 (24.77 %) The number (and %) of the tumor suppressors 28 (12.61 %) Total number of binary PPIs (saturation %) 1802 (7.35 %) The number (and %) of affected PPIs 222 (12.32 %) The number of possible different fusions 33 PPI diameter 2 PPI radius 1 The average degree of PPI 15.586 Assortativity coefficient -0.3048 The network average Clustering coefficient 0.458 The number (and %) of a zero Clustering coefficients 19 (8.56 %) The number (and %) of a zero Betweenness Centrality 44 (19.82 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: LMNA	All fusions : AA852769; AI184403;
Proteins found in more fusions	MME (see 1 fusions); NUP214 (see 1 fusions); CUL7 (see 2 fusions); PPME1 (see 1 fusions); RANGAP1 (see 2 fusions); MYC (see 1 fusions); NUP153 (see 2 fusions); CDH1 (see 3 fusions); PRKDC (see 3 fusions); CTTN (see 1 fusions); PARP1 (see 1 fusions); HCFC1 (see 2 fusions); RPA1 (see 1 fusions); SENP1 (see 1 fusions); TP53 (see 3 fusions); SNW1 (see 1 fusions); ILK (see 1 fusions); ORC2 (see 2 fusions); LMNA (see 3 fusions); VCP (see 4 fusions); TRIM28 (see 1 fusions); SRPK2 (see 1 fusions); EEF1D (see 3 fusions); CD2AP (see 1 fusions); SF1 (see 1 fusions); MCM2 (see 1 fusions); KAT5 (see 3 fusions); NTRK1/TPR (see 1 fusions); PML (see 4 fusions); SYNE1 (see 2 fusions); PCGF2 (see 1 fusions); NCL (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	LMNA	parental protein	222	0.062	31301.838	Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
2	ABCE1	interactor	21	0.321	42.756	ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain
3	ACE	interactor	1	0	0	Peptidase_M2 (PF01401, IPR001548): Angiotensin-converting enzyme
4	AHCTF1	interactor	7	0.524	2.725	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) ELYS (PF13934, IPR025151): Nuclear pore complex assembly ELYS-bb (PF16687, IPR032040): beta-propeller of ELYS nucleoporin
5	ALDH3A2	interactor	2	1.000	0	Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
6	ALOX12	oncoprotein	2	0	0	Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
7	ANKRA2	interactor	6	0.933	0.250	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
8	ANLN	oncoprotein	7	0.429	6.321	Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus
9	ARPIN	interactor	1	0	0	UPF0552 (PF10574, IPR018889): Uncharacterised protein family UPF0552
10	BANF1	interactor	10	0.333	5.195	BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
11	BAZ1B	interactor	9	0.583	1.854	D5_N (PF08706, IPR014818, SM00885): D5 N terminal like DDT (PF02791, IPR004022, SM00571): DDT domain DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PHD (PF00628, IPR019787, SM00249): PHD-finger YL1 (PF05764, IPR008895): YL1 nuclear protein DDRGK (PF09756, IPR019153, SM01128): DDRGK domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635) Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 FAM176 (PF14851): FAM176 family WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
12	BRIP1	oncoprotein	3	0.667	0.667	DEAD_2 (PF06733, IPR010614): DEAD_2 HBB (PF06777, IPR010643): Helical and beta-bridge domain Helicase_C_2 (PF13307, IPR006555): Helicase C-terminal domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
13	C17orf49	interactor	5	0.600	0.987	Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
14	C9orf78	interactor	1	0	0	DHOR (PF06537, IPR010538): Di-haem oxidoreductase, putative peroxidase Hep_59 (PF07052, IPR010756): Hepatocellular carcinoma-associated antigen 59 PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
15	CC2D2A	interactor	2	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain ZnuA (PF01297, IPR006127): Zinc-uptake complex component A periplasmic DUF4240 (PF14024, IPR025334): Protein of unknown function (DUF4240) SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 CC2D2AN-C2 (PF15625, IPR028928): CC2D2A N-terminal C2 domain
16	CCDC47	interactor	4	0.500	1.125	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
17	CCDC8	interactor	53	0.204	436.732	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
18	CD2AP	protein found in more fusions	10	0.333	14.853	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
19	CDC5L	interactor	51	0.257	371.721	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
20	CDH1	suppressor	4	1.000	0	Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
21	CDK16	oncoprotein	4	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
22	CDK2	suppressor	41	0.296	193.848	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
23	CDKAL1	interactor	1	0	0	Radical_SAM (PF04055, IPR007197): Radical SAM superfamily TRAM (PF01938, IPR002792): TRAM domain UPF0004 (PF00919, IPR013848): Uncharacterized protein family UPF0004
24	CHD8	oncoprotein	11	0.382	18.637	BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
25	CISD2	interactor	1	0	0	zf-CDGSH (PF09360, IPR018967, SM00704): Iron-binding zinc finger CDGSH type MitoNEET_N (PF10660, IPR019610): Iron-containing outer mitochondrial membrane protein N-terminus
26	CLK1	interactor	15	0.286	29.436	PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain
27	CPSF6	interactor	16	0.450	25.375	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1
28	CRK	oncoprotein	7	0.524	4.132	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
29	CRKL	oncoprotein	7	0.429	1.874	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
30	CTCF	suppressor	8	0.357	7.188	cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
31	CTNNB1	oncoprotein	31	0.282	151.123	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
32	CTTN	oncoprotein	10	0.583	5.707	FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
33	CUL7	protein found in more fusions	73	0.180	737.757	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
34	CXorf56	interactor	2	1.000	0	DUF4410 (PF14366, IPR025522): Domain of unknown function (DUF4410)
35	DDX3X	suppressor	25	0.390	45.986	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
36	DDX42	interactor	15	0.495	12.058	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
37	DDX46	interactor	11	0.527	4.698	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) CdAMP_rec (PF06153, IPR010375): Cyclic-di-AMP receptor DDRGK (PF09756, IPR019153, SM01128): DDRGK domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAM176 (PF14851): FAM176 family
38	DGCR14	interactor	5	0.600	2.833	Es2 (PF09751, IPR019148): Nuclear protein Es2
39	DNAJC1	interactor	1	0	0	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4234 (PF14018, IPR025328): Domain of unknown function (DUF4234)
40	DUSP13	interactor	1	0	0	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PMAIP1 (PF15150, IPR024140): Phorbol-12-myristate-13-acetate-induced
41	DYNLT1	interactor	8	0.286	16.733	Tctex-1 (PF03645, IPR005334): Tctex-1 family
42	EED	suppressor	52	0.165	408.266	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
43	EEF1D	protein found in more fusions	21	0.311	59.911	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
44	EGF	oncoprotein	7	0.667	3.400	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050)
45	EIF5	interactor	4	0.833	0.051	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
46	EMD	interactor	27	0.329	112.281	LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
47	ENO1	oncoprotein	28	0.384	67.574	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
48	FAM169A	interactor	1	0	0	DUF2464 (PF10240, IPR018798): Protein of unknown function (DUF2464)
49	FAM192A	interactor	3	0.667	0.087	VIT1 (PF01988, IPR008217): VIT family Nefa_Nip30_N (PF10187, IPR019331): N-terminal domain of NEFA-interacting nuclear protein NIP30
50	FASN	interactor	20	0.421	15.930	Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
51	FBXO6	interactor	35	0.185	173.080	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
52	FHL1	suppressor	3	0.667	0.500	LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
53	FLNA	suppressor	30	0.287	124.623	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
54	FN1	oncoprotein	48	0.203	339.883	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
55	FUS	suppressor	34	0.367	111.896	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
56	FYCO1	interactor	5	0.700	0.854	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
57	GMPPB	interactor	1	0	0	Hexapep (PF00132, IPR001451): Bacterial transferase hexapeptide (six repeats) NTP_transferase (PF00483, IPR005835): Nucleotidyl transferase
58	GNL2	interactor	5	0.600	0.184	DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase NGP1NT (PF08153, IPR012971): NGP1NT (NUC091) domain SDA1 (PF05285, IPR007949): SDA1 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
59	GPATCH1	interactor	2	1.000	0	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1604 (PF07713, IPR011666): Protein of unknown function (DUF1604) FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) G-patch (PF01585, IPR000467, SM00443): G-patch domain DUF4598 (PF15370, IPR027921): Domain of unknown function (DUF4598) PIEZO (PF15917, IPR031805): Piezo FAM76 (PF16046, IPR032017): FAM76 protein
60	GPKOW	interactor	3	0.667	0.250	KOW (PF00467, IPR005824, SM00739): KOW motif G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
61	GTF2A1	oncoprotein	3	0.667	0.286	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
62	GTF2F2	interactor	3	1.000	0	TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
63	GZMA	interactor	3	1.000	0	Trypsin (PF00089, IPR001254, SM00020): Trypsin
64	GZMB	interactor	4	0.667	0.900	Trypsin (PF00089, IPR001254, SM00020): Trypsin
65	H2AFX	suppressor	24	0.322	65.378	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
66	H2AFY	interactor	8	0.500	2.475	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Macro (PF01661, IPR002589, SM00506): Macro domain Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
67	HCFC1	protein found in more fusions	11	0.489	8.676	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
68	HERC2	interactor	13	0.470	14.303	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIB_HERC2 (PF06701, IPR010606): Mib_herc2 RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
69	HIST1H3E	interactor	18	0.307	36.750	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
70	HIST1H4G	interactor	1	0	0	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
71	HN1L	interactor	2	1.000	0	JUPITER (PF17054): Microtubule-Associated protein Jupiter
72	HNRNPA0	interactor	17	0.478	13.504	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
73	HNRNPA1	interactor	46	0.394	184.442	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
74	HNRNPA2B1	oncoprotein	26	0.397	39.548	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
75	HNRNPM	interactor	42	0.280	255.926	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
76	HNRNPR	interactor	32	0.355	130.037	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
77	HP1BP3	interactor	12	0.485	5.741	RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SDA1 (PF05285, IPR007949): SDA1 YL1 (PF05764, IPR008895): YL1 nuclear protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
78	ILK	suppressor	22	0.300	65.177	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
79	ING1	suppressor	6	0.467	4.142	PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
80	IRAK1	interactor	7	0.467	3.598	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
81	ISG15	suppressor	13	0.231	20.650	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
82	ITGA4	interactor	42	0.257	187.631	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
83	KAT5	suppressor	20	0.327	75.644	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
84	KCTD12	interactor	3	1.000	0	BTB_2 (PF02214, IPR003131): BTB/POZ domain
85	KIAA0196	interactor	6	0.600	3.800	Strumpellin (PF10266, IPR019393): Hereditary spastic paraplegia protein strumpellin
86	KPNA6	interactor	8	0.393	9.553	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
87	KRTAP10-3	interactor	5	0.667	1.667	Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
88	KRTAP10-7	interactor	8	0.333	12.167	Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein PMG (PF05287, IPR007951): PMG protein DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
89	LBR	interactor	8	0.500	2.567	ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain
90	LEMD3	interactor	3	1.000	0	LEM (PF03020, IPR003887, SM00540): LEM domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
91	LIMK2	interactor	3	0.667	0.250	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain PP1_inhibitor (PF05361, IPR008025): PKC-activated protein phosphatase-1 inhibitor
92	LMNB1	interactor	29	0.330	117.672	Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain
93	LMNB2	interactor	16	0.342	39.305	Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain
94	LRRC59	interactor	11	0.473	4.218	Hid1 (PF12722): High-temperature-induced dauer-formation protein LRR_8 (PF13855, IPR001611): Leucine rich repeat DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
95	MAST3	interactor	8	0.393	2.852	DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus
96	MASTL	interactor	2	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
97	MCM2	oncoprotein	47	0.310	252.442	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
98	MCM3AP	interactor	2	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
99	MCM5	oncoprotein	26	0.406	64.907	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
100	MDC1	suppressor	25	0.370	64.317	FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
101	MKI67	interactor	8	0.607	1.720	FHA (PF00498, IPR000253, SM00240): FHA domain K167R (PF08065, IPR012568): K167R (NUC007) repeat PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding AROS (PF15684, IPR023262): Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1
102	MLIP	interactor	1	0	0	MLIP (PF15274, IPR029331): Muscular LMNA-interacting protein
103	MME	suppressor	6	0.400	4.250	Peptidase_M13 (PF01431, IPR018497): Peptidase family M13 Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
104	MORF4L1	interactor	11	0.556	7.712	MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
105	MORF4L2	interactor	10	0.533	8.070	MRG (PF05712, IPR026541): MRG
106	MOV10	interactor	29	0.197	166.525	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
107	MRE11A	oncoprotein	21	0.547	17.847	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
108	MRGBP	interactor	10	0.378	21.169	Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
109	MRPS26	interactor	4	0.500	0.633	MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
110	MTDH	interactor	4	0.500	1.050	NST1 (PF13945, IPR025279): Salt tolerance down-regulator NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family
111	MYC	oncoprotein	34	0.261	177.724	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
112	NARF	interactor	2	1.000	0	Fe_hyd_lg_C (PF02906, IPR004108): Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU (PF02256, IPR003149, SM00902): Iron hydrogenase small subunit
113	NCL	protein found in more fusions	30	0.342	104.417	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
114	NELFE	interactor	3	1.000	0	DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15
115	NONO	oncoprotein	28	0.373	56.501	GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
116	NPLOC4	interactor	10	0.489	6.856	NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
117	NTRK1	oncoprotein	99	0.109	2525.410	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
118	NUMA1	oncoprotein	22	0.342	47.215	Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
119	NUP133	oncoprotein	17	0.375	37.763	Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal
120	NUP153	protein found in more fusions	23	0.342	75.848	Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
121	NUP155	interactor	12	0.424	5.022	Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
122	NUP214	oncoprotein	13	0.485	5.606	dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159
123	NUP50	interactor	10	0.378	18.140	NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
124	NUP98	suppressor	14	0.484	11.061	Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head
125	NXF1	interactor	42	0.187	338.060	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
126	OBSL1	interactor	79	0.168	949.540	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
127	ORC2	protein found in more fusions	9	0.714	1.114	ORC2 (PF04084, IPR007220): Origin recognition complex subunit 2 DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
128	PAPOLA	interactor	5	0.800	0.515	PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein
129	PARK2	suppressor	18	0.287	27.757	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
130	PARP1	suppressor	31	0.308	111.929	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
131	PCBP1	oncoprotein	21	0.367	35.636	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
132	PCGF2	suppressor	11	0.444	10.205	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
133	PCMT1	interactor	13	0.436	14.195	PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
134	PCNP	interactor	4	0.500	0.887	PCNP (PF15473, IPR029169): PEST, proteolytic signal-containing nuclear protein family
135	PDAP1	interactor	2	1.000	0	PP28 (PF10252, IPR019380): Casein kinase substrate phosphoprotein PP28
136	PDCD5	suppressor	4	0.667	0.587	dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
137	PDLIM3	interactor	1	0	0	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
138	PGRMC2	suppressor	3	0.667	0.050	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
139	PHB	suppressor	19	0.474	17.941	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
140	PML	suppressor	15	0.505	17.071	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
141	PMS2	oncoprotein	4	0.667	1.667	DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
142	POM121	interactor	4	1.000	0	Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region POM121 (PF15229): POM121 family
143	PPM1G	interactor	7	0.619	2.087	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PP2C (PF00481, IPR001932): Protein phosphatase 2C DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
144	PPME1	protein found in more fusions	9	0.536	3.653	Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
145	PPP1CC	oncoprotein	20	0.289	61.559	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
146	PRKCA	interactor	9	0.571	2.412	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
147	PRKDC	protein found in more fusions	40	0.341	165.981	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
148	PSMD10	interactor	7	0.381	8.733	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
149	RANBP2	oncoprotein	29	0.376	77.959	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
150	RANGAP1	protein found in more fusions	17	0.475	21.319	RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain SDA1 (PF05285, IPR007949): SDA1 LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
151	RAPGEF2	interactor	2	1.000	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
152	RB1	suppressor	17	0.426	34.757	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
153	RBBP4	oncoprotein	24	0.308	77.500	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
154	RBM10	interactor	16	0.305	35.577	G-patch (PF01585, IPR000467, SM00443): G-patch domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site zf-C2H2_4 (PF13894): C2H2-type zinc finger DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337) FAM176 (PF14851): FAM176 family
155	RFXANK	interactor	8	0.429	3.362	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
156	RIF1	interactor	12	0.409	14.343	Rif1_N (PF12231, IPR022031): Rap1-interacting factor 1 N terminal DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519) NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
157	RNF113A	interactor	1	0	0	zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8 zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
158	ROCK2	interactor	6	0.733	2.333	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator ZapB (PF06005, IPR009252): Cell division protein ZapB PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain Rho_Binding (PF08912, IPR015008): Rho Binding C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
159	RPA1	suppressor	51	0.262	395.641	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
160	RUVBL1	oncoprotein	31	0.269	160.420	TIP49 (PF06068, IPR010339): TIP49 C-terminus
161	SAP30BP	interactor	7	0.571	2.493	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HCNGP (PF07818, IPR012479): HCNGP-like protein Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
162	SCARNA22	interactor	22	0.281	41.592	NA
163	SCML2	interactor	2	1.000	0	MBT (PF02820, IPR004092, SM00561): mbt repeat SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SLED (PF12140, IPR021987): SLED domain Ashwin (PF15323, IPR024887): Developmental protein RBR (PF17208): RNA binding Region
164	SDCBP	interactor	5	0.600	3.333	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
165	SENP1	protein found in more fusions	10	0.472	7.495	Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
166	SENP6	interactor	2	1.000	0	Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
167	SF1	protein found in more fusions	15	0.374	21.593	UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
168	SF3B3	interactor	24	0.442	40.022	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
169	SHMT2	interactor	17	0.301	44.886	SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
170	SIRT6	suppressor	10	0.289	8.151	SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
171	SIRT7	interactor	52	0.176	507.963	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
172	SLC25A5	interactor	14	0.484	5.881	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
173	SLC25A6	interactor	6	0.533	0.717	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
174	SMARCA5	interactor	24	0.474	35.480	HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
175	SNW1	protein found in more fusions	52	0.251	420.832	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
176	SREBF1	interactor	4	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
177	SRPK2	oncoprotein	24	0.296	80.387	DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
178	SRPRB	interactor	9	0.306	19.545	MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
179	SRRM1	interactor	15	0.581	10.293	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
180	SRRM2	interactor	27	0.413	56.385	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
181	STAC	interactor	1	0	0	SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
182	STX5	interactor	4	0.500	2.167	Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Syntaxin-18_N (PF10496, IPR019529): SNARE-complex protein Syntaxin-18 N-terminus Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain Syntaxin-5_N (PF11416, IPR021538): Syntaxin-5 N-terminal, Sly1p-binding domain
183	SUGP1	interactor	4	0.500	2.167	G-patch (PF01585, IPR000467, SM00443): G-patch domain Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor MAS20 (PF02064, IPR002056): MAS20 protein import receptor NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region OrfB_IS605 (PF01385, IPR001959): Probable transposase RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB Surp (PF01805, IPR000061, SM00648): Surp module G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
184	SUPT5H	interactor	18	0.405	40.047	KOW (PF00467, IPR005824, SM00739): KOW motif Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
185	SVIL	interactor	10	0.400	15.227	Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
186	SYNE1	oncoprotein	8	0.667	1.990	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein POX (PF07526, IPR006563, SM00574): Associated with HOX Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat THOC7 (PF05615, IPR008501): Tho complex subunit 7 TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 KASH (PF10541, IPR012315): Nuclear envelope localisation domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416) NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
187	TAGLN2	interactor	15	0.429	18.170	Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
188	TFIP11	interactor	8	0.607	3.074	G-patch (PF01585, IPR000467, SM00443): G-patch domain GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein TIP_N (PF12457, IPR022159): Tuftelin interacting protein N terminal
189	THRAP3	oncoprotein	14	0.451	13.004	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
190	TIPRL	interactor	3	1.000	0	TIP41 (PF04176, IPR007303): TIP41-like family
191	TMEM201	interactor	2	1.000	0	DUF1589 (PF07628, IPR011480): Protein of unknown function (DUF1589) Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain DUF2448 (PF10476, IPR018861): Protein of unknown function C-terminus (DUF2448)
192	TMEM230	interactor	1	0	0	DUF872 (PF05915, IPR008590): Eukaryotic protein of unknown function (DUF872)
193	TMPO	interactor	27	0.302	100.045	LEM (PF03020, IPR003887, SM00540): LEM domain Thymopoietin (PF08198, IPR013146): Thymopoietin protein LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
194	TOP2A	oncoprotein	20	0.326	41.194	DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec62 (PF03839, IPR004728): Translocation protein Sec62 Toprim (PF01751, IPR006171, SM00493): Toprim domain DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
195	TOR1A	interactor	6	0.400	4.278	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Torsin (PF06309, IPR010448): Torsin
196	TOR1AIP1	interactor	10	0.289	21.109	LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C) Pap_E4 (PF02711, IPR003861): E4 protein
197	TOX4	interactor	4	0.667	0.222	Extensin_2 (PF04554, IPR006706): Extensin-like region FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) YABBY (PF04690, IPR006780): YABBY protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
198	TP53	suppressor	54	0.215	583.533	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
199	TPR	oncoprotein	19	0.515	17.775	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
200	TPX2	interactor	3	1.000	0	Aurora-A_bind (PF09041, IPR015128): Aurora-A binding TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259) TPX2_importin (PF12214, IPR027330): Cell cycle regulated microtubule associated protein zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
201	TRIM28	protein found in more fusions	31	0.274	123.393	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
202	U2SURP	interactor	14	0.505	11.270	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB) Surp (PF01805, IPR000061, SM00648): Surp module CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3 FAM176 (PF14851): FAM176 family TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637)
203	UBE2I	interactor	29	0.257	149.836	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
204	UBE2M	interactor	13	0.530	4.527	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
205	UCHL5	oncoprotein	9	0.500	8.719	Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
206	UNC13D	interactor	1	0	0	C2 (PF00168, IPR000008, SM00239): C2 domain Membr_traf_MHD (PF10540, IPR019558): Munc13 (mammalian uncoordinated) homology domain
207	URB2	interactor	4	0.667	0.383	Urb2 (PF10441, IPR018849): Urb2/Npa2 family
208	USP15	oncoprotein	8	0.429	5.756	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
209	USP7	oncoprotein	26	0.247	130.666	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
210	VCAM1	interactor	33	0.258	101.047	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
211	VCP	protein found in more fusions	31	0.354	95.906	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
212	VRK2	interactor	4	0.500	1.389	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain
213	WDR18	interactor	11	0.582	6.811	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
214	WDR70	interactor	3	1.000	0	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
215	WWOX	suppressor	16	0.267	48.432	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain
216	XRCC6	oncoprotein	40	0.317	193.576	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
217	YKT6	interactor	4	0.500	1.867	Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain
218	YWHAQ	interactor	29	0.426	90.012	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
219	ZBTB33	oncoprotein	5	0.500	2.211	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
220	ZNF239	oncoprotein	1	0	0	Metallothio_Pro (PF02069, IPR000518): Prokaryotic metallothionein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain Pectate_lyase22 (PF14583, IPR027946): Oligogalacturonate lyase
221	ZNF280C	interactor	1	0	0	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding SelR (PF01641, IPR002579): SelR domain zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DUF4195 (PF13836, IPR025243): Domain of unknown function (DUF4195) zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
222	ZW10	interactor	7	0.571	6.118	Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10 DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)

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