1 |
KHDRBS1 | parental protein | 161 | 0.069 | 17919.823 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
2 |
ABI2 | suppressor | 5 | 0.833 | 0.333 | Abi_HHR (PF07815, IPR012849): Abl-interactor HHR NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region SH3_9 (PF14604, IPR001452): Variant SH3 domain TMEM171 (PF15471, IPR029173): Transmembrane protein family 171 ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension |
3 |
ACTB | oncoprotein | 26 | 0.243 | 148.038 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
AGO1 | interactor | 6 | 0.467 | 5.011 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
5 |
AHI1 | oncoprotein | 1 | 0 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
6 |
AMPH | oncoprotein | 3 | 1.000 | 0 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus |
7 |
APBB1 | interactor | 9 | 0.714 | 1.466 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
8 |
ARHGEF4 | oncoprotein | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
9 |
ARHGEF9 | interactor | 2 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
10 |
ATXN2 | interactor | 12 | 0.545 | 9.036 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Spt20 (PF12090, IPR021950): Spt20 family SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
11 |
ATXN2L | interactor | 7 | 0.619 | 3.686 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
12 |
AZIN1 | interactor | 1 | 0 | 0 | Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain |
13 |
BAIAP2L1 | interactor | 2 | 1.000 | 0 | IMD (PF08397, IPR013606): IRSp53/MIM homology domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c SH3_9 (PF14604, IPR001452): Variant SH3 domain |
14 |
BANP | suppressor | 3 | 1.000 | 0 | DUF1845 (PF08900, IPR014996): Domain of unknown function (DUF1845) BEN (PF10523, IPR018379, SM01025): BEN domain |
15 |
BMI1 | oncoprotein | 21 | 0.221 | 90.889 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
16 |
BTK | suppressor | 10 | 0.389 | 11.349 | BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
17 |
CAND1 | interactor | 30 | 0.539 | 53.195 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
18 |
CASP8 | suppressor | 7 | 0.600 | 4.333 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
19 |
CBX6 | interactor | 4 | 0.667 | 1.667 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain CBX7_C (PF17218): CBX family C-terminal motif |
20 |
CCDC8 | interactor | 23 | 0.424 | 74.550 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
21 |
CD2AP | protein found in more fusions | 5 | 0.667 | 0.686 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil |
22 |
CD81 | interactor | 14 | 0.500 | 14.131 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
23 |
CDC5L | interactor | 33 | 0.490 | 113.337 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
24 |
CIRBP | oncoprotein | 11 | 0.673 | 3.647 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
25 |
CLK1 | interactor | 11 | 0.600 | 5.922 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
26 |
COPA | protein found in more fusions | 17 | 0.450 | 24.434 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region COPI_C (PF06957, IPR010714): Coatomer (COPI) alpha subunit C-terminus WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
27 |
CREB3L3 | interactor | 2 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
28 |
CREBBP | suppressor | 16 | 0.333 | 42.191 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
29 |
CRK | oncoprotein | 14 | 0.308 | 38.313 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
30 |
CRKL | oncoprotein | 7 | 0.429 | 6.222 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
31 |
CRY1 | interactor | 7 | 0.600 | 1.379 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
32 |
CRY2 | protein found in more fusions | 13 | 0.409 | 15.870 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
33 |
CSK | interactor | 10 | 0.422 | 16.369 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
34 |
CUL3 | protein found in more fusions | 45 | 0.326 | 342.742 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
35 |
CUL7 | protein found in more fusions | 29 | 0.526 | 65.953 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
36 |
DDX17 | protein found in more fusions | 37 | 0.422 | 126.182 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
37 |
DDX5 | oncoprotein | 38 | 0.429 | 133.203 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
38 |
DHX15 | interactor | 30 | 0.508 | 62.798 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
39 |
DHX9 | oncoprotein | 35 | 0.477 | 97.229 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
40 |
DLG1 | suppressor | 4 | 0.500 | 2.400 | L27_1 (PF09058, IPR015143): L27_1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
41 |
DLG2 | interactor | 2 | 1.000 | 0 | Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein L27_1 (PF09058, IPR015143): L27_1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
42 |
DLG3 | interactor | 3 | 0.667 | 1.000 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
43 |
DLG4 | protein found in more fusions | 6 | 0.400 | 5.667 | L27_1 (PF09058, IPR015143): L27_1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
44 |
DNMBP | interactor | 2 | 1.000 | 0 | BAR (PF03114, IPR004148, SM00721): BAR domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat IncA (PF04156, IPR007285): IncA protein RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
45 |
DOCK2 | oncoprotein | 6 | 0.533 | 3.722 | DHR-2 (PF06920, IPR010703): Dock homology region 2 DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins SH3_9 (PF14604, IPR001452): Variant SH3 domain DOCK_N (PF16172, IPR032376): DOCK N-terminus |
46 |
DOCK3 | interactor | 2 | 1.000 | 0 | DHR-2 (PF06920, IPR010703): Dock homology region 2 SH3_2 (PF07653, IPR011511): Variant SH3 domain MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins DOCK_N (PF16172, IPR032376): DOCK N-terminus |
47 |
DROSHA | interactor | 7 | 0.524 | 5.034 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain Ribonucleas_3_3 (PF14622, IPR000999): Ribonuclease-III-like DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
48 |
EFEMP1 | interactor | 1 | 0 | 0 | EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
49 |
EMG1 | interactor | 5 | 0.700 | 0.335 | EMG1 (PF03587, IPR005304): EMG1/NEP1 methyltransferase |
50 |
ESR1 | suppressor | 35 | 0.310 | 203.066 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
51 |
EWSR1 | oncoprotein | 36 | 0.282 | 235.107 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
52 |
EZH2 | suppressor | 15 | 0.429 | 26.295 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
53 |
FADD | suppressor | 5 | 0.800 | 1.000 | Death (PF00531, IPR000488, SM00005): Death domain DED (PF01335, IPR001875, SM00031): Death effector domain Hpt (PF01627, IPR008207, SM00073): Hpt domain |
54 |
FBXW11 | interactor | 13 | 0.530 | 8.586 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
55 |
FGR | oncoprotein | 3 | 0.667 | 0.250 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
56 |
FNBP4 | oncoprotein | 5 | 0.500 | 3.233 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) WW (PF00397, IPR001202, SM00456): WW domain DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637) |
57 |
FRK | suppressor | 3 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
58 |
FYN | oncoprotein | 18 | 0.250 | 70.071 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
59 |
GAS7 | oncoprotein | 4 | 0.667 | 0.667 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain WW (PF00397, IPR001202, SM00456): WW domain YscO (PF07321, IPR009929): Type III secretion protein YscO SH3_9 (PF14604, IPR001452): Variant SH3 domain WW_FCH_linker (PF16623): Unstructured linker region between on GAS7 protein |
60 |
GLRX3 | interactor | 4 | 1.000 | 0 | Glutaredoxin (PF00462, IPR002109): Glutaredoxin Thioredoxin (PF00085, IPR013766): Thioredoxin TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding |
61 |
GPHN | oncoprotein | 4 | 0.667 | 1.000 | MoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain MoeA_C (PF03454, IPR005111): MoeA C-terminal region (domain IV) MoeA_N (PF03453, IPR005110): MoeA N-terminal region (domain I and II) Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat |
62 |
GRAP2 | interactor | 2 | 1.000 | 0 | NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
63 |
GRB2 | oncoprotein | 31 | 0.239 | 213.099 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
64 |
HCK | oncoprotein | 10 | 0.400 | 12.055 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
65 |
HDAC6 | oncoprotein | 7 | 0.400 | 6.654 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
66 |
HIST1H3E | interactor | 4 | 0.833 | 0.400 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
67 |
HNRNPA1 | interactor | 39 | 0.505 | 94.638 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
68 |
HNRNPC | protein found in more fusions | 25 | 0.536 | 38.241 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
69 |
HNRNPK | oncoprotein | 51 | 0.278 | 520.531 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
70 |
HNRNPR | interactor | 34 | 0.513 | 97.364 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
71 |
INSR | interactor | 11 | 0.455 | 17.919 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain |
72 |
IRS1 | interactor | 7 | 0.476 | 5.350 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
73 |
ITK | oncoprotein | 7 | 0.667 | 1.600 | BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
74 |
ITSN1 | interactor | 9 | 0.393 | 14.133 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
75 |
ITSN2 | protein found in more fusions | 10 | 0.361 | 17.408 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
76 |
KHDRBS2 | interactor | 20 | 0.409 | 48.175 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
77 |
KHDRBS3 | interactor | 16 | 0.457 | 23.228 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
78 |
LCK | oncoprotein | 8 | 0.381 | 8.217 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
79 |
LGR4 | interactor | 8 | 0.619 | 4.136 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
80 |
LYN | oncoprotein | 14 | 0.333 | 28.406 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
81 |
MATR3 | interactor | 34 | 0.439 | 120.739 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
82 |
MIA2 | suppressor | 1 | 0 | 0 | NESP55 (PF06390, IPR009434): Neuroendocrine-specific golgi protein P55 (NESP55) SH3_2 (PF07653, IPR011511): Variant SH3 domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
83 |
MPHOSPH8 | protein found in more fusions | 4 | 0.667 | 0.286 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat Ank_5 (PF13857): Ankyrin repeats (many copies) YqzE (PF14038, IPR025622): YqzE-like protein |
84 |
MPP6 | interactor | 3 | 1.000 | 0 | L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
85 |
MYO1C | interactor | 11 | 0.436 | 14.078 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
86 |
MYO7A | interactor | 1 | 0 | 0 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) SH3_9 (PF14604, IPR001452): Variant SH3 domain |
87 |
NCF1 | interactor | 3 | 1.000 | 0 | p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 |
88 |
NCK1 | oncoprotein | 9 | 0.389 | 13.883 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
89 |
NCK2 | interactor | 10 | 0.306 | 17.289 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
90 |
NCKIPSD | oncoprotein | 5 | 0.700 | 1.667 | DUF2013 (PF09431, IPR018556): Protein of unknown function (DUF2013) Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
91 |
NCSTN | interactor | 4 | 0.833 | 0.105 | Nicastrin (PF05450, IPR008710): Nicastrin Ost4 (PF10215, IPR018943): Oligosaccaryltransferase |
92 |
NPHP1 | interactor | 6 | 0.400 | 5.500 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FAM176 (PF14851): FAM176 family Speriolin_N (PF15058, IPR029385): Speriolin N terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
93 |
NTRK1 | oncoprotein | 56 | 0.212 | 785.995 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
94 |
OBSL1 | interactor | 30 | 0.483 | 68.555 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
95 |
OSTF1 | interactor | 3 | 0.667 | 0.286 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
96 |
PACSIN1 | interactor | 6 | 0.600 | 3.333 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446) SH3_9 (PF14604, IPR001452): Variant SH3 domain NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif |
97 |
PACSIN2 | oncoprotein | 6 | 0.600 | 3.000 | DegS (PF05384, IPR008595): Sensor protein DegS FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3BP5 (PF05276, IPR007940): SH3 domain-binding protein 5 (SH3BP5) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif |
98 |
PACSIN3 | interactor | 6 | 0.500 | 4.667 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain GrpE (PF01025, IPR000740): GrpE SH3_9 (PF14604, IPR001452): Variant SH3 domain |
99 |
PIK3R1 | oncoprotein | 18 | 0.353 | 50.262 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
100 |
PIK3R3 | interactor | 11 | 0.473 | 14.586 | SH2 (PF00017, IPR000980, SM00252): SH2 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
101 |
PLCG1 | oncoprotein | 9 | 0.667 | 4.971 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
102 |
POT1 | interactor | 10 | 0.278 | 19.067 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
103 |
PPP1CB | interactor | 14 | 0.374 | 34.309 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
104 |
PPP1R13B | interactor | 3 | 0.667 | 0.250 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) IncA (PF04156, IPR007285): IncA protein RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
105 |
PRMT1 | interactor | 21 | 0.500 | 32.089 | Methyltransf_25 (PF13649): Methyltransferase domain |
106 |
PSTPIP1 | interactor | 2 | 1.000 | 0 | ABATE (PF07336, IPR010852): Putative stress-induced transcription regulator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 |
107 |
PTBP2 | interactor | 6 | 0.700 | 0.591 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
108 |
PTK6 | interactor | 3 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
109 |
RALY | interactor | 24 | 0.587 | 35.494 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
110 |
RAPSN | interactor | 1 | 0 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat |
111 |
RASA1 | oncoprotein | 12 | 0.379 | 28.540 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
112 |
RBFOX2 | protein found in more fusions | 14 | 0.654 | 5.645 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal |
113 |
RBM15 | oncoprotein | 13 | 0.538 | 8.064 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC (PF07744, IPR012921): SPOC domain Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain |
114 |
RBM7 | interactor | 8 | 0.714 | 1.590 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
115 |
RBMX | suppressor | 32 | 0.477 | 83.028 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
116 |
RIPK1 | protein found in more fusions | 5 | 1.000 | 0 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RHIM (PF12721, IPR025735): RIP homotypic interaction motif |
117 |
RNF2 | interactor | 21 | 0.542 | 31.283 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
118 |
RPA1 | suppressor | 31 | 0.469 | 86.115 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
119 |
RPA2 | oncoprotein | 25 | 0.483 | 48.338 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
120 |
RPA3 | interactor | 24 | 0.549 | 26.586 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
121 |
RUSC2 | interactor | 1 | 0 | 0 | RUN (PF02759, IPR004012, SM00593): RUN domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
122 |
SASH1 | suppressor | 2 | 1.000 | 0 | PGA2 (PF07543, IPR011431): Protein trafficking PGA2 SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SH3_2 (PF07653, IPR011511): Variant SH3 domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) SLY (PF12485, IPR021090): Lymphocyte signaling adaptor protein |
123 |
SCG5 | interactor | 1 | 0 | 0 | Secretogranin_V (PF05281, IPR007945): Neuroendocrine protein 7B2 precursor (Secretogranin V) |
124 |
SFPQ | oncoprotein | 28 | 0.342 | 116.576 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
125 |
SH3GL1 | oncoprotein | 7 | 0.533 | 3.682 | BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
126 |
SH3KBP1 | protein found in more fusions | 21 | 0.242 | 94.570 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
127 |
SH3PXD2A | interactor | 3 | 1.000 | 0 | DUF1604 (PF07713, IPR011666): Protein of unknown function (DUF1604) PX (PF00787, IPR001683, SM00312): PX domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain hSH3 (PF14603, IPR029294): Helically-extended SH3 domain |
128 |
SH3YL1 | interactor | 1 | 0 | 0 | Ysc84 (PF04366, IPR007461): Las17-binding protein actin regulator SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
129 |
SKAP2 | interactor | 6 | 0.600 | 1.452 | PH (PF00169, IPR001849, SM00233): PH domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_9 (PF15410): Pleckstrin homology domain PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
130 |
SMAD2 | suppressor | 9 | 0.393 | 11.244 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
131 |
SMARCA2 | suppressor | 6 | 0.600 | 1.942 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
132 |
SMARCAD1 | interactor | 11 | 0.927 | 0.388 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
133 |
SNW1 | protein found in more fusions | 34 | 0.460 | 112.997 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
134 |
SNX30 | interactor | 1 | 0 | 0 | BAR (PF03114, IPR004148, SM00721): BAR domain PX (PF00787, IPR001683, SM00312): PX domain |
135 |
SNX9 | protein found in more fusions | 7 | 0.467 | 5.180 | PX (PF00787, IPR001683, SM00312): PX domain BAR_3_WASP_bdg (PF10456, IPR019497): WASP-binding domain of Sorting nexin protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
136 |
SORBS1 | interactor | 6 | 0.467 | 5.286 | SH3_2 (PF07653, IPR011511): Variant SH3 domain Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein |
137 |
SPATA13 | interactor | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
138 |
SRC | oncoprotein | 26 | 0.270 | 142.602 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
139 |
SRPK2 | oncoprotein | 24 | 0.431 | 71.060 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
140 |
SRRM1 | interactor | 18 | 0.634 | 14.014 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
141 |
SRSF3 | oncoprotein | 24 | 0.493 | 40.789 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
142 |
SSFA2 | interactor | 4 | 0.667 | 0.733 | KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus |
143 |
STAT3 | suppressor | 14 | 0.410 | 26.155 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
144 |
STUB1 | suppressor | 8 | 0.381 | 9.067 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
145 |
SUZ12 | suppressor | 17 | 0.492 | 21.684 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
146 |
SYNCRIP | interactor | 33 | 0.413 | 134.554 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
147 |
TBL1X | protein found in more fusions | 2 | 0 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family |
148 |
TJP1 | interactor | 8 | 0.500 | 4.192 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal |
149 |
TNFRSF1A | oncoprotein | 11 | 0.489 | 17.452 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
150 |
TSPOAP1 | oncoprotein | 2 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain ZapB (PF06005, IPR009252): Cell division protein ZapB fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SlyX (PF04102, IPR007236): SlyX DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding SH3_9 (PF14604, IPR001452): Variant SH3 domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
151 |
TUBB3 | interactor | 8 | 0.536 | 5.490 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
152 |
U2AF2 | protein found in more fusions | 35 | 0.535 | 73.818 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
153 |
UBASH3B | interactor | 9 | 0.536 | 6.656 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
154 |
USO1 | interactor | 4 | 1.000 | 0 | Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Uso1_p115_head (PF04869, IPR006953): Uso1 / p115 like vesicle tethering protein, head region Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain MutS_III (PF05192, IPR007696, SM00533): MutS domain III ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding MG1 (PF11974, IPR021868): Alpha-2-macroglobulin MG1 domain TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding |
155 |
VAV1 | oncoprotein | 11 | 0.364 | 22.763 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain |
156 |
WBP11 | interactor | 14 | 0.341 | 33.826 | BUD22 (PF09073, IPR015158): BUD22 Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SspB (PF04386, IPR007481): Stringent starvation protein B Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ABC_trans_N (PF14510, IPR029481): ABC-transporter extracellular N-terminal |
157 |
WBP4 | interactor | 6 | 0.533 | 1.058 | CDC45 (PF02724, IPR003874): CDC45-like protein WW (PF00397, IPR001202, SM00456): WW domain zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger TMCO5 (PF14992, IPR026617): TMCO5 family |
158 |
YES1 | oncoprotein | 5 | 0.400 | 4.119 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
159 |
YTHDC1 | interactor | 10 | 0.600 | 7.486 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family YTH (PF04146, IPR007275): YT521-B-like domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH |
160 |
ZBTB7A | interactor | 2 | 0 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GAGA (PF09237, IPR015318): GAGA factor zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
161 |
ZDHHC6 | interactor | 1 | 0 | 0 | SH3_2 (PF07653, IPR011511): Variant SH3 domain zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase |