Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins KDELR1 (from a repository: Sat Nov 12 16:42:47 2016)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins4 (36.36 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)19 (34.55 %)
The number (and %) of affected PPIs11 (57.89 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI2.364
Assortativity coefficient-0.2775
The network average Clustering coefficient0.430
The number (and %) of a zero Clustering coefficients5 (45.45 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)


List of the fusions

PPI for parental proteins: KDELR1 All fusions
: AI826978; CN300933;
Proteins found in more fusions KDELR1 (see 2 fusions); MCM2 (see 1 fusions); ARF1 (see 2 fusions); COPB1 (see 2 fusions); SEC23B (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 KDELR1parental protein110.06783.000ER_lumen_recept (PF00810, IPR000133): ER lumen protein retaining receptor
2 ARF1suppressor40.6671.000Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
3 ARFGAP1interactor21.0000ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
4 BZW1interactor100W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
5 COPB1protein found in more fusions31.0000Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
6 LIG4interactor100APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
7 MCM2oncoprotein31.0000AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
8 NEK6interactor200Pkinase (PF00069, IPR000719): Protein kinase domain
9 SEC23Bprotein found in more fusions31.0000Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
10 SERINC3oncoprotein100Serinc (PF03348, IPR005016): Serine incorporator (Serinc)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
11 TCEAL9interactor100BEX (PF04538, IPR021156): Brain expressed X-linked like family

B a c k    t o    T o p ⇑