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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins KCNN2 (from a repository: Tue Dec 6 10:16:31 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins2 (40.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)8 (80.00 %)
The number (and %) of affected PPIs5 (62.50 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.4082
The network average Clustering coefficient0.433
The number (and %) of a zero Clustering coefficients2 (40.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: KCNN2 All fusions
Proteins found in more fusions ACTN2 (see 1 fusions); KCNN2 (see 1 fusions); SRPK2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 KCNN2parental protein50.16710.000CaMBD (PF02888, IPR004178, SM01053): Calmodulin binding domain
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
Ion_trans_2 (PF07885, IPR013099): Ion channel
PMP1_2 (PF08114, IPR012589): ATPase proteolipid family
SK_channel (PF03530, IPR015449): Calcium-activated SK potassium channel
2 ACTN2protein found in more fusions200CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
3 CALM1interactor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
4 SRPK1interactor21.0000FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
5 SRPK2oncoprotein31.0000DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)

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