1 |
KAT8 | parental protein | 39 | 0.132 | 931.494 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
2 |
ATM | suppressor | 5 | 1.000 | 0 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
3 |
BAZ2A | interactor | 2 | 1.000 | 0 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DDHD (PF02862, IPR004177, SM01127): DDHD domain DDT (PF02791, IPR004022, SM00571): DDT domain MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain PHD (PF00628, IPR019787, SM00249): PHD-finger RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif |
4 |
BRD4 | oncoprotein | 6 | 0.800 | 1.667 | Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
5 |
CCAR2 | suppressor | 5 | 0.500 | 4.000 | DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide IncA (PF04156, IPR007285): IncA protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 DBC1 (PF14443, IPR025954, SM01122): DBC1 S1-like (PF14444, IPR025223): S1-like |
6 |
DYRK1B | oncoprotein | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
7 |
FOXP3 | suppressor | 3 | 1.000 | 0 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
8 |
H2AFX | suppressor | 10 | 0.600 | 9.541 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
9 |
HCFC1 | protein found in more fusions | 7 | 0.667 | 4.000 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
10 |
HECW2 | interactor | 5 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
11 |
HIST1H2BG | oncoprotein | 4 | 0.667 | 0.900 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
12 |
HIST1H3A | interactor | 15 | 0.363 | 38.900 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
13 |
HIST1H4A | interactor | 11 | 0.455 | 19.719 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
14 |
HNRNPA1 | interactor | 9 | 0.607 | 7.800 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
15 |
KANSL1 | interactor | 3 | 1.000 | 0 | PEHE (PF15275, IPR029332): PEHE domain |
16 |
KMT2A | oncoprotein | 12 | 0.400 | 24.908 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
17 |
MCRS1 | interactor | 1 | 0 | 0 | FHA (PF00498, IPR000253, SM00240): FHA domain MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein |
18 |
MORF4L1 | interactor | 3 | 1.000 | 0 | MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
19 |
MSL1 | interactor | 8 | 0.464 | 12.952 | Herpes_UL6 (PF01763, IPR002660): Herpesvirus UL6 like KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein PEHE (PF15275, IPR029332): PEHE domain MSL1_dimer (PF16801, IPR031840): Dimerisation domain of Male-specific-Lethal 1 |
20 |
MSL2 | interactor | 8 | 0.571 | 7.186 | MSL2-CXC (PF16682, IPR032049): CXC domain of E3 ubiquitin-protein ligase MSL2 zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
21 |
MSL3 | interactor | 9 | 0.472 | 14.019 | GET2 (PF08690, IPR028143): GET complex subunit GET2 MRG (PF05712, IPR026541): MRG Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
22 |
MSL3P1 | interactor | 2 | 1.000 | 0 | NA |
23 |
OGT | interactor | 3 | 1.000 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41 TPR_19 (PF14559): Tetratricopeptide repeat |
24 |
PAF1 | oncoprotein | 6 | 0.733 | 1.686 | Paf1 (PF03985, IPR007133): Paf1 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
25 |
PHF20 | oncoprotein | 4 | 0.667 | 0.508 | GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776) |
26 |
PHF20L1 | interactor | 1 | 0 | 0 | MBT (PF02820, IPR004092, SM00561): mbt repeat PHD (PF00628, IPR019787, SM00249): PHD-finger U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776) CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PEHE (PF15275, IPR029332): PEHE domain EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1 |
27 |
PLK1 | suppressor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region |
28 |
PPP1CB | interactor | 4 | 0.833 | 0.667 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
29 |
PRKDC | protein found in more fusions | 9 | 0.500 | 10.956 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
30 |
RBBP5 | oncoprotein | 8 | 0.571 | 7.000 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
31 |
RNF2 | interactor | 8 | 0.667 | 4.067 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
32 |
SIRT1 | suppressor | 7 | 0.467 | 6.222 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
33 |
TCEB3 | suppressor | 3 | 1.000 | 0 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain |
34 |
TNK2 | interactor | 3 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GTPase_binding (PF09027, IPR015116): GTPase binding Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 UBA_4 (PF14555): UBA-like domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
35 |
TP53 | suppressor | 18 | 0.272 | 80.100 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
36 |
TPR | oncoprotein | 2 | 1.000 | 0 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
37 |
WDR5 | interactor | 9 | 0.500 | 13.056 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
38 |
YWHAE | oncoprotein | 10 | 0.600 | 9.327 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
39 |
YWHAZ | protein found in more fusions | 11 | 0.600 | 9.327 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |