Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins KAT2B (from a repository: Wed Nov 16 23:13:24 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 175 The number (and %) of the onco-proteins 64 (36.57 %) The number (and %) of the tumor suppressors 39 (22.29 %) Total number of binary PPIs (saturation %) 1240 (8.14 %) The number (and %) of affected PPIs 175 (14.11 %) The number of possible different fusions 33 PPI diameter 2 PPI radius 1 The average degree of PPI 13.383 Assortativity coefficient -0.2539 The network average Clustering coefficient 0.550 The number (and %) of a zero Clustering coefficients 5 (2.86 %) The number (and %) of a zero Betweenness Centrality 26 (14.86 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: KAT2B	All fusions
Proteins found in more fusions	CTBP1 (see 2 fusions); SMARCB1 (see 12 fusions); CTBP2 (see 2 fusions); VHL (see 1 fusions); MYC (see 1 fusions); MAPRE1 (see 1 fusions); KIF11 (see 1 fusions); KAT2B (see 1 fusions); ACTB (see 3 fusions); XBP1 (see 2 fusions); RARA (see 4 fusions); ACTN2 (see 1 fusions); HTT (see 1 fusions); PARP1 (see 1 fusions); EP300 (see 1 fusions); CCND1 (see 1 fusions); TP53 (see 3 fusions); MED21 (see 1 fusions); ACTN1 (see 3 fusions); NCOA1 (see 2 fusions); USF1 (see 3 fusions); YY1 (see 2 fusions); MAPK14 (see 1 fusions); CREBBP (see 5 fusions); HNRNPD (see 1 fusions); TCF3 (see 3 fusions); MYOD1 (see 1 fusions); POLR2A (see 2 fusions); SIAH2 (see 1 fusions); DDX17 (see 3 fusions); EZH2 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	KAT2B	parental protein	175	0.066	18317.722	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
2	ACLY	interactor	1	0	0	ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding
3	ACTB	oncoprotein	22	0.367	81.241	Actin (PF00022, IPR004000, SM00268): Actin
4	ACTN1	protein found in more fusions	7	0.467	6.667	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation
5	ACTN2	protein found in more fusions	3	1.000	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
6	AKT1	oncoprotein	26	0.333	92.335	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7	AR	oncoprotein	30	0.335	138.472	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
8	ARNTL	suppressor	9	0.694	3.989	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain
9	ATF4	oncoprotein	8	0.619	7.000	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
10	ATXN3	interactor	7	0.800	0.626	Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
11	ATXN7L3	interactor	14	0.505	33.564	SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
12	BCAS3	oncoprotein	5	0.500	1.971	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat BCAS3 (PF12490, IPR022175): Breast carcinoma amplified sequence 3
13	BRCA2	suppressor	9	0.528	9.269	BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower
14	BUB1B	oncoprotein	7	0.533	2.175	Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
15	CARM1	oncoprotein	19	0.380	44.466	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
16	CCNA2	oncoprotein	18	0.463	32.520	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
17	CCND1	oncoprotein	16	0.495	25.719	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
18	CCNT1	oncoprotein	5	0.833	0.333	Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor
19	CDC25B	oncoprotein	5	0.500	1.532	M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
20	CDCA4	interactor	2	1.000	0	SERTA (PF06031, IPR009263): SERTA motif
21	CDK2	suppressor	47	0.201	527.392	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
22	CDK8	interactor	19	0.464	31.538	Pkinase (PF00069, IPR000719): Protein kinase domain
23	CDKN1A	suppressor	23	0.395	66.852	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
24	CDKN1B	suppressor	10	0.467	9.890	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
25	CDT1	oncoprotein	7	0.667	2.767	CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
26	CEBPB	oncoprotein	19	0.444	33.721	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
27	CEP250	interactor	5	0.500	2.869	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
28	CHEK2	suppressor	10	0.500	8.658	FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain
29	CLOCK	interactor	7	0.905	0.505	DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain
30	CREBBP	suppressor	74	0.155	1314.195	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
31	CTBP1	protein found in more fusions	21	0.358	66.719	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
32	CTBP2	protein found in more fusions	12	0.473	17.088	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
33	CTNNB1	oncoprotein	26	0.289	110.299	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
34	CUX1	suppressor	9	0.278	17.821	Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein CUT (PF02376, IPR003350, SM01109): CUT domain DegS (PF05384, IPR008595): Sensor protein DegS DivIC (PF04977, IPR007060): Septum formation initiator DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Swi5 (PF07061, IPR010760): Swi5 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ApoO (PF09769, IPR019166): Apolipoprotein O Homeobox (PF00046, IPR001356, SM00389): Homeobox domain RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
35	DDX17	protein found in more fusions	13	0.470	16.410	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
36	DEK	oncoprotein	11	0.564	12.458	DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
37	DR1	interactor	8	0.786	4.667	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone SLED (PF12140, IPR021987): SLED domain
38	E2F1	suppressor	15	0.571	11.501	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
39	EHMT2	interactor	16	0.286	41.795	CDC45 (PF02724, IPR003874): CDC45-like protein Pre-SET (PF05033, IPR007728): Pre-SET motif Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family SET (PF00856, IPR001214, SM00317): SET domain SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
40	EP300	oncoprotein	94	0.134	2357.063	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
41	ERCC6	oncoprotein	12	0.348	20.286	Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
42	ESRRA	oncoprotein	4	0.667	0.422	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
43	ETS1	oncoprotein	12	0.712	6.721	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
44	ETV1	oncoprotein	6	0.867	0.295	Ets (PF00178, IPR000418, SM00413): Ets-domain ETS_PEA3_N (PF04621, IPR006715): PEA3 subfamily ETS-domain transcription factor N terminal domain
45	EZH2	suppressor	21	0.279	68.590	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
46	FLI1	oncoprotein	4	0.667	1.500	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
47	GLI1	suppressor	6	0.667	4.286	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
48	H2AFX	suppressor	16	0.275	44.135	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
49	H3F3A	oncoprotein	10	0.289	17.838	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
50	HDAC3	suppressor	30	0.296	126.629	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
51	HIF1A	suppressor	24	0.413	65.350	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
52	HIST1H1A	interactor	10	0.467	10.348	Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
53	HIST1H1B	oncoprotein	8	0.500	7.802	Pneumo_att_G (PF05539, IPR008781): Pneumovirinae attachment membrane glycoprotein G Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
54	HIST1H2AB	interactor	7	0.524	3.683	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
55	HIST1H2BB	interactor	7	0.810	0.882	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
56	HIST1H3A	interactor	26	0.250	135.965	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
57	HIST1H4A	interactor	15	0.533	18.957	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
58	HIST2H2AC	interactor	12	0.470	21.909	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
59	HIST2H2BE	interactor	14	0.462	23.525	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
60	HIST2H3C	interactor	7	0.429	4.812	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
61	HIST3H3	interactor	24	0.315	116.935	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
62	HIST4H4	interactor	11	0.400	13.612	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
63	HMGA1	oncoprotein	13	0.462	17.753	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
64	HMGN2	interactor	4	1.000	0	HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17
65	HNF1A	oncoprotein	8	0.667	1.503	HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
66	HNRNPD	oncoprotein	12	0.491	14.979	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
67	HNRNPU	interactor	20	0.321	83.977	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
68	HOXA10	interactor	5	0.500	2.098	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266)
69	HSD11B2	interactor	2	1.000	0	adh_short (PF00106, IPR002198): short chain dehydrogenase DUF1776 (PF08643, IPR013952): Fungal family of unknown function (DUF1776)
70	HSPA4	interactor	13	0.538	8.771	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
71	HTT	protein found in more fusions	10	0.556	7.314	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
72	ING1	suppressor	9	0.556	5.566	PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
73	IRF1	suppressor	8	0.536	6.590	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
74	IRF2	interactor	4	1.000	0	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
75	IRF5	suppressor	4	1.000	0	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
76	JUN	oncoprotein	28	0.356	88.840	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
77	KIF11	protein found in more fusions	7	0.333	8.952	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
78	KLF10	suppressor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain AAA_33 (PF13671): AAA domain
79	KLF13	interactor	3	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
80	KLF15	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
81	KLF2	interactor	3	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
82	KLF8	interactor	6	0.800	0.872	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
83	MAFA	oncoprotein	1	0	0	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor GRP (PF07172, IPR010800): Glycine rich protein family Maf_N (PF08383, IPR013592): Maf N-terminal region
84	MAFB	oncoprotein	3	1.000	0	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region
85	MAGEA10	interactor	5	0.500	4.067	MAGE (PF01454, IPR002190): MAGE family SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
86	MAPK14	oncoprotein	15	0.407	29.553	Pkinase (PF00069, IPR000719): Protein kinase domain
87	MAPRE1	oncoprotein	5	0.833	0.500	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
88	MBIP	interactor	9	0.821	2.467	DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
89	MDM2	oncoprotein	41	0.209	352.306	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
90	MECOM	oncoprotein	8	0.536	3.859	SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
91	MED21	protein found in more fusions	9	0.750	2.779	Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
92	MED23	interactor	20	0.311	69.968	Med23 (PF11573, IPR021629): Mediator complex subunit 23
93	MEF2D	oncoprotein	6	0.800	0.822	DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
94	MYB	oncoprotein	7	0.762	1.530	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
95	MYC	oncoprotein	41	0.258	329.692	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
96	MYO1C	interactor	7	0.429	8.152	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
97	MYOD1	oncoprotein	12	0.564	7.450	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
98	MYSM1	interactor	3	0.667	0.667	SWIRM (PF04433, IPR007526): SWIRM domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
99	NCOA1	oncoprotein	21	0.405	50.333	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
100	NCOA3	oncoprotein	24	0.326	92.286	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
101	NCOA4	suppressor	3	1.000	0	ARA70 (PF12489, IPR022174): Nuclear coactivator
102	NFATC1	oncoprotein	14	0.352	34.066	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
103	NFE2	interactor	4	1.000	0	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase
104	NFE4	interactor	2	1.000	0	NA
105	NFYB	interactor	10	0.756	4.729	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
106	NFYC	interactor	9	0.583	9.274	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain
107	NKX3-1	suppressor	1	0	0	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
108	NPAS2	suppressor	7	0.905	0.800	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain
109	NR1H3	interactor	6	0.467	3.894	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
110	NR3C2	oncoprotein	4	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
111	NR4A1	suppressor	12	0.621	8.247	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
112	ONECUT1	suppressor	2	1.000	0	CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
113	PARP1	suppressor	33	0.266	181.769	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
114	PDK1	interactor	5	0.667	1.067	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
115	PGR	suppressor	10	0.528	7.235	Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
116	PLAGL1	suppressor	6	0.933	0.250	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
117	PNMA1	oncoprotein	2	1.000	0	PNMA (PF14893, IPR026523): PNMA
118	POLR1A	interactor	4	0.667	0.833	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
119	POLR2A	protein found in more fusions	22	0.333	72.704	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
120	PTEN	suppressor	11	0.400	15.007	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
121	PTF1A	interactor	3	0.667	1.000	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
122	RAB11A	oncoprotein	1	0	0	Ras (PF00071, IPR001806, SM00173): Ras family
123	RARA	oncoprotein	19	0.425	34.243	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
124	RB1	suppressor	29	0.323	115.636	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
125	RBM8A	interactor	3	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
126	RBPJ	interactor	9	0.306	16.401	BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain
127	RPS6KB1	interactor	8	0.476	6.086	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
128	RPS6KB2	interactor	7	0.429	7.717	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
129	RUNX2	suppressor	13	0.641	8.967	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
130	SAT2	interactor	4	1.000	0	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
131	SATB1	oncoprotein	9	0.472	9.802	CUT (PF02376, IPR003350, SM01109): CUT domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
132	SERBP1	interactor	7	0.533	3.014	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
133	SERTAD1	interactor	5	0.700	2.000	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif
134	SERTAD2	interactor	1	0	0	SERTA (PF06031, IPR009263): SERTA motif S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
135	SGF29	interactor	17	0.507	39.519	DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein
136	SIAH2	oncoprotein	7	0.400	4.869	Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
137	SIRT1	suppressor	30	0.254	162.350	DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
138	SMAD2	suppressor	22	0.419	51.375	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
139	SMAD3	oncoprotein	34	0.333	167.112	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
140	SMAD7	interactor	16	0.475	30.642	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
141	SMAD9	interactor	7	0.667	2.536	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
142	SMARCA2	suppressor	15	0.495	19.636	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
143	SMARCB1	suppressor	16	0.457	22.318	SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
144	SUPT3H	interactor	16	0.633	16.889	TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
145	TACC2	interactor	4	0.833	0.154	TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
146	TACC3	oncoprotein	3	0.667	1.000	TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
147	TADA1	interactor	14	0.714	10.239	SAGA-Tad1 (PF12767, IPR024738): Transcriptional regulator of RNA polII, SAGA, subunit
148	TADA2A	interactor	16	0.400	36.649	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
149	TADA3	interactor	25	0.363	116.420	GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF Ada3 (PF10198, IPR019340): Histone acetyltransferases subunit 3
150	TAF10	interactor	15	0.638	16.031	TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit
151	TAF12	interactor	12	0.636	14.264	TFIID_20kDa (PF03847, IPR003228): Transcription initiation factor TFIID subunit A
152	TAF15	oncoprotein	7	0.429	6.475	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
153	TAF1B	interactor	12	0.379	22.684	Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
154	TAF5L	interactor	12	0.667	10.340	TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
155	TAF6L	interactor	10	0.689	5.587	TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
156	TAF9	interactor	15	0.600	19.587	TFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
157	TAL1	oncoprotein	9	0.571	4.120	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
158	TCF3	suppressor	16	0.362	38.146	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
159	TMF1	interactor	2	1.000	0	Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) NHase_beta (PF02211, IPR024690): Nitrile hydratase beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain PilW (PF16074, IPR032092): Type IV Pilus-assembly protein W BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
160	TP53	suppressor	64	0.183	929.059	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
161	TP63	suppressor	10	0.639	4.594	Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
162	TP73	suppressor	18	0.485	35.656	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
163	TRRAP	interactor	20	0.316	65.758	BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal
164	TTF1	suppressor	3	0.667	0.333	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Spore_II_R (PF09551, IPR014202): Stage II sporulation protein R (spore_II_R) Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
165	TWIST1	oncoprotein	7	0.762	1.222	ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit PRR20 (PF15708, IPR031439): Proline-rich protein family 20 FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
166	UBE2D1	interactor	11	0.533	8.324	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
167	UBE2D3	interactor	4	0.667	0.400	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
168	UBTF	interactor	9	0.472	9.960	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HMG_box_2 (PF09011, IPR009071): HMG-box domain HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473) HMG_box_5 (PF14887, IPR029215): HMG (high mobility group) box 5
169	USF1	oncoprotein	8	0.619	2.167	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
170	VHL	suppressor	24	0.368	74.203	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
171	WDR5	interactor	22	0.294	113.091	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
172	XBP1	protein found in more fusions	3	1.000	0	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630)
173	XRCC6	oncoprotein	26	0.310	106.168	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
174	YEATS2	interactor	9	0.667	7.571	YEATS (PF03366, IPR005033): YEATS family
175	YY1	protein found in more fusions	16	0.571	13.874	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail

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