1 |
KAT2B | parental protein | 175 | 0.066 | 18317.722 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
2 |
ACLY | interactor | 1 | 0 | 0 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding |
3 |
ACTB | oncoprotein | 22 | 0.367 | 81.241 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTN1 | protein found in more fusions | 7 | 0.467 | 6.667 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
5 |
ACTN2 | protein found in more fusions | 3 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
6 |
AKT1 | oncoprotein | 26 | 0.333 | 92.335 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
7 |
AR | oncoprotein | 30 | 0.335 | 138.472 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
8 |
ARNTL | suppressor | 9 | 0.694 | 3.989 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain |
9 |
ATF4 | oncoprotein | 8 | 0.619 | 7.000 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
10 |
ATXN3 | interactor | 7 | 0.800 | 0.626 | Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
11 |
ATXN7L3 | interactor | 14 | 0.505 | 33.564 | SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) |
12 |
BCAS3 | oncoprotein | 5 | 0.500 | 1.971 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat BCAS3 (PF12490, IPR022175): Breast carcinoma amplified sequence 3 |
13 |
BRCA2 | suppressor | 9 | 0.528 | 9.269 | BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower |
14 |
BUB1B | oncoprotein | 7 | 0.533 | 2.175 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
15 |
CARM1 | oncoprotein | 19 | 0.380 | 44.466 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
16 |
CCNA2 | oncoprotein | 18 | 0.463 | 32.520 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
17 |
CCND1 | oncoprotein | 16 | 0.495 | 25.719 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
18 |
CCNT1 | oncoprotein | 5 | 0.833 | 0.333 | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor |
19 |
CDC25B | oncoprotein | 5 | 0.500 | 1.532 | M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain |
20 |
CDCA4 | interactor | 2 | 1.000 | 0 | SERTA (PF06031, IPR009263): SERTA motif |
21 |
CDK2 | suppressor | 47 | 0.201 | 527.392 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CDK8 | interactor | 19 | 0.464 | 31.538 | Pkinase (PF00069, IPR000719): Protein kinase domain |
23 |
CDKN1A | suppressor | 23 | 0.395 | 66.852 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
24 |
CDKN1B | suppressor | 10 | 0.467 | 9.890 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH |
25 |
CDT1 | oncoprotein | 7 | 0.667 | 2.767 | CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain |
26 |
CEBPB | oncoprotein | 19 | 0.444 | 33.721 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
27 |
CEP250 | interactor | 5 | 0.500 | 2.869 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
28 |
CHEK2 | suppressor | 10 | 0.500 | 8.658 | FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CLOCK | interactor | 7 | 0.905 | 0.505 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain |
30 |
CREBBP | suppressor | 74 | 0.155 | 1314.195 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
31 |
CTBP1 | protein found in more fusions | 21 | 0.358 | 66.719 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
32 |
CTBP2 | protein found in more fusions | 12 | 0.473 | 17.088 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
33 |
CTNNB1 | oncoprotein | 26 | 0.289 | 110.299 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
34 |
CUX1 | suppressor | 9 | 0.278 | 17.821 | Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein CUT (PF02376, IPR003350, SM01109): CUT domain DegS (PF05384, IPR008595): Sensor protein DegS DivIC (PF04977, IPR007060): Septum formation initiator DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Swi5 (PF07061, IPR010760): Swi5 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ApoO (PF09769, IPR019166): Apolipoprotein O Homeobox (PF00046, IPR001356, SM00389): Homeobox domain RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
35 |
DDX17 | protein found in more fusions | 13 | 0.470 | 16.410 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
DEK | oncoprotein | 11 | 0.564 | 12.458 | DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
37 |
DR1 | interactor | 8 | 0.786 | 4.667 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone SLED (PF12140, IPR021987): SLED domain |
38 |
E2F1 | suppressor | 15 | 0.571 | 11.501 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
39 |
EHMT2 | interactor | 16 | 0.286 | 41.795 | CDC45 (PF02724, IPR003874): CDC45-like protein Pre-SET (PF05033, IPR007728): Pre-SET motif Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family SET (PF00856, IPR001214, SM00317): SET domain SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus |
40 |
EP300 | oncoprotein | 94 | 0.134 | 2357.063 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
41 |
ERCC6 | oncoprotein | 12 | 0.348 | 20.286 | Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
42 |
ESRRA | oncoprotein | 4 | 0.667 | 0.422 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
43 |
ETS1 | oncoprotein | 12 | 0.712 | 6.721 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
44 |
ETV1 | oncoprotein | 6 | 0.867 | 0.295 | Ets (PF00178, IPR000418, SM00413): Ets-domain ETS_PEA3_N (PF04621, IPR006715): PEA3 subfamily ETS-domain transcription factor N terminal domain |
45 |
EZH2 | suppressor | 21 | 0.279 | 68.590 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
46 |
FLI1 | oncoprotein | 4 | 0.667 | 1.500 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
47 |
GLI1 | suppressor | 6 | 0.667 | 4.286 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
48 |
H2AFX | suppressor | 16 | 0.275 | 44.135 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
49 |
H3F3A | oncoprotein | 10 | 0.289 | 17.838 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
50 |
HDAC3 | suppressor | 30 | 0.296 | 126.629 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
51 |
HIF1A | suppressor | 24 | 0.413 | 65.350 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
52 |
HIST1H1A | interactor | 10 | 0.467 | 10.348 | Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
53 |
HIST1H1B | oncoprotein | 8 | 0.500 | 7.802 | Pneumo_att_G (PF05539, IPR008781): Pneumovirinae attachment membrane glycoprotein G Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
54 |
HIST1H2AB | interactor | 7 | 0.524 | 3.683 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
55 |
HIST1H2BB | interactor | 7 | 0.810 | 0.882 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
56 |
HIST1H3A | interactor | 26 | 0.250 | 135.965 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
57 |
HIST1H4A | interactor | 15 | 0.533 | 18.957 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
58 |
HIST2H2AC | interactor | 12 | 0.470 | 21.909 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
59 |
HIST2H2BE | interactor | 14 | 0.462 | 23.525 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
60 |
HIST2H3C | interactor | 7 | 0.429 | 4.812 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
61 |
HIST3H3 | interactor | 24 | 0.315 | 116.935 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
62 |
HIST4H4 | interactor | 11 | 0.400 | 13.612 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
63 |
HMGA1 | oncoprotein | 13 | 0.462 | 17.753 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
64 |
HMGN2 | interactor | 4 | 1.000 | 0 | HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17 |
65 |
HNF1A | oncoprotein | 8 | 0.667 | 1.503 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
66 |
HNRNPD | oncoprotein | 12 | 0.491 | 14.979 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
67 |
HNRNPU | interactor | 20 | 0.321 | 83.977 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
68 |
HOXA10 | interactor | 5 | 0.500 | 2.098 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266) |
69 |
HSD11B2 | interactor | 2 | 1.000 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase DUF1776 (PF08643, IPR013952): Fungal family of unknown function (DUF1776) |
70 |
HSPA4 | interactor | 13 | 0.538 | 8.771 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
71 |
HTT | protein found in more fusions | 10 | 0.556 | 7.314 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
72 |
ING1 | suppressor | 9 | 0.556 | 5.566 | PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
73 |
IRF1 | suppressor | 8 | 0.536 | 6.590 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor |
74 |
IRF2 | interactor | 4 | 1.000 | 0 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor |
75 |
IRF5 | suppressor | 4 | 1.000 | 0 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
76 |
JUN | oncoprotein | 28 | 0.356 | 88.840 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
77 |
KIF11 | protein found in more fusions | 7 | 0.333 | 8.952 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding |
78 |
KLF10 | suppressor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain AAA_33 (PF13671): AAA domain |
79 |
KLF13 | interactor | 3 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
80 |
KLF15 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
81 |
KLF2 | interactor | 3 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
82 |
KLF8 | interactor | 6 | 0.800 | 0.872 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
83 |
MAFA | oncoprotein | 1 | 0 | 0 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor GRP (PF07172, IPR010800): Glycine rich protein family Maf_N (PF08383, IPR013592): Maf N-terminal region |
84 |
MAFB | oncoprotein | 3 | 1.000 | 0 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region |
85 |
MAGEA10 | interactor | 5 | 0.500 | 4.067 | MAGE (PF01454, IPR002190): MAGE family SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
86 |
MAPK14 | oncoprotein | 15 | 0.407 | 29.553 | Pkinase (PF00069, IPR000719): Protein kinase domain |
87 |
MAPRE1 | oncoprotein | 5 | 0.833 | 0.500 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
88 |
MBIP | interactor | 9 | 0.821 | 2.467 | DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192) |
89 |
MDM2 | oncoprotein | 41 | 0.209 | 352.306 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
90 |
MECOM | oncoprotein | 8 | 0.536 | 3.859 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
91 |
MED21 | protein found in more fusions | 9 | 0.750 | 2.779 | Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex |
92 |
MED23 | interactor | 20 | 0.311 | 69.968 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
93 |
MEF2D | oncoprotein | 6 | 0.800 | 0.822 | DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
94 |
MYB | oncoprotein | 7 | 0.762 | 1.530 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
95 |
MYC | oncoprotein | 41 | 0.258 | 329.692 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
96 |
MYO1C | interactor | 7 | 0.429 | 8.152 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
97 |
MYOD1 | oncoprotein | 12 | 0.564 | 7.450 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
98 |
MYSM1 | interactor | 3 | 0.667 | 0.667 | SWIRM (PF04433, IPR007526): SWIRM domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
99 |
NCOA1 | oncoprotein | 21 | 0.405 | 50.333 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
100 |
NCOA3 | oncoprotein | 24 | 0.326 | 92.286 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
101 |
NCOA4 | suppressor | 3 | 1.000 | 0 | ARA70 (PF12489, IPR022174): Nuclear coactivator |
102 |
NFATC1 | oncoprotein | 14 | 0.352 | 34.066 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
103 |
NFE2 | interactor | 4 | 1.000 | 0 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase |
104 |
NFE4 | interactor | 2 | 1.000 | 0 | NA |
105 |
NFYB | interactor | 10 | 0.756 | 4.729 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone |
106 |
NFYC | interactor | 9 | 0.583 | 9.274 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain |
107 |
NKX3-1 | suppressor | 1 | 0 | 0 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
108 |
NPAS2 | suppressor | 7 | 0.905 | 0.800 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain |
109 |
NR1H3 | interactor | 6 | 0.467 | 3.894 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
110 |
NR3C2 | oncoprotein | 4 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
111 |
NR4A1 | suppressor | 12 | 0.621 | 8.247 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
112 |
ONECUT1 | suppressor | 2 | 1.000 | 0 | CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
113 |
PARP1 | suppressor | 33 | 0.266 | 181.769 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
114 |
PDK1 | interactor | 5 | 0.667 | 1.067 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase |
115 |
PGR | suppressor | 10 | 0.528 | 7.235 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
116 |
PLAGL1 | suppressor | 6 | 0.933 | 0.250 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
117 |
PNMA1 | oncoprotein | 2 | 1.000 | 0 | PNMA (PF14893, IPR026523): PNMA |
118 |
POLR1A | interactor | 4 | 0.667 | 0.833 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 |
119 |
POLR2A | protein found in more fusions | 22 | 0.333 | 72.704 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
120 |
PTEN | suppressor | 11 | 0.400 | 15.007 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
121 |
PTF1A | interactor | 3 | 0.667 | 1.000 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
122 |
RAB11A | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
123 |
RARA | oncoprotein | 19 | 0.425 | 34.243 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
124 |
RB1 | suppressor | 29 | 0.323 | 115.636 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
125 |
RBM8A | interactor | 3 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
126 |
RBPJ | interactor | 9 | 0.306 | 16.401 | BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain |
127 |
RPS6KB1 | interactor | 8 | 0.476 | 6.086 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
128 |
RPS6KB2 | interactor | 7 | 0.429 | 7.717 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
129 |
RUNX2 | suppressor | 13 | 0.641 | 8.967 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
130 |
SAT2 | interactor | 4 | 1.000 | 0 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
131 |
SATB1 | oncoprotein | 9 | 0.472 | 9.802 | CUT (PF02376, IPR003350, SM01109): CUT domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
132 |
SERBP1 | interactor | 7 | 0.533 | 3.014 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
133 |
SERTAD1 | interactor | 5 | 0.700 | 2.000 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif |
134 |
SERTAD2 | interactor | 1 | 0 | 0 | SERTA (PF06031, IPR009263): SERTA motif S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial |
135 |
SGF29 | interactor | 17 | 0.507 | 39.519 | DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein |
136 |
SIAH2 | oncoprotein | 7 | 0.400 | 4.869 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
137 |
SIRT1 | suppressor | 30 | 0.254 | 162.350 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
138 |
SMAD2 | suppressor | 22 | 0.419 | 51.375 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
139 |
SMAD3 | oncoprotein | 34 | 0.333 | 167.112 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
140 |
SMAD7 | interactor | 16 | 0.475 | 30.642 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
141 |
SMAD9 | interactor | 7 | 0.667 | 2.536 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
142 |
SMARCA2 | suppressor | 15 | 0.495 | 19.636 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
143 |
SMARCB1 | suppressor | 16 | 0.457 | 22.318 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
144 |
SUPT3H | interactor | 16 | 0.633 | 16.889 | TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093) |
145 |
TACC2 | interactor | 4 | 0.833 | 0.154 | TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) |
146 |
TACC3 | oncoprotein | 3 | 0.667 | 1.000 | TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
147 |
TADA1 | interactor | 14 | 0.714 | 10.239 | SAGA-Tad1 (PF12767, IPR024738): Transcriptional regulator of RNA polII, SAGA, subunit |
148 |
TADA2A | interactor | 16 | 0.400 | 36.649 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
149 |
TADA3 | interactor | 25 | 0.363 | 116.420 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF Ada3 (PF10198, IPR019340): Histone acetyltransferases subunit 3 |
150 |
TAF10 | interactor | 15 | 0.638 | 16.031 | TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit |
151 |
TAF12 | interactor | 12 | 0.636 | 14.264 | TFIID_20kDa (PF03847, IPR003228): Transcription initiation factor TFIID subunit A |
152 |
TAF15 | oncoprotein | 7 | 0.429 | 6.475 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
153 |
TAF1B | interactor | 12 | 0.379 | 22.684 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 |
154 |
TAF5L | interactor | 12 | 0.667 | 10.340 | TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
155 |
TAF6L | interactor | 10 | 0.689 | 5.587 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF) |
156 |
TAF9 | interactor | 15 | 0.600 | 19.587 | TFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
157 |
TAL1 | oncoprotein | 9 | 0.571 | 4.120 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
158 |
TCF3 | suppressor | 16 | 0.362 | 38.146 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
159 |
TMF1 | interactor | 2 | 1.000 | 0 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) NHase_beta (PF02211, IPR024690): Nitrile hydratase beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain PilW (PF16074, IPR032092): Type IV Pilus-assembly protein W BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
160 |
TP53 | suppressor | 64 | 0.183 | 929.059 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
161 |
TP63 | suppressor | 10 | 0.639 | 4.594 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
162 |
TP73 | suppressor | 18 | 0.485 | 35.656 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
163 |
TRRAP | interactor | 20 | 0.316 | 65.758 | BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal |
164 |
TTF1 | suppressor | 3 | 0.667 | 0.333 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Spore_II_R (PF09551, IPR014202): Stage II sporulation protein R (spore_II_R) Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519) |
165 |
TWIST1 | oncoprotein | 7 | 0.762 | 1.222 | ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit PRR20 (PF15708, IPR031439): Proline-rich protein family 20 FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
166 |
UBE2D1 | interactor | 11 | 0.533 | 8.324 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
167 |
UBE2D3 | interactor | 4 | 0.667 | 0.400 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
168 |
UBTF | interactor | 9 | 0.472 | 9.960 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HMG_box_2 (PF09011, IPR009071): HMG-box domain HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473) HMG_box_5 (PF14887, IPR029215): HMG (high mobility group) box 5 |
169 |
USF1 | oncoprotein | 8 | 0.619 | 2.167 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
170 |
VHL | suppressor | 24 | 0.368 | 74.203 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
171 |
WDR5 | interactor | 22 | 0.294 | 113.091 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
172 |
XBP1 | protein found in more fusions | 3 | 1.000 | 0 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630) |
173 |
XRCC6 | oncoprotein | 26 | 0.310 | 106.168 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
174 |
YEATS2 | interactor | 9 | 0.667 | 7.571 | YEATS (PF03366, IPR005033): YEATS family |
175 |
YY1 | protein found in more fusions | 16 | 0.571 | 13.874 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |