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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (66.67 %)
The number (and %) of affected PPIs6 (60.00 %)
The number of possible different fusions2
PPI diameter2
PPI radius1
The average degree of PPI2.667
Assortativity coefficient-0.4472
The network average Clustering coefficient0.550
The number (and %) of a zero Clustering coefficients2 (33.33 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)


List of the fusions

PPI for parental proteins: JAM3 All fusions
Proteins found in more fusions JAM3 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 JAM3parental protein60.30014.000Phage_Coat_B (PF05356, IPR008020): Phage Coat protein B
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
2 ITGAMinteractor100FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
3 JAM2interactor41.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
Ig_3 (PF13927): Immunoglobulin domain
DUF4307 (PF14155, IPR025443): Domain of unknown function (DUF4307)
4 PARD3interactor31.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
5 RHOUinteractor100Ras (PF00071, IPR001806, SM00173): Ras family
SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
6 TJP1interactor31.0000DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal

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