Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins JAK2 (from a repository: Thu Nov 10 14:59:26 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)92
The number (and %) of the onco-proteins52 (56.52 %)
The number (and %) of the tumor suppressors8 (8.70 %)
Total number of binary PPIs (saturation %)557 (13.31 %)
The number (and %) of affected PPIs92 (16.52 %)
The number of possible different fusions27
PPI diameter2
PPI radius1
The average degree of PPI11.174
Assortativity coefficient-0.2680
The network average Clustering coefficient0.557
The number (and %) of a zero Clustering coefficients2 (2.17 %)
The number (and %) of a zero Betweenness Centrality17 (18.48 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: JAK2 All fusions
Proteins found in more fusions RBMX (see 3 fusions); TRAF6 (see 1 fusions); PTPN11 (see 1 fusions); HSP90AA1 (see 2 fusions); PRMT5 (see 2 fusions); LYN (see 1 fusions); JAK2 (see 3 fusions); KPNB1 (see 2 fusions); HSP90AB1 (see 1 fusions); GRB2 (see 1 fusions); FYN (see 1 fusions); NAP1L1 (see 3 fusions); VHL (see 1 fusions); TNFRSF1A (see 2 fusions); ERBB3 (see 1 fusions); STAT3 (see 2 fusions); PRLR (see 1 fusions); EGFR (see 2 fusions); PIK3R1 (see 1 fusions); SHC1 (see 1 fusions); PTK2 (see 2 fusions); EZH2 (see 1 fusions); MAP3K5 (see 1 fusions); FGFR1 (see 1 fusions); DTX3L (see 2 fusions); STAT1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 JAK2parental protein920.1034982.293FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
2 AGTR1suppressor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
3 ALKoncoprotein130.50012.603MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
Gly_rich (PF12810): Glycine rich protein
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
4 ASB2interactor41.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
5 ASS1suppressor31.0000Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
6 BRCA1oncoprotein130.27334.434BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
7 CALM1interactor60.5335.333EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
8 CCR5interactor50.7001.0867tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
9 CDKN1Boncoprotein60.5333.217CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
10 CSF2RBinteractor80.4296.525fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Tissue_fac (PF01108, IPR003961): Tissue factor
11 CTLA4interactor60.4002.302V-set (PF07686, IPR013106): Immunoglobulin V-set domain
12 CXCR4interactor80.5008.0417tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
COX2_TM (PF02790, IPR011759): Cytochrome C oxidase subunit II, transmembrane domain
CXCR4_N (PF12109, IPR022726): CXCR4 Chemokine receptor N terminal
13 DNAJA3suppressor80.6077.650DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
14 DTX3Lprotein found in more fusions50.6672.000KH_1 (PF00013, IPR004088, SM00322): KH domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
15 EGFRoncoprotein380.266276.449Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
16 ELP2interactor40.8330.333WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
17 EMDinteractor51.0000LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
18 EPORoncoprotein140.41820.925EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
19 ERBB2oncoprotein220.48641.905Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
20 ERBB3oncoprotein170.56718.421Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
21 EZH2oncoprotein60.5003.833CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
22 FGFR1oncoprotein110.5119.088I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
23 FYNoncoprotein170.41731.034Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
24 GHRoncoprotein130.42410.394EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
GHBP (PF12772, IPR025871): Growth hormone receptor binding
25 GRB10oncoprotein100.4898.114BPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
26 GRB2oncoprotein360.299223.408SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
27 GTF2Iinteractor60.5334.633GTF2I (PF02946, IPR004212): GTF2I-like repeat
28 HES1oncoprotein41.0000Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
29 HES5interactor21.0000Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
30 HIST2H3Cinteractor40.8330.667Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
31 HIST3H3interactor50.7001.667Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
32 HSP90AA1oncoprotein290.288174.417HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
33 HSP90AB1oncoprotein100.7223.133HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
34 HSPA8oncoprotein150.41933.888HSP70 (PF00012, IPR013126): Hsp70 protein
35 HTR2Ainteractor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL
36 IFNGR1interactor40.8330.667IFNGR1 (PF07140, IPR021126): Interferon gamma receptor (IFNGR1)
Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
37 IFNGR2oncoprotein21.0000Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
38 IKBKGinteractor150.38528.420CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
39 IL12RB2interactor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
40 IL2RBoncoprotein90.4175.306IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
41 IL2RGoncoprotein40.8330.250fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
42 IL4Roncoprotein60.4673.208fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
43 IL5RAinteractor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Tissue_fac (PF01108, IPR003961): Tissue factor
44 IL6SToncoprotein110.6364.579fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
45 INSRinteractor160.38326.632fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
46 IRS1interactor150.52417.728CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
47 JAK3oncoprotein180.18383.778Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
48 KIToncoprotein140.39619.040ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
49 KPNB1protein found in more fusions50.6670.422Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
50 LYNoncoprotein180.36048.963Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
51 MAP3K5protein found in more fusions100.4727.070Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
52 NAP1L1protein found in more fusions31.0000NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
53 PIK3R1oncoprotein250.42861.683RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
54 PLCG1oncoprotein160.45828.584C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
55 PPIAinteractor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
56 PPP1CConcoprotein80.35713.075Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
57 PPP2R1Bsuppressor60.7000.900HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
58 PRLRoncoprotein80.4297.923EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
59 PRMT5protein found in more fusions70.5334.536PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
60 PTAFRinteractor30.6670.5007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
61 PTK2protein found in more fusions220.41466.077FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
62 PTK2Binteractor160.43828.379FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
63 PTPN1suppressor120.45520.271Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
64 PTPN11oncoprotein260.33786.041SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
65 PTPN12suppressor50.9000.286Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PTPlike_phytase (PF14566): Inositol hexakisphosphate
ER-remodelling (PF14755, IPR032786): Intracellular membrane remodeller
66 PTPN6oncoprotein170.36040.141SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
67 RAF1oncoprotein140.38531.520Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
68 RBMXoncoprotein50.5001.889RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
69 RCN1interactor100EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
70 SH2B1interactor80.6193.850Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PH (PF00169, IPR001849, SM00233): PH domain
Phe_ZIP (PF08916, IPR015012): Phenylalanine zipper
SH2 (PF00017, IPR000980, SM00252): SH2 domain
71 SH2B2oncoprotein80.7142.111PH (PF00169, IPR001849, SM00233): PH domain
Phe_ZIP (PF08916, IPR015012): Phenylalanine zipper
SH2 (PF00017, IPR000980, SM00252): SH2 domain
72 SHC1oncoprotein280.285138.056PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
73 SIRPAinteractor31.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
DUF4448 (PF14610, IPR028000): Protein of unknown function (DUF4448)
G6B (PF15096, IPR028070): G6B family
SIT (PF15330): SHP2-interacting transmembrane adaptor protein, SIT
74 SKP2oncoprotein60.5334.400LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
75 SLC2A1interactor30.6670.500Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
76 SOCS1oncoprotein180.39240.018SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
77 SOCS3suppressor190.23478.476SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
78 SRConcoprotein260.39377.358Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
79 STAMinteractor60.4677.333GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
80 STAM2interactor50.6002.533GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
81 STAT1suppressor180.29467.460SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
82 STAT3oncoprotein280.256169.338SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
83 STAT5Aoncoprotein150.30834.239SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
84 STAT5Boncoprotein170.32542.565SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
85 TECinteractor100.5119.154BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
86 TNFRSF1Aoncoprotein110.6006.145Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
87 TRAF6protein found in more fusions110.44414.194SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
88 TSHRoncoprotein21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
89 TUBinteractor21.0000Tub (PF01167, IPR000007): Tub family
Tub_N (PF16322, IPR005398): Tubby N-terminal
90 UBP1interactor100CP2 (PF04516, IPR007604): CP2 transcription factor
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
91 VAV1oncoprotein200.37465.403PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
92 VHLoncoprotein100.36115.206Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain

B a c k    t o    T o p ⇑