Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins IMMT (from a repository: Thu Nov 17 07:52:37 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)129
The number (and %) of the onco-proteins23 (17.83 %)
The number (and %) of the tumor suppressors12 (9.30 %)
Total number of binary PPIs (saturation %)687 (8.32 %)
The number (and %) of affected PPIs129 (18.78 %)
The number of possible different fusions21
PPI diameter2
PPI radius1
The average degree of PPI9.845
Assortativity coefficient-0.2713
The network average Clustering coefficient0.471
The number (and %) of a zero Clustering coefficients6 (4.65 %)
The number (and %) of a zero Betweenness Centrality20 (15.50 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: IMMT All fusions
: BU675384; BU685307; CB854254; BE159547;
Proteins found in more fusions SFPQ (see 6 fusions); CUL7 (see 2 fusions); ATXN1 (see 3 fusions); PINK1 (see 3 fusions); HNRNPD (see 1 fusions); NDUFS3 (see 1 fusions); NDEL1 (see 1 fusions); IMMT (see 4 fusions); TCF3 (see 3 fusions); EGFR (see 2 fusions); KDM1A (see 2 fusions); CHD3 (see 1 fusions); PARP1 (see 1 fusions); EZH2 (see 1 fusions); EP300 (see 1 fusions); CDC37 (see 2 fusions); ATP5A1 (see 1 fusions); TNNT1 (see 1 fusions); SUZ12 (see 2 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 IMMTparental protein1290.06212152.568Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
2 ABCE1interactor110.48910.018ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 ADCK1interactor200ABC1 (PF03109, IPR004147): ABC1 family
APH (PF01636, IPR002575): Phosphotransferase enzyme family
4 ADCK5interactor200ABC1 (PF03109, IPR004147): ABC1 family
APH (PF01636, IPR002575): Phosphotransferase enzyme family
5 ADRB2interactor130.36420.8457tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6 AKTIPinteractor21.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
7 ALBinteractor60.4676.400Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
8 APOOLinteractor70.5335.567ApoO (PF09769, IPR019166): Apolipoprotein O
9 ARMCX3oncoprotein100Arm_2 (PF04826, IPR006911): Armadillo-like
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
10 ASCC2interactor50.7001.333CUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
11 ATF2oncoprotein110.40016.267bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
12 ATP5A1protein found in more fusions230.281102.501ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
13 ATP5C1interactor240.286118.866ATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
14 ATXN1protein found in more fusions80.38112.333AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
15 BAG6interactor170.19276.180DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
16 BMI1oncoprotein130.22743.800zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
17 C10orf88interactor200DUF4506 (PF14958, IPR028043): Domain of unknown function (DUF4506)
18 C15orf48interactor100.5569.898B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
19 C19orf70interactor50.6003.167QIL1 (PF15884, IPR026769): Protein QIL1
20 C8orf33interactor31.0000DUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
21 CALM1interactor70.28612.250EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
22 CCDC113interactor21.0000DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
DUF2808 (PF10989, IPR021256): Protein of unknown function (DUF2808)
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Flavodoxin_5 (PF12724, IPR026816): Flavodoxin domain
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
23 CCDC8interactor160.32441.289Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
24 CCT5interactor110.23618.446Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
25 CD244interactor21.0000Receptor_2B4 (PF11465, IPR024303): Natural killer cell receptor 2B4
WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
26 CD81interactor90.5006.272Tetraspannin (PF00335, IPR018499): Tetraspanin family
27 CDC37protein found in more fusions110.33324.944CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
28 CDK9protein found in more fusions70.4003.590Pkinase (PF00069, IPR000719): Protein kinase domain
29 CHCHD10interactor50.6670.450CHCH (PF06747, IPR010625): CHCH domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
30 CHD3oncoprotein120.25533.500CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
31 CLN3interactor60.4006.733CLN3 (PF02487, IPR003492): CLN3 protein
32 CRY1interactor70.4002.344DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
33 CSTF2interactor70.4299.067RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
34 CUL7protein found in more fusions210.27471.106ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
35 DISC1interactor40.5003.000HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
36 DNAJC11suppressor80.39312.311DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395)
37 ECSITinteractor40.6670.500ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein
38 ECT2suppressor40.6671.067BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
39 EEF1A1suppressor230.160137.297GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
40 EGFRoncoprotein210.25896.591Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
41 EIF3Fsuppressor110.38224.830JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
42 EP300oncoprotein120.25526.772Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
43 EXOSC10interactor50.6001.075DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
HRDC (PF00570, IPR002121, SM00341): HRDC domain
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
44 EZH2suppressor90.32114.900CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
45 FAM173Ainteractor30.6670.667Methyltransf_23 (PF13489): Methyltransferase domain
46 FBXO6interactor210.25291.589FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
47 FEZ1interactor100.36120.333FEZ (PF07763, IPR011680): FEZ-like protein
DUF5102 (PF17104, IPR031355): Domain of unknown function (DUF5102)
48 GOLT1Binteractor130.50017.414Got1 (PF04178, IPR007305): Got1/Sft2-like family
49 HAP1interactor180.176106.167HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
50 HIVEP1suppressor21.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_7 (PF15269): Zinc-finger
51 HJURPinteractor100GAT (PF03127, IPR004152): GAT domain
Scm3 (PF10384, IPR018465): Centromere protein Scm3
HJURP_mid (PF12346, IPR021052): Holliday junction recognition protein-associated repeat
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
52 HMOX2interactor31.0000Heme_oxygenase (PF01126, IPR016053): Heme oxygenase
53 HNRNPDoncoprotein130.45520.349CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
54 HNRNPRinteractor160.30851.784RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
55 HP1BP3interactor80.3219.988RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SDA1 (PF05285, IPR007949): SDA1
YL1 (PF05764, IPR008895): YL1 nuclear protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
56 IRAK1interactor80.4298.967Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
57 ITGA4interactor180.29441.664FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
58 KDM1Aprotein found in more fusions140.23145.227Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
59 KIF22interactor30.6671.000Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
HHH_3 (PF12836): Helix-hairpin-helix motif
60 KPNA2interactor100.28915.990Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
61 LGR4interactor80.3338.9007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
62 LRIF1interactor130.30336.733LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
63 MDC1suppressor100.28920.400FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
64 MINOS1interactor40.6671.500DUF543 (PF04418, IPR007512): Domain of unknown function (DUF543)
65 MMGT1interactor70.7622.686MMgT (PF10270, IPR018937): Membrane magnesium transporter
66 MRPL44interactor40.5001.600dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
67 MRPL58interactor110.36415.784RF-1 (PF00472, IPR000352): RF-1 domain
68 MSMO1interactor31.0000FA_hydroxylase (PF04116, IPR006694): Fatty acid hydroxylase superfamily
DUF4886 (PF16227, IPR032616): Domain of unknown function (DUF4886)
69 MTX2interactor90.27822.200Tom37 (PF10568, IPR019564): Outer mitochondrial membrane transport complex protein
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
70 MYH9suppressor110.25528.999IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
71 MYO19interactor40.6670.667IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
72 NCSTNinteractor60.6672.194Nicastrin (PF05450, IPR008710): Nicastrin
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
73 NDEL1protein found in more fusions40.6671.000HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
74 NDUFA10interactor130.43630.102dNK (PF01712, IPR002624): Deoxynucleoside kinase
75 NDUFA12interactor130.56416.157NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12
76 NDUFA4interactor180.29460.136B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
77 NDUFA9interactor170.46327.752Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
78 NDUFB9interactor100.57814.747Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
79 NDUFS3protein found in more fusions240.277113.230Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
80 NEK2interactor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
81 NIPSNAP3Ainteractor21.0000NIPSNAP (PF07978, IPR012577): NIPSNAP
82 NOS3interactor40.6670.667FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
HTH_15 (PF12324, IPR024259): Helix-turn-helix domain of alkylmercury lyase
83 NTRK1oncoprotein400.144438.935I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
84 OBSL1interactor210.23785.110BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
85 OCIAD1interactor90.5005.219OCIA (PF07051, IPR009764): Ovarian carcinoma immunoreactive antigen (OCIA)
86 OTUB1interactor110.38222.367Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
87 PARP1suppressor140.32131.690BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
88 PDE4DIPoncoprotein70.33310.067ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1220 (PF06758, IPR010630, SM01148): Repeat of unknown function (DUF1220)
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
IncA (PF04156, IPR007285): IncA protein
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
FAM76 (PF16046, IPR032017): FAM76 protein
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
89 PFDN1interactor60.4005.867Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
90 PIAS4interactor60.4005.967CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
91 PINK1protein found in more fusions50.6672.000Pkinase (PF00069, IPR000719): Protein kinase domain
92 PLA2G15interactor21.0000LCAT (PF02450, IPR003386): Lecithin:cholesterol acyltransferase
93 PPOXinteractor40.5002.667Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
94 PRRC2Ainteractor80.35713.415BAT2_N (PF07001, IPR009738): BAT2 N-terminus
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
95 PTPMT1interactor60.7000.850DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
96 RAB5Concoprotein120.45515.769Ras (PF00071, IPR001806, SM00173): Ras family
97 RAB7Asuppressor80.5366.271Ras (PF00071, IPR001806, SM00173): Ras family
98 RER1interactor50.6002.889Rer1 (PF03248, IPR004932): Rer1 family
99 RNF126interactor50.6671.067Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zinc_ribbon_9 (PF14369): zinc-ribbon
100 SDHAF2oncoprotein21.0000Sdh5 (PF03937, IPR005631): Flavinator of succinate dehydrogenase
Peroxidase_2 (PF01328, IPR000028): Peroxidase, family 2
Reovirus_cap (PF00979, IPR000153): Reovirus outer capsid protein, Sigma 3
101 SENP3interactor40.8330.286Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
102 SFPQoncoprotein170.35038.707GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
103 SGPL1interactor80.6433.563Pyridoxal_deC (PF00282, IPR002129): Pyridoxal-dependent decarboxylase conserved domain
104 SIRT7interactor130.21833.952DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
105 SLC25A1interactor120.25825.556Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
106 SLC25A12interactor70.4296.325Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
107 SLC25A13interactor130.23136.172Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
108 SLC33A1interactor21.0000Acatn (PF13000, IPR024371): Acetyl-coenzyme A transporter 1
109 SMN1interactor120.25525.512SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
110 SNAPINinteractor21.0000Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
111 SRRTinteractor70.4295.419ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546)
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
112 STMN4interactor100Stathmin (PF00836, IPR000956): Stathmin family
Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
DUF3844 (PF12955, IPR024382): Domain of unknown function (DUF3844)
113 STX5interactor40.6671.167Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Syntaxin-18_N (PF10496, IPR019529): SNARE-complex protein Syntaxin-18 N-terminus
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
Syntaxin-5_N (PF11416, IPR021538): Syntaxin-5 N-terminal, Sly1p-binding domain
114 SUZ12suppressor50.6671.667DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
115 TAF1Dinteractor50.7002.067TAF1D (PF15333, IPR027976): TATA box-binding protein-associated factor 1D
116 TCF3suppressor80.3819.383CDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
117 TK1oncoprotein80.2868.756TK (PF00265, IPR001267, SM00203): Thymidine kinase
118 TNNT1protein found in more fusions40.6670.667Troponin (PF00992, IPR001978): Troponin
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
119 TOMM40interactor100.42216.275Porin_3 (PF01459, IPR027246): Eukaryotic porin
120 TRAF3IP1interactor40.5002.333MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
121 TUBGCP3interactor31.0000Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
122 TXNDC9interactor30.6670.500Thioredoxin (PF00085, IPR013766): Thioredoxin
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
123 UBQLN4interactor60.5003.389CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Arm_2 (PF04826, IPR006911): Armadillo-like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
124 UQCRQinteractor110.43616.911UcrQ (PF02939, IPR004205): UcrQ family
125 VAPAinteractor210.36764.207DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
126 VCAM1interactor180.31439.531C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
127 VDAC1interactor210.36768.092Porin_3 (PF01459, IPR027246): Eukaryotic porin
128 VDAC2interactor290.264188.126Porin_3 (PF01459, IPR027246): Eukaryotic porin
129 VDAC3interactor160.48328.621Porin_3 (PF01459, IPR027246): Eukaryotic porin

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ALBinteractorSerum_albumin (PF00273, IPR014760, SM00103): Serum albumin familyBE159547, BU685307, CB854254
2 IMMTparental proteinMitofilin (PF09731, IPR019133): Mitochondrial inner membrane proteinBE159547, BU685307, CB854254
3 NDUFB9interactorComplex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)BE159547, BU685307, CB854254
4 NIPSNAP3AinteractorNIPSNAP (PF07978, IPR012577): NIPSNAPBE159547, BU685307, CB854254
5 PFDN1interactorPrefoldin_2 (PF01920, IPR002777): Prefoldin subunitBE159547, BU685307, CB854254
6 RAB5ConcoproteinRas (PF00071, IPR001806, SM00173): Ras familyBE159547, BU685307, CB854254
7 RAB7AsuppressorRas (PF00071, IPR001806, SM00173): Ras familyBE159547, BU685307, CB854254
8 RER1interactorRer1 (PF03248, IPR004932): Rer1 familyBE159547, BU685307, CB854254
9 SLC25A1interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier proteinBE159547, BU685307, CB854254

B a c k    t o    T o p ⇑