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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)86
The number (and %) of the onco-proteins26 (30.23 %)
The number (and %) of the tumor suppressors16 (18.60 %)
Total number of binary PPIs (saturation %)395 (10.81 %)
The number (and %) of affected PPIs86 (21.77 %)
The number of possible different fusions24
PPI diameter2
PPI radius1
The average degree of PPI8.140
Assortativity coefficient-0.2103
The network average Clustering coefficient0.542
The number (and %) of a zero Clustering coefficients6 (6.98 %)
The number (and %) of a zero Betweenness Centrality19 (22.09 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HSF1 All fusions
: BE671029; AW016463;
Proteins found in more fusions CREBBP (see 6 fusions); PRKDC (see 3 fusions); GOPC (see 2 fusions); BAG3 (see 4 fusions); HSP90AA1 (see 2 fusions); MAPK1 (see 1 fusions); STUB1 (see 1 fusions); CTPS2 (see 1 fusions); HSPB1 (see 4 fusions); HSF1 (see 3 fusions); CHD3 (see 1 fusions); HSP90AB1 (see 1 fusions); FILIP1 (see 1 fusions); DHPS (see 1 fusions); NCOA6 (see 1 fusions); SMARCB1 (see 12 fusions); CDK6 (see 1 fusions); STRAP (see 2 fusions); HSBP1 (see 1 fusions); PCGF2 (see 1 fusions); STAT1 (see 1 fusions); NEDD4 (see 1 fusions); CBS (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HSF1parental protein860.0745453.445DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
2 AAMPinteractor41.0000PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
3 AARSinteractor90.38915.633DHHA1 (PF02272, IPR003156): DHHA1 domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
4 ANKMY2interactor90.36118.133zf-MYND (PF01753, IPR002893): MYND finger
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
zf-C6H2 (PF15801, IPR031615): zf-MYND-like zinc finger, mRNA-binding
5 ARPC1Binteractor100.44419.067WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
6 BAG3oncoprotein110.6899.038BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
7 BTF3L4interactor60.6003.067NAC (PF01849, IPR002715): NAC domain
8 BTRConcoprotein70.4007.333WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
9 CALUinteractor90.38916.700EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
10 CBSprotein found in more fusions80.42910.833CBS (PF00571, IPR000644, SM00116): CBS domain
DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414)
PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme
11 CDC20oncoprotein120.32730.333WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
12 CDK6suppressor41.0000Pkinase (PF00069, IPR000719): Protein kinase domain
13 CEBPBoncoprotein90.5718.400RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
14 CHD3oncoprotein70.8670.536CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
15 CHST10suppressor100Sulfotransfer_2 (PF03567, IPR005331): Sulfotransferase family
SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
16 CREBBPsuppressor160.38149.052Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
17 CTPS2protein found in more fusions70.6004.833CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
18 DAXXoncoprotein140.35937.352Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
19 DENND5Binteractor100dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
RUN (PF02759, IPR004012, SM00593): RUN domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
20 DHPSprotein found in more fusions90.46410.633DS (PF01916, IPR002773): Deoxyhypusine synthase
21 DNAJB1suppressor70.7142.571DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
22 DR1interactor80.53610.133CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
SLED (PF12140, IPR021987): SLED domain
23 DTD1interactor21.0000Tyr_Deacylase (PF02580, IPR003732): D-Tyr-tRNA(Tyr) deacylase
EST1 (PF10374, IPR019458): Telomerase activating protein Est1
24 ENO2interactor21.0000Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
25 FBXW7suppressor50.6671.667Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
26 FILIP1protein found in more fusions200BAAT_C (PF08840, IPR014940): BAAT / Acyl-CoA thioester hydrolase C terminal
DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
Laminin_II (PF06009, IPR010307): Laminin Domain II
PspB (PF06667, IPR009554): Phage shock protein B
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
27 FKBP4interactor70.7144.952FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
28 FKBP5interactor80.46412.452FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
NuDC (PF16273, IPR032572): Nuclear distribution C domain
29 GON7interactor50.6003.333DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
30 GOPConcoprotein70.5335.400DUF903 (PF06004, IPR010305): Bacterial protein of unknown function (DUF903)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF3209 (PF11483, IPR021577): Protein of unknown function (DUF3209)
31 GTF2Binteractor40.8330.500Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
32 HDAC1suppressor200.29291.652FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
33 HDAC2suppressor120.50915.850Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
34 HSBP1protein found in more fusions31.0000HSBP1 (PF06825, IPR009643): Heat shock factor binding protein 1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
35 HSF2interactor50.5004.400HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
36 HSF4interactor50.4005.500Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
37 HSP90AA1oncoprotein210.31697.743HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
38 HSP90AB1oncoprotein170.45837.076HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
39 HSPA1Ainteractor90.6945.252HSP70 (PF00012, IPR013126): Hsp70 protein
40 HSPA4interactor180.30779.583Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
41 HSPA4Linteractor60.5335.500HSP70 (PF00012, IPR013126): Hsp70 protein
42 HSPA8oncoprotein160.43342.357HSP70 (PF00012, IPR013126): Hsp70 protein
43 HSPB1oncoprotein170.35058.586HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
44 HSPB2interactor41.0000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
45 HSPBP1interactor90.36120.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like
HEAT_EZ (PF13513): HEAT-like repeat
46 IPO11interactor90.52810.700DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
HEAT_2 (PF13646): HEAT repeats
47 KIAA0101interactor100PAF (PF15715, IPR031444): PCNA-associated factor
48 KPNA3interactor70.4767.983Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
49 KPNA4interactor50.8000.900Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
50 LRSAM1interactor120.32729.300Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
51 LURAP1Linteractor100Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
LURAP (PF14854): Leucine rich adaptor protein
52 MAD2L1oncoprotein41.0000HORMA (PF02301, IPR003511): HORMA domain
53 MAPK1oncoprotein60.5004.333Pkinase (PF00069, IPR000719): Protein kinase domain
54 MAPK8oncoprotein60.5002.417DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
55 MAPKAPK2oncoprotein40.6671.000Pkinase (PF00069, IPR000719): Protein kinase domain
56 MTA1oncoprotein80.6794.269BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
57 MTMR2interactor51.0000GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
58 MYH13interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
59 NCOA6oncoprotein70.6673.000DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
60 NEDD4suppressor40.6670.667Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
61 NME2interactor31.0000NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
62 PCGF2suppressor41.0000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
63 PLIN3interactor140.33340.667Perilipin (PF03036, IPR004279): Perilipin family
64 PLK1suppressor50.4003.900Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
65 PPIDinteractor90.50011.900Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
66 PRKDCprotein found in more fusions120.38225.900FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
67 PTGES3interactor110.48915.619CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
68 RALBP1interactor30.6670.667DDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
69 RPRD1Ainteractor60.5335.567CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
GlutR_N (PF05201, IPR015895): Glutamyl-tRNAGlu reductase, N-terminal domain
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
70 SIRT1suppressor110.40018.252DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
71 SMARCA4suppressor90.52811.667DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
72 SMARCB1suppressor70.9330.333SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
73 SRP9interactor80.46410.200SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
74 STAT1suppressor90.46411.733SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
75 STRAPprotein found in more fusions31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
76 STUB1suppressor140.53820.305U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
77 SURF2interactor60.5336.067SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
78 SYMPKinteractor21.0000HEAT (PF02985, IPR000357): HEAT repeat
DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453)
Symplekin_C (PF12295, IPR022075): Symplekin tight junction protein C terminal
Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion
79 TAF9interactor60.4007.833TFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
80 TBPinteractor90.46412.233TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
81 TPRKBinteractor70.5248.400CGI-121 (PF08617, IPR013926): Kinase binding protein CGI-121
82 UBE2Iinteractor190.229100.002UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
83 UBE3Aoncoprotein110.40021.633HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
84 XRCC5suppressor80.5715.586Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
85 XRCC6oncoprotein80.4768.067Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
86 ZPR1interactor31.0000zf-ZPR1 (PF03367, IPR004457, SM00709): ZPR1 zinc-finger domain

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