1 |
HNRNPL | parental protein | 107 | 0.230 | 3241.922 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
2 |
ABCC1 | oncoprotein | 7 | 0.600 | 3.709 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304) DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) |
3 |
ACTR3 | interactor | 8 | 0.536 | 1.219 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
APEX1 | interactor | 10 | 0.556 | 5.216 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family |
5 |
ATP6V1F | interactor | 4 | 0.500 | 2.333 | ATP-synt_F (PF01990, IPR008218): ATP synthase (F/14-kDa) subunit |
6 |
CAND1 | interactor | 43 | 0.573 | 70.227 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
7 |
CCDC8 | interactor | 32 | 0.484 | 35.129 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
8 |
COPS5 | protein found in more fusions | 44 | 0.529 | 69.793 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
9 |
CRY1 | interactor | 17 | 0.542 | 5.154 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
10 |
CSE1L | oncoprotein | 14 | 0.451 | 6.275 | CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
11 |
CSNK2A1 | oncoprotein | 26 | 0.443 | 47.195 | Pkinase (PF00069, IPR000719): Protein kinase domain |
12 |
CUL1 | oncoprotein | 43 | 0.599 | 50.041 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
13 |
CUL3 | protein found in more fusions | 46 | 0.497 | 91.987 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
14 |
CUL7 | protein found in more fusions | 47 | 0.430 | 102.307 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
15 |
DAB2 | oncoprotein | 2 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
16 |
DDX17 | protein found in more fusions | 47 | 0.476 | 103.962 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
17 |
DHX15 | interactor | 31 | 0.548 | 27.982 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
18 |
DOCK4 | interactor | 4 | 0.833 | 0.133 | DHR-2 (PF06920, IPR010703): Dock homology region 2 SH3_2 (PF07653, IPR011511): Variant SH3 domain DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins DOCK_N (PF16172, IPR032376): DOCK N-terminus |
19 |
DPH5 | interactor | 2 | 1.000 | 0 | TP_methylase (PF00590, IPR000878): Tetrapyrrole (Corrin/Porphyrin) Methylases |
20 |
DYNC1H1 | interactor | 18 | 0.510 | 7.210 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
21 |
EED | suppressor | 36 | 0.523 | 41.047 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
22 |
EEF1A1 | oncoprotein | 42 | 0.406 | 120.263 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
23 |
EEF2 | interactor | 27 | 0.530 | 30.373 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
24 |
EIF2B1 | interactor | 6 | 1.000 | 0 | IF-2B (PF01008, IPR000649): Initiation factor 2 subunit family |
25 |
EIF4A3 | interactor | 34 | 0.572 | 48.439 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
26 |
EIF4H | interactor | 12 | 0.682 | 2.614 | eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
27 |
ELAVL1 | oncoprotein | 41 | 0.441 | 118.308 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
28 |
FBXO6 | interactor | 27 | 0.456 | 31.014 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
29 |
FGFR3 | oncoprotein | 2 | 0 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
30 |
FN1 | oncoprotein | 52 | 0.354 | 233.662 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
31 |
FOXE1 | oncoprotein | 2 | 1.000 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
32 |
FUS | oncoprotein | 47 | 0.501 | 122.748 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
33 |
GCN1 | interactor | 13 | 0.436 | 3.825 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
34 |
HDAC5 | protein found in more fusions | 29 | 0.434 | 33.247 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
35 |
HIST1H3E | interactor | 9 | 0.722 | 0.990 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
36 |
HIST3H3 | interactor | 14 | 0.714 | 3.378 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
37 |
HMG20B | interactor | 1 | 0 | 0 | IncA (PF04156, IPR007285): IncA protein NEMP (PF10225, IPR019358): NEMP family HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496) |
38 |
HMGA1 | oncoprotein | 14 | 0.571 | 16.976 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
39 |
HNRNPA0 | interactor | 37 | 0.598 | 49.501 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
40 |
HNRNPA1 | interactor | 63 | 0.471 | 221.065 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
41 |
HNRNPA2B1 | oncoprotein | 44 | 0.485 | 98.354 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
42 |
HNRNPA3 | oncoprotein | 46 | 0.536 | 86.644 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
43 |
HNRNPD | oncoprotein | 48 | 0.476 | 146.509 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
44 |
HNRNPDL | interactor | 45 | 0.470 | 137.799 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
45 |
HNRNPH1 | oncoprotein | 51 | 0.505 | 115.018 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
46 |
HNRNPK | oncoprotein | 60 | 0.430 | 244.041 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
47 |
HNRNPM | interactor | 39 | 0.494 | 66.102 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
48 |
HNRNPR | interactor | 50 | 0.463 | 155.030 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
49 |
HNRNPU | interactor | 54 | 0.452 | 181.574 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
50 |
HSPA5 | oncoprotein | 42 | 0.488 | 113.930 | HSP70 (PF00012, IPR013126): Hsp70 protein |
51 |
HSPA9 | oncoprotein | 28 | 0.497 | 35.297 | HSP70 (PF00012, IPR013126): Hsp70 protein |
52 |
HSPBP1 | interactor | 5 | 0.700 | 1.087 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like HEAT_EZ (PF13513): HEAT-like repeat |
53 |
IFIT2 | interactor | 9 | 0.722 | 1.621 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein |
54 |
IFIT3 | interactor | 11 | 0.756 | 1.840 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
55 |
IL7R | interactor | 16 | 0.583 | 4.996 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
56 |
ILF3 | oncoprotein | 48 | 0.380 | 182.124 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
57 |
ISG15 | suppressor | 15 | 0.438 | 17.748 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
58 |
ITCH | interactor | 10 | 0.556 | 4.100 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
59 |
ITGA4 | interactor | 44 | 0.421 | 115.487 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
60 |
IVNS1ABP | protein found in more fusions | 13 | 0.727 | 1.482 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
61 |
KHDRBS2 | interactor | 13 | 0.742 | 1.102 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
62 |
LGALS1 | interactor | 9 | 0.583 | 3.328 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin |
63 |
LPP | oncoprotein | 8 | 0.536 | 5.050 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
64 |
LSM14A | interactor | 9 | 0.750 | 0.911 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FDF (PF09532, IPR019050, SM01199): FDF domain GRP (PF07172, IPR010800): Glycine rich protein family LSM14 (PF12701, IPR025609): Scd6-like Sm domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
65 |
MAGOH | interactor | 17 | 0.537 | 13.433 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
66 |
MATR3 | interactor | 39 | 0.605 | 44.725 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
67 |
MBNL1 | interactor | 8 | 0.893 | 0.169 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 (PF15663): Zinc-finger containing family |
68 |
MCM2 | oncoprotein | 53 | 0.422 | 186.892 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
69 |
MPV17 | interactor | 4 | 0.500 | 1.792 | Mpv17_PMP22 (PF04117, IPR007248): Mpv17 / PMP22 family |
70 |
MRPL41 | interactor | 5 | 0.600 | 0.425 | MRP-L27 (PF09809, IPR019189): Mitochondrial ribosomal protein L27 |
71 |
NAA50 | interactor | 5 | 0.700 | 0.530 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
72 |
NARS | interactor | 6 | 0.800 | 0.313 | tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain |
73 |
NEDD4 | suppressor | 8 | 0.857 | 0.571 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
74 |
NPLOC4 | interactor | 11 | 0.618 | 5.412 | NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4 |
75 |
NTRK1 | oncoprotein | 60 | 0.345 | 402.399 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
76 |
OBSL1 | interactor | 45 | 0.445 | 83.328 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
77 |
PCBP2 | protein found in more fusions | 28 | 0.513 | 33.592 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
78 |
PDHA1 | interactor | 7 | 0.857 | 0.195 | E1_dh (PF00676, IPR001017): Dehydrogenase E1 component |
79 |
PLEC | oncoprotein | 13 | 0.474 | 4.412 | CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FUSC (PF04632, IPR006726): Fusaric acid resistance protein family RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 S10_plectin (PF03501, IPR005326): Plectin/S10 domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229) Plectin (PF00681, IPR001101, SM00250): Plectin repeat YlqD (PF11068, IPR021297): YlqD protein Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
80 |
PTBP1 | oncoprotein | 48 | 0.502 | 103.468 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
81 |
PUF60 | protein found in more fusions | 22 | 0.595 | 28.488 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
82 |
RNF2 | interactor | 29 | 0.389 | 54.336 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
83 |
RPA1 | suppressor | 38 | 0.635 | 37.701 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
84 |
RPA2 | oncoprotein | 33 | 0.665 | 21.761 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
85 |
RPA3 | interactor | 33 | 0.663 | 22.479 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
86 |
SCARNA22 | interactor | 16 | 0.742 | 2.223 | NA |
87 |
SF1 | protein found in more fusions | 21 | 0.495 | 20.891 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
88 |
SFPQ | oncoprotein | 39 | 0.484 | 98.190 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
89 |
SMARCAD1 | interactor | 14 | 0.725 | 2.312 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
90 |
SNU13 | interactor | 16 | 0.676 | 8.345 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
91 |
SRRM2 | interactor | 31 | 0.572 | 35.472 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
92 |
SYNCRIP | interactor | 48 | 0.465 | 136.722 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
93 |
TOP1 | oncoprotein | 29 | 0.539 | 33.872 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
94 |
TOPORS | oncoprotein | 9 | 0.667 | 1.175 | Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
95 |
TP53 | oncoprotein | 34 | 0.398 | 96.081 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
96 |
TP63 | suppressor | 11 | 0.578 | 3.869 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
97 |
TRIM68 | interactor | 1 | 0 | 0 | GAGA (PF09237, IPR015318): GAGA factor SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
98 |
TUFM | interactor | 18 | 0.484 | 7.499 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
99 |
U2AF2 | protein found in more fusions | 48 | 0.515 | 90.696 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
100 |
UBC | protein found in more fusions | 47 | 0.485 | 135.150 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
101 |
UBL4A | interactor | 19 | 0.456 | 12.035 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
102 |
UNK | interactor | 20 | 0.300 | 38.712 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
103 |
VCAM1 | interactor | 39 | 0.395 | 77.700 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
104 |
VEGFA | oncoprotein | 5 | 0.500 | 0.209 | PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 VEGF_C (PF14554, IPR027928): VEGF heparin-binding domain |
105 |
VHL | oncoprotein | 24 | 0.656 | 15.683 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
106 |
YWHAE | oncoprotein | 24 | 0.438 | 20.866 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
107 |
YWHAZ | protein found in more fusions | 22 | 0.490 | 11.459 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |