Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins HNRNPD (from a repository: Fri Nov 11 23:09:06 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 269 The number (and %) of the onco-proteins 82 (30.48 %) The number (and %) of the tumor suppressors 29 (10.78 %) Total number of binary PPIs (saturation %) 3081 (8.55 %) The number (and %) of affected PPIs 269 (8.73 %) The number of possible different fusions 45 PPI diameter 2 PPI radius 1 The average degree of PPI 22.193 Assortativity coefficient -0.2567 The network average Clustering coefficient 0.505 The number (and %) of a zero Clustering coefficients 18 (6.69 %) The number (and %) of a zero Betweenness Centrality 51 (18.96 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: HNRNPD	All fusions
Proteins found in more fusions	U2AF2 (see 2 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); VHL (see 1 fusions); TNFRSF1A (see 2 fusions); EWSR1 (see 2 fusions); HDAC5 (see 1 fusions); MSH2 (see 1 fusions); RPA1 (see 1 fusions); SNW1 (see 1 fusions); PTBP1 (see 1 fusions); HSPB1/OBSL1 (see 1 fusions); CUL4A (see 4 fusions); TNF (see 1 fusions); SFPQ (see 6 fusions); COPS5/HNRNPH3 (see 3 fusions); HNRNPD (see 1 fusions); HSPB1 (see 3 fusions); USP11 (see 4 fusions); NCL (see 3 fusions); RBMX (see 3 fusions); STAU1 (see 2 fusions); PEX10 (see 1 fusions); HNRNPH3 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); MRPL12 (see 1 fusions); IVNS1ABP (see 2 fusions); MYC (see 1 fusions); KAT2B (see 1 fusions); ACTB (see 3 fusions); IMMT (see 4 fusions); COPS5 (see 1 fusions); MTOR (see 1 fusions); SREK1 (see 4 fusions); FUS/PKM (see 1 fusions); VEGFA (see 1 fusions); PABPC1 (see 2 fusions); HNRNPL (see 2 fusions); PCBP2 (see 3 fusions); MCM2 (see 1 fusions); HNRNPC (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	HNRNPD	parental protein	269	0.076	42696.344	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
2	ABCA7	interactor	2	1.000	0	ABC_tran (PF00005, IPR003439): ABC transporter ABC2_membrane_3 (PF12698): ABC-2 family transporter protein AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 (PF13732, IPR025302): Domain of unknown function (DUF4162)
3	ABCC10	interactor	1	0	0	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
4	ACSL4	interactor	2	1.000	0	AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
5	ACTB	oncoprotein	42	0.332	114.630	Actin (PF00022, IPR004000, SM00268): Actin
6	ADGRE5	oncoprotein	1	0	0	7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family) EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_MSP1_1 (PF12946, IPR024730): MSP1 EGF domain 1
7	AHNAK	suppressor	23	0.537	12.341	DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37
8	ARF4	interactor	9	0.500	4.941	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
9	ARHGAP32	oncoprotein	7	0.524	2.104	PX (PF00787, IPR001683, SM00312): PX domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RPEL (PF02755, IPR004018, SM00707): RPEL repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain
10	ARRB2	interactor	38	0.329	122.505	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
11	ASB2	interactor	13	0.652	7.463	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
12	AURKA	oncoprotein	23	0.364	54.786	Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding
13	B3GAT3	interactor	3	1.000	0	Glyco_transf_43 (PF03360, IPR005027): Glycosyltransferase family 43
14	BAG6	interactor	37	0.098	444.413	DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1
15	BANF1	interactor	9	0.286	5.874	BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
16	BCL2	oncoprotein	6	0.700	0.694	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
17	BET1L	interactor	1	0	0	CDV3 (PF15359, IPR026806): Carnitine deficiency-associated protein 3
18	BLMH	interactor	8	0.524	2.705	Peptidase_C1_2 (PF03051, IPR004134): Peptidase C1-like family
19	BRCA1	suppressor	35	0.232	210.195	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
20	BTRC	oncoprotein	24	0.368	49.500	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
21	C1QBP	interactor	26	0.483	26.472	MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
22	C2CD5	oncoprotein	6	0.600	2.273	C2 (PF00168, IPR000008, SM00239): C2 domain YbjQ_1 (PF01906, IPR002765): Putative heavy-metal-binding
23	C2orf49	interactor	3	1.000	0	Ashwin (PF15323, IPR024887): Developmental protein
24	CAND1	interactor	75	0.363	384.619	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
25	CAPN1	interactor	13	0.564	8.897	Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
26	CD4	suppressor	11	0.467	3.853	ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
27	CD81	interactor	27	0.360	51.864	Tetraspannin (PF00335, IPR018499): Tetraspanin family
28	CDK2	suppressor	55	0.307	296.869	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
29	CDK9	protein found in more fusions	23	0.489	29.160	Pkinase (PF00069, IPR000719): Protein kinase domain
30	CETN2	interactor	2	1.000	0	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
31	CHEK1	suppressor	12	0.409	14.148	Pkinase (PF00069, IPR000719): Protein kinase domain
32	CHMP5	interactor	5	0.667	0.733	Snf7 (PF03357, IPR005024): Snf7
33	CINP	interactor	1	0	0	Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
34	COG2	interactor	3	1.000	0	COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Syntaxin_2 (PF14523): Syntaxin-like protein
35	COG7	interactor	5	0.700	2.000	COG7 (PF10191, IPR019335): Golgi complex component 7 (COG7)
36	COL18A1	oncoprotein	2	1.000	0	Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF959 (PF06121, IPR010363): Domain of Unknown Function (DUF959) Endostatin (PF06482, IPR010515): Collagenase NC10 and Endostatin Fz (PF01392, IPR020067, SM00063): Fz domain Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
37	COPS5	protein found in more fusions	77	0.338	574.518	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
38	COPS6	interactor	40	0.511	96.824	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
39	CTSB	oncoprotein	3	0.667	1.000	Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease Propeptide_C1 (PF08127, IPR012599): Peptidase family C1 propeptide
40	CUL1	suppressor	81	0.336	545.704	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
41	CUL2	suppressor	55	0.411	188.256	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
42	CUL3	protein found in more fusions	90	0.286	874.157	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
43	CUL4A	protein found in more fusions	35	0.512	81.058	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
44	CUL4B	oncoprotein	48	0.485	106.270	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
45	CUL5	suppressor	56	0.457	152.951	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
46	CUL7	protein found in more fusions	69	0.248	431.704	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
47	CUTA	interactor	2	1.000	0	CutA1 (PF03091, IPR004323): CutA1 divalent ion tolerance protein
48	DCUN1D1	interactor	37	0.632	39.359	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
49	DDX1	oncoprotein	42	0.437	110.248	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
50	DDX51	interactor	1	0	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3330 (PF11809, IPR021767): Domain of unknown function (DUF3330) FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
51	DENR	oncoprotein	3	0.667	0.057	SUI1 (PF01253, IPR001950): Translation initiation factor SUI1
52	DGCR2	interactor	1	0	0	UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
53	DHX30	interactor	19	0.585	7.319	Bombolitin (PF08096, IPR012534): Bombolitin family DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
54	DICER1	suppressor	7	0.600	0.930	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
55	DKC1	oncoprotein	18	0.301	31.197	DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain PUA (PF01472, IPR002478, SM00359): PUA domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
56	DNAJC7	interactor	13	0.500	10.397	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
57	DNM2	interactor	11	0.436	11.679	Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
58	DYNC1H1	interactor	25	0.497	23.106	AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5
59	DYSF	interactor	1	0	0	C2 (PF00168, IPR000008, SM00239): C2 domain FerA (PF08165, IPR012560): FerA (NUC095) domain FerB (PF08150, IPR012561): FerB (NUC096) domain FerI (PF08151, IPR012968): FerI (NUC094) domain Pex24p (PF06398, IPR010482): Integral peroxisomal membrane peroxin Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
60	EED	suppressor	49	0.313	189.221	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
61	EEF2	interactor	36	0.502	59.425	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
62	EIF3K	interactor	10	0.511	8.670	CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
63	EIF4G1	oncoprotein	13	0.551	2.665	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) MA3 (PF02847, IPR003891, SM00544): MA3 domain MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
64	EIF6	interactor	14	0.560	10.902	eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family
65	ENO1	oncoprotein	35	0.393	87.941	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
66	ERG	oncoprotein	18	0.418	10.047	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
67	ERI1	interactor	1	0	0	RNase_T (PF00929, IPR013520): Exonuclease SAP (PF02037, IPR003034, SM00513): SAP domain
68	ESPL1	interactor	5	0.600	0.531	Peptidase_C50 (PF03568, IPR005314): Peptidase family C50
69	ESR1	suppressor	55	0.308	256.185	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
70	ETFA	interactor	8	0.393	8.738	ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
71	EWSR1	oncoprotein	51	0.374	230.813	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
72	EXOSC4	interactor	9	0.536	7.021	RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
73	FAM120A	interactor	12	0.788	1.239	TPR_15 (PF13429): Tetratricopeptide repeat
74	FANCD2	oncoprotein	8	0.500	6.974	FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
75	FBXL15	interactor	4	0.667	0.217	LRV (PF01816, IPR004830): Leucine rich repeat variant F-box (PF00646, IPR001810, SM00256): F-box domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
76	FBXW11	interactor	39	0.334	194.397	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
77	FLNA	suppressor	35	0.264	136.484	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
78	FN1	oncoprotein	76	0.239	632.552	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
79	FNDC3A	interactor	3	0.667	0.087	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Reeler (PF02014, IPR002861): Reeler domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
80	FUBP3	interactor	20	0.484	15.793	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain
81	FUS	suppressor	70	0.361	503.946	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
82	GCFC2	interactor	2	1.000	0	DUF1676 (PF07898, IPR012464): Protein of unknown function (DUF1676) GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
83	GOLGA4	interactor	2	1.000	0	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DivIC (PF04977, IPR007060): Septum formation initiator DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Fez1 (PF06818): Fez1 FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) GRIP (PF01465, IPR000237, SM00755): GRIP domain Mnd1 (PF03962, IPR005647): Mnd1 family Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SlyX (PF04102, IPR007236): SlyX Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 XhlA (PF10779, IPR019715): Haemolysin XhlA YlqD (PF11068, IPR021297): YlqD protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_13 (PF16925, IPR011075): Bacterial transcriptional repressor C-terminal
84	GPBP1	interactor	1	0	0	ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL Vasculin (PF15337, IPR028128): Vascular protein family Vasculin-like 1
85	GPN1	interactor	9	0.667	1.744	ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein NB-ARC (PF00931, IPR002182): NB-ARC domain
86	GPRIN1	interactor	2	1.000	0	GRIN_C (PF15235, IPR032745): G protein-regulated inducer of neurite outgrowth C-terminus
87	GRB2	oncoprotein	32	0.368	131.562	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
88	GTF2IRD1	interactor	6	0.400	3.352	GTF2I (PF02946, IPR004212): GTF2I-like repeat SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
89	GTF3C3	interactor	5	0.600	0.593	BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat
90	GTSE1	interactor	4	0.667	1.667	GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
91	GUK1	interactor	3	0.667	0.074	Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
92	H2AFX	suppressor	30	0.287	98.915	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
93	HBZ	interactor	5	0.600	0.431	Globin (PF00042, IPR000971): Globin
94	HDAC1	suppressor	20	0.368	40.199	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
95	HDAC5	protein found in more fusions	36	0.339	93.811	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
96	HEATR3	interactor	2	1.000	0	HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
97	HEXA	interactor	4	0.667	0.587	Glyco_hydro_20 (PF00728, IPR015883): Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b (PF02838, IPR015882): Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 (PF14845, IPR029019): beta-acetyl hexosaminidase like
98	HIRA	suppressor	5	0.700	0.741	Hira (PF07569, IPR011494): TUP1-like enhancer of split HIRA_B (PF09453, IPR019015): HIRA B motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
99	HMGA1	oncoprotein	19	0.485	25.352	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
100	HNRNPA0	interactor	48	0.506	84.428	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
101	HNRNPA1	interactor	104	0.315	1008.784	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
102	HNRNPA2B1	oncoprotein	70	0.342	340.559	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
103	HNRNPA3	oncoprotein	60	0.459	142.448	IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
104	HNRNPAB	interactor	56	0.392	197.676	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
105	HNRNPC	protein found in more fusions	50	0.300	200.098	APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
106	HNRNPCL1	interactor	14	0.549	4.129	FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XhlA (PF10779, IPR019715): Haemolysin XhlA
107	HNRNPDL	interactor	55	0.415	271.361	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
108	HNRNPF	interactor	53	0.488	92.042	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
109	HNRNPH1	oncoprotein	71	0.386	349.601	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
110	HNRNPH2	interactor	46	0.482	117.869	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
111	HNRNPH3	protein found in more fusions	45	0.518	74.921	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
112	HNRNPK	oncoprotein	71	0.396	259.856	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
113	HNRNPL	protein found in more fusions	48	0.476	146.251	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
114	HNRNPR	interactor	57	0.435	178.802	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
115	HNRNPU	interactor	87	0.301	896.395	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
116	HSD17B4	interactor	9	0.528	2.517	adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase
117	HSPA4	interactor	29	0.397	90.301	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
118	HSPA5	oncoprotein	69	0.395	317.332	HSP70 (PF00012, IPR013126): Hsp70 protein
119	HSPA6	interactor	11	0.618	2.407	HSP70 (PF00012, IPR013126): Hsp70 protein
120	HSPA8	oncoprotein	53	0.351	224.436	HSP70 (PF00012, IPR013126): Hsp70 protein
121	HSPA9	oncoprotein	45	0.397	107.539	HSP70 (PF00012, IPR013126): Hsp70 protein
122	HSPB1	oncoprotein	38	0.419	118.563	HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
123	HSPB2	interactor	9	0.250	15.852	Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
124	ICAM1	oncoprotein	15	0.495	7.029	Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
125	IFIT2	interactor	10	0.622	1.703	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
126	IFIT3	interactor	16	0.495	6.927	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
127	IGF2BP2	interactor	11	0.582	2.413	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain
128	IGSF8	oncoprotein	17	0.515	9.002	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
129	IL7R	interactor	20	0.511	8.224	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
130	IMMP2L	interactor	1	0	0	Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like Peptidase_S26 (PF10502, IPR019533): Signal peptidase, peptidase S26 DUF2798 (PF11391, IPR021529): Protein of unknown function (DUF2798)
131	IMMT	protein found in more fusions	13	0.455	13.402	Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
132	ING4	suppressor	3	1.000	0	PHD (PF00628, IPR019787, SM00249): PHD-finger SOGA (PF11365, IPR027881): Protein SOGA ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
133	INTS7	interactor	2	1.000	0	DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2 SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking
134	IPO11	interactor	5	0.600	0.449	DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein HEAT_2 (PF13646): HEAT repeats
135	ITGA4	interactor	63	0.271	354.659	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
136	ITGB4	oncoprotein	4	0.667	0.622	Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain SEA (PF01390, IPR000082, SM00200): SEA domain STOP (PF05217, IPR024963): STOP protein Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
137	IVNS1ABP	protein found in more fusions	22	0.443	24.288	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
138	KAT2B	protein found in more fusions	12	0.491	10.109	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
139	KHDRBS2	interactor	20	0.497	16.196	KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
140	KHSRP	interactor	26	0.452	24.368	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain
141	KIAA0368	interactor	8	0.679	3.858	HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
142	KLF16	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
143	KLHDC2	interactor	5	0.700	0.905	Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif Kelch_6 (PF13964): Kelch motif DUF4370 (PF14290, IPR025397): Domain of unknown function (DUF4370)
144	LSM5	interactor	1	0	0	LSM (PF01423, IPR001163): LSM domain
145	MAP2K1	oncoprotein	9	0.429	9.734	Pkinase (PF00069, IPR000719): Protein kinase domain DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
146	MAP3K4	suppressor	5	0.500	2.087	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pkinase (PF00069, IPR000719): Protein kinase domain PLU-1 (PF08429, IPR013637): PLU-1-like protein Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
147	MAPK6	oncoprotein	10	0.361	12.165	Pkinase (PF00069, IPR000719): Protein kinase domain
148	MCM2	oncoprotein	76	0.308	537.804	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
149	MDM2	oncoprotein	32	0.342	90.575	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
150	MEOX2	interactor	2	1.000	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
151	MEPCE	interactor	25	0.520	30.696	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
152	MORC2	interactor	3	1.000	0	Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit zf-CW (PF07496, IPR011124): CW-type Zinc Finger EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
153	MOV10	interactor	36	0.276	188.109	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
154	MPP1	oncoprotein	3	0.667	0.400	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
155	MRPL12	protein found in more fusions	8	0.762	0.788	Ribosomal_L12 (PF00542, IPR013823): Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain
156	MRPL55	interactor	3	0.667	0.286	Mitoc_L55 (PF09776, IPR018615): Mitochondrial ribosomal protein L55
157	MSH2	suppressor	18	0.353	28.799	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain
158	MTA2	interactor	12	0.439	12.206	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
159	MTOR	oncoprotein	10	0.361	7.574	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
160	MYC	oncoprotein	43	0.245	309.279	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
161	MYEF2	interactor	6	0.467	0.502	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
162	MYH1	oncoprotein	3	1.000	0	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
163	NAA50	interactor	6	0.667	0.967	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
164	NCL	protein found in more fusions	52	0.278	172.395	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
165	NEDD8	interactor	46	0.524	67.219	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
166	NHS	interactor	3	0.667	0.087	Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 NHS (PF15273, IPR024845): NHS-like
167	NRP1	interactor	3	0.667	1.000	CUB (PF00431, IPR000859, SM00042): CUB domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain DUF3481 (PF11980, IPR022579): C-terminal domain of neuropilin glycoprotein
168	NTMT1	interactor	1	0	0	Methyltransf_PK (PF05891, IPR008576): AdoMet dependent proline di-methyltransferase
169	NTRK1	oncoprotein	113	0.183	2460.323	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
170	NXF1	interactor	45	0.267	308.270	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
171	OBSCN	oncoprotein	5	0.600	0.878	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain TOBE_2 (PF08402, IPR013611): TOBE domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
172	OBSL1	protein found in more fusions	63	0.277	309.048	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
173	OSBPL2	interactor	2	1.000	0	Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
174	P4HB	interactor	21	0.537	15.378	Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
175	PABPC1	oncoprotein	61	0.326	339.309	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
176	PAFAH1B3	interactor	7	0.467	0.559	Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
177	PAIP1	interactor	9	0.667	2.072	MIF4G (PF02854, IPR003890, SM00543): MIF4G domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
178	PAN2	interactor	26	0.366	29.494	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
179	PARK2	suppressor	36	0.304	198.304	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
180	PCBP1	oncoprotein	32	0.427	50.640	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
181	PCBP2	protein found in more fusions	32	0.443	47.390	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
182	PDCL	interactor	3	0.667	0.087	Phosducin (PF02114, IPR024253): Phosducin
183	PDLIM7	interactor	12	0.424	12.677	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
184	PDRG1	interactor	1	0	0	Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
185	PEX10	protein found in more fusions	4	1.000	0	Pex2_Pex12 (PF04757, IPR006845): Pex2 / Pex12 amino terminal region zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
186	PGK1	interactor	20	0.647	8.802	PGK (PF00162, IPR001576): Phosphoglycerate kinase
187	PICALM	oncoprotein	15	0.581	22.340	ANTH (PF07651, IPR011417): ANTH domain
188	PINX1	suppressor	3	1.000	0	G-patch (PF01585, IPR000467, SM00443): G-patch domain NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat
189	PKM	oncoprotein	32	0.385	72.275	PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
190	PKN3	interactor	3	0.667	0.057	HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
191	PLXNB1	oncoprotein	2	1.000	0	Plexin_cytopl (PF08337, IPR013548): Plexin cytoplasmic RasGAP domain PSI (PF01437, IPR002165, SM00423): Plexin repeat Sema (PF01403, IPR001627, SM00630): Sema domain TIG (PF01833, IPR002909): IPT/TIG domain
192	PNPLA8	interactor	3	0.667	0.087	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) SMC_ScpB (PF04079, IPR005234): Segregation and condensation complex subunit ScpB Patatin (PF01734, IPR002641): Patatin-like phospholipase
193	PPIH	interactor	7	0.533	0.512	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
194	PPM1A	suppressor	7	0.286	5.100	PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
195	PPOX	interactor	3	0.667	0.400	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
196	PPP1R18	interactor	4	0.667	2.000	Totivirus_coat (PF05518, IPR008871): Totivirus coat protein DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
197	PPP4R3B	interactor	5	0.700	0.789	Diphtheria_T (PF02764, IPR022405): Diphtheria toxin, T domain SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide WH1 (PF00568, IPR000697, SM00461): WH1 domain
198	PRDX3	interactor	19	0.333	14.235	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
199	PRMT3	interactor	5	0.700	0.759	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
200	PTBP1	oncoprotein	51	0.473	118.011	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
201	PTBP2	interactor	7	0.333	0.867	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
202	PTGR2	oncoprotein	2	1.000	0	ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase ADH_N_2 (PF16884): N-terminal domain of oxidoreductase
203	PTGS2	oncoprotein	6	0.900	0.167	An_peroxidase (PF03098, IPR002007): Animal haem peroxidase EGF (PF00008, IPR000742, SM00181): EGF-like domain
204	PYCR1	interactor	6	0.667	0.329	ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation
205	RALY	interactor	27	0.647	12.935	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
206	RASIP1	interactor	2	1.000	0	DIL (PF01843, IPR018444, SM01132): DIL domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
207	RBM4	suppressor	33	0.511	43.862	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN
208	RBM8A	interactor	12	0.400	12.919	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
209	RBMX	suppressor	44	0.396	118.882	RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
210	RET	oncoprotein	7	0.600	2.706	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
211	RMDN3	interactor	3	1.000	0	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_16 (PF13432): Tetratricopeptide repeat
212	RPA1	suppressor	47	0.482	104.421	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
213	RPA2	oncoprotein	43	0.466	100.910	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
214	RPA3	interactor	40	0.490	47.459	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
215	RPS12	interactor	14	0.484	7.224	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
216	RPS28	interactor	22	0.459	30.418	Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
217	RPSA	interactor	35	0.430	82.751	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
218	SAFB	suppressor	18	0.529	13.669	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
219	SAP18	interactor	8	0.607	2.441	SAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18)
220	SBF2	interactor	5	0.700	0.661	dDENN (PF03455, IPR005112, SM00801): dDENN domain DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain PH (PF00169, IPR001849, SM00233): PH domain uDENN (PF03456, IPR005113, SM00800): uDENN domain SBF2 (PF12335, IPR022096): Myotubularin protein
221	SCARNA22	interactor	21	0.471	13.132	NA
222	SDF2	interactor	2	1.000	0	MIR (PF02815, IPR016093, SM00472): MIR domain
223	SEPT9	oncoprotein	10	0.622	2.744	Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
224	SF3B4	interactor	18	0.556	14.023	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
225	SFN	suppressor	20	0.357	45.735	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
226	SFPQ	oncoprotein	44	0.378	111.548	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
227	SHISA5	interactor	2	1.000	0	Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
228	SIRT5	interactor	2	1.000	0	PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
229	SLC25A20	interactor	3	1.000	0	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
230	SLC27A5	interactor	1	0	0	AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
231	SLC30A5	oncoprotein	2	1.000	0	Cation_efflux (PF01545, IPR002524): Cation efflux family DUF4199 (PF13858, IPR025250): Protein of unknown function (DUF4199)
232	SLC3A2	interactor	10	0.644	1.203	Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459) SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
233	SMARCAD1	interactor	16	0.508	17.415	CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
234	SMURF1	interactor	31	0.338	84.898	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
235	SNAPC4	interactor	2	1.000	0	DUF111 (PF01969, IPR002822): Protein of unknown function DUF111 Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
236	SNRPC	interactor	21	0.562	19.259	zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
237	SNW1	protein found in more fusions	53	0.382	223.610	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
238	SREK1	protein found in more fusions	23	0.416	33.867	Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
239	SRSF10	interactor	15	0.429	14.497	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
240	SRSF6	oncoprotein	18	0.536	9.813	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Tox-HNH-EHHH (PF15657, IPR028048): HNH/Endo VII superfamily nuclease toxins
241	STAU1	protein found in more fusions	50	0.370	158.527	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
242	SYNCRIP	interactor	89	0.200	1930.916	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
243	TARBP1	interactor	5	0.400	1.669	SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
244	TARS	interactor	23	0.356	52.237	HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
245	TAX1BP1	interactor	4	0.667	1.083	CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 zf-C2H2_4 (PF13894): C2H2-type zinc finger PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
246	TLN1	interactor	17	0.449	10.086	DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
247	TLN2	interactor	2	1.000	0	FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
248	TMEM261	interactor	1	0	0	DUF4536 (PF15055, IPR028036): Domain of unknown function (DUF4536)
249	TNF	oncoprotein	9	0.393	12.238	TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
250	TNFRSF1A	oncoprotein	9	0.321	8.972	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
251	TOMM34	interactor	9	0.528	3.618	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SHNi-TPR (PF10516, IPR019544): SHNi-TPR TPR_12 (PF13424): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919)
252	TRN-GTT2-1	interactor	1	0	0	NA
253	TSEN34	interactor	2	1.000	0	Presenilin (PF01080, IPR001108): Presenilin tRNA_int_endo (PF01974, IPR006677): tRNA intron endonuclease, catalytic C-terminal domain
254	TUBB3	interactor	10	0.533	3.604	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
255	U2AF2	protein found in more fusions	58	0.428	182.947	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
256	UAP1	interactor	6	0.400	1.322	UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
257	UBE2G2	interactor	8	0.476	3.550	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
258	UBE2I	interactor	30	0.266	160.572	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
259	UHRF1BP1	interactor	4	0.500	1.004	Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13 VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal
260	UQCRC1	interactor	5	0.600	0.383	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
261	USP11	protein found in more fusions	15	0.308	33.479	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
262	USP24	oncoprotein	1	0	0	Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region GRP (PF07172, IPR010800): Glycine rich protein family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
263	VCAM1	interactor	56	0.251	267.131	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
264	VEGFA	suppressor	5	0.500	2.167	PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 VEGF_C (PF14554, IPR027928): VEGF heparin-binding domain
265	VHL	suppressor	38	0.416	121.242	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
266	WDR24	interactor	1	0	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
267	WNK1	interactor	9	0.393	10.655	SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pkinase (PF00069, IPR000719): Protein kinase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
268	YBX1	oncoprotein	47	0.360	160.378	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
269	ZNF286A	interactor	3	0.667	0.087	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3106 (PF11304, IPR021455): Protein of unknown function (DUF3106) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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