1 |
HNRNPD | parental protein | 269 | 0.076 | 42696.344 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
2 |
ABCA7 | interactor | 2 | 1.000 | 0 | ABC_tran (PF00005, IPR003439): ABC transporter ABC2_membrane_3 (PF12698): ABC-2 family transporter protein AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 (PF13732, IPR025302): Domain of unknown function (DUF4162) |
3 |
ABCC10 | interactor | 1 | 0 | 0 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
4 |
ACSL4 | interactor | 2 | 1.000 | 0 | AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain |
5 |
ACTB | oncoprotein | 42 | 0.332 | 114.630 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ADGRE5 | oncoprotein | 1 | 0 | 0 | 7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family) EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_MSP1_1 (PF12946, IPR024730): MSP1 EGF domain 1 |
7 |
AHNAK | suppressor | 23 | 0.537 | 12.341 | DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37 |
8 |
ARF4 | interactor | 9 | 0.500 | 4.941 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family |
9 |
ARHGAP32 | oncoprotein | 7 | 0.524 | 2.104 | PX (PF00787, IPR001683, SM00312): PX domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RPEL (PF02755, IPR004018, SM00707): RPEL repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain |
10 |
ARRB2 | interactor | 38 | 0.329 | 122.505 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
11 |
ASB2 | interactor | 13 | 0.652 | 7.463 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
12 |
AURKA | oncoprotein | 23 | 0.364 | 54.786 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
13 |
B3GAT3 | interactor | 3 | 1.000 | 0 | Glyco_transf_43 (PF03360, IPR005027): Glycosyltransferase family 43 |
14 |
BAG6 | interactor | 37 | 0.098 | 444.413 | DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
15 |
BANF1 | interactor | 9 | 0.286 | 5.874 | BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor |
16 |
BCL2 | oncoprotein | 6 | 0.700 | 0.694 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4 |
17 |
BET1L | interactor | 1 | 0 | 0 | CDV3 (PF15359, IPR026806): Carnitine deficiency-associated protein 3 |
18 |
BLMH | interactor | 8 | 0.524 | 2.705 | Peptidase_C1_2 (PF03051, IPR004134): Peptidase C1-like family |
19 |
BRCA1 | suppressor | 35 | 0.232 | 210.195 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
20 |
BTRC | oncoprotein | 24 | 0.368 | 49.500 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
21 |
C1QBP | interactor | 26 | 0.483 | 26.472 | MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053) |
22 |
C2CD5 | oncoprotein | 6 | 0.600 | 2.273 | C2 (PF00168, IPR000008, SM00239): C2 domain YbjQ_1 (PF01906, IPR002765): Putative heavy-metal-binding |
23 |
C2orf49 | interactor | 3 | 1.000 | 0 | Ashwin (PF15323, IPR024887): Developmental protein |
24 |
CAND1 | interactor | 75 | 0.363 | 384.619 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
25 |
CAPN1 | interactor | 13 | 0.564 | 8.897 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
26 |
CD4 | suppressor | 11 | 0.467 | 3.853 | ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region |
27 |
CD81 | interactor | 27 | 0.360 | 51.864 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
28 |
CDK2 | suppressor | 55 | 0.307 | 296.869 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CDK9 | protein found in more fusions | 23 | 0.489 | 29.160 | Pkinase (PF00069, IPR000719): Protein kinase domain |
30 |
CETN2 | interactor | 2 | 1.000 | 0 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
31 |
CHEK1 | suppressor | 12 | 0.409 | 14.148 | Pkinase (PF00069, IPR000719): Protein kinase domain |
32 |
CHMP5 | interactor | 5 | 0.667 | 0.733 | Snf7 (PF03357, IPR005024): Snf7 |
33 |
CINP | interactor | 1 | 0 | 0 | Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 |
34 |
COG2 | interactor | 3 | 1.000 | 0 | COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Syntaxin_2 (PF14523): Syntaxin-like protein |
35 |
COG7 | interactor | 5 | 0.700 | 2.000 | COG7 (PF10191, IPR019335): Golgi complex component 7 (COG7) |
36 |
COL18A1 | oncoprotein | 2 | 1.000 | 0 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF959 (PF06121, IPR010363): Domain of Unknown Function (DUF959) Endostatin (PF06482, IPR010515): Collagenase NC10 and Endostatin Fz (PF01392, IPR020067, SM00063): Fz domain Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily |
37 |
COPS5 | protein found in more fusions | 77 | 0.338 | 574.518 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
38 |
COPS6 | interactor | 40 | 0.511 | 96.824 | DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
39 |
CTSB | oncoprotein | 3 | 0.667 | 1.000 | Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease Propeptide_C1 (PF08127, IPR012599): Peptidase family C1 propeptide |
40 |
CUL1 | suppressor | 81 | 0.336 | 545.704 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
41 |
CUL2 | suppressor | 55 | 0.411 | 188.256 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
42 |
CUL3 | protein found in more fusions | 90 | 0.286 | 874.157 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
43 |
CUL4A | protein found in more fusions | 35 | 0.512 | 81.058 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
44 |
CUL4B | oncoprotein | 48 | 0.485 | 106.270 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
45 |
CUL5 | suppressor | 56 | 0.457 | 152.951 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
46 |
CUL7 | protein found in more fusions | 69 | 0.248 | 431.704 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
47 |
CUTA | interactor | 2 | 1.000 | 0 | CutA1 (PF03091, IPR004323): CutA1 divalent ion tolerance protein |
48 |
DCUN1D1 | interactor | 37 | 0.632 | 39.359 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
49 |
DDX1 | oncoprotein | 42 | 0.437 | 110.248 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
50 |
DDX51 | interactor | 1 | 0 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3330 (PF11809, IPR021767): Domain of unknown function (DUF3330) FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
51 |
DENR | oncoprotein | 3 | 0.667 | 0.057 | SUI1 (PF01253, IPR001950): Translation initiation factor SUI1 |
52 |
DGCR2 | interactor | 1 | 0 | 0 | UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A |
53 |
DHX30 | interactor | 19 | 0.585 | 7.319 | Bombolitin (PF08096, IPR012534): Bombolitin family DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
54 |
DICER1 | suppressor | 7 | 0.600 | 0.930 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
55 |
DKC1 | oncoprotein | 18 | 0.301 | 31.197 | DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain PUA (PF01472, IPR002478, SM00359): PUA domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain |
56 |
DNAJC7 | interactor | 13 | 0.500 | 10.397 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat |
57 |
DNM2 | interactor | 11 | 0.436 | 11.679 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
58 |
DYNC1H1 | interactor | 25 | 0.497 | 23.106 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
59 |
DYSF | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain FerA (PF08165, IPR012560): FerA (NUC095) domain FerB (PF08150, IPR012561): FerB (NUC096) domain FerI (PF08151, IPR012968): FerI (NUC094) domain Pex24p (PF06398, IPR010482): Integral peroxisomal membrane peroxin Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
60 |
EED | suppressor | 49 | 0.313 | 189.221 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
61 |
EEF2 | interactor | 36 | 0.502 | 59.425 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
62 |
EIF3K | interactor | 10 | 0.511 | 8.670 | CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family |
63 |
EIF4G1 | oncoprotein | 13 | 0.551 | 2.665 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) MA3 (PF02847, IPR003891, SM00544): MA3 domain MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon |
64 |
EIF6 | interactor | 14 | 0.560 | 10.902 | eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family |
65 |
ENO1 | oncoprotein | 35 | 0.393 | 87.941 | Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain |
66 |
ERG | oncoprotein | 18 | 0.418 | 10.047 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
67 |
ERI1 | interactor | 1 | 0 | 0 | RNase_T (PF00929, IPR013520): Exonuclease SAP (PF02037, IPR003034, SM00513): SAP domain |
68 |
ESPL1 | interactor | 5 | 0.600 | 0.531 | Peptidase_C50 (PF03568, IPR005314): Peptidase family C50 |
69 |
ESR1 | suppressor | 55 | 0.308 | 256.185 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
70 |
ETFA | interactor | 8 | 0.393 | 8.738 | ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain |
71 |
EWSR1 | oncoprotein | 51 | 0.374 | 230.813 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
72 |
EXOSC4 | interactor | 9 | 0.536 | 7.021 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2 |
73 |
FAM120A | interactor | 12 | 0.788 | 1.239 | TPR_15 (PF13429): Tetratricopeptide repeat |
74 |
FANCD2 | oncoprotein | 8 | 0.500 | 6.974 | FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease |
75 |
FBXL15 | interactor | 4 | 0.667 | 0.217 | LRV (PF01816, IPR004830): Leucine rich repeat variant F-box (PF00646, IPR001810, SM00256): F-box domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
76 |
FBXW11 | interactor | 39 | 0.334 | 194.397 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
77 |
FLNA | suppressor | 35 | 0.264 | 136.484 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
78 |
FN1 | oncoprotein | 76 | 0.239 | 632.552 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
79 |
FNDC3A | interactor | 3 | 0.667 | 0.087 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Reeler (PF02014, IPR002861): Reeler domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
80 |
FUBP3 | interactor | 20 | 0.484 | 15.793 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
81 |
FUS | suppressor | 70 | 0.361 | 503.946 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
82 |
GCFC2 | interactor | 2 | 1.000 | 0 | DUF1676 (PF07898, IPR012464): Protein of unknown function (DUF1676) GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein |
83 |
GOLGA4 | interactor | 2 | 1.000 | 0 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DivIC (PF04977, IPR007060): Septum formation initiator DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Fez1 (PF06818): Fez1 FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) GRIP (PF01465, IPR000237, SM00755): GRIP domain Mnd1 (PF03962, IPR005647): Mnd1 family Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SlyX (PF04102, IPR007236): SlyX Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 XhlA (PF10779, IPR019715): Haemolysin XhlA YlqD (PF11068, IPR021297): YlqD protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_13 (PF16925, IPR011075): Bacterial transcriptional repressor C-terminal |
84 |
GPBP1 | interactor | 1 | 0 | 0 | ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL Vasculin (PF15337, IPR028128): Vascular protein family Vasculin-like 1 |
85 |
GPN1 | interactor | 9 | 0.667 | 1.744 | ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein NB-ARC (PF00931, IPR002182): NB-ARC domain |
86 |
GPRIN1 | interactor | 2 | 1.000 | 0 | GRIN_C (PF15235, IPR032745): G protein-regulated inducer of neurite outgrowth C-terminus |
87 |
GRB2 | oncoprotein | 32 | 0.368 | 131.562 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
88 |
GTF2IRD1 | interactor | 6 | 0.400 | 3.352 | GTF2I (PF02946, IPR004212): GTF2I-like repeat SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
89 |
GTF3C3 | interactor | 5 | 0.600 | 0.593 | BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat |
90 |
GTSE1 | interactor | 4 | 0.667 | 1.667 | GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1 |
91 |
GUK1 | interactor | 3 | 0.667 | 0.074 | Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
92 |
H2AFX | suppressor | 30 | 0.287 | 98.915 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
93 |
HBZ | interactor | 5 | 0.600 | 0.431 | Globin (PF00042, IPR000971): Globin |
94 |
HDAC1 | suppressor | 20 | 0.368 | 40.199 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
95 |
HDAC5 | protein found in more fusions | 36 | 0.339 | 93.811 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
96 |
HEATR3 | interactor | 2 | 1.000 | 0 | HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
97 |
HEXA | interactor | 4 | 0.667 | 0.587 | Glyco_hydro_20 (PF00728, IPR015883): Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b (PF02838, IPR015882): Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 (PF14845, IPR029019): beta-acetyl hexosaminidase like |
98 |
HIRA | suppressor | 5 | 0.700 | 0.741 | Hira (PF07569, IPR011494): TUP1-like enhancer of split HIRA_B (PF09453, IPR019015): HIRA B motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
99 |
HMGA1 | oncoprotein | 19 | 0.485 | 25.352 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
100 |
HNRNPA0 | interactor | 48 | 0.506 | 84.428 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
101 |
HNRNPA1 | interactor | 104 | 0.315 | 1008.784 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
102 |
HNRNPA2B1 | oncoprotein | 70 | 0.342 | 340.559 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
103 |
HNRNPA3 | oncoprotein | 60 | 0.459 | 142.448 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
104 |
HNRNPAB | interactor | 56 | 0.392 | 197.676 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
105 |
HNRNPC | protein found in more fusions | 50 | 0.300 | 200.098 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
106 |
HNRNPCL1 | interactor | 14 | 0.549 | 4.129 | FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XhlA (PF10779, IPR019715): Haemolysin XhlA |
107 |
HNRNPDL | interactor | 55 | 0.415 | 271.361 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
108 |
HNRNPF | interactor | 53 | 0.488 | 92.042 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
109 |
HNRNPH1 | oncoprotein | 71 | 0.386 | 349.601 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
110 |
HNRNPH2 | interactor | 46 | 0.482 | 117.869 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
111 |
HNRNPH3 | protein found in more fusions | 45 | 0.518 | 74.921 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
112 |
HNRNPK | oncoprotein | 71 | 0.396 | 259.856 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
113 |
HNRNPL | protein found in more fusions | 48 | 0.476 | 146.251 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
114 |
HNRNPR | interactor | 57 | 0.435 | 178.802 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
115 |
HNRNPU | interactor | 87 | 0.301 | 896.395 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
116 |
HSD17B4 | interactor | 9 | 0.528 | 2.517 | adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase |
117 |
HSPA4 | interactor | 29 | 0.397 | 90.301 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
118 |
HSPA5 | oncoprotein | 69 | 0.395 | 317.332 | HSP70 (PF00012, IPR013126): Hsp70 protein |
119 |
HSPA6 | interactor | 11 | 0.618 | 2.407 | HSP70 (PF00012, IPR013126): Hsp70 protein |
120 |
HSPA8 | oncoprotein | 53 | 0.351 | 224.436 | HSP70 (PF00012, IPR013126): Hsp70 protein |
121 |
HSPA9 | oncoprotein | 45 | 0.397 | 107.539 | HSP70 (PF00012, IPR013126): Hsp70 protein |
122 |
HSPB1 | oncoprotein | 38 | 0.419 | 118.563 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
123 |
HSPB2 | interactor | 9 | 0.250 | 15.852 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
124 |
ICAM1 | oncoprotein | 15 | 0.495 | 7.029 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
125 |
IFIT2 | interactor | 10 | 0.622 | 1.703 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein |
126 |
IFIT3 | interactor | 16 | 0.495 | 6.927 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
127 |
IGF2BP2 | interactor | 11 | 0.582 | 2.413 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
128 |
IGSF8 | oncoprotein | 17 | 0.515 | 9.002 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
129 |
IL7R | interactor | 20 | 0.511 | 8.224 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
130 |
IMMP2L | interactor | 1 | 0 | 0 | Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like Peptidase_S26 (PF10502, IPR019533): Signal peptidase, peptidase S26 DUF2798 (PF11391, IPR021529): Protein of unknown function (DUF2798) |
131 |
IMMT | protein found in more fusions | 13 | 0.455 | 13.402 | Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
132 |
ING4 | suppressor | 3 | 1.000 | 0 | PHD (PF00628, IPR019787, SM00249): PHD-finger SOGA (PF11365, IPR027881): Protein SOGA ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H (PF13771): PHD-like zinc-binding domain |
133 |
INTS7 | interactor | 2 | 1.000 | 0 | DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2 SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking |
134 |
IPO11 | interactor | 5 | 0.600 | 0.449 | DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein HEAT_2 (PF13646): HEAT repeats |
135 |
ITGA4 | interactor | 63 | 0.271 | 354.659 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
136 |
ITGB4 | oncoprotein | 4 | 0.667 | 0.622 | Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain SEA (PF01390, IPR000082, SM00200): SEA domain STOP (PF05217, IPR024963): STOP protein Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain |
137 |
IVNS1ABP | protein found in more fusions | 22 | 0.443 | 24.288 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
138 |
KAT2B | protein found in more fusions | 12 | 0.491 | 10.109 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
139 |
KHDRBS2 | interactor | 20 | 0.497 | 16.196 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
140 |
KHSRP | interactor | 26 | 0.452 | 24.368 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
141 |
KIAA0368 | interactor | 8 | 0.679 | 3.858 | HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
142 |
KLF16 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
143 |
KLHDC2 | interactor | 5 | 0.700 | 0.905 | Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif Kelch_6 (PF13964): Kelch motif DUF4370 (PF14290, IPR025397): Domain of unknown function (DUF4370) |
144 |
LSM5 | interactor | 1 | 0 | 0 | LSM (PF01423, IPR001163): LSM domain |
145 |
MAP2K1 | oncoprotein | 9 | 0.429 | 9.734 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216) |
146 |
MAP3K4 | suppressor | 5 | 0.500 | 2.087 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pkinase (PF00069, IPR000719): Protein kinase domain PLU-1 (PF08429, IPR013637): PLU-1-like protein Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958) |
147 |
MAPK6 | oncoprotein | 10 | 0.361 | 12.165 | Pkinase (PF00069, IPR000719): Protein kinase domain |
148 |
MCM2 | oncoprotein | 76 | 0.308 | 537.804 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
149 |
MDM2 | oncoprotein | 32 | 0.342 | 90.575 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
150 |
MEOX2 | interactor | 2 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
151 |
MEPCE | interactor | 25 | 0.520 | 30.696 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
152 |
MORC2 | interactor | 3 | 1.000 | 0 | Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit zf-CW (PF07496, IPR011124): CW-type Zinc Finger EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin |
153 |
MOV10 | interactor | 36 | 0.276 | 188.109 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
154 |
MPP1 | oncoprotein | 3 | 0.667 | 0.400 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase P33MONOX (PF15302, IPR026759): P33 mono-oxygenase |
155 |
MRPL12 | protein found in more fusions | 8 | 0.762 | 0.788 | Ribosomal_L12 (PF00542, IPR013823): Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain |
156 |
MRPL55 | interactor | 3 | 0.667 | 0.286 | Mitoc_L55 (PF09776, IPR018615): Mitochondrial ribosomal protein L55 |
157 |
MSH2 | suppressor | 18 | 0.353 | 28.799 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
158 |
MTA2 | interactor | 12 | 0.439 | 12.206 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
159 |
MTOR | oncoprotein | 10 | 0.361 | 7.574 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
160 |
MYC | oncoprotein | 43 | 0.245 | 309.279 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
161 |
MYEF2 | interactor | 6 | 0.467 | 0.502 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
162 |
MYH1 | oncoprotein | 3 | 1.000 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
163 |
NAA50 | interactor | 6 | 0.667 | 0.967 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
164 |
NCL | protein found in more fusions | 52 | 0.278 | 172.395 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
165 |
NEDD8 | interactor | 46 | 0.524 | 67.219 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
166 |
NHS | interactor | 3 | 0.667 | 0.087 | Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 NHS (PF15273, IPR024845): NHS-like |
167 |
NRP1 | interactor | 3 | 0.667 | 1.000 | CUB (PF00431, IPR000859, SM00042): CUB domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain DUF3481 (PF11980, IPR022579): C-terminal domain of neuropilin glycoprotein |
168 |
NTMT1 | interactor | 1 | 0 | 0 | Methyltransf_PK (PF05891, IPR008576): AdoMet dependent proline di-methyltransferase |
169 |
NTRK1 | oncoprotein | 113 | 0.183 | 2460.323 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
170 |
NXF1 | interactor | 45 | 0.267 | 308.270 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
171 |
OBSCN | oncoprotein | 5 | 0.600 | 0.878 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain TOBE_2 (PF08402, IPR013611): TOBE domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
172 |
OBSL1 | protein found in more fusions | 63 | 0.277 | 309.048 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
173 |
OSBPL2 | interactor | 2 | 1.000 | 0 | Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein |
174 |
P4HB | interactor | 21 | 0.537 | 15.378 | Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
175 |
PABPC1 | oncoprotein | 61 | 0.326 | 339.309 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
176 |
PAFAH1B3 | interactor | 7 | 0.467 | 0.559 | Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family |
177 |
PAIP1 | interactor | 9 | 0.667 | 2.072 | MIF4G (PF02854, IPR003890, SM00543): MIF4G domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
178 |
PAN2 | interactor | 26 | 0.366 | 29.494 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
179 |
PARK2 | suppressor | 36 | 0.304 | 198.304 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
180 |
PCBP1 | oncoprotein | 32 | 0.427 | 50.640 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
181 |
PCBP2 | protein found in more fusions | 32 | 0.443 | 47.390 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
182 |
PDCL | interactor | 3 | 0.667 | 0.087 | Phosducin (PF02114, IPR024253): Phosducin |
183 |
PDLIM7 | interactor | 12 | 0.424 | 12.677 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
184 |
PDRG1 | interactor | 1 | 0 | 0 | Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
185 |
PEX10 | protein found in more fusions | 4 | 1.000 | 0 | Pex2_Pex12 (PF04757, IPR006845): Pex2 / Pex12 amino terminal region zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
186 |
PGK1 | interactor | 20 | 0.647 | 8.802 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
187 |
PICALM | oncoprotein | 15 | 0.581 | 22.340 | ANTH (PF07651, IPR011417): ANTH domain |
188 |
PINX1 | suppressor | 3 | 1.000 | 0 | G-patch (PF01585, IPR000467, SM00443): G-patch domain NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat |
189 |
PKM | oncoprotein | 32 | 0.385 | 72.275 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
190 |
PKN3 | interactor | 3 | 0.667 | 0.057 | HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding |
191 |
PLXNB1 | oncoprotein | 2 | 1.000 | 0 | Plexin_cytopl (PF08337, IPR013548): Plexin cytoplasmic RasGAP domain PSI (PF01437, IPR002165, SM00423): Plexin repeat Sema (PF01403, IPR001627, SM00630): Sema domain TIG (PF01833, IPR002909): IPT/TIG domain |
192 |
PNPLA8 | interactor | 3 | 0.667 | 0.087 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) SMC_ScpB (PF04079, IPR005234): Segregation and condensation complex subunit ScpB Patatin (PF01734, IPR002641): Patatin-like phospholipase |
193 |
PPIH | interactor | 7 | 0.533 | 0.512 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
194 |
PPM1A | suppressor | 7 | 0.286 | 5.100 | PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
195 |
PPOX | interactor | 3 | 0.667 | 0.400 | Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase |
196 |
PPP1R18 | interactor | 4 | 0.667 | 2.000 | Totivirus_coat (PF05518, IPR008871): Totivirus coat protein DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal |
197 |
PPP4R3B | interactor | 5 | 0.700 | 0.789 | Diphtheria_T (PF02764, IPR022405): Diphtheria toxin, T domain SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide WH1 (PF00568, IPR000697, SM00461): WH1 domain |
198 |
PRDX3 | interactor | 19 | 0.333 | 14.235 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
199 |
PRMT3 | interactor | 5 | 0.700 | 0.759 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) |
200 |
PTBP1 | oncoprotein | 51 | 0.473 | 118.011 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
201 |
PTBP2 | interactor | 7 | 0.333 | 0.867 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
202 |
PTGR2 | oncoprotein | 2 | 1.000 | 0 | ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase ADH_N_2 (PF16884): N-terminal domain of oxidoreductase |
203 |
PTGS2 | oncoprotein | 6 | 0.900 | 0.167 | An_peroxidase (PF03098, IPR002007): Animal haem peroxidase EGF (PF00008, IPR000742, SM00181): EGF-like domain |
204 |
PYCR1 | interactor | 6 | 0.667 | 0.329 | ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation |
205 |
RALY | interactor | 27 | 0.647 | 12.935 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
206 |
RASIP1 | interactor | 2 | 1.000 | 0 | DIL (PF01843, IPR018444, SM01132): DIL domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain |
207 |
RBM4 | suppressor | 33 | 0.511 | 43.862 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN |
208 |
RBM8A | interactor | 12 | 0.400 | 12.919 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
209 |
RBMX | suppressor | 44 | 0.396 | 118.882 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
210 |
RET | oncoprotein | 7 | 0.600 | 2.706 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
211 |
RMDN3 | interactor | 3 | 1.000 | 0 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_16 (PF13432): Tetratricopeptide repeat |
212 |
RPA1 | suppressor | 47 | 0.482 | 104.421 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
213 |
RPA2 | oncoprotein | 43 | 0.466 | 100.910 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
214 |
RPA3 | interactor | 40 | 0.490 | 47.459 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
215 |
RPS12 | interactor | 14 | 0.484 | 7.224 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
216 |
RPS28 | interactor | 22 | 0.459 | 30.418 | Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e |
217 |
RPSA | interactor | 35 | 0.430 | 82.751 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus |
218 |
SAFB | suppressor | 18 | 0.529 | 13.669 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
219 |
SAP18 | interactor | 8 | 0.607 | 2.441 | SAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18) |
220 |
SBF2 | interactor | 5 | 0.700 | 0.661 | dDENN (PF03455, IPR005112, SM00801): dDENN domain DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain PH (PF00169, IPR001849, SM00233): PH domain uDENN (PF03456, IPR005113, SM00800): uDENN domain SBF2 (PF12335, IPR022096): Myotubularin protein |
221 |
SCARNA22 | interactor | 21 | 0.471 | 13.132 | NA |
222 |
SDF2 | interactor | 2 | 1.000 | 0 | MIR (PF02815, IPR016093, SM00472): MIR domain |
223 |
SEPT9 | oncoprotein | 10 | 0.622 | 2.744 | Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
224 |
SF3B4 | interactor | 18 | 0.556 | 14.023 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
225 |
SFN | suppressor | 20 | 0.357 | 45.735 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
226 |
SFPQ | oncoprotein | 44 | 0.378 | 111.548 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
227 |
SHISA5 | interactor | 2 | 1.000 | 0 | Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator |
228 |
SIRT5 | interactor | 2 | 1.000 | 0 | PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
229 |
SLC25A20 | interactor | 3 | 1.000 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
230 |
SLC27A5 | interactor | 1 | 0 | 0 | AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) |
231 |
SLC30A5 | oncoprotein | 2 | 1.000 | 0 | Cation_efflux (PF01545, IPR002524): Cation efflux family DUF4199 (PF13858, IPR025250): Protein of unknown function (DUF4199) |
232 |
SLC3A2 | interactor | 10 | 0.644 | 1.203 | Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459) SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus |
233 |
SMARCAD1 | interactor | 16 | 0.508 | 17.415 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
234 |
SMURF1 | interactor | 31 | 0.338 | 84.898 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
235 |
SNAPC4 | interactor | 2 | 1.000 | 0 | DUF111 (PF01969, IPR002822): Protein of unknown function DUF111 Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
236 |
SNRPC | interactor | 21 | 0.562 | 19.259 | zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger |
237 |
SNW1 | protein found in more fusions | 53 | 0.382 | 223.610 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
238 |
SREK1 | protein found in more fusions | 23 | 0.416 | 33.867 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
239 |
SRSF10 | interactor | 15 | 0.429 | 14.497 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
240 |
SRSF6 | oncoprotein | 18 | 0.536 | 9.813 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Tox-HNH-EHHH (PF15657, IPR028048): HNH/Endo VII superfamily nuclease toxins |
241 |
STAU1 | protein found in more fusions | 50 | 0.370 | 158.527 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
242 |
SYNCRIP | interactor | 89 | 0.200 | 1930.916 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
243 |
TARBP1 | interactor | 5 | 0.400 | 1.669 | SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family |
244 |
TARS | interactor | 23 | 0.356 | 52.237 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
245 |
TAX1BP1 | interactor | 4 | 0.667 | 1.083 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 zf-C2H2_4 (PF13894): C2H2-type zinc finger PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
246 |
TLN1 | interactor | 17 | 0.449 | 10.086 | DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
247 |
TLN2 | interactor | 2 | 1.000 | 0 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
248 |
TMEM261 | interactor | 1 | 0 | 0 | DUF4536 (PF15055, IPR028036): Domain of unknown function (DUF4536) |
249 |
TNF | oncoprotein | 9 | 0.393 | 12.238 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
250 |
TNFRSF1A | oncoprotein | 9 | 0.321 | 8.972 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
251 |
TOMM34 | interactor | 9 | 0.528 | 3.618 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SHNi-TPR (PF10516, IPR019544): SHNi-TPR TPR_12 (PF13424): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919) |
252 |
TRN-GTT2-1 | interactor | 1 | 0 | 0 | NA |
253 |
TSEN34 | interactor | 2 | 1.000 | 0 | Presenilin (PF01080, IPR001108): Presenilin tRNA_int_endo (PF01974, IPR006677): tRNA intron endonuclease, catalytic C-terminal domain |
254 |
TUBB3 | interactor | 10 | 0.533 | 3.604 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
255 |
U2AF2 | protein found in more fusions | 58 | 0.428 | 182.947 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
256 |
UAP1 | interactor | 6 | 0.400 | 1.322 | UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase |
257 |
UBE2G2 | interactor | 8 | 0.476 | 3.550 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
258 |
UBE2I | interactor | 30 | 0.266 | 160.572 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
259 |
UHRF1BP1 | interactor | 4 | 0.500 | 1.004 | Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13 VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal |
260 |
UQCRC1 | interactor | 5 | 0.600 | 0.383 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
261 |
USP11 | protein found in more fusions | 15 | 0.308 | 33.479 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
262 |
USP24 | oncoprotein | 1 | 0 | 0 | Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region GRP (PF07172, IPR010800): Glycine rich protein family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IMUP (PF15761, IPR026621): Immortalisation up-regulated protein |
263 |
VCAM1 | interactor | 56 | 0.251 | 267.131 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
264 |
VEGFA | suppressor | 5 | 0.500 | 2.167 | PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 VEGF_C (PF14554, IPR027928): VEGF heparin-binding domain |
265 |
VHL | suppressor | 38 | 0.416 | 121.242 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
266 |
WDR24 | interactor | 1 | 0 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type |
267 |
WNK1 | interactor | 9 | 0.393 | 10.655 | SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pkinase (PF00069, IPR000719): Protein kinase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal |
268 |
YBX1 | oncoprotein | 47 | 0.360 | 160.378 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
269 |
ZNF286A | interactor | 3 | 0.667 | 0.087 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3106 (PF11304, IPR021455): Protein of unknown function (DUF3106) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |