1 |
HNRNPA3 | parental protein | 113 | 0.243 | 3204.478 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
2 |
NONO | parental protein | 144 | 0.105 | 11585.460 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
3 |
AGMAT | interactor | 3 | 0.667 | 0.106 | Arginase (PF00491, IPR006035): Arginase family |
4 |
ALDH18A1 | interactor | 7 | 0.476 | 1.865 | AA_kinase (PF00696, IPR001048): Amino acid kinase family Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family |
5 |
APBB1 | interactor | 13 | 0.439 | 10.228 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
6 |
AR | oncoprotein | 26 | 0.270 | 124.740 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
7 |
ARHGDIA | interactor | 12 | 0.636 | 2.619 | Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor |
8 |
ARRB1 | interactor | 18 | 0.549 | 14.703 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
9 |
ARRB2 | interactor | 32 | 0.419 | 69.458 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
10 |
ASB18 | interactor | 3 | 0.333 | 1.455 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
11 |
ASB3 | interactor | 5 | 0.500 | 4.631 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
12 |
ATP1B1 | interactor | 9 | 0.417 | 8.545 | Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain |
13 |
ATP5B | interactor | 29 | 0.379 | 53.659 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
14 |
ATP6V0A1 | interactor | 3 | 0.333 | 3.639 | V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family |
15 |
BHLHE41 | suppressor | 7 | 0.533 | 7.519 | Adeno_PIX (PF03955, IPR005641): Adenovirus hexon-associated protein (IX) Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
16 |
BTRC | oncoprotein | 26 | 0.320 | 95.394 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
17 |
C11orf68 | interactor | 1 | 0 | 0 | DUF1917 (PF08939, IPR015034): Domain of unknown function (DUF1917) |
18 |
CA2 | interactor | 5 | 0.600 | 0.799 | Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase |
19 |
CAND1 | interactor | 73 | 0.362 | 628.703 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
20 |
CCDC8 | interactor | 41 | 0.365 | 173.308 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
21 |
CD81 | interactor | 24 | 0.478 | 72.117 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
22 |
CDC5L | interactor | 65 | 0.333 | 577.985 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
23 |
CHAF1A | interactor | 7 | 0.400 | 2.695 | CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA |
24 |
CHMP2A | interactor | 7 | 0.400 | 5.299 | Snf7 (PF03357, IPR005024): Snf7 |
25 |
CLK1 | interactor | 9 | 0.643 | 2.640 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
26 |
CNBP | oncoprotein | 10 | 0.467 | 11.944 | zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-ribbon_3 (PF13248): zinc-ribbon domain |
27 |
COPS5 | protein found in more fusions | 62 | 0.422 | 318.595 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
28 |
COX5A | interactor | 4 | 0.667 | 0.606 | COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va |
29 |
CPSF6 | interactor | 31 | 0.366 | 104.510 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
30 |
CRIP1 | interactor | 4 | 0.833 | 0.250 | LIM (PF00412, IPR001781, SM00132): LIM domain |
31 |
CRY1 | interactor | 24 | 0.379 | 85.500 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
32 |
CRY2 | protein found in more fusions | 22 | 0.352 | 76.894 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
33 |
CSTF2 | interactor | 10 | 0.467 | 23.293 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2 |
34 |
CTNNB1 | oncoprotein | 31 | 0.363 | 103.706 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
35 |
CTTN | oncoprotein | 20 | 0.409 | 51.748 | FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
36 |
CUL1 | suppressor | 69 | 0.391 | 424.926 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
37 |
CUL2 | suppressor | 41 | 0.567 | 78.738 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
38 |
CUL3 | protein found in more fusions | 90 | 0.288 | 1232.980 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
39 |
CUL4B | oncoprotein | 39 | 0.521 | 90.485 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
40 |
CUL5 | suppressor | 44 | 0.522 | 234.432 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
41 |
CUL7 | protein found in more fusions | 70 | 0.283 | 753.988 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
42 |
CYB5B | interactor | 4 | 0.667 | 0.382 | Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein |
43 |
DCUN1D1 | interactor | 31 | 0.703 | 40.665 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
44 |
DDX17 | protein found in more fusions | 66 | 0.340 | 404.248 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
45 |
DDX6 | oncoprotein | 19 | 0.421 | 21.478 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
46 |
DEC1 | suppressor | 10 | 0.472 | 13.284 | DEC1 (PF15859, IPR031718): Deleted in esophageal cancer 1 family |
47 |
DLD | interactor | 12 | 0.348 | 30.769 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain |
48 |
DYNC2H1 | interactor | 1 | 0 | 0 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1366 (PF07104, IPR009796): Protein of unknown function (DUF1366) DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Laminin_II (PF06009, IPR010307): Laminin Domain II AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
49 |
EED | suppressor | 60 | 0.300 | 379.956 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
50 |
EEF1G | protein found in more fusions | 31 | 0.377 | 60.959 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
51 |
EEF2 | interactor | 33 | 0.492 | 47.772 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
52 |
ELAVL1 | oncoprotein | 77 | 0.249 | 1410.436 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
53 |
EPS15 | oncoprotein | 15 | 0.462 | 33.454 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
54 |
ERG | oncoprotein | 21 | 0.519 | 21.400 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
55 |
ESR1 | suppressor | 58 | 0.267 | 606.815 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
56 |
EWSR1 | oncoprotein | 66 | 0.290 | 727.856 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
57 |
FBXW11 | interactor | 31 | 0.418 | 115.645 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
58 |
FDPS | interactor | 6 | 0.667 | 2.519 | polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase |
59 |
FN1 | oncoprotein | 67 | 0.296 | 553.148 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
60 |
FUS | suppressor | 68 | 0.383 | 572.849 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
61 |
FXR2 | interactor | 10 | 0.583 | 5.061 | Agenet (PF05641, IPR008395, SM00743): Agenet domain REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein) KH_1 (PF00013, IPR004088, SM00322): KH domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
62 |
GAPDH | oncoprotein | 40 | 0.379 | 83.134 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
63 |
GCN1 | interactor | 21 | 0.338 | 32.939 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
64 |
GORASP2 | interactor | 5 | 0.500 | 0.654 | GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain |
65 |
H2AFX | suppressor | 28 | 0.310 | 90.478 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
66 |
HABP4 | interactor | 4 | 0.500 | 1.175 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
67 |
HDAC1 | suppressor | 41 | 0.240 | 386.838 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
68 |
HDAC2 | suppressor | 38 | 0.281 | 235.800 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
69 |
HDAC3 | suppressor | 18 | 0.353 | 42.733 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
70 |
HDAC5 | protein found in more fusions | 38 | 0.351 | 153.383 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
71 |
HDGF | interactor | 17 | 0.463 | 15.008 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
72 |
HIST3H3 | interactor | 24 | 0.399 | 90.709 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
73 |
HNRNPA1 | interactor | 107 | 0.300 | 1843.019 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
74 |
HNRNPA1L2 | interactor | 12 | 0.576 | 10.086 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
75 |
HNRNPA2B1 | oncoprotein | 79 | 0.339 | 608.120 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
76 |
HNRNPAB | interactor | 52 | 0.392 | 236.191 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
77 |
HNRNPD | oncoprotein | 69 | 0.392 | 318.486 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
78 |
HNRNPDL | interactor | 48 | 0.535 | 95.387 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
79 |
HNRNPF | interactor | 58 | 0.430 | 204.171 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
80 |
HNRNPH1 | oncoprotein | 69 | 0.423 | 295.906 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
81 |
HNRNPH2 | interactor | 41 | 0.523 | 81.124 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
82 |
HNRNPH3 | protein found in more fusions | 50 | 0.418 | 172.768 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
83 |
HNRNPK | oncoprotein | 78 | 0.337 | 515.181 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
84 |
HNRNPL | protein found in more fusions | 54 | 0.474 | 211.574 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
85 |
HNRNPM | interactor | 63 | 0.336 | 393.773 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
86 |
HNRNPU | interactor | 83 | 0.319 | 746.535 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
87 |
HSD17B10 | interactor | 27 | 0.410 | 51.763 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
88 |
HSPA1A | interactor | 36 | 0.348 | 106.059 | HSP70 (PF00012, IPR013126): Hsp70 protein |
89 |
HSPA5 | oncoprotein | 65 | 0.399 | 321.182 | HSP70 (PF00012, IPR013126): Hsp70 protein |
90 |
HSPA8 | oncoprotein | 58 | 0.311 | 363.689 | HSP70 (PF00012, IPR013126): Hsp70 protein |
91 |
HUWE1 | oncoprotein | 41 | 0.313 | 192.196 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
92 |
IBA57 | interactor | 1 | 0 | 0 | GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain |
93 |
ICAM1 | oncoprotein | 15 | 0.486 | 7.850 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
94 |
IFIT3 | interactor | 10 | 0.750 | 0.963 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
95 |
IGSF8 | oncoprotein | 18 | 0.523 | 11.326 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
96 |
IL7R | interactor | 17 | 0.507 | 13.102 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
97 |
IRAK3 | interactor | 1 | 0 | 0 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
98 |
ITGA4 | interactor | 56 | 0.334 | 343.698 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
99 |
ITPA | protein found in more fusions | 5 | 0.500 | 2.643 | Ham1p_like (PF01725, IPR002637): Ham1 family |
100 |
KCND3 | interactor | 7 | 0.190 | 16.830 | Ion_trans (PF00520, IPR005821): Ion transport protein BTB_2 (PF02214, IPR003131): BTB/POZ domain Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3399 (PF11879, IPR024587): Domain of unknown function (DUF3399) |
101 |
KRAS | oncoprotein | 14 | 0.359 | 18.691 | Ras (PF00071, IPR001806, SM00173): Ras family |
102 |
LIN28A | interactor | 8 | 0.179 | 9.495 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_6 (PF15288): Zinc knuckle |
103 |
LMNA | protein found in more fusions | 36 | 0.329 | 152.952 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
104 |
LMO4 | interactor | 4 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger |
105 |
MAD1L1 | suppressor | 10 | 0.500 | 15.638 | MAD (PF05557, IPR008672): Mitotic checkpoint protein Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 |
106 |
MATR3 | interactor | 55 | 0.419 | 281.022 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
107 |
MCM2 | oncoprotein | 65 | 0.378 | 363.936 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
108 |
MCM5 | oncoprotein | 36 | 0.400 | 127.334 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
109 |
MRPL39 | interactor | 7 | 0.667 | 5.457 | TGS (PF02824, IPR004095): TGS domain DUF2469 (PF10611, IPR019592): Protein of unknown function (DUF2469) |
110 |
MRPL41 | interactor | 5 | 0.500 | 4.325 | MRP-L27 (PF09809, IPR019189): Mitochondrial ribosomal protein L27 |
111 |
MRPS26 | interactor | 6 | 0.467 | 0.986 | MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 |
112 |
MYC | oncoprotein | 42 | 0.250 | 335.059 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
113 |
NDUFS3 | protein found in more fusions | 18 | 0.309 | 65.011 | Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit |
114 |
NEDD8 | interactor | 38 | 0.586 | 43.116 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
115 |
NR2C1 | interactor | 10 | 0.711 | 3.173 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
116 |
NTRK1 | oncoprotein | 108 | 0.211 | 2769.340 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
117 |
NUP133 | oncoprotein | 10 | 0.378 | 5.190 | Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal |
118 |
NUP210 | interactor | 11 | 0.509 | 3.261 | Big_2 (PF02368, IPR003343, SM00635): Bacterial Ig-like domain (group 2) |
119 |
NUPR1 | suppressor | 4 | 0.833 | 0.498 | Phospho_p8 (PF10195, IPR018792): DNA-binding nuclear phosphoprotein p8 |
120 |
OBSL1 | interactor | 62 | 0.316 | 363.856 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
121 |
ORC5 | interactor | 8 | 0.571 | 2.647 | AAA_16 (PF13191): AAA ATPase domain ORC5_C (PF14630, IPR020796): Origin recognition complex (ORC) subunit 5 C-terminus |
122 |
PAN2 | interactor | 28 | 0.373 | 83.120 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
123 |
PARK2 | suppressor | 38 | 0.371 | 115.536 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
124 |
PARK7 | suppressor | 14 | 0.333 | 62.097 | DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family |
125 |
PGK1 | interactor | 25 | 0.477 | 68.034 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
126 |
PHB2 | interactor | 22 | 0.385 | 56.257 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
127 |
PHF6 | suppressor | 10 | 0.667 | 4.043 | zf-HC5HC2H (PF13771): PHD-like zinc-binding domain YqfQ (PF14181, IPR025571): YqfQ-like protein |
128 |
PIN1 | suppressor | 19 | 0.380 | 41.837 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
129 |
PITX3 | interactor | 3 | 1.000 | 0 | OAR (PF03826, IPR003654): OAR domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
130 |
PLEKHF2 | interactor | 3 | 0.667 | 0.496 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger PH (PF00169, IPR001849, SM00233): PH domain |
131 |
PMS1 | oncoprotein | 9 | 0.643 | 3.480 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HTH_Tnp_IS630 (PF01710, IPR002622): Transposase HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46 HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
132 |
POP1 | interactor | 13 | 0.455 | 24.791 | POP1 (PF06978, IPR009723): Ribonucleases P/MRP protein subunit POP1 POPLD (PF08170, IPR012590): POPLD (NUC188) domain |
133 |
PPP1CA | suppressor | 37 | 0.303 | 255.229 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
134 |
PPP1CB | interactor | 22 | 0.316 | 120.055 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
135 |
PPP1CC | oncoprotein | 24 | 0.355 | 91.644 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
136 |
PRKAA2 | suppressor | 3 | 0.667 | 0.133 | Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase |
137 |
PROSC | interactor | 7 | 0.619 | 1.957 | Ala_racemase_N (PF01168, IPR001608): Alanine racemase, N-terminal domain |
138 |
PRPF40A | protein found in more fusions | 35 | 0.467 | 68.354 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
139 |
PSMA3 | interactor | 29 | 0.365 | 90.986 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
140 |
PSPC1 | interactor | 17 | 0.309 | 29.140 | FUSC (PF04632, IPR006726): Fusaric acid resistance protein family NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zot (PF05707, IPR008900): Zonular occludens toxin (Zot) |
141 |
PTBP1 | oncoprotein | 56 | 0.463 | 199.857 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
142 |
PUF60 | protein found in more fusions | 33 | 0.488 | 49.410 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
143 |
RAB10 | oncoprotein | 12 | 0.485 | 6.375 | Ras (PF00071, IPR001806, SM00173): Ras family |
144 |
RAB1A | oncoprotein | 14 | 0.495 | 19.908 | Ras (PF00071, IPR001806, SM00173): Ras family |
145 |
RAB7A | suppressor | 19 | 0.409 | 75.805 | Ras (PF00071, IPR001806, SM00173): Ras family |
146 |
RAD21 | oncoprotein | 24 | 0.402 | 46.095 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
147 |
RALA | oncoprotein | 6 | 0.667 | 1.510 | ArgK (PF03308, IPR005129): ArgK protein Ras (PF00071, IPR001806, SM00173): Ras family ThiF (PF00899, IPR000594): ThiF family |
148 |
RALB | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
149 |
RNF2 | interactor | 47 | 0.239 | 357.251 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
150 |
RNF43 | oncoprotein | 4 | 0.333 | 5.745 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
151 |
RPA1 | suppressor | 54 | 0.439 | 325.723 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
152 |
RPA2 | oncoprotein | 49 | 0.434 | 260.759 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
153 |
RPA3 | interactor | 45 | 0.467 | 193.681 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
154 |
RPL36 | interactor | 22 | 0.416 | 56.716 | Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e |
155 |
RPLP2 | protein found in more fusions | 30 | 0.446 | 46.177 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
156 |
RPS13 | interactor | 31 | 0.368 | 77.861 | Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15 |
157 |
RPS28 | interactor | 22 | 0.528 | 21.010 | Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e |
158 |
RPS6KB2 | interactor | 16 | 0.375 | 12.078 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
159 |
RRM2 | interactor | 3 | 1.000 | 0 | Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain |
160 |
RSU1 | interactor | 3 | 0.667 | 0.036 | LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
161 |
SCARB2 | interactor | 2 | 1.000 | 0 | CD36 (PF01130, IPR002159): CD36 family |
162 |
SCARNA22 | interactor | 24 | 0.478 | 29.053 | NA |
163 |
SCO2 | interactor | 3 | 0.667 | 0.087 | SCO1-SenC (PF02630, IPR003782): SCO1/SenC |
164 |
SF3A2 | interactor | 27 | 0.499 | 40.936 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
165 |
SFN | suppressor | 20 | 0.398 | 66.823 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
166 |
SFPQ | oncoprotein | 82 | 0.234 | 1396.642 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
167 |
SIN3A | oncoprotein | 23 | 0.391 | 64.202 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
168 |
SIRT7 | interactor | 46 | 0.203 | 342.314 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
169 |
SLK | interactor | 3 | 1.000 | 0 | Pepsin-I3 (PF06394, IPR010480): Pepsin inhibitor-3-like repeated domain Pkinase (PF00069, IPR000719): Protein kinase domain TMPIT (PF07851, IPR012926): TMPIT-like protein TrbI_Ftype (PF09677, IPR014115): Type-F conjugative transfer system protein (TrbI_Ftype) PKK (PF12474, IPR022165): Polo kinase kinase |
170 |
SMARCA2 | suppressor | 16 | 0.600 | 11.835 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
171 |
SMARCA4 | suppressor | 27 | 0.373 | 65.955 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
172 |
SMARCAD1 | interactor | 20 | 0.526 | 22.246 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
173 |
SMARCB1 | suppressor | 20 | 0.409 | 30.471 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
174 |
SMARCC1 | suppressor | 23 | 0.433 | 40.182 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
175 |
SMARCD1 | interactor | 12 | 0.636 | 5.848 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
176 |
SMN1 | interactor | 21 | 0.432 | 25.005 | SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
177 |
SMURF1 | interactor | 25 | 0.424 | 21.391 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
178 |
SNRPA | interactor | 38 | 0.348 | 231.044 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
179 |
SNW1 | protein found in more fusions | 54 | 0.390 | 372.038 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
180 |
SOCS3 | suppressor | 5 | 0.600 | 3.095 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
181 |
SON | interactor | 19 | 0.439 | 28.238 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1 |
182 |
SPI1 | suppressor | 5 | 0.500 | 1.324 | Ets (PF00178, IPR000418, SM00413): Ets-domain p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain |
183 |
SQRDL | interactor | 3 | 0.333 | 0.728 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase |
184 |
SREK1 | protein found in more fusions | 17 | 0.617 | 16.655 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
185 |
SRPK2 | oncoprotein | 29 | 0.413 | 69.890 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
186 |
SRRM1 | interactor | 28 | 0.458 | 107.720 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
187 |
SRRM2 | interactor | 46 | 0.455 | 167.402 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
188 |
STAU1 | protein found in more fusions | 45 | 0.445 | 137.909 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
189 |
STK24 | interactor | 10 | 0.250 | 20.622 | DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain |
190 |
STRN4 | interactor | 3 | 0.333 | 6.498 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
191 |
SUGP2 | interactor | 8 | 0.357 | 9.175 | G-patch (PF01585, IPR000467, SM00443): G-patch domain Surp (PF01805, IPR000061, SM00648): Surp module |
192 |
SYNCRIP | interactor | 65 | 0.344 | 571.747 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
193 |
SYNPO | interactor | 7 | 0.571 | 3.883 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
194 |
TADA2A | interactor | 17 | 0.404 | 18.717 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
195 |
TARDBP | interactor | 50 | 0.498 | 130.350 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
196 |
TCERG1 | interactor | 26 | 0.446 | 53.908 | FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family |
197 |
TMED9 | interactor | 3 | 0.667 | 0.531 | EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD |
198 |
TOP1 | oncoprotein | 38 | 0.462 | 92.147 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
199 |
TOPORS | suppressor | 12 | 0.455 | 29.195 | Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
200 |
TP63 | suppressor | 15 | 0.407 | 16.085 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
201 |
TPM2 | protein found in more fusions | 8 | 0.429 | 10.477 | DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
202 |
TRIM24 | suppressor | 8 | 0.333 | 9.189 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) zf-MYND (PF01753, IPR002893): MYND finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 Imm68 (PF15583, IPR028276): Immunity protein 68 SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 |
203 |
TSG101 | suppressor | 10 | 0.500 | 4.476 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain |
204 |
U2AF2 | protein found in more fusions | 65 | 0.409 | 336.815 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
205 |
UBAC2 | interactor | 8 | 0.250 | 19.034 | Rhomboid (PF01694, IPR022764): Rhomboid family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
206 |
UBC | protein found in more fusions | 65 | 0.326 | 617.469 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
207 |
UBE2I | interactor | 31 | 0.264 | 247.381 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
208 |
UBE2N | protein found in more fusions | 11 | 0.333 | 24.702 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
209 |
UBQLN2 | protein found in more fusions | 12 | 0.618 | 4.370 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B |
210 |
UQCRC2 | oncoprotein | 16 | 0.267 | 57.741 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
211 |
USP37 | interactor | 16 | 0.314 | 37.257 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37 |
212 |
VCAM1 | interactor | 46 | 0.337 | 185.574 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
213 |
VHL | suppressor | 36 | 0.452 | 130.536 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
214 |
WBP4 | interactor | 11 | 0.545 | 5.082 | CDC45 (PF02724, IPR003874): CDC45-like protein WW (PF00397, IPR001202, SM00456): WW domain zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger TMCO5 (PF14992, IPR026617): TMCO5 family |
215 |
WWOX | suppressor | 31 | 0.284 | 107.681 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
216 |
XPO1 | interactor | 46 | 0.246 | 459.054 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
217 |
YLPM1 | interactor | 15 | 0.457 | 15.098 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit AAA_33 (PF13671): AAA domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
218 |
YWHAE | oncoprotein | 41 | 0.340 | 170.122 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
219 |
ZBTB1 | interactor | 8 | 0.286 | 5.557 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
220 |
ZC3H11A | interactor | 7 | 0.333 | 16.021 | Bul1_C (PF04426, IPR022794): Bul1 C terminus Sec62 (PF03839, IPR004728): Translocation protein Sec62 zf-CCCH_3 (PF15663): Zinc-finger containing family |
221 |
ZFAND6 | interactor | 3 | 0.667 | 0.496 | zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger |
222 |
ZNRD1 | interactor | 2 | 1.000 | 0 | RecR (PF02132, IPR023628): RecR protein RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) |