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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)69
The number (and %) of the onco-proteins22 (31.88 %)
The number (and %) of the tumor suppressors22 (31.88 %)
Total number of binary PPIs (saturation %)359 (15.30 %)
The number (and %) of affected PPIs69 (19.22 %)
The number of possible different fusions18
PPI diameter2
PPI radius1
The average degree of PPI9.507
Assortativity coefficient-0.3782
The network average Clustering coefficient0.546
The number (and %) of a zero Clustering coefficients11 (15.94 %)
The number (and %) of a zero Betweenness Centrality20 (28.99 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: HDAC7 All fusions
: AA286791;
Proteins found in more fusions UGP2 (see 1 fusions); IKZF1 (see 1 fusions); YWHAG (see 1 fusions); YWHAZ (see 1 fusions); EGFR (see 2 fusions); MARK3 (see 1 fusions); KAT5 (see 3 fusions); HDAC7 (see 1 fusions); HDAC5 (see 1 fusions); BCL6 (see 2 fusions); HDAC4 (see 1 fusions); MARK2 (see 2 fusions); HINT1 (see 3 fusions); PML (see 4 fusions); ZBTB16 (see 3 fusions); TBL1X (see 2 fusions); YWHAH (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HDAC7parental protein690.1142877.435Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
2 ACTN4interactor70.5246.587CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
3 ADNPinteractor21.0000zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
PHD_Oberon (PF07227, IPR032881): PHD - plant homeodomain finger protein
E6 (PF00518, IPR001334): Early Protein (E6)
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
4 AKAP12suppressor21.0000OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein
RII_binding_1 (PF10522, IPR018459): RII binding domain
WSK (PF03832, IPR001573): WSK motif
5 ARoncoprotein170.41741.051Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
6 BCL6oncoprotein110.7332.562BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
7 BCORL1suppressor31.0000Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region
PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
8 CALCOCO2interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
9 CASP8suppressor200DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
10 CTNNB1oncoprotein170.33152.251Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
11 DCAF10interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
12 EDNRAinteractor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
13 EGFRoncoprotein130.39427.132Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
14 ESR1suppressor210.42651.021Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
15 FLYWCH2interactor100FLYWCH_N (PF15423, IPR029279): FLYWCH-type zinc finger-containing protein
16 FOXA1suppressor21.0000Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
HNF_C (PF09354, IPR018533): HNF3 C-terminal domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
17 FOXP3suppressor80.5367.195Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
18 GNMTsuppressor200TehB (PF03848, IPR015985): Tellurite resistance protein TehB
Methyltransf_25 (PF13649): Methyltransferase domain
19 HDAC1suppressor240.33289.846FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
20 HDAC2suppressor180.30951.533Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
21 HDAC3suppressor200.40942.820Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
22 HDAC4oncoprotein320.305175.333Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
23 HDAC5protein found in more fusions370.249298.029Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
24 HIF1Asuppressor100.6673.626Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
25 HINT1suppressor40.6670.333HIT (PF01230, IPR001310): HIT domain
26 IKZF1suppressor110.6893.896Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
27 IKZF3suppressor100.6673.921C1_2 (PF03107, IPR004146): C1 domain
Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
28 IKZF4interactor80.8101.069ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
29 KAT5suppressor140.33333.821MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
30 KDM5Binteractor70.6671.510ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLU-1 (PF08429, IPR013637): PLU-1-like protein
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Rubredoxin (PF00301, IPR024935): Rubredoxin
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
Lipoprotein_20 (PF13942, IPR025262): YfhG lipoprotein
31 KLF4suppressor50.7000.690zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
32 MARK2protein found in more fusions100.9170.722DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
33 MARK3protein found in more fusions120.9091.167KA1 (PF02149, IPR001772): Kinase associated domain 1
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
34 MEF2Aoncoprotein80.6433.858TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
35 MEF2Concoprotein60.8670.833SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
36 MOCOSinteractor100Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
MOSC (PF03473, IPR005302): MOSC domain
MOSC_N (PF03476, IPR005303): MOSC N-terminal beta barrel domain
37 MOV10interactor50.5003.083AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
38 NCOR1oncoprotein160.54226.674BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
39 NCOR2oncoprotein150.6679.669CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
40 NR2E1interactor50.7000.537zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
41 NXF1interactor60.5001.650NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
42 PMLsuppressor140.51314.102zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
43 PPP1CBinteractor40.5002.500Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
44 PPP1R12Ainteractor21.0000DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
45 PPP2CAsuppressor50.7001.019Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
46 PRKD1oncoprotein51.0000PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
47 PRKD2interactor31.0000ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
48 RAP1GDS1oncoprotein40.5001.567Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
49 RELoncoprotein40.5002.400RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
50 RIPPLY1interactor21.0000E7 (PF00527, IPR000148): E7 protein, Early protein
Ripply (PF14998, IPR028127): Transcription Regulator
51 RUNX2suppressor70.7620.988DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Runt (PF00853, IPR013524): Runt domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
52 SFNsuppressor120.7095.93714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
53 SHMT2interactor50.8000.622SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
54 TBL1Xprotein found in more fusions90.7501.437K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
55 TBL1XR1oncoprotein110.7452.882LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
56 TTF2interactor100SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
zf-GRF (PF06839, IPR010666): GRF zinc finger
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
57 UBE2Iinteractor200.45639.908UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
58 UGP2protein found in more fusions200UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
59 WDR73interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
60 YWHABinteractor120.7426.86614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
61 YWHAEoncoprotein120.71212.74414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
62 YWHAGprotein found in more fusions130.7738.73314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
63 YWHAHprotein found in more fusions120.8363.56314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
64 YWHAQinteractor180.49741.37914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
65 YWHAZprotein found in more fusions200.43360.27814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
66 ZBTB16suppressor140.7444.250BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
67 ZFP36suppressor70.4764.967zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
68 ZMYM6interactor100Dimer_Tnp_hAT (PF05699, IPR008906): hAT family C-terminal dimerisation region
YHS (PF04945, IPR007029): YHS domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zinc_ribbon_5 (PF13719, IPR011723): zinc-ribbon domain
DUF4371 (PF14291, IPR025398): Domain of unknown function (DUF4371)
69 ZYG11Binteractor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
His_kinase (PF06580, IPR010559): Histidine kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTN4interactorCH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
AA286791
2 ADNPinteractorzf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
PHD_Oberon (PF07227, IPR032881): PHD - plant homeodomain finger protein
E6 (PF00518, IPR001334): Early Protein (E6)
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
AA286791
3 AKAP12suppressorOAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein
RII_binding_1 (PF10522, IPR018459): RII binding domain
WSK (PF03832, IPR001573): WSK motif
AA286791
4 ARoncoproteinAndrogen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
AA286791
5 CASP8suppressorDED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
AA286791
6 CTNNB1oncoproteinArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
AA286791
7 EDNRAinteractor7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)AA286791
8 EGFRoncoproteinFurin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
AA286791
9 FLYWCH2interactorFLYWCH_N (PF15423, IPR029279): FLYWCH-type zinc finger-containing proteinAA286791
10 FOXA1suppressorForkhead_N (PF08430, IPR013638): Forkhead N-terminal region
HNF_C (PF09354, IPR018533): HNF3 C-terminal domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
AA286791
11 GNMTsuppressorTehB (PF03848, IPR015985): Tellurite resistance protein TehB
Methyltransf_25 (PF13649): Methyltransferase domain
AA286791
12 HDAC1suppressorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
AA286791
13 HDAC2suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
AA286791
14 HDAC3suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domainAA286791
15 HDAC7parental proteinHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
AA286791
16 HINT1suppressorHIT (PF01230, IPR001310): HIT domainAA286791
17 IKZF1suppressorDesulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
AA286791
18 IKZF3suppressorC1_2 (PF03107, IPR004146): C1 domain
Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
AA286791
19 IKZF4interactorADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
AA286791
20 MARK2interactorDUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
AA286791
21 MARK3interactorKA1 (PF02149, IPR001772): Kinase associated domain 1
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
AA286791
22 MOCOSinteractorAminotran_5 (PF00266, IPR000192): Aminotransferase class-V
MOSC (PF03473, IPR005302): MOSC domain
MOSC_N (PF03476, IPR005303): MOSC N-terminal beta barrel domain
AA286791
23 MOV10interactorAAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
AA286791
24 NXF1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
AA286791
25 PMLsuppressorzf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
AA286791
26 PPP1CBinteractorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
AA286791
27 PPP1R12AinteractorDUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
AA286791
28 PPP2CAsuppressorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
AA286791
29 PRKD2interactorABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
AA286791
30 RAP1GDS1oncoproteinArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
AA286791
31 RIPPLY1interactorE7 (PF00527, IPR000148): E7 protein, Early protein
Ripply (PF14998, IPR028127): Transcription Regulator
AA286791
32 SFNsuppressor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
33 SHMT2interactorSHMT (PF00464, IPR001085): Serine hydroxymethyltransferaseAA286791
34 TBL1XinteractorK_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
AA286791
35 TBL1XR1oncoproteinLisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
AA286791
36 TTF2interactorSNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
zf-GRF (PF06839, IPR010666): GRF zinc finger
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AA286791
37 UBE2IinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzymeAA286791
38 UGP2interactorUDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferaseAA286791
39 YWHABinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
AA286791
40 YWHAEoncoprotein14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
41 YWHAGinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
42 YWHAHinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
43 YWHAQinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
44 YWHAZinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAA286791
45 ZFP36suppressorzf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)AA286791
46 ZMYM6interactorDimer_Tnp_hAT (PF05699, IPR008906): hAT family C-terminal dimerisation region
YHS (PF04945, IPR007029): YHS domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zinc_ribbon_5 (PF13719, IPR011723): zinc-ribbon domain
DUF4371 (PF14291, IPR025398): Domain of unknown function (DUF4371)
AA286791
47 ZYG11BinteractorArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
His_kinase (PF06580, IPR010559): Histidine kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
AA286791

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