1 |
HDAC5 | parental protein | 339 | 0.061 | 59605.149 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
2 |
ACAT1 | interactor | 10 | 0.389 | 11.283 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
3 |
ACLY | interactor | 8 | 0.500 | 6.984 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding |
4 |
ACTN4 | interactor | 15 | 0.324 | 39.114 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
5 |
ADAR | interactor | 9 | 0.694 | 1.622 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain |
6 |
AHCY | interactor | 7 | 0.733 | 0.253 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
7 |
AHRR | suppressor | 4 | 0.833 | 0.400 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold |
8 |
ALDH18A1 | interactor | 8 | 0.393 | 4.600 | AA_kinase (PF00696, IPR001048): Amino acid kinase family Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family |
9 |
ALDOA | interactor | 19 | 0.359 | 58.882 | Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I |
10 |
ANKRA2 | interactor | 8 | 0.464 | 7.893 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
11 |
APLP2 | interactor | 2 | 1.000 | 0 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding ELM2 (PF01448, IPR000949): ELM2 domain Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain Usp (PF00582, IPR006016): Universal stress protein family YL1 (PF05764, IPR008895): YL1 nuclear protein APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
12 |
APPL1 | interactor | 10 | 0.639 | 2.827 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region PH (PF00169, IPR001849, SM00233): PH domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) BAR_3 (PF16746): BAR domain of APPL family |
13 |
ATF3 | suppressor | 14 | 0.462 | 19.646 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
14 |
ATP1A1 | interactor | 16 | 0.550 | 21.608 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
15 |
ATP2A2 | interactor | 4 | 0.667 | 0.700 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase HAD (PF12710): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
16 |
ATP5A1 | protein found in more fusions | 39 | 0.317 | 201.814 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
17 |
ATP5B | interactor | 25 | 0.440 | 58.768 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
18 |
AURKB | interactor | 25 | 0.355 | 52.727 | Pkinase (PF00069, IPR000719): Protein kinase domain |
19 |
BAG2 | protein found in more fusions | 17 | 0.425 | 30.010 | IncA (PF04156, IPR007285): IncA protein Mnd1 (PF03962, IPR005647): Mnd1 family ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH |
20 |
BCL6 | oncoprotein | 16 | 0.448 | 30.110 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
21 |
BCORL1 | suppressor | 5 | 0.600 | 1.567 | Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain |
22 |
BRMS1 | suppressor | 11 | 0.600 | 4.015 | Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family Sds3 (PF08598, IPR013907): Sds3-like |
23 |
C1QBP | interactor | 26 | 0.286 | 98.672 | MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053) |
24 |
CAD | oncoprotein | 31 | 0.312 | 125.447 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
25 |
CAMK1 | interactor | 4 | 0.833 | 0.667 | Pkinase (PF00069, IPR000719): Protein kinase domain Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase |
26 |
CAMK2A | interactor | 7 | 0.400 | 2.118 | CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain Pkinase (PF00069, IPR000719): Protein kinase domain |
27 |
CAMTA2 | interactor | 1 | 0 | 0 | CG-1 (PF03859, IPR005559, SM01076): CG-1 domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif TIG (PF01833, IPR002909): IPT/TIG domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) PRIMA1 (PF16101): Proline-rich membrane anchor 1 dbPDZ_assoc (PF16610): Unstructured region between two PDZ domains on Dlg5 |
28 |
CAND1 | interactor | 97 | 0.172 | 1478.150 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
29 |
CANX | interactor | 27 | 0.359 | 71.799 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
30 |
CCAR2 | suppressor | 14 | 0.209 | 35.924 | DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide IncA (PF04156, IPR007285): IncA protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 DBC1 (PF14443, IPR025954, SM01122): DBC1 S1-like (PF14444, IPR025223): S1-like |
31 |
CCT2 | interactor | 33 | 0.473 | 78.179 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
32 |
CCT3 | interactor | 36 | 0.392 | 134.308 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
33 |
CCT4 | interactor | 29 | 0.480 | 56.682 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
34 |
CCT5 | interactor | 26 | 0.523 | 61.014 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
35 |
CCT6A | interactor | 32 | 0.460 | 79.957 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
36 |
CCT7 | interactor | 27 | 0.536 | 41.973 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
37 |
CCT8 | interactor | 26 | 0.578 | 30.343 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
38 |
CDC5L | interactor | 98 | 0.150 | 1782.380 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
39 |
CDK1 | oncoprotein | 20 | 0.374 | 47.565 | Pkinase (PF00069, IPR000719): Protein kinase domain |
40 |
CEP250 | interactor | 49 | 0.249 | 278.287 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
41 |
CIITA | oncoprotein | 7 | 0.333 | 5.924 | NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
42 |
CKB | interactor | 8 | 0.464 | 7.530 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
43 |
CKMT1B | interactor | 2 | 1.000 | 0 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
44 |
CLTC | oncoprotein | 34 | 0.374 | 114.620 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
45 |
COPB1 | protein found in more fusions | 15 | 0.341 | 23.060 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform |
46 |
COPB2 | interactor | 8 | 0.667 | 2.576 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
47 |
CS | interactor | 8 | 0.536 | 6.039 | Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain |
48 |
CSE1L | oncoprotein | 17 | 0.294 | 44.983 | CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
49 |
CSNK2A1 | oncoprotein | 47 | 0.226 | 350.624 | Pkinase (PF00069, IPR000719): Protein kinase domain |
50 |
CTBP1 | protein found in more fusions | 18 | 0.346 | 43.098 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
51 |
CUL7 | protein found in more fusions | 177 | 0.097 | 7727.064 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
52 |
DARS | interactor | 20 | 0.437 | 49.520 | tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain |
53 |
DDB1 | protein found in more fusions | 23 | 0.277 | 82.239 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
54 |
DDIT3 | oncoprotein | 7 | 0.533 | 3.319 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
55 |
DDOST | interactor | 20 | 0.458 | 41.423 | DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta |
56 |
DDX1 | oncoprotein | 21 | 0.457 | 31.783 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
57 |
DDX17 | protein found in more fusions | 30 | 0.426 | 59.524 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
58 |
DDX20 | interactor | 6 | 0.400 | 2.952 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
59 |
DDX39B | interactor | 13 | 0.423 | 16.245 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
60 |
DDX3X | suppressor | 25 | 0.397 | 68.943 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
61 |
DDX47 | interactor | 7 | 0.714 | 0.473 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
62 |
DHX15 | interactor | 29 | 0.490 | 50.026 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
63 |
DHX9 | oncoprotein | 37 | 0.375 | 135.191 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
64 |
DNAJA1 | interactor | 23 | 0.391 | 51.930 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
65 |
DNAJB11 | interactor | 8 | 0.500 | 5.798 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
66 |
DYRK1B | oncoprotein | 5 | 0.500 | 0.632 | Pkinase (PF00069, IPR000719): Protein kinase domain |
67 |
ECH1 | interactor | 4 | 0.500 | 1.267 | ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
68 |
EEF1G | protein found in more fusions | 20 | 0.351 | 51.392 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
69 |
EFTUD2 | interactor | 22 | 0.567 | 23.237 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
70 |
EIF3B | interactor | 10 | 0.467 | 14.802 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
71 |
EIF3C | oncoprotein | 14 | 0.571 | 12.844 | eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI (PF01399, IPR000717, SM00088): PCI domain |
72 |
EIF3F | suppressor | 7 | 0.905 | 0.686 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
73 |
EIF3L | interactor | 11 | 0.655 | 8.328 | Paf67 (PF10255, IPR019382): RNA polymerase I-associated factor PAF67 |
74 |
EIF4A1 | interactor | 16 | 0.550 | 14.200 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
75 |
EIF4A3 | interactor | 47 | 0.300 | 269.614 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
76 |
EMD | interactor | 30 | 0.276 | 122.435 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
77 |
EPRS | interactor | 21 | 0.371 | 51.359 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
78 |
ESR1 | suppressor | 124 | 0.140 | 3083.358 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
79 |
ETFA | interactor | 11 | 0.436 | 12.423 | ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain |
80 |
FASN | interactor | 13 | 0.621 | 3.723 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
81 |
FLNA | suppressor | 19 | 0.497 | 21.552 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
82 |
FXR1 | interactor | 6 | 0.500 | 1.155 | Agenet (PF05641, IPR008395, SM00743): Agenet domain KH_1 (PF00013, IPR004088, SM00322): KH domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 FXR_C3 (PF16097, IPR032177): Fragile X-related 1 protein C-terminal region 3 |
83 |
GABARAP | suppressor | 3 | 1.000 | 0 | Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like |
84 |
GANAB | suppressor | 10 | 0.578 | 4.699 | Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31 Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like DUF5110 (PF17137): Domain of unknown function (DUF5110) |
85 |
GATA1 | oncoprotein | 9 | 0.500 | 9.397 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
86 |
GATA2 | oncoprotein | 4 | 0.833 | 0.200 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
87 |
GATA3 | oncoprotein | 3 | 1.000 | 0 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
88 |
GCM1 | interactor | 6 | 0.600 | 2.523 | DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272) GCM (PF03615, IPR003902): GCM motif protein |
89 |
GCN1 | interactor | 11 | 0.491 | 6.578 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
90 |
GLUD1 | interactor | 4 | 0.833 | 0.019 | ELFV_dehydrog (PF00208, IPR006096, SM00839): Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SF3b10 (PF07189, IPR009846): Splicing factor 3B subunit 10 (SF3b10) |
91 |
GNB1 | interactor | 5 | 0.700 | 0.718 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
92 |
GNB2 | interactor | 10 | 0.511 | 8.057 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain |
93 |
GOT2 | oncoprotein | 2 | 1.000 | 0 | Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II |
94 |
GPS2 | oncoprotein | 10 | 0.667 | 2.420 | G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor |
95 |
H3F3A | oncoprotein | 18 | 0.386 | 32.446 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
96 |
HADHA | interactor | 9 | 0.611 | 4.250 | 3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
97 |
HAUS2 | interactor | 15 | 0.229 | 22.189 | DpnII (PF04556, IPR007637): DpnII restriction endonuclease HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2 |
98 |
HCFC1 | protein found in more fusions | 13 | 0.455 | 11.681 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
99 |
HDAC1 | suppressor | 81 | 0.125 | 1553.938 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
100 |
HDAC3 | suppressor | 63 | 0.143 | 827.731 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
101 |
HDAC4 | oncoprotein | 59 | 0.155 | 887.271 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
102 |
HDAC7 | protein found in more fusions | 37 | 0.249 | 266.738 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO |
103 |
HIF1A | suppressor | 21 | 0.419 | 40.409 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
104 |
HIST1H1C | oncoprotein | 16 | 0.400 | 18.799 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
105 |
HIST1H2BK | interactor | 3 | 1.000 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
106 |
HIST1H3A | interactor | 26 | 0.300 | 75.918 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
107 |
HIST2H2AC | interactor | 11 | 0.473 | 8.089 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
108 |
HIST3H3 | interactor | 28 | 0.294 | 99.706 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
109 |
HIST4H4 | interactor | 12 | 0.409 | 13.182 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
110 |
HNRNPA1 | interactor | 87 | 0.233 | 995.913 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
111 |
HNRNPA2B1 | oncoprotein | 31 | 0.424 | 74.000 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
112 |
HNRNPA3 | oncoprotein | 26 | 0.483 | 44.501 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
113 |
HNRNPD | oncoprotein | 36 | 0.339 | 149.349 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
114 |
HNRNPF | interactor | 26 | 0.471 | 57.551 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
115 |
HNRNPH2 | interactor | 21 | 0.547 | 19.934 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
116 |
HNRNPL | protein found in more fusions | 29 | 0.434 | 54.201 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
117 |
HNRNPLL | protein found in more fusions | 5 | 0.500 | 1.444 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
118 |
HNRNPR | interactor | 41 | 0.415 | 129.179 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
119 |
HOXC11 | oncoprotein | 2 | 1.000 | 0 | DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528) |
120 |
HR | interactor | 4 | 0.667 | 0.222 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase |
121 |
HSD17B10 | interactor | 18 | 0.379 | 39.487 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
122 |
HSP90AA1 | oncoprotein | 85 | 0.177 | 1382.904 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
123 |
HSP90AB1 | oncoprotein | 61 | 0.277 | 413.300 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
124 |
HSP90B1 | suppressor | 24 | 0.431 | 43.410 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
125 |
HSPA1A | interactor | 30 | 0.368 | 73.910 | HSP70 (PF00012, IPR013126): Hsp70 protein |
126 |
HSPA4 | interactor | 41 | 0.274 | 230.178 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
127 |
HSPA5 | oncoprotein | 57 | 0.271 | 383.912 | HSP70 (PF00012, IPR013126): Hsp70 protein |
128 |
HSPA9 | oncoprotein | 25 | 0.357 | 55.390 | HSP70 (PF00012, IPR013126): Hsp70 protein |
129 |
HSPD1 | suppressor | 24 | 0.420 | 44.315 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
130 |
IARS | interactor | 14 | 0.571 | 15.016 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
131 |
IGF2BP1 | oncoprotein | 8 | 0.500 | 1.554 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain |
132 |
IKZF1 | suppressor | 15 | 0.593 | 11.849 | Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
133 |
IKZF2 | suppressor | 8 | 0.810 | 0.863 | ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
134 |
IKZF3 | suppressor | 11 | 0.533 | 10.084 | C1_2 (PF03107, IPR004146): C1 domain Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_7 (PF15269): Zinc-finger |
135 |
IKZF4 | interactor | 9 | 0.679 | 2.359 | ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease |
136 |
ILF2 | interactor | 47 | 0.327 | 249.900 | DZF (PF07528, IPR006561, SM00572): DZF domain |
137 |
ILF3 | oncoprotein | 44 | 0.377 | 200.162 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
138 |
IMPDH2 | protein found in more fusions | 7 | 0.733 | 0.361 | IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain |
139 |
IRS4 | interactor | 20 | 0.363 | 39.037 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence PH_11 (PF15413): Pleckstrin homology domain |
140 |
JDP2 | suppressor | 4 | 0.667 | 0.062 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
141 |
KDM5B | interactor | 8 | 0.679 | 2.369 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Rubredoxin (PF00301, IPR024935): Rubredoxin zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger Lipoprotein_20 (PF13942, IPR025262): YfhG lipoprotein |
142 |
KLF4 | suppressor | 5 | 0.600 | 1.633 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
143 |
KPNB1 | protein found in more fusions | 26 | 0.263 | 103.306 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat |
144 |
LARS | interactor | 11 | 0.673 | 6.469 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
145 |
LDHA | interactor | 20 | 0.480 | 30.393 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
146 |
LGALS3BP | oncoprotein | 29 | 0.405 | 68.071 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
147 |
LRPPRC | interactor | 11 | 0.455 | 6.600 | DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR |
148 |
LTA4H | interactor | 3 | 1.000 | 0 | Leuk-A4-hydro_C (PF09127, IPR015211): Leukotriene A4 hydrolase, C-terminal Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 |
149 |
LTBR | oncoprotein | 2 | 0 | 0 | Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family |
150 |
MAFF | interactor | 5 | 0.667 | 0.786 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
151 |
MAP1B | interactor | 5 | 0.600 | 0.443 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) MAP1B_neuraxin (PF00414, IPR000102): Neuraxin and MAP1B repeat Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup Striatin (PF08232, IPR013258): Striatin family IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
152 |
MARK3 | protein found in more fusions | 13 | 0.697 | 8.230 | KA1 (PF02149, IPR001772): Kinase associated domain 1 Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
153 |
MARS | oncoprotein | 17 | 0.485 | 35.841 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain |
154 |
MCM2 | oncoprotein | 154 | 0.115 | 5389.361 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
155 |
MCM3 | interactor | 17 | 0.419 | 24.603 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
156 |
MCM4 | interactor | 17 | 0.450 | 25.728 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
157 |
MCM5 | oncoprotein | 46 | 0.261 | 279.365 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
158 |
MCM6 | interactor | 15 | 0.505 | 16.661 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 YmgB (PF10798, IPR024753): Biofilm development protein YmgB/AriR MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
159 |
MCM7 | protein found in more fusions | 24 | 0.320 | 70.176 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
160 |
MDH2 | protein found in more fusions | 7 | 0.667 | 2.452 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
161 |
MEF2A | oncoprotein | 16 | 0.400 | 31.541 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
162 |
MEF2C | oncoprotein | 6 | 0.867 | 0.533 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
163 |
MEF2D | oncoprotein | 9 | 0.444 | 5.908 | DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
164 |
MTA2 | interactor | 16 | 0.517 | 18.787 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
165 |
MTHFD1 | interactor | 14 | 0.440 | 21.694 | FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain |
166 |
MYCN | oncoprotein | 3 | 0.667 | 0.333 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
167 |
MYEF2 | interactor | 6 | 0.533 | 4.786 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
168 |
MYH9 | suppressor | 28 | 0.360 | 75.589 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
169 |
NCOR1 | oncoprotein | 31 | 0.318 | 117.574 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
170 |
NCOR2 | oncoprotein | 20 | 0.489 | 35.807 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
171 |
NEU1 | interactor | 1 | 0 | 0 | BNR_2 (PF13088, IPR011040): BNR repeat-like domain |
172 |
NFATC1 | oncoprotein | 15 | 0.400 | 25.774 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
173 |
NFKB1 | suppressor | 22 | 0.362 | 51.959 | Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
174 |
NFKBIA | oncoprotein | 15 | 0.495 | 17.804 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
175 |
NFKBIE | oncoprotein | 7 | 0.667 | 3.826 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
176 |
NFS1 | interactor | 2 | 1.000 | 0 | Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V |
177 |
NME1 | suppressor | 6 | 0.400 | 3.500 | NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase |
178 |
NONO | oncoprotein | 21 | 0.411 | 31.975 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
179 |
NOP2 | interactor | 19 | 0.579 | 16.032 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
180 |
NPEPPS | interactor | 5 | 0.600 | 2.476 | Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain |
181 |
NPM1 | suppressor | 80 | 0.223 | 965.223 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
182 |
NR2E1 | interactor | 4 | 0.833 | 0.040 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
183 |
NRIP1 | oncoprotein | 9 | 0.472 | 5.572 | ALMT (PF11744, IPR020966): Aluminium activated malate transporter NRIP1_repr_1 (PF15687, IPR031405): Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 (PF15688, IPR031406): Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 (PF15689, IPR031407): Nuclear receptor-interacting protein 1 repression 3 NRIP1_repr_4 (PF15690, IPR031408): Nuclear receptor-interacting protein 1 repression 4 |
184 |
NUDC | interactor | 8 | 0.464 | 7.697 | CS (PF04969, IPR007052): CS domain D5_N (PF08706, IPR014818, SM00885): D5 N terminal like Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc. NuDC (PF16273, IPR032572): Nuclear distribution C domain |
185 |
NUMA1 | oncoprotein | 14 | 0.451 | 16.580 | Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
186 |
NUP214 | oncoprotein | 9 | 0.571 | 2.262 | dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 |
187 |
NUP93 | oncoprotein | 7 | 0.524 | 4.532 | Nic96 (PF04097, IPR007231): Nup93/Nic96 |
188 |
OAT | interactor | 1 | 0 | 0 | Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III |
189 |
OGT | interactor | 7 | 0.429 | 5.352 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41 TPR_19 (PF14559): Tetratricopeptide repeat |
190 |
P4HB | interactor | 24 | 0.427 | 41.187 | Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
191 |
PA2G4 | interactor | 16 | 0.408 | 23.842 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
192 |
PABPC1 | oncoprotein | 43 | 0.377 | 171.066 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
193 |
PARP1 | suppressor | 33 | 0.306 | 124.683 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
194 |
PCBP2 | protein found in more fusions | 14 | 0.564 | 8.023 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
195 |
PCMT1 | interactor | 8 | 0.429 | 4.452 | PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) |
196 |
PCNA | oncoprotein | 27 | 0.243 | 105.078 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
197 |
PDIA6 | interactor | 14 | 0.385 | 26.884 | FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
198 |
PGAM5 | interactor | 4 | 0.833 | 0.667 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) |
199 |
PGK1 | interactor | 23 | 0.455 | 42.655 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
200 |
PHB | suppressor | 28 | 0.357 | 92.408 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
201 |
PHB2 | interactor | 26 | 0.234 | 142.852 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
202 |
PHGDH | interactor | 12 | 0.545 | 6.845 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
203 |
PKM | oncoprotein | 23 | 0.387 | 57.347 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
204 |
PKN1 | interactor | 7 | 0.533 | 2.441 | C2 (PF00168, IPR000008, SM00239): C2 domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
205 |
PKN2 | interactor | 14 | 0.423 | 21.119 | C2 (PF00168, IPR000008, SM00239): C2 domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
206 |
PPIA | interactor | 9 | 0.528 | 4.323 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
207 |
PPP1CA | suppressor | 26 | 0.305 | 88.558 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
208 |
PPP2CA | suppressor | 32 | 0.258 | 184.332 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
209 |
PPP2CB | suppressor | 17 | 0.654 | 20.261 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
210 |
PPP2R1A | oncoprotein | 35 | 0.296 | 166.275 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
211 |
PPP2R2A | interactor | 15 | 0.810 | 3.871 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
212 |
PPP2R2D | interactor | 15 | 0.790 | 5.328 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
213 |
PRDX3 | interactor | 7 | 0.533 | 3.755 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
214 |
PRDX4 | protein found in more fusions | 4 | 0.667 | 0.500 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
215 |
PRDX6 | protein found in more fusions | 7 | 0.733 | 1.139 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
216 |
PRKAA1 | suppressor | 21 | 0.252 | 91.334 | Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase |
217 |
PRKAB1 | oncoprotein | 5 | 0.400 | 3.233 | AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase |
218 |
PRKCD | suppressor | 14 | 0.372 | 23.347 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
219 |
PRKD1 | oncoprotein | 8 | 0.524 | 1.853 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
220 |
PRKD2 | interactor | 6 | 0.467 | 3.985 | ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
221 |
PRKD3 | interactor | 3 | 0.667 | 0.500 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
222 |
PRKDC | protein found in more fusions | 34 | 0.350 | 100.853 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
223 |
PRMT1 | interactor | 22 | 0.371 | 47.059 | Methyltransf_25 (PF13649): Methyltransferase domain |
224 |
PRMT5 | protein found in more fusions | 19 | 0.301 | 51.897 | PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase |
225 |
PRPF19 | protein found in more fusions | 26 | 0.507 | 41.396 | Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
226 |
PRPF39 | interactor | 2 | 1.000 | 0 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat |
227 |
PRPF8 | oncoprotein | 30 | 0.436 | 71.755 | PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core |
228 |
PSMA5 | oncoprotein | 18 | 0.438 | 35.942 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
229 |
PSMB5 | interactor | 16 | 0.500 | 27.985 | Proteasome (PF00227, IPR001353): Proteasome subunit |
230 |
PSMC4 | interactor | 17 | 0.529 | 24.677 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
231 |
PSMC5 | protein found in more fusions | 27 | 0.372 | 96.678 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
232 |
PSMC6 | interactor | 19 | 0.516 | 27.398 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
233 |
PSMD1 | interactor | 21 | 0.467 | 36.394 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
234 |
PSMD11 | interactor | 19 | 0.480 | 38.867 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
235 |
PSMD2 | oncoprotein | 19 | 0.497 | 36.376 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
236 |
PSMD3 | interactor | 15 | 0.610 | 17.279 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
237 |
PSMD6 | interactor | 12 | 0.818 | 2.743 | RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain |
238 |
PTBP1 | oncoprotein | 30 | 0.411 | 70.246 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
239 |
QARS | interactor | 23 | 0.383 | 65.822 | tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 |
240 |
RAD50 | interactor | 10 | 0.822 | 1.028 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region YscO (PF07321, IPR009929): Type III secretion protein YscO BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 DUF2703 (PF10865, IPR021219): Domain of unknown function (DUF2703) DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015) AAA_13 (PF13166, IPR026866): AAA domain AAA_23 (PF13476): AAA domain SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795) |
241 |
RAN | oncoprotein | 14 | 0.330 | 33.706 | Ras (PF00071, IPR001806, SM00173): Ras family |
242 |
RARS | interactor | 13 | 0.590 | 13.721 | Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain DivIC (PF04977, IPR007060): Septum formation initiator tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R) Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region |
243 |
RBBP4 | oncoprotein | 34 | 0.287 | 183.473 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
244 |
RBBP7 | suppressor | 19 | 0.404 | 45.434 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
245 |
RBM14 | suppressor | 23 | 0.474 | 40.099 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
246 |
RBM25 | interactor | 9 | 0.611 | 2.590 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PWI (PF01480, IPR002483, SM00311): PWI domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778) |
247 |
RBM39 | oncoprotein | 24 | 0.464 | 38.791 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
248 |
RBMX | suppressor | 23 | 0.593 | 17.456 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
249 |
REST | oncoprotein | 6 | 0.600 | 1.558 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Presenilin (PF01080, IPR001108): Presenilin RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain |
250 |
RFXANK | interactor | 8 | 0.333 | 7.452 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
251 |
RPL10A | interactor | 31 | 0.690 | 25.756 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
252 |
RPL13 | interactor | 32 | 0.637 | 34.696 | Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e |
253 |
RPL3 | interactor | 32 | 0.641 | 49.066 | Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3 |
254 |
RPL4 | interactor | 32 | 0.591 | 49.311 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
255 |
RPL5 | suppressor | 34 | 0.631 | 41.939 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
256 |
RPL7 | interactor | 38 | 0.542 | 72.027 | Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain |
257 |
RPL7A | interactor | 33 | 0.600 | 55.405 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
258 |
RPL9 | interactor | 28 | 0.672 | 45.944 | Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6 |
259 |
RPLP0 | interactor | 42 | 0.438 | 158.691 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
260 |
RPN1 | oncoprotein | 31 | 0.372 | 94.246 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
261 |
RPN2 | interactor | 16 | 0.483 | 16.226 | Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II |
262 |
RPS11 | interactor | 29 | 0.596 | 28.107 | Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal |
263 |
RPS3 | interactor | 46 | 0.471 | 122.882 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
264 |
RPS3A | interactor | 35 | 0.608 | 61.516 | Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family |
265 |
RPS4X | interactor | 38 | 0.553 | 83.382 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus |
266 |
RPS8 | interactor | 42 | 0.480 | 134.892 | Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e |
267 |
RPSA | interactor | 45 | 0.412 | 163.109 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus |
268 |
RUNX2 | suppressor | 12 | 0.500 | 9.426 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
269 |
RUNX3 | suppressor | 5 | 0.800 | 0.900 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain |
270 |
RUVBL1 | oncoprotein | 26 | 0.333 | 71.232 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
271 |
RUVBL2 | oncoprotein | 30 | 0.281 | 116.454 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
272 |
SF1 | protein found in more fusions | 18 | 0.287 | 47.551 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
273 |
SF3A1 | interactor | 28 | 0.423 | 74.636 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
274 |
SF3B1 | oncoprotein | 39 | 0.381 | 139.185 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
275 |
SF3B2 | interactor | 18 | 0.464 | 22.203 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
276 |
SF3B3 | interactor | 30 | 0.414 | 90.457 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
277 |
SFN | suppressor | 38 | 0.252 | 221.091 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
278 |
SFPQ | oncoprotein | 34 | 0.388 | 108.927 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
279 |
SFXN1 | interactor | 7 | 0.333 | 6.641 | Mtc (PF03820, IPR004686): Tricarboxylate carrier |
280 |
SHMT2 | interactor | 24 | 0.279 | 92.374 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
281 |
SIK1 | suppressor | 6 | 0.600 | 1.708 | Pkinase (PF00069, IPR000719): Protein kinase domain |
282 |
SIK2 | interactor | 15 | 0.381 | 21.890 | Pkinase (PF00069, IPR000719): Protein kinase domain |
283 |
SIK3 | oncoprotein | 10 | 0.533 | 7.273 | GET2 (PF08690, IPR028143): GET complex subunit GET2 Pkinase (PF00069, IPR000719): Protein kinase domain Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 |
284 |
SIN3A | oncoprotein | 37 | 0.252 | 247.258 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
285 |
SLC25A1 | interactor | 5 | 0.700 | 1.248 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
286 |
SLC25A11 | interactor | 5 | 0.667 | 0.472 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
287 |
SLC25A3 | interactor | 17 | 0.603 | 10.958 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
288 |
SLC25A6 | interactor | 6 | 0.733 | 0.428 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
289 |
SLC2A4RG | interactor | 2 | 0 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
290 |
SMAD3 | oncoprotein | 33 | 0.228 | 208.982 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
291 |
SMAD7 | interactor | 8 | 0.571 | 3.503 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
292 |
SMC1A | oncoprotein | 13 | 0.485 | 11.446 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
293 |
SMC3 | oncoprotein | 11 | 0.582 | 7.069 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
294 |
SNRNP200 | protein found in more fusions | 29 | 0.497 | 60.824 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
295 |
SRSF1 | protein found in more fusions | 33 | 0.458 | 62.652 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
296 |
STRAP | protein found in more fusions | 10 | 0.333 | 16.333 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
297 |
SUV39H1 | protein found in more fusions | 15 | 0.505 | 17.462 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain |
298 |
TAB2 | oncoprotein | 22 | 0.362 | 65.457 | CUE (PF02845, IPR003892, SM00546): CUE domain DivIC (PF04977, IPR007060): Septum formation initiator Mnd1 (PF03962, IPR005647): Mnd1 family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
299 |
TARS | interactor | 8 | 0.536 | 5.161 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
300 |
TBL1X | protein found in more fusions | 15 | 0.549 | 13.401 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family |
301 |
TBL1XR1 | oncoprotein | 14 | 0.615 | 8.649 | LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
302 |
TBX3 | oncoprotein | 4 | 0.667 | 0.040 | T-box (PF00907, IPR001699, SM00425): T-box TBX (PF12598, IPR022582): T-box transcription factor |
303 |
TCP1 | interactor | 33 | 0.460 | 77.678 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
304 |
TFEB | oncoprotein | 4 | 0.500 | 0.651 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DDRGK (PF09756, IPR019153, SM01128): DDRGK domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
305 |
TFRC | oncoprotein | 6 | 0.600 | 3.024 | PA (PF02225, IPR003137): PA domain Peptidase_M28 (PF04389, IPR007484): Peptidase family M28 TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain DUF3855 (PF12967, IPR024482): Domain of Unknown Function with PDB structure (DUF3855) |
306 |
TKT | protein found in more fusions | 17 | 0.350 | 32.760 | Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain |
307 |
TNPO1 | interactor | 5 | 0.600 | 1.008 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
308 |
TOP1 | oncoprotein | 36 | 0.411 | 96.740 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
309 |
TP53 | suppressor | 104 | 0.160 | 1983.480 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
310 |
TPI1 | interactor | 12 | 0.564 | 9.080 | TIM (PF00121, IPR000652): Triosephosphate isomerase |
311 |
TRAP1 | oncoprotein | 17 | 0.272 | 52.839 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
312 |
TRIM28 | protein found in more fusions | 35 | 0.258 | 176.643 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
313 |
TUBA1A | oncoprotein | 25 | 0.363 | 71.816 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
314 |
TUBB | interactor | 39 | 0.306 | 182.878 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
315 |
TUBB4B | interactor | 26 | 0.397 | 55.718 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
316 |
TUFM | interactor | 22 | 0.463 | 33.616 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
317 |
UBA1 | protein found in more fusions | 14 | 0.397 | 22.608 | ThiF (PF00899, IPR000594): ThiF family E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site |
318 |
UBE2I | interactor | 55 | 0.178 | 616.876 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
319 |
UPF1 | interactor | 17 | 0.537 | 18.613 | UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain |
320 |
UQCRC2 | oncoprotein | 33 | 0.294 | 134.121 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
321 |
USP7 | oncoprotein | 24 | 0.154 | 134.131 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
322 |
USP9X | interactor | 13 | 0.333 | 21.901 | DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain |
323 |
VCP | protein found in more fusions | 72 | 0.217 | 816.248 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
324 |
VDAC1 | interactor | 13 | 0.551 | 16.655 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
325 |
VDAC2 | interactor | 14 | 0.516 | 18.340 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
326 |
WDR5 | interactor | 17 | 0.279 | 49.124 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
327 |
XPO1 | interactor | 78 | 0.139 | 1456.227 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
328 |
XPOT | interactor | 3 | 0.667 | 0.667 | DUF310 (PF03750, IPR010149): Protein of unknown function (DUF310) IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
329 |
XRCC5 | suppressor | 25 | 0.420 | 51.318 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like |
330 |
XRCC6 | oncoprotein | 35 | 0.321 | 139.514 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
331 |
YWHAB | interactor | 26 | 0.425 | 61.430 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor |
332 |
YWHAE | oncoprotein | 50 | 0.296 | 289.649 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
333 |
YWHAG | protein found in more fusions | 32 | 0.340 | 120.869 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
334 |
YWHAH | protein found in more fusions | 16 | 0.648 | 10.857 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
335 |
YWHAQ | interactor | 65 | 0.196 | 774.501 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
336 |
YWHAZ | protein found in more fusions | 43 | 0.274 | 279.243 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
337 |
YY1 | protein found in more fusions | 23 | 0.307 | 57.038 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
338 |
ZBTB16 | suppressor | 23 | 0.403 | 72.403 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
339 |
ZBTB7B | interactor | 7 | 0.467 | 4.141 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |