1 |
GTF2E2 | parental protein | 35 | 0.143 | 711.467 | TFIIE_beta (PF02186, IPR003166): TFIIE beta subunit core domain VCX_VCY (PF15231, IPR026653): Variable charge X/Y family |
2 |
APP | protein found in more fusions | 12 | 0.273 | 33.967 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
3 |
ATF7IP | oncoprotein | 4 | 1.000 | 0 | TCP (PF03634, IPR005333): TCP family transcription factor DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951) ALMT (PF11744, IPR020966): Aluminium activated malate transporter ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain fn3_4 (PF16794, IPR003961): Fibronectin-III type domain |
4 |
CDK7 | oncoprotein | 7 | 0.600 | 4.000 | Pkinase (PF00069, IPR000719): Protein kinase domain |
5 |
DNM2 | interactor | 2 | 1.000 | 0 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
6 |
EEF1G | protein found in more fusions | 4 | 0.667 | 0.400 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
7 |
ERCC3 | oncoprotein | 7 | 0.571 | 6.500 | ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit DUF2748 (PF10871, IPR020183): Protein of unknown function (DUF2748) Helicase_C_3 (PF13625, IPR032830): Helicase conserved C-terminal domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase |
8 |
EXOC4 | oncoprotein | 1 | 0 | 0 | DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Vps51 (PF08700): Vps51/Vps67 |
9 |
FOS | oncoprotein | 7 | 0.800 | 1.300 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
10 |
GTF2A1 | oncoprotein | 6 | 0.600 | 4.400 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
11 |
GTF2B | interactor | 9 | 0.694 | 6.300 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
12 |
GTF2E1 | interactor | 13 | 0.410 | 32.633 | DUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980) TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding TFIIE_alpha (PF02002, IPR024550): TFIIE alpha subunit TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha |
13 |
GTF2F1 | interactor | 11 | 0.527 | 17.767 | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) |
14 |
GTF2F2 | interactor | 10 | 0.622 | 11.933 | TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit |
15 |
HNRNPA1 | interactor | 9 | 0.321 | 15.233 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
16 |
HSP90AB1 | oncoprotein | 6 | 0.500 | 3.167 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
17 |
JUN | oncoprotein | 10 | 0.639 | 7.433 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
18 |
KLF5 | suppressor | 5 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
19 |
MCC | suppressor | 2 | 1.000 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein |
20 |
MDM2 | oncoprotein | 8 | 0.429 | 9.733 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
21 |
MMS19 | interactor | 3 | 0.667 | 0.500 | DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
22 |
MOV10 | interactor | 3 | 0.667 | 0.500 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
23 |
MTA2 | interactor | 3 | 0.667 | 0.500 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
24 |
NXF1 | interactor | 9 | 0.357 | 14.833 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
25 |
PBDC1 | interactor | 1 | 0 | 0 | Polysacc_synt_4 (PF04669, IPR021148): Polysaccharide biosynthesis |
26 |
POLR2A | protein found in more fusions | 15 | 0.341 | 48.500 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
27 |
SART3 | protein found in more fusions | 3 | 1.000 | 0 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993) Lsm_interact (PF05391, IPR008669): Lsm interaction motif Phage_GPD (PF05954): Phage late control gene D protein (GPD) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat MRI (PF15325, IPR028278): Modulator of retrovirus infection LSM_int_assoc (PF16605): LSM-interacting associated unstructured |
28 |
SEC24D | interactor | 2 | 1.000 | 0 | Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain Transp_Tc5_C (PF04236, IPR007350): Tc5 transposase C-terminal domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger |
29 |
SHMT2 | interactor | 4 | 0.500 | 2.500 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
30 |
SIN3A | oncoprotein | 4 | 0.500 | 1.833 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
31 |
SND1 | interactor | 5 | 0.700 | 1.667 | TUDOR (PF00567, IPR002999, SM00333): Tudor domain SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue |
32 |
TBP | interactor | 13 | 0.500 | 22.267 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
33 |
TPR | oncoprotein | 4 | 0.500 | 2.667 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
34 |
UBR5 | protein found in more fusions | 3 | 1.000 | 0 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
35 |
XPA | oncoprotein | 2 | 1.000 | 0 | XPA_C (PF05181, IPR022656): XPA protein C-terminus XPA_N (PF01286, IPR022652): XPA protein N-terminal MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain |