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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins GPX3 (from a repository: Thu Nov 10 14:59:26 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)3
The number (and %) of the onco-proteins1 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)4 (133.33 %)
The number (and %) of affected PPIs3 (75.00 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI1.333
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients3 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (66.67 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: GPX3 All fusions
: W25873; BF878552; BG896291; BG430541; BG927502;
Proteins found in more fusions GPX3 (see 5 fusions); UBQLN1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 GPX3parental protein302.000GSHPx (PF00255, IPR000889): Glutathione peroxidase
2 TP53I3interactor100ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
HupF_HypC (PF01455, IPR001109): HupF/HypC family
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
3 UBQLN1protein found in more fusions200Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X

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