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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins GNPNAT1 (from a repository: Thu Nov 17 03:21:01 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins5 (45.45 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)20 (36.36 %)
The number (and %) of affected PPIs11 (55.00 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI2.727
Assortativity coefficient-0.3984
The network average Clustering coefficient0.571
The number (and %) of a zero Clustering coefficients3 (27.27 %)
The number (and %) of a zero Betweenness Centrality8 (72.73 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: GNPNAT1 All fusions
Proteins found in more fusions PCBP2 (see 3 fusions); MCM2 (see 1 fusions); NAGK (see 1 fusions); GNPNAT1 (see 1 fusions); UBE2N (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 GNPNAT1parental protein110.11176.000Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
2 ADSSinteractor100Adenylsucc_synt (PF00709, IPR001114, SM00788): Adenylosuccinate synthetase
3 ASPDHinteractor21.0000DUF108 (PF01958, IPR002811): Domain of unknown function DUF108
NAD_binding_3 (PF03447, IPR005106): Homoserine dehydrogenase, NAD binding domain
4 C1QAoncoprotein100C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
5 FHsuppressor40.5003.000Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
6 GPD1interactor21.0000NAD_Gly3P_dh_C (PF07479, IPR006109): NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
7 GPD1Linteractor21.0000NAD_Gly3P_dh_C (PF07479, IPR006109): NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
8 MCM2oncoprotein31.0000AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
9 NAGKprotein found in more fusions200BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
10 PCBP2protein found in more fusions31.0000Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
11 UBE2Nprotein found in more fusions40.6671.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme

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