1 |
GFAP | parental protein | 58 | 0.068 | 2549.600 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
2 |
AES | protein found in more fusions | 11 | 0.356 | 24.300 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain |
3 |
AKT1 | oncoprotein | 10 | 0.444 | 15.233 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
4 |
ALB | protein found in more fusions | 6 | 0.400 | 8.333 | Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family |
5 |
ALG3 | interactor | 1 | 0 | 0 | ALG3 (PF05208, IPR007873): ALG3 protein CBP_BcsF (PF11120, IPR019995): Cellulose biosynthesis protein BcsF |
6 |
AP2M1 | protein found in more fusions | 5 | 0.667 | 1.667 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
7 |
APP | protein found in more fusions | 15 | 0.231 | 62.067 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
AURKB | interactor | 6 | 0.700 | 1.500 | Pkinase (PF00069, IPR000719): Protein kinase domain |
9 |
BIRC2 | oncoprotein | 3 | 1.000 | 0 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
10 |
CDC37 | protein found in more fusions | 12 | 0.400 | 24.333 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
11 |
CEBPA | suppressor | 3 | 1.000 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
12 |
CEP76 | interactor | 3 | 0.667 | 1.000 | Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily CEP76-C2 (PF15627, IPR028926): CEP76 C2 domain |
13 |
CFAP206 | interactor | 3 | 1.000 | 0 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 DUF3508 (PF12018, IPR021897): Domain of unknown function (DUF3508) |
14 |
CRYAB | oncoprotein | 4 | 1.000 | 0 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
15 |
DNASE1L1 | interactor | 1 | 0 | 0 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family |
16 |
ERBB3 | oncoprotein | 7 | 0.733 | 1.900 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
17 |
ERRFI1 | suppressor | 6 | 0.900 | 0.400 | GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 |
18 |
ESRRB | suppressor | 6 | 0.733 | 2.400 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
19 |
FAM50B | interactor | 2 | 1.000 | 0 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator |
20 |
FBXO25 | suppressor | 4 | 0.500 | 2.067 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
21 |
GOLGA2 | interactor | 8 | 0.286 | 16.733 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
22 |
GRAP2 | interactor | 2 | 1.000 | 0 | NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
23 |
GRB2 | oncoprotein | 16 | 0.295 | 63.933 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
24 |
HGS | interactor | 6 | 0.533 | 5.500 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
25 |
HSPA5 | oncoprotein | 15 | 0.308 | 50.700 | HSP70 (PF00012, IPR013126): Hsp70 protein |
26 |
IKBKG | interactor | 5 | 0.667 | 2.000 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
27 |
KIAA0408 | interactor | 3 | 0.667 | 0.400 | IncA (PF04156, IPR007285): IncA protein DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482) |
28 |
KRT13 | interactor | 5 | 0.400 | 4.733 | Filament (PF00038, IPR001664): Intermediate filament protein FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus Keratin_2_head (PF16208, IPR032444): Keratin type II head |
29 |
KRT15 | interactor | 10 | 0.311 | 24.300 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
30 |
LGALS14 | interactor | 2 | 1.000 | 0 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin |
31 |
LMO2 | oncoprotein | 7 | 0.600 | 5.067 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal LIM (PF00412, IPR001781, SM00132): LIM domain |
32 |
MEN1 | suppressor | 2 | 1.000 | 0 | Menin (PF05053, IPR007747): Menin |
33 |
MOS | oncoprotein | 5 | 0.400 | 3.133 | Pkinase (PF00069, IPR000719): Protein kinase domain |
34 |
MYO15B | interactor | 2 | 1.000 | 0 | FERM_M (PF00373, IPR019748): FERM central domain MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) SH3_9 (PF14604, IPR001452): Variant SH3 domain BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3 |
35 |
NT5DC1 | interactor | 1 | 0 | 0 | 5_nucleotid (PF05761, IPR008380): 5' nucleotidase family |
36 |
NXF1 | interactor | 8 | 0.381 | 10.900 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
37 |
P2RY8 | oncoprotein | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
38 |
PDCD6IP | interactor | 3 | 1.000 | 0 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
39 |
PDLIM1 | interactor | 4 | 0.667 | 1.000 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
40 |
PDLIM7 | interactor | 3 | 0.667 | 0.667 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
41 |
PDZK1 | interactor | 4 | 1.000 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265) |
42 |
PIAS2 | protein found in more fusions | 5 | 0.500 | 2.400 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
43 |
PIH1D2 | interactor | 2 | 0 | 0 | PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17 |
44 |
POM121 | interactor | 3 | 0.667 | 1.000 | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region POM121 (PF15229): POM121 family |
45 |
PRKCG | interactor | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
46 |
PSEN1 | oncoprotein | 5 | 0.833 | 0.667 | Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain |
47 |
PSEN2 | oncoprotein | 4 | 1.000 | 0 | Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin |
48 |
RIBC2 | interactor | 3 | 0.667 | 0.400 | RIB43A (PF05914, IPR008805): RIB43A |
49 |
RORA | interactor | 1 | 0 | 0 | zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
50 |
SH3YL1 | interactor | 2 | 1.000 | 0 | Ysc84 (PF04366, IPR007461): Las17-binding protein actin regulator SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
51 |
SHC1 | oncoprotein | 11 | 0.400 | 19.400 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
52 |
STAT1 | suppressor | 3 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
53 |
TRIM27 | oncoprotein | 9 | 0.286 | 15.133 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
54 |
TUBGCP4 | interactor | 6 | 0.333 | 5.933 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family |
55 |
UBASH3B | interactor | 8 | 0.714 | 3.467 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
56 |
UBE3A | oncoprotein | 5 | 0.500 | 2.333 | HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A |
57 |
VIM | suppressor | 12 | 0.200 | 39.067 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
58 |
ZC2HC1C | interactor | 3 | 0.667 | 0.333 | zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type |