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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)143
The number (and %) of the onco-proteins42 (29.37 %)
The number (and %) of the tumor suppressors19 (13.29 %)
Total number of binary PPIs (saturation %)1056 (10.40 %)
The number (and %) of affected PPIs157 (14.87 %)
The number of possible different fusions25
PPI diameter3
PPI radius2
The average degree of PPI14.000
Assortativity coefficient-0.1768
The network average Clustering coefficient0.390
The number (and %) of a zero Clustering coefficients12 (8.39 %)
The number (and %) of a zero Betweenness Centrality13 (9.09 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions FUBP1/FUBP3 (see 1 fusions); U2AF2 (see 2 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); CCDC88A (see 3 fusions); XBP1 (see 2 fusions); AIMP2 (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); SMARCC1 (see 2 fusions); RPA1 (see 1 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); ATXN1 (see 3 fusions); PDCD6 (see 1 fusions); HNRNPD (see 1 fusions); PCBP2 (see 3 fusions); CSRP1 (see 3 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); NQO1 (see 2 fusions); CHD3 (see 1 fusions); QKI (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 FUBP3parental protein600.1323753.380DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
2 FUBP1parental protein980.0967209.439DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
3 AARSD1interactor80.6795.529tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
4 ABCE1interactor120.29129.934ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
5 ACO1interactor40.3332.419Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
6 ACTR2interactor210.42968.454Actin (PF00022, IPR004000, SM00268): Actin
7 ACTR3interactor160.49229.141Actin (PF00022, IPR004000, SM00268): Actin
8 AIMP2suppressor100.38926.005GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
9 ANXA11interactor90.41715.794Annexin (PF00191, IPR018502, SM00335): Annexin
10 ANXA2interactor250.363100.903Annexin (PF00191, IPR018502, SM00335): Annexin
11 APPprotein found in more fusions330.181464.061APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
12 ARF4interactor120.53021.778Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
13 ARPC2interactor150.48629.173P34-Arc (PF04045, IPR007188): Arp2/3 complex, 34 kD subunit p34-Arc
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
14 ARPC4interactor160.50039.221ARPC4 (PF05856, IPR008384): ARP2/3 complex 20 kDa subunit (ARPC4)
15 ATF2oncoprotein120.34531.335bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
16 ATP1B1interactor60.40026.361Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
17 ATXN1protein found in more fusions60.20027.790AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
18 B9D2interactor21.0000B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
19 BAG1oncoprotein100.55632.976BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
20 CAND1interactor300.392175.247Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
21 CAPGsuppressor70.23865.825Gelsolin (PF00626, IPR007123): Gelsolin repeat
22 CCDC58interactor51.0000Cid2 (PF09774, IPR019171): Caffeine-induced death protein 2
23 CCDC88Aprotein found in more fusions60.20017.131bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
24 CCNHoncoprotein70.5716.0945_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
25 CD81interactor160.33341.191Tetraspannin (PF00335, IPR018499): Tetraspanin family
26 CDK18oncoprotein30.6674.796APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
27 CDK2suppressor260.370142.862Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
28 CELF1interactor90.41739.116RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
29 CEP170P1interactor50.5002.221NA
30 CERS2interactor100PDR_CDR (PF06422, IPR010929): CDR ABC transporter
TRAM1 (PF08390, IPR013599): TRAM1-like protein
TRAM_LAG1_CLN8 (PF03798, IPR006634): TLC domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
31 CHD3oncoprotein100.44411.665CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
32 CHORDC1interactor60.5005.890CHORD (PF04968, IPR007051): CHORD
CS (PF04969, IPR007052): CS domain
33 CNN2interactor60.5333.060Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
34 COPS5protein found in more fusions270.46582.517JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
35 CRIP1interactor80.35715.141LIM (PF00412, IPR001781, SM00132): LIM domain
36 CRKoncoprotein30.33316.448SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
37 CRMP1interactor60.30015.438Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
38 CSRP1protein found in more fusions60.6004.135LIM (PF00412, IPR001781, SM00132): LIM domain
zf-MYND (PF01753, IPR002893): MYND finger
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
39 CTSDinteractor40.3338.430A1_Propeptide (PF07966, IPR012848): A1 Propeptide
Asp (PF00026, IPR001461): Eukaryotic aspartyl protease
40 CUL3protein found in more fusions400.262430.130Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
41 CUL7protein found in more fusions290.378164.463ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
42 DAZAP1interactor260.314179.644RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
43 DDX19Ainteractor60.40024.056DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
44 DHX36interactor110.54511.009DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45 DPP8interactor200.612DPPIV_N (PF00930, IPR002469): Dipeptidyl peptidase IV (DPP IV) N-terminal region
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
46 DUTinteractor140.33061.558dUTPase (PF00692, IPR008180): dUTPase
47 EEDsuppressor210.47461.698WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
48 ELAVL1oncoprotein500.235905.074RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
49 ESR1suppressor260.237243.303Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
50 FN1oncoprotein370.290402.829fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
51 FOXA3interactor60.33335.497CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
HNF_C (PF09354, IPR018533): HNF3 C-terminal domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
52 FOXB1interactor60.26731.458Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
53 FOXE1oncoprotein100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
54 FOXF1interactor31.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
55 FOXL2suppressor200.612K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
56 FOXP3suppressor21.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
57 FOXQ1interactor100Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
58 FOXS1interactor30.3337.131Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
59 FSCN1oncoprotein120.42420.305Fascin (PF06268, IPR022768): Fascin domain
60 GDI1interactor70.19024.745GDI (PF00996, IPR018203): GDP dissociation inhibitor
61 GRPEL1interactor120.52717.102GrpE (PF01025, IPR000740): GrpE
62 GTF2H1oncoprotein50.7001.886BSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
63 HIST1H2BOinteractor50.40013.670Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
64 HNRNPA1interactor470.276644.328RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
65 HNRNPDoncoprotein300.39996.837CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
66 ISG15suppressor90.13923.096ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
67 ITGA4interactor270.391137.311FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
68 ITGA5suppressor21.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
69 KHSRPinteractor310.318305.787DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
70 KIF21Binteractor208.146CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
Thioredoxin_4 (PF13462, IPR012336): Thioredoxin
BORG_CEP (PF14957, IPR029273): Cdc42 effector
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
71 KYNUinteractor40.3335.221Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit
72 LAP3interactor110.34543.688Peptidase_M17 (PF00883, IPR000819): Cytosol aminopeptidase family, catalytic domain
Peptidase_M17_N (PF02789, IPR008283): Cytosol aminopeptidase family, N-terminal domain
PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW
73 LATS2suppressor80.33312.852Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
74 LGALS1interactor170.33869.339Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
75 MAELinteractor40.6671.267HMG_box_2 (PF09011, IPR009071): HMG-box domain
Maelstrom (PF13017, IPR024970): piRNA pathway germ-plasm component
76 MATR3interactor240.403120.782DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
77 MCM2oncoprotein420.293545.897AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
78 MDM2oncoprotein150.36360.145Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
79 MRPL2interactor40.6672.155Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
80 MRPL32interactor50.4009.759Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family
81 MRPL38interactor60.26758.645PBP (PF01161, IPR008914): Phosphatidylethanolamine-binding protein
DUF3095 (PF11294, IPR021445): Protein of unknown function (DUF3095)
82 MRPL41interactor30.3333.868MRP-L27 (PF09809, IPR019189): Mitochondrial ribosomal protein L27
83 MRPL42interactor30.6671.000MRP-S32 (PF10210, IPR019346): Mitochondrial 28S ribosomal protein S32
84 MRPL46interactor200.338NUDIX (PF00293, IPR000086): NUDIX domain
MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46
85 MYOCinteractor70.6001.630IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
86 NDUFS4interactor40.6673.466ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
87 NIF3L1interactor160.43844.652NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3)
88 NME1suppressor70.26725.064NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
89 NQO1oncoprotein60.60012.927Flavodoxin_2 (PF02525, IPR003680): Flavodoxin-like fold
90 NSUN2interactor130.44920.156Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
91 NTRK1oncoprotein510.209966.955I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
92 NUP62interactor60.30010.967Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
93 OBSL1interactor250.41797.977BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
94 PARK2suppressor150.28649.599IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
95 PAX9oncoprotein206.638PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
96 PCBP1oncoprotein360.381275.870Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
97 PCBP2protein found in more fusions270.50583.367Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
98 PDCD6oncoprotein110.6895.433EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
99 PGM1interactor30.3331.344PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
100 PIRinteractor50.5005.878Pirin (PF02678, IPR003829): Pirin
Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain
101 PKMoncoprotein260.342151.537PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
102 PLD3interactor40.6670.691PLDc_2 (PF13091, IPR025202): PLD-like domain
PLDc_3 (PF13918, IPR032803): PLD-like domain
103 PPICinteractor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
104 PPP5Cinteractor90.33359.313Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PPP5 (PF08321, IPR013235): PPP5 TPR repeat region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
105 PRDX2interactor220.40389.771AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
106 PRDX5interactor90.33330.455Redoxin (PF08534, IPR013740): Redoxin
NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding
107 QKIprotein found in more fusions100.55615.712KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
108 RAB10oncoprotein130.41027.575Ras (PF00071, IPR001806, SM00173): Ras family
109 RAB1Aoncoprotein110.40033.596Ras (PF00071, IPR001806, SM00173): Ras family
110 RAB32oncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
111 RACK1suppressor300.384161.296WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
112 RHOAsuppressor60.26715.843Ras (PF00071, IPR001806, SM00173): Ras family
113 RNF2interactor280.265191.616zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
114 RPA1suppressor360.321326.372Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
115 RPA2oncoprotein270.276284.762RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
116 RPA3interactor270.277273.576Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
117 RPRD1Binteractor130.46237.302CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
118 RPS15interactor120.42426.139Ribosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
119 SAV1oncoprotein60.40018.078WW (PF00397, IPR001202, SM00456): WW domain
120 SEC16Ainteractor110.45524.325APC_r (PF05923): APC repeat
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
121 SH3GL1oncoprotein130.60610.801BAR (PF03114, IPR004148, SM00721): BAR domain
PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
122 SIN3Aoncoprotein140.36352.135Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
123 SIRT7interactor240.199163.625DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
124 SMARCA2suppressor100.55611.439DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
125 SMARCAD1interactor110.49125.915CUE (PF02845, IPR003892, SM00546): CUE domain
Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
126 SMARCC1suppressor150.56033.121SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
127 SMARCC2interactor190.368103.576GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
128 SMN1interactor110.40021.504SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
129 SNCGoncoprotein100Synuclein (PF01387, IPR001058): Synuclein
130 SNW1protein found in more fusions270.378138.857SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
131 SPRinteractor60.5338.062adh_short (PF00106, IPR002198): short chain dehydrogenase
132 SRRM1interactor120.6826.803DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
133 SRSF3oncoprotein230.41160.852DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
134 SSX1oncoprotein100KRAB (PF01352, IPR001909, SM00349): KRAB box
SSXRD (PF09514, IPR019041): SSXRD motif
135 SUZ12suppressor150.45132.655DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
136 TARDBPinteractor290.46884.377RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
137 TLE1interactor80.19089.459TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
138 TOMM40interactor70.19053.570Porin_3 (PF01459, IPR027246): Eukaryotic porin
139 U2AF2protein found in more fusions360.363281.089RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
140 USP22interactor100UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
DUF2769 (PF10967, IPR020075): Protein of unknown function (DUF2769)
141 VCAM1interactor210.44358.096C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
142 VIMsuppressor230.251122.997Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
143 XBP1protein found in more fusions40.3333.036DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630)

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