1 |
FOS | parental protein | 130 | 0.053 | 12361.493 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
2 |
ABL1 | oncoprotein | 7 | 0.467 | 4.176 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
AHCY | interactor | 4 | 0.667 | 0.250 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
4 |
ANKHD1 | interactor | 1 | 0 | 0 | DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein KH_1 (PF00013, IPR004088, SM00322): KH domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) AAA_23 (PF13476): AAA domain DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
5 |
ANKRD17 | interactor | 1 | 0 | 0 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein Mucin (PF01456, IPR000458): Mucin-like glycoprotein DUF2536 (PF10750, IPR019686): Protein of unknown function (DUF2536) KH_1 (PF00013, IPR004088, SM00322): KH domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 |
6 |
ANP32E | interactor | 1 | 0 | 0 | BUD22 (PF09073, IPR015158): BUD22 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_9 (PF14580): Leucine-rich repeat |
7 |
APP | protein found in more fusions | 23 | 0.160 | 164.330 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
AQP1 | interactor | 2 | 0 | 0 | MIP (PF00230, IPR000425): Major intrinsic protein |
9 |
ARFGAP1 | interactor | 2 | 1.000 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
10 |
ARL6IP4 | interactor | 3 | 1.000 | 0 | SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
11 |
ATF2 | oncoprotein | 25 | 0.362 | 90.688 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
12 |
ATF3 | suppressor | 20 | 0.462 | 42.315 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
13 |
ATF4 | oncoprotein | 19 | 0.444 | 43.984 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
14 |
ATF7 | interactor | 3 | 1.000 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
15 |
ATP5I | interactor | 1 | 0 | 0 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain |
16 |
BCL3 | oncoprotein | 7 | 0.857 | 0.869 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
17 |
CABP1 | interactor | 1 | 0 | 0 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
18 |
CARM1 | oncoprotein | 11 | 0.545 | 10.905 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
19 |
CEBPA | suppressor | 17 | 0.467 | 28.075 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
20 |
CEBPE | interactor | 12 | 0.564 | 12.471 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
21 |
CEBPG | interactor | 9 | 0.929 | 0.472 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 |
22 |
CENPO | interactor | 1 | 0 | 0 | CENP-O (PF09496, IPR018464): Cenp-O kinetochore centromere component Takusan (PF04822, IPR006907): Takusan MnmE_helical (PF12631, IPR025867): MnmE helical domain |
23 |
CHEK2 | suppressor | 7 | 0.600 | 1.958 | FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain |
24 |
CLU | suppressor | 5 | 0.833 | 0.400 | Clusterin (PF01093, IPR000753): Clusterin |
25 |
COPS4 | interactor | 3 | 0.667 | 0.667 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat |
26 |
CREB5 | interactor | 6 | 0.700 | 1.533 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Zip (PF02535, IPR003689): ZIP Zinc transporter Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator |
27 |
CREBBP | suppressor | 36 | 0.304 | 206.898 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
28 |
CSNK2A1 | oncoprotein | 21 | 0.279 | 97.302 | Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CYTH4 | interactor | 1 | 0 | 0 | MazG (PF03819, IPR004518): MazG nucleotide pyrophosphohydrolase domain PH (PF00169, IPR001849, SM00233): PH domain Sec7 (PF01369, IPR000904, SM00222): Sec7 domain |
30 |
DDIT3 | oncoprotein | 16 | 0.524 | 22.794 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
31 |
DDX17 | protein found in more fusions | 8 | 0.571 | 2.760 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
32 |
DET1 | interactor | 3 | 1.000 | 0 | Det1 (PF09737, IPR019138): De-etiolated protein 1 Det1 |
33 |
DNMT3L | interactor | 11 | 0.618 | 6.285 | CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain |
34 |
EEF1D | protein found in more fusions | 9 | 0.536 | 9.467 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
35 |
EGFR | oncoprotein | 12 | 0.273 | 25.944 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
36 |
EP300 | oncoprotein | 39 | 0.263 | 286.410 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
37 |
ESR1 | suppressor | 31 | 0.251 | 221.393 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
38 |
ETS2 | suppressor | 10 | 0.467 | 15.217 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
39 |
FAAP100 | interactor | 2 | 1.000 | 0 | FANCAA (PF15146, IPR029251): Fanconi anemia-associated |
40 |
FNBP1L | interactor | 1 | 0 | 0 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat DEDD_Tnp_IS110 (PF01548, IPR002525): Transposase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain GTP-bdg_M (PF16360, IPR032305): GTP-binding GTPase Middle Region |
41 |
FOSB | oncoprotein | 6 | 0.600 | 1.425 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin |
42 |
GAMT | interactor | 1 | 0 | 0 | Methyltransf_25 (PF13649): Methyltransferase domain |
43 |
GLB1 | oncoprotein | 1 | 0 | 0 | Glyco_hydro_35 (PF01301, IPR001944): Glycosyl hydrolases family 35 BetaGal_dom4_5 (PF13364, IPR025300): Beta-galactosidase jelly roll domain |
44 |
GLO1 | interactor | 2 | 1.000 | 0 | Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily |
45 |
GNG11 | interactor | 1 | 0 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
46 |
GRHPR | interactor | 3 | 0.667 | 1.000 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
47 |
GTF2E2 | protein found in more fusions | 7 | 0.800 | 1.300 | TFIIE_beta (PF02186, IPR003166): TFIIE beta subunit core domain VCX_VCY (PF15231, IPR026653): Variable charge X/Y family |
48 |
GTF2F1 | interactor | 9 | 0.583 | 8.019 | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) |
49 |
GTF2F2 | interactor | 7 | 0.667 | 5.067 | TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit |
50 |
HNF1A | oncoprotein | 7 | 0.800 | 0.867 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
51 |
HOXD13 | oncoprotein | 4 | 0.833 | 0.250 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal |
52 |
HSD17B4 | interactor | 2 | 1.000 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase |
53 |
HSPA1A | interactor | 3 | 0.667 | 0.333 | HSP70 (PF00012, IPR013126): Hsp70 protein |
54 |
JUN | oncoprotein | 61 | 0.164 | 1091.940 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
55 |
JUNB | oncoprotein | 12 | 0.424 | 20.958 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
56 |
JUND | oncoprotein | 12 | 0.455 | 16.026 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
57 |
KBTBD7 | interactor | 1 | 0 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_2 (PF07646, IPR011498): Kelch motif Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif |
58 |
KDM2A | interactor | 4 | 0.667 | 0.422 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain F-box (PF00646, IPR001810, SM00256): F-box domain DZR (PF12773, IPR025874): Double zinc ribbon LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat PHD_4 (PF16866, IPR019787): PHD-finger |
59 |
KDM2B | oncoprotein | 5 | 0.667 | 1.333 | zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain F-box (PF00646, IPR001810, SM00256): F-box domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat Cupin_8 (PF13621): Cupin-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat MRI (PF15325, IPR028278): Modulator of retrovirus infection PHD_4 (PF16866, IPR019787): PHD-finger |
60 |
KHSRP | interactor | 4 | 1.000 | 0 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
61 |
LMO3 | oncoprotein | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain |
62 |
LUZP4 | interactor | 4 | 0.667 | 1.000 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) |
63 |
MAF | oncoprotein | 10 | 0.500 | 9.617 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein Metal_resist (PF13801, IPR025961): Heavy-metal resistance |
64 |
MAFB | oncoprotein | 5 | 0.667 | 0.650 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region |
65 |
MAFF | interactor | 4 | 1.000 | 0 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
66 |
MAP1B | interactor | 2 | 1.000 | 0 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) MAP1B_neuraxin (PF00414, IPR000102): Neuraxin and MAP1B repeat Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup Striatin (PF08232, IPR013258): Striatin family IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
67 |
MAPK1 | oncoprotein | 15 | 0.505 | 26.338 | Pkinase (PF00069, IPR000719): Protein kinase domain |
68 |
MAPK7 | oncoprotein | 4 | 0.667 | 0.222 | Pkinase (PF00069, IPR000719): Protein kinase domain Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor |
69 |
MAPK9 | suppressor | 9 | 0.357 | 12.845 | Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like |
70 |
MAZ | interactor | 3 | 1.000 | 0 | zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF2057 (PF09829, IPR018635): Uncharacterized protein conserved in bacteria (DUF2057) zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597) DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
71 |
MED17 | oncoprotein | 2 | 1.000 | 0 | Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex |
72 |
MITF | oncoprotein | 5 | 0.600 | 1.341 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
73 |
MTERF4 | interactor | 2 | 1.000 | 0 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein mTERF (PF02536, IPR003690, SM00733): mTERF |
74 |
MTMR1 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein Myb_CC_LHEQLE (PF14379, IPR025756): MYB-CC type transfactor, LHEQLE motif |
75 |
NACA | oncoprotein | 3 | 1.000 | 0 | NAC (PF01849, IPR002715): NAC domain RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain CitT (PF12431, IPR028141): Transcriptional regulator |
76 |
NCOA1 | oncoprotein | 20 | 0.456 | 49.186 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
77 |
NCOA2 | oncoprotein | 11 | 0.655 | 7.488 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
78 |
NCOA3 | oncoprotein | 18 | 0.451 | 41.226 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
79 |
NCOA6 | oncoprotein | 17 | 0.600 | 20.266 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
80 |
NCOR2 | oncoprotein | 12 | 0.727 | 4.183 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
81 |
NEFM | interactor | 2 | 1.000 | 0 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637) |
82 |
NELFB | protein found in more fusions | 5 | 0.833 | 0.400 | COBRA1 (PF06209, IPR010405): Cofactor of BRCA1 (COBRA1) |
83 |
NFATC1 | oncoprotein | 10 | 0.578 | 7.827 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
84 |
NFATC2IP | interactor | 1 | 0 | 0 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
85 |
NFIX | oncoprotein | 4 | 1.000 | 0 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
86 |
NQO1 | oncoprotein | 2 | 0 | 0 | Flavodoxin_2 (PF02525, IPR003680): Flavodoxin-like fold |
87 |
NR2F1 | oncoprotein | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
88 |
NR2F6 | oncoprotein | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
89 |
PML | suppressor | 24 | 0.320 | 93.141 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
90 |
POLR2E | protein found in more fusions | 5 | 0.500 | 1.333 | RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain |
91 |
PPP1R12A | interactor | 2 | 1.000 | 0 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) Mucin (PF01456, IPR000458): Mucin-like glycoprotein RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050) AAA_23 (PF13476): AAA domain Ank_5 (PF13857): Ankyrin repeats (many copies) GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
92 |
PRKAA2 | suppressor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase |
93 |
PSMC5 | protein found in more fusions | 6 | 0.900 | 0.143 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
94 |
RB1 | suppressor | 20 | 0.337 | 76.456 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
95 |
RELA | oncoprotein | 25 | 0.322 | 113.320 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
96 |
RFWD2 | suppressor | 11 | 0.289 | 26.468 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain |
97 |
RPS6KA2 | suppressor | 5 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
98 |
RPS6KA4 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
99 |
RUNX1 | suppressor | 11 | 0.689 | 5.253 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
100 |
RUNX2 | suppressor | 7 | 0.857 | 0.518 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
101 |
SET | oncoprotein | 5 | 0.500 | 1.119 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
102 |
SIRT1 | suppressor | 15 | 0.440 | 25.790 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
103 |
SMAD3 | oncoprotein | 25 | 0.402 | 75.764 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
104 |
SMARCC1 | suppressor | 10 | 0.639 | 6.091 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
105 |
SMARCC2 | interactor | 10 | 0.467 | 12.825 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
106 |
SMARCE1 | interactor | 7 | 0.762 | 1.578 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
107 |
SPI1 | suppressor | 10 | 0.467 | 11.162 | Ets (PF00178, IPR000418, SM00413): Ets-domain p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain |
108 |
SRA1 | interactor | 9 | 0.500 | 6.423 | SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) |
109 |
SSU72 | interactor | 2 | 1.000 | 0 | Ssu72 (PF04722, IPR006811): Ssu72-like protein |
110 |
STAT1 | suppressor | 12 | 0.600 | 8.987 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
111 |
STK40 | interactor | 4 | 0.667 | 1.667 | Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like |
112 |
TAF1 | oncoprotein | 8 | 0.714 | 2.431 | Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit LcrG (PF07216, IPR009863): LcrG protein Opi1 (PF08618, IPR013927): Transcription factor Opi1 Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal TBP-binding (PF09247, IPR009067): TATA box-binding protein binding U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591) zf-CCHC_6 (PF15288): Zinc knuckle |
113 |
TBP | interactor | 18 | 0.478 | 33.678 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
114 |
TCL1A | oncoprotein | 5 | 0.833 | 0.182 | TCL1_MTCP1 (PF01840, IPR004832): TCL1/MTCP1 family |
115 |
TRAPPC13 | interactor | 1 | 0 | 0 | DUF974 (PF06159, IPR010378): Protein of unknown function (DUF974) Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Trs65 (PF12735, IPR024662): TRAPP trafficking subunit Trs65 |
116 |
TRIB1 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
117 |
TSC22D3 | protein found in more fusions | 4 | 1.000 | 0 | TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
118 |
TSPAN2 | interactor | 1 | 0 | 0 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
119 |
UBE2D1 | interactor | 8 | 0.429 | 9.067 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
120 |
UBE2I | interactor | 24 | 0.328 | 99.783 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
121 |
UBE2L3 | interactor | 4 | 0.667 | 0.182 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
122 |
UBR1 | interactor | 2 | 1.000 | 0 | ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
123 |
USF1 | oncoprotein | 5 | 0.667 | 1.222 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
124 |
USF2 | protein found in more fusions | 6 | 0.700 | 1.733 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
125 |
UTP4 | interactor | 2 | 1.000 | 0 | CPSF_A (PF03178, IPR004871): CPSF A subunit region PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 (PF13360, IPR002372): PQQ-like domain |
126 |
VARS | interactor | 4 | 0.667 | 0.722 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C (PF10458, IPR019499): Valyl tRNA synthetase tRNA binding arm SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
127 |
VDR | suppressor | 18 | 0.522 | 22.377 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
128 |
XBP1 | protein found in more fusions | 4 | 1.000 | 0 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630) |
129 |
YEATS4 | interactor | 1 | 0 | 0 | YEATS (PF03366, IPR005033): YEATS family SOGA (PF11365, IPR027881): Protein SOGA |
130 |
ZNF133 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |