Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins FKBP8 (from a repository: Fri Dec 2 02:33:52 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 87 The number (and %) of the onco-proteins 21 (24.14 %) The number (and %) of the tumor suppressors 4 (4.60 %) Total number of binary PPIs (saturation %) 691 (18.47 %) The number (and %) of affected PPIs 87 (12.59 %) The number of possible different fusions 17 PPI diameter 2 PPI radius 1 The average degree of PPI 15.149 Assortativity coefficient -0.1077 The network average Clustering coefficient 0.702 The number (and %) of a zero Clustering coefficients 4 (4.60 %) The number (and %) of a zero Betweenness Centrality 19 (21.84 %)

ACTIVE INTERACTORS MISSING INTERACTORS (in fusions)

List of the fusions
PPI for parental proteins: FKBP8	All fusions : L37033;
Proteins found in more fusions	PSMC2 (see 1 fusions); ABCC1 (see 1 fusions); HSP90AA1 (see 2 fusions); CUL3 (see 1 fusions); PSMB3 (see 1 fusions); VHL (see 1 fusions); PSMB7 (see 2 fusions); FKBP8 (see 1 fusions); BCL2L1 (see 1 fusions); EGFR (see 2 fusions); PSMA7 (see 2 fusions); UBC (see 1 fusions); MTOR (see 1 fusions); RPTOR (see 3 fusions); PSMC5 (see 2 fusions); EGLN1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	FKBP8	parental protein	87	0.157	4998.408	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
2	ABCB7	interactor	3	0.667	0.667	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain AAA_23 (PF13476): AAA domain
3	ABCC1	oncoprotein	6	0.600	3.667	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304) DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
4	ADRB2	interactor	9	0.393	9.855	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
5	ADRM1	interactor	31	0.935	7.353	Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor GET2 (PF08690, IPR028143): GET complex subunit GET2 RPN13_C (PF16550, IPR032368): UCH-binding domain
6	ARHGEF5	interactor	2	1.000	0	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_9 (PF14604, IPR001452): Variant SH3 domain ARHGEF5_35 (PF15441, IPR029212): Rho guanine nucleotide exchange factor 5/35
7	ATP13A2	interactor	1	0	0	E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase MARVEL (PF01284, IPR008253): Membrane-associating domain P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter
8	ATP6AP2	interactor	6	0.400	5.333	Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r (PF07850, IPR012493): Renin receptor-like protein
9	BCL2	oncoprotein	5	0.667	2.000	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
10	BCL2L1	oncoprotein	5	0.667	2.000	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
11	BNIPL	interactor	4	1.000	0	BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
12	BRE	oncoprotein	2	1.000	0	BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
13	CACYBP	interactor	5	0.833	0.667	CS (PF04969, IPR007052): CS domain SGS (PF05002, IPR007699): SGS domain Siah-Interact_N (PF09032, IPR015120): Siah interacting protein, N terminal
14	CALM1	interactor	8	0.607	3.428	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
15	CAMK2A	interactor	4	0.667	0.286	CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain Pkinase (PF00069, IPR000719): Protein kinase domain
16	CCDC8	interactor	10	0.472	12.268	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
17	CDK20	oncoprotein	5	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
18	CLN3	interactor	2	1.000	0	CLN3 (PF02487, IPR003492): CLN3 protein
19	COQ9	interactor	6	0.500	4.333	COQ9 (PF08511, IPR013718): COQ9
20	CUL3	protein found in more fusions	16	0.505	37.186	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
21	DHODH	interactor	1	0	0	DHO_dh (PF01180, IPR012135): Dihydroorotate dehydrogenase FMN_dh (PF01070, IPR000262): FMN-dependent dehydrogenase PASTA (PF03793, IPR005543, SM00740): PASTA domain
22	EGFR	oncoprotein	17	0.308	65.534	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
23	EGLN1	suppressor	3	1.000	0	zf-MYND (PF01753, IPR002893): MYND finger 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
24	EVC2	interactor	4	0.500	3.000	HBS1_N (PF08938, IPR015033): HBS1 N-terminus DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) Histone_HNS (PF00816, IPR001801): H-NS histone family EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
25	HSP90AA1	oncoprotein	19	0.203	95.892	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
26	HSPBP1	interactor	2	1.000	0	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like HEAT_EZ (PF13513): HEAT-like repeat
27	KCNH2	interactor	2	1.000	0	Ion_trans (PF00520, IPR005821): Ion transport protein cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain PAS_9 (PF13426, IPR000014): PAS domain
28	MLH1	suppressor	4	0.833	0.080	DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
29	MLST8	interactor	4	1.000	0	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
30	MRPL11	interactor	3	0.667	1.000	Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
31	MRPL15	interactor	2	1.000	0	Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
32	MTOR	oncoprotein	9	0.393	15.833	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
33	NDUFB10	interactor	1	0	0	NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
34	NNT	interactor	3	0.667	0.667	AlaDh_PNT_C (PF01262, IPR007698, SM01002): Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N (PF05222, IPR007886, SM01003): Alanine dehydrogenase/PNT, N-terminal domain PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit PNTB_4TM (PF12769, IPR024605): 4TM region of pyridine nucleotide transhydrogenase, mitoch
35	PDCL	interactor	3	0.667	1.000	Phosducin (PF02114, IPR024253): Phosducin
36	PGRMC1	interactor	5	0.400	3.800	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain SlyX (PF04102, IPR007236): SlyX SCNM1_acidic (PF15805, IPR031625): Acidic C-terminal region of sodium channel modifier 1 SCNM1
37	PSMA1	interactor	33	0.877	28.872	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
38	PSMA2	interactor	32	0.929	13.772	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
39	PSMA3	interactor	32	0.929	11.271	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
40	PSMA4	interactor	29	1.000	0	Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
41	PSMA5	oncoprotein	31	0.942	4.729	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
42	PSMA6	interactor	30	0.986	0.472	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
43	PSMA7	protein found in more fusions	34	0.847	26.362	Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
44	PSMB1	interactor	32	0.881	22.596	Proteasome (PF00227, IPR001353): Proteasome subunit
45	PSMB2	interactor	31	0.931	10.872	Proteasome (PF00227, IPR001353): Proteasome subunit
46	PSMB3	protein found in more fusions	31	0.943	8.390	Proteasome (PF00227, IPR001353): Proteasome subunit
47	PSMB5	interactor	33	0.833	36.637	Proteasome (PF00227, IPR001353): Proteasome subunit
48	PSMB7	protein found in more fusions	31	0.986	0.472	Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
49	PSMC1	interactor	34	0.802	42.367	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
50	PSMC2	protein found in more fusions	33	0.891	15.296	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
51	PSMC3	interactor	33	0.883	19.696	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
52	PSMC4	interactor	31	0.942	4.729	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain
53	PSMC5	protein found in more fusions	36	0.746	105.748	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain
54	PSMC6	interactor	32	0.931	10.872	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
55	PSMD1	interactor	35	0.770	46.713	PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats
56	PSMD11	interactor	31	0.925	27.472	DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat
57	PSMD12	interactor	32	0.929	13.525	Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain
58	PSMD13	interactor	30	0.943	8.390	Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain
59	PSMD14	interactor	30	0.986	0.472	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
60	PSMD2	oncoprotein	35	0.724	76.728	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
61	PSMD3	interactor	32	0.843	32.286	Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
62	PSMD4	interactor	31	0.935	7.353	UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
63	PSMD6	interactor	30	0.938	14.333	RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain
64	PSMD7	interactor	30	0.986	0.472	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus
65	PTGES3	interactor	7	0.533	6.333	CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
66	PTPRK	suppressor	4	0.500	1.917	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Protocadherin (PF08374, IPR013585): Protocadherin Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
67	RHEB	oncoprotein	3	1.000	0	Ras (PF00071, IPR001806, SM00173): Ras family
68	RICTOR	interactor	4	1.000	0	RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5
69	RPS6KB2	interactor	9	0.472	12.819	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
70	RPTOR	protein found in more fusions	6	0.800	1.333	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
71	SSR1	interactor	6	0.333	7.300	TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
72	SUGT1	interactor	8	0.464	11.400	CheC (PF04509, IPR007597): CheC-like family CS (PF04969, IPR007052): CS domain SGS (PF05002, IPR007699): SGS domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
73	SURF1	interactor	4	0.667	2.000	SURF1 (PF02104, IPR002994): SURF1 family
74	TCTN2	interactor	4	0.500	2.333	DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
75	TCTN3	interactor	4	0.500	2.333	DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
76	TERF1	interactor	7	0.600	4.019	TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
77	TMEM216	interactor	5	0.400	5.000	Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
78	TOMM22	interactor	5	0.600	3.667	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
79	UBC	protein found in more fusions	35	0.547	157.707	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
80	UQCRC1	interactor	6	0.400	7.452	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
81	UQCRC2	oncoprotein	13	0.256	44.990	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
82	UQCRFS1	interactor	2	1.000	0	Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region
83	USP19	interactor	4	0.667	1.222	CS (PF04969, IPR007052): CS domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP19_linker (PF16602): Linker region of USP19 deubiquitinase
84	VAPA	interactor	8	0.357	15.333	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
85	VHL	suppressor	10	0.472	11.682	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
86	XRCC3	oncoprotein	2	1.000	0	Rad51 (PF08423, IPR013632): Rad51 RNA_pol_A_CTD (PF03118, IPR011260): Bacterial RNA polymerase, alpha chain C terminal domain
87	YME1L1	interactor	1	0	0	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Peptidase_M41 (PF01434, IPR000642): Peptidase family M41

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List of missing interactors (in fusions)

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	FKBP8	parental protein	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat	L37033

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