Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins FILIP1 (from a repository: Sat Nov 12 09:46:09 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins3 (60.00 %)
The number (and %) of the tumor suppressors1 (20.00 %)
Total number of binary PPIs (saturation %)8 (80.00 %)
The number (and %) of affected PPIs5 (62.50 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI1.600
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: FILIP1 All fusions
: AA092810;
Proteins found in more fusions HSF1 (see 3 fusions); APP (see 4 fusions); FILIP1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 FILIP1parental protein5012.000BAAT_C (PF08840, IPR014940): BAAT / Acyl-CoA thioester hydrolase C terminal
DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
Laminin_II (PF06009, IPR010307): Laminin Domain II
PspB (PF06667, IPR009554): Phage shock protein B
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
2 APPprotein found in more fusions200APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
3 FLNAsuppressor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
4 HSF1protein found in more fusions200DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
5 RAD23Aoncoprotein200UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family

B a c k    t o    T o p ⇑