1 |
TSC22D1 | parental protein | 87 | 0.027 | 10471.677 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TSC22 (PF01166, IPR000580): TSC-22/dip/bun family ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
2 |
FAF1 | parental protein | 124 | 0.075 | 15103.514 | UBX (PF00789, IPR001012, SM00166): UBX domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family AAA_11 (PF13086): AAA domain UBA_4 (PF14555): UBA-like domain |
3 |
A2M | protein found in more fusions | 9 | 0.036 | 66.298 | A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor MP (PF01107, IPR028919): Viral movement protein (MP) SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA) Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region |
4 |
ACVR1 | interactor | 9 | 0.607 | 10.989 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
5 |
ACVR1B | oncoprotein | 8 | 0.536 | 61.035 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
6 |
ACVRL1 | interactor | 5 | 0.200 | 23.817 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
7 |
ALB | interactor | 4 | 0.167 | 27.867 | Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family |
8 |
ALPP | interactor | 7 | 0.619 | 8.792 | Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase |
9 |
AMFR | oncoprotein | 17 | 0.475 | 52.456 | CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
10 |
ANXA1 | suppressor | 10 | 0.083 | 103.741 | Annexin (PF00191, IPR018502, SM00335): Annexin |
11 |
ANXA7 | suppressor | 26 | 0.065 | 655.404 | Annexin (PF00191, IPR018502, SM00335): Annexin |
12 |
APLP1 | interactor | 10 | 0.400 | 32.906 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Ints3 (PF10189, IPR019333): Integrator complex subunit 3 APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
13 |
ASAH1 | interactor | 2 | 1.000 | 0 | CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase |
14 |
ASCC2 | interactor | 3 | 1.000 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3 |
15 |
ASNA1 | interactor | 11 | 0.545 | 63.484 | ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase |
16 |
ASPSCR1 | oncoprotein | 13 | 0.615 | 36.776 | DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192) Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) UBX (PF00789, IPR001012, SM00166): UBX domain TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain |
17 |
BAG6 | interactor | 28 | 0.217 | 617.189 | DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
18 |
BMPR1A | suppressor | 8 | 0.667 | 6.129 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
19 |
BMPR1B | interactor | 5 | 0.833 | 0.909 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
20 |
BTBD9 | interactor | 4 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain |
21 |
BTRC | oncoprotein | 21 | 0.337 | 167.909 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
22 |
C14orf1 | interactor | 6 | 0 | 41.490 | Erg28 (PF03694, IPR005352): Erg28 like protein |
23 |
CA10 | interactor | 2 | 1.000 | 0 | Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase |
24 |
CACNA1A | interactor | 6 | 0.133 | 23.427 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
25 |
CARHSP1 | interactor | 2 | 0 | 2.508 | DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339) |
26 |
CARM1 | oncoprotein | 13 | 0.462 | 24.914 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
27 |
CARS | oncoprotein | 10 | 0.800 | 4.798 | tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain |
28 |
CASP8 | suppressor | 11 | 0.378 | 99.943 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
29 |
CBX3 | interactor | 8 | 0.333 | 31.513 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
30 |
CCDC90B | interactor | 3 | 0 | 4.925 | DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640) |
31 |
CD2AP | protein found in more fusions | 9 | 0.214 | 74.048 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil |
32 |
CD40 | protein found in more fusions | 4 | 0.667 | 0.637 | Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
33 |
CDC5L | interactor | 29 | 0.230 | 374.578 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
34 |
CDC73 | suppressor | 10 | 0.200 | 235.783 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
35 |
CDK2 | suppressor | 28 | 0.236 | 406.447 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
CDKN1A | suppressor | 43 | 0.114 | 1471.353 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
37 |
CDT1 | oncoprotein | 4 | 0.833 | 1.466 | CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain |
38 |
CHD3 | oncoprotein | 17 | 0.133 | 248.354 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
39 |
COPB2 | interactor | 8 | 0.333 | 25.449 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
40 |
CORO2B | oncoprotein | 1 | 0 | 0 | DivIC (PF04977, IPR007060): Septum formation initiator DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
41 |
CRMP1 | interactor | 14 | 0.244 | 149.293 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family |
42 |
CSNK2B | interactor | 21 | 0.147 | 472.528 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
43 |
CTNNB1 | oncoprotein | 24 | 0.210 | 428.040 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
44 |
CUL1 | suppressor | 43 | 0.214 | 792.312 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
45 |
CUL2 | suppressor | 26 | 0.286 | 287.523 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
46 |
CUL3 | protein found in more fusions | 64 | 0.138 | 1926.207 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
47 |
DDAH2 | interactor | 9 | 0.028 | 78.817 | Amidinotransf (PF02274, IPR003198): Amidinotransferase |
48 |
DDOST | interactor | 7 | 0.429 | 45.196 | DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta |
49 |
DHDH | interactor | 1 | 0 | 0 | GFO_IDH_MocA (PF01408, IPR000683): Oxidoreductase family, NAD-binding Rossmann fold |
50 |
DNAAF5 | interactor | 5 | 0.200 | 35.539 | HEAT (PF02985, IPR000357): HEAT repeat Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain |
51 |
DNAJA1 | interactor | 14 | 0.549 | 28.035 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
52 |
DNAJB11 | interactor | 14 | 0.308 | 166.740 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
53 |
DNMT3B | suppressor | 9 | 0.222 | 74.217 | DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain |
54 |
DYNC1H1 | interactor | 11 | 0.309 | 106.006 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
55 |
EED | suppressor | 19 | 0.144 | 224.612 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
56 |
EMC1 | interactor | 3 | 0.333 | 2.995 | DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620) PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat PQQ_2 (PF13360, IPR002372): PQQ-like domain |
57 |
EPPK1 | interactor | 8 | 0.286 | 68.811 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal |
58 |
FADD | suppressor | 5 | 0.700 | 3.670 | Death (PF00531, IPR000488, SM00005): Death domain DED (PF01335, IPR001875, SM00031): Death effector domain Hpt (PF01627, IPR008207, SM00073): Hpt domain |
59 |
FAM114A1 | interactor | 3 | 0.667 | 0.711 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
60 |
FAM20C | interactor | 3 | 0 | 14.373 | Fam20C (PF06702, IPR009581): Golgi casein kinase, C-terminal, Fam20 FAM198 (PF15051, IPR029207): FAM198 protein |
61 |
FARSB | interactor | 13 | 0.577 | 44.922 | B3_4 (PF03483, IPR005146, SM00873): B3/4 domain B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain |
62 |
FAS | suppressor | 10 | 0.194 | 72.200 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH |
63 |
FBN3 | interactor | 6 | 0.067 | 35.643 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain TB (PF00683, IPR017878): TB domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
64 |
FBXW11 | interactor | 16 | 0.286 | 143.080 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
65 |
G3BP1 | protein found in more fusions | 10 | 0.500 | 13.442 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
66 |
GART | interactor | 17 | 0.574 | 32.959 | AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain Formyl_trans_N (PF00551, IPR002376): Formyl transferase GARS_A (PF01071, IPR020561): Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C (PF02843, IPR020560): Phosphoribosylglycinamide synthetase, C domain GARS_N (PF02844, IPR020562): Phosphoribosylglycinamide synthetase, N domain |
67 |
GCN1 | interactor | 6 | 0.333 | 33.823 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
68 |
GET4 | interactor | 11 | 0.727 | 12.063 | DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410) Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 |
69 |
GNB2 | interactor | 9 | 0.361 | 33.800 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain |
70 |
GNB5 | interactor | 4 | 0.167 | 6.206 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
71 |
GSTK1 | interactor | 8 | 0.238 | 35.422 | DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain |
72 |
HIF1A | suppressor | 13 | 0.487 | 25.094 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
73 |
HIRIP3 | interactor | 17 | 0.507 | 40.518 | CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ |
74 |
HIST1H4A | interactor | 17 | 0.434 | 62.404 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
75 |
HMGXB4 | oncoprotein | 4 | 0 | 43.339 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4171 (PF13775, IPR025228): Domain of unknown function (DUF4171) RMP (PF14996, IPR029239): Retinal Maintenance |
76 |
HNRNPM | interactor | 19 | 0.298 | 179.677 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
77 |
HSD17B10 | interactor | 8 | 0.393 | 25.301 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
78 |
HSPA2 | interactor | 7 | 0.524 | 8.960 | HSP70 (PF00012, IPR013126): Hsp70 protein |
79 |
HSPA4 | interactor | 29 | 0.232 | 456.657 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
80 |
HSPA8 | oncoprotein | 27 | 0.333 | 235.777 | HSP70 (PF00012, IPR013126): Hsp70 protein |
81 |
HSPH1 | oncoprotein | 24 | 0.377 | 128.862 | HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain |
82 |
IARS | interactor | 10 | 0.333 | 79.062 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
83 |
IGF2 | oncoprotein | 2 | 1.000 | 0 | IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family |
84 |
IKBKAP | interactor | 12 | 0.364 | 62.414 | IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis |
85 |
IKBKB | protein found in more fusions | 15 | 0.264 | 171.802 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
86 |
ILK | suppressor | 16 | 0.305 | 102.838 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
87 |
IPO5 | interactor | 6 | 0.667 | 10.004 | HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat AAA_30 (PF13604): AAA domain HEAT_2 (PF13646): HEAT repeats PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
88 |
ITGB1BP1 | interactor | 1 | 0 | 0 | ICAP-1_inte_bdg (PF10480, IPR019517): Beta-1 integrin binding protein |
89 |
KBTBD7 | interactor | 5 | 0.600 | 17.856 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_2 (PF07646, IPR011498): Kelch motif Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif |
90 |
KCTD10 | interactor | 7 | 0.857 | 2.807 | BTB_2 (PF02214, IPR003131): BTB/POZ domain |
91 |
KCTD13 | interactor | 6 | 1.000 | 0 | BTB_2 (PF02214, IPR003131): BTB/POZ domain |
92 |
KLHL22 | interactor | 5 | 0.900 | 0.467 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif |
93 |
KMT2B | oncoprotein | 7 | 0.048 | 34.131 | FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus GRP (PF07172, IPR010800): Glycine rich protein family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
94 |
KMT2C | suppressor | 2 | 0 | 9.008 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus SLC12 (PF03522, IPR018491): Solute carrier family 12 MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box zf-HC5HC2H (PF13771): PHD-like zinc-binding domain zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain |
95 |
LARP7 | interactor | 5 | 0.200 | 38.834 | Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
96 |
LRIF1 | interactor | 17 | 0.183 | 227.328 | LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1 |
97 |
MAGIX | interactor | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
98 |
MAP3K12 | interactor | 2 | 1.000 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
99 |
MCM3AP | interactor | 3 | 0 | 20.238 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP |
100 |
MIOS | interactor | 4 | 0.667 | 7.775 | zinc_ribbon_16 (PF17034, IPR031488): Zinc-ribbon like family |
101 |
MMAB | interactor | 1 | 0 | 0 | Cob_adeno_trans (PF01923, IPR016030): Cobalamin adenosyltransferase |
102 |
MTR | interactor | 4 | 0.333 | 12.638 | B12-binding (PF02310, IPR006158): B12 binding domain B12-binding_2 (PF02607, IPR003759, SM01018): B12 binding domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase Met_synt_B12 (PF02965, IPR004223): Vitamin B12 dependent methionine synthase, activation domain Pterin_bind (PF00809, IPR000489): Pterin binding enzyme S-methyl_trans (PF02574, IPR003726): Homocysteine S-methyltransferase DUF2760 (PF10816, IPR021212): Domain of unknown function (DUF2760) |
103 |
MYCBP2 | interactor | 4 | 1.000 | 0 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Filamin (PF00630, IPR017868): Filamin/ABP280 repeat Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHR (PF08005, IPR012983): PHR domain RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat SH3_3 (PF08239, IPR003646): Bacterial SH3 domain XPA_N (PF01286, IPR022652): XPA protein N-terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
104 |
NCOA5 | suppressor | 4 | 0.667 | 1.077 | Macoilin (PF09726, IPR019130): Transmembrane protein |
105 |
NDUFA9 | interactor | 3 | 0.333 | 15.599 | Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family |
106 |
NGLY1 | interactor | 5 | 0.700 | 1.700 | PUB (PF09409, IPR018997): PUB domain Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
107 |
NLRP12 | interactor | 3 | 1.000 | 0 | NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain |
108 |
NLRP2 | oncoprotein | 2 | 1.000 | 0 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) AAA_16 (PF13191): AAA ATPase domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
109 |
NLRP3 | oncoprotein | 2 | 1.000 | 0 | NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain |
110 |
NLRP7 | interactor | 1 | 0 | 0 | NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
111 |
NPLOC4 | interactor | 16 | 0.575 | 90.033 | NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4 |
112 |
NR1H2 | oncoprotein | 9 | 0.167 | 152.006 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
113 |
NR4A1 | suppressor | 7 | 0.333 | 50.774 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
114 |
NRBP1 | suppressor | 8 | 0.286 | 47.149 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
115 |
NSFL1C | interactor | 18 | 0.536 | 55.669 | SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain |
116 |
NTRK1 | oncoprotein | 85 | 0.103 | 4313.195 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
117 |
NUDT21 | protein found in more fusions | 15 | 0.209 | 176.764 | NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase |
118 |
NUP50 | interactor | 6 | 0.400 | 18.813 | NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain |
119 |
NUP93 | oncoprotein | 7 | 0.381 | 26.822 | Nic96 (PF04097, IPR007231): Nup93/Nic96 |
120 |
NUP98 | suppressor | 7 | 0.333 | 20.773 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
121 |
OTUB1 | interactor | 24 | 0.207 | 528.239 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
122 |
PDHB | interactor | 9 | 0.194 | 60.762 | Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain |
123 |
PJA2 | protein found in more fusions | 7 | 0.667 | 6.656 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
124 |
PLOD2 | protein found in more fusions | 16 | 0.552 | 20.761 | 2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1 Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 |
125 |
PPM1G | interactor | 13 | 0.513 | 52.061 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PP2C (PF00481, IPR001932): Protein phosphatase 2C DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
126 |
PPP2R5C | suppressor | 4 | 0.333 | 3.440 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) DUF1616 (PF07760, IPR011674): Protein of unknown function (DUF1616) |
127 |
PRKCI | interactor | 3 | 0.333 | 18.834 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
128 |
PRMT3 | interactor | 13 | 0.564 | 27.344 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) |
129 |
PTN | oncoprotein | 8 | 0.143 | 40.208 | PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain |
130 |
PUF60 | protein found in more fusions | 17 | 0.308 | 140.352 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
131 |
QARS | interactor | 10 | 0.356 | 42.778 | tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 |
132 |
RAD23A | oncoprotein | 10 | 0.500 | 32.500 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
133 |
RAE1 | interactor | 15 | 0.276 | 112.236 | Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
134 |
RANBP3 | oncoprotein | 17 | 0.537 | 123.779 | Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor |
135 |
RAP1A | suppressor | 7 | 0.381 | 22.419 | Ras (PF00071, IPR001806, SM00173): Ras family |
136 |
RAP1B | oncoprotein | 11 | 0.055 | 126.653 | Ras (PF00071, IPR001806, SM00173): Ras family |
137 |
RCC1 | interactor | 18 | 0.072 | 313.018 | RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
138 |
RELA | oncoprotein | 18 | 0.324 | 109.676 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
139 |
RGS1 | oncoprotein | 2 | 1.000 | 0 | RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
140 |
RPA3 | interactor | 15 | 0.286 | 145.780 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
141 |
RPL24 | interactor | 19 | 0.368 | 96.643 | MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e |
142 |
RPL5 | suppressor | 14 | 0.333 | 83.245 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
143 |
RPN2 | interactor | 12 | 0.364 | 115.301 | Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II |
144 |
SAMHD1 | interactor | 15 | 0.615 | 18.938 | HD (PF01966, IPR006674): HD domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
145 |
SEC23A | interactor | 19 | 0.491 | 54.741 | Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
146 |
SET | oncoprotein | 14 | 0.538 | 53.069 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
147 |
SETDB1 | interactor | 12 | 0.333 | 110.438 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator |
148 |
SF1 | protein found in more fusions | 17 | 0.567 | 50.906 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
149 |
SFXN1 | interactor | 2 | 0 | 1.050 | Mtc (PF03820, IPR004686): Tricarboxylate carrier |
150 |
SIRT6 | suppressor | 11 | 0.164 | 58.310 | SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
151 |
SKIL | suppressor | 5 | 0 | 34.729 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
152 |
SKP1 | oncoprotein | 15 | 0.467 | 80.971 | Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
153 |
SLC25A22 | interactor | 5 | 0.300 | 22.677 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257) |
154 |
SMAD6 | interactor | 9 | 0.417 | 54.847 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
155 |
SMAD7 | interactor | 11 | 0.418 | 87.789 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
156 |
SNRNP200 | protein found in more fusions | 11 | 0.267 | 55.569 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
157 |
SP110 | oncoprotein | 4 | 0.167 | 6.132 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
158 |
SPACA9 | interactor | 1 | 0 | 0 | DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561) |
159 |
SPRED1 | interactor | 4 | 0 | 13.713 | SMC_ScpA (PF02616, IPR003768): Segregation and condensation protein ScpA Sprouty (PF05210, IPR007875): Sprouty protein (Spry) WH1 (PF00568, IPR000697, SM00461): WH1 domain |
160 |
SRPRB | interactor | 7 | 0.381 | 37.065 | MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit |
161 |
SWAP70 | oncoprotein | 9 | 0.500 | 21.493 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) GrpE (PF01025, IPR000740): GrpE PH (PF00169, IPR001849, SM00233): PH domain CotJB (PF12652, IPR024207): CotJB protein EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
162 |
TAF1D | interactor | 9 | 0.056 | 173.067 | TAF1D (PF15333, IPR027976): TATA box-binding protein-associated factor 1D |
163 |
TAF5L | interactor | 4 | 0.500 | 3.354 | TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
164 |
TCEAL1 | interactor | 4 | 0.500 | 1.338 | BEX (PF04538, IPR021156): Brain expressed X-linked like family |
165 |
TGFBR1 | oncoprotein | 9 | 0.278 | 79.792 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
166 |
TGFBR2 | suppressor | 7 | 0.571 | 16.370 | ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
167 |
TK1 | oncoprotein | 26 | 0.083 | 785.315 | TK (PF00265, IPR001267, SM00203): Thymidine kinase |
168 |
TLE1 | interactor | 11 | 0.067 | 66.658 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
169 |
TLN1 | interactor | 7 | 0.476 | 23.846 | DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
170 |
TNFAIP1 | oncoprotein | 8 | 0.714 | 9.161 | BTB_2 (PF02214, IPR003131): BTB/POZ domain |
171 |
TNNT1 | protein found in more fusions | 7 | 0.133 | 61.139 | Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050) |
172 |
TP53 | suppressor | 44 | 0.128 | 1266.282 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
173 |
TROVE2 | interactor | 18 | 0.536 | 44.359 | TROVE (PF05731, IPR008858): TROVE domain DUF2201 (PF09967, IPR018698): VWA-like domain (DUF2201) |
174 |
TSC22D4 | interactor | 6 | 0.333 | 34.212 | AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
175 |
TTI1 | interactor | 5 | 0.500 | 8.328 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal |
176 |
UBC | protein found in more fusions | 45 | 0.224 | 829.618 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
177 |
UBE2D1 | interactor | 25 | 0.159 | 431.412 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
178 |
UBL4A | interactor | 22 | 0.312 | 137.257 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
179 |
UBR1 | interactor | 9 | 0.694 | 7.721 | ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
180 |
UBR2 | interactor | 6 | 0.467 | 14.735 | ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
181 |
UBR4 | interactor | 11 | 0.473 | 32.039 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family |
182 |
UBXN1 | interactor | 30 | 0.293 | 239.655 | Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain |
183 |
UBXN2B | interactor | 6 | 0.600 | 4.323 | SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain |
184 |
UBXN6 | interactor | 8 | 0.857 | 2.846 | PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain |
185 |
UBXN7 | interactor | 30 | 0.313 | 245.661 | UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
186 |
UFD1L | interactor | 17 | 0.493 | 101.360 | UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1 |
187 |
UGP2 | protein found in more fusions | 19 | 0.412 | 78.922 | UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase |
188 |
UNC119 | interactor | 7 | 0.048 | 34.131 | GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit |
189 |
UNK | interactor | 16 | 0.125 | 227.938 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
190 |
UROD | protein found in more fusions | 5 | 0.167 | 46.699 | URO-D (PF01208, IPR000257): Uroporphyrinogen decarboxylase (URO-D) |
191 |
USP11 | protein found in more fusions | 18 | 0.294 | 290.406 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
192 |
VAPA | interactor | 9 | 0.472 | 38.810 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
193 |
VAPB | interactor | 11 | 0.655 | 12.768 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
194 |
VCP | protein found in more fusions | 45 | 0.241 | 1041.315 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
195 |
VCPIP1 | interactor | 14 | 0.626 | 57.068 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SDP_N (PF12278, IPR022063): Sex determination protein N terminal |
196 |
VIM | suppressor | 26 | 0.223 | 433.934 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
197 |
WDR24 | interactor | 4 | 0.833 | 0.500 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type |
198 |
WDR26 | interactor | 5 | 0.800 | 1.393 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
199 |
WDR59 | interactor | 4 | 0.667 | 7.775 | RWD (PF05773, IPR006575, SM00591): RWD domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DZR (PF12773, IPR025874): Double zinc ribbon ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type |
200 |
WDR73 | interactor | 4 | 0.167 | 6.132 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
201 |
WDYHV1 | interactor | 3 | 0.333 | 16.998 | Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase |
202 |
WIZ | interactor | 6 | 0.133 | 24.383 | AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog) C1_2 (PF03107, IPR004146): C1 domain Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST zf-C2H2_4 (PF13894): C2H2-type zinc finger |
203 |
WNK1 | interactor | 4 | 0.333 | 5.364 | SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pkinase (PF00069, IPR000719): Protein kinase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal |
204 |
XPO7 | interactor | 17 | 0.596 | 29.030 | IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain |
205 |
YTHDF1 | interactor | 7 | 0.381 | 15.832 | YTH (PF04146, IPR007275): YT521-B-like domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) |
206 |
YTHDF3 | interactor | 4 | 0.333 | 6.688 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit YTH (PF04146, IPR007275): YT521-B-like domain |
207 |
ZC3H15 | interactor | 3 | 0.667 | 3.895 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus (PF16131, IPR032297): Torus domain DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46 |
208 |
ZC3HC1 | interactor | 4 | 0.333 | 11.171 | Rsm1 (PF08600, IPR013909): Rsm1-like zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like |