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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)208
The number (and %) of the onco-proteins51 (24.52 %)
The number (and %) of the tumor suppressors28 (13.46 %)
Total number of binary PPIs (saturation %)1330 (6.18 %)
The number (and %) of affected PPIs210 (15.79 %)
The number of possible different fusions29
PPI diameter3
PPI radius2
The average degree of PPI12.192
Assortativity coefficient-0.1481
The network average Clustering coefficient0.381
The number (and %) of a zero Clustering coefficients17 (8.17 %)
The number (and %) of a zero Betweenness Centrality19 (9.13 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TSC22D1,FAF1 All fusions
Proteins found in more fusions CUL1 (see 3 fusions); CUL3 (see 1 fusions); TNFAIP1 (see 1 fusions); PJA2 (see 1 fusions); TSC22D1 (see 5 fusions); IKBKB (see 2 fusions); NUDT21 (see 2 fusions); UBC (see 1 fusions); TP53 (see 3 fusions); UGP2 (see 1 fusions); ILK (see 1 fusions); G3BP1 (see 1 fusions); VCP (see 4 fusions); PUF60 (see 2 fusions); BMPR1A (see 1 fusions); NCOA5 (see 1 fusions); PLOD2 (see 1 fusions); A2M (see 2 fusions); FAF1 (see 2 fusions); CD2AP (see 1 fusions); SNRNP200 (see 3 fusions); CD40 (see 2 fusions); SF1 (see 1 fusions); CHD3 (see 1 fusions); USP11 (see 4 fusions); UROD (see 1 fusions); TNNT1 (see 1 fusions); TSC22D1/FAF1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TSC22D1parental protein870.02710471.677SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
2 FAF1parental protein1240.07515103.514UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
3 A2Mprotein found in more fusions90.03666.298A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
4 ACVR1interactor90.60710.989Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
5 ACVR1Boncoprotein80.53661.035Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
6 ACVRL1interactor50.20023.817Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
7 ALBinteractor40.16727.867Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
8 ALPPinteractor70.6198.792Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase
9 AMFRoncoprotein170.47552.456CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
10 ANXA1suppressor100.083103.741Annexin (PF00191, IPR018502, SM00335): Annexin
11 ANXA7suppressor260.065655.404Annexin (PF00191, IPR018502, SM00335): Annexin
12 APLP1interactor100.40032.906APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
Ints3 (PF10189, IPR019333): Integrator complex subunit 3
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
13 ASAH1interactor21.0000CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family
NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
14 ASCC2interactor31.0000CUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
15 ASNA1interactor110.54563.484ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase
16 ASPSCR1oncoprotein130.61536.776DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
17 BAG6interactor280.217617.189DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
18 BMPR1Asuppressor80.6676.129Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
19 BMPR1Binteractor50.8330.909Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
20 BTBD9interactor41.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
21 BTRConcoprotein210.337167.909WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
22 C14orf1interactor6041.490Erg28 (PF03694, IPR005352): Erg28 like protein
23 CA10interactor21.0000Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
24 CACNA1Ainteractor60.13323.427Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
25 CARHSP1interactor202.508DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
26 CARM1oncoprotein130.46224.914K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
27 CARSoncoprotein100.8004.798tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain
28 CASP8suppressor110.37899.943DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
29 CBX3interactor80.33331.513Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
30 CCDC90Binteractor304.925DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
31 CD2APprotein found in more fusions90.21474.048SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
32 CD40protein found in more fusions40.6670.637Glycophorin_A (PF01102, IPR001195): Glycophorin A
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
33 CDC5Linteractor290.230374.578OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
34 CDC73suppressor100.200235.783CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
35 CDK2suppressor280.236406.447Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
36 CDKN1Asuppressor430.1141471.353CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
37 CDT1oncoprotein40.8331.466CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like
CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
38 CHD3oncoprotein170.133248.354CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
39 COPB2interactor80.33325.449Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
40 CORO2Boncoprotein100DivIC (PF04977, IPR007060): Septum formation initiator
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
41 CRMP1interactor140.244149.293Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
42 CSNK2Binteractor210.147472.528CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
43 CTNNB1oncoprotein240.210428.040Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
44 CUL1suppressor430.214792.312Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
45 CUL2suppressor260.286287.523Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
46 CUL3protein found in more fusions640.1381926.207Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
47 DDAH2interactor90.02878.817Amidinotransf (PF02274, IPR003198): Amidinotransferase
48 DDOSTinteractor70.42945.196DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
49 DHDHinteractor100GFO_IDH_MocA (PF01408, IPR000683): Oxidoreductase family, NAD-binding Rossmann fold
50 DNAAF5interactor50.20035.539HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
51 DNAJA1interactor140.54928.035DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
52 DNAJB11interactor140.308166.740DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
53 DNMT3Bsuppressor90.22274.217DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
54 DYNC1H1interactor110.309106.006AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1
DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1
AAA_7 (PF12775): P-loop containing dynein motor region D3
MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor
AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4
AAA_9 (PF12781): ATP-binding dynein motor region D5
55 EEDsuppressor190.144224.612WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
56 EMC1interactor30.3332.995DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620)
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
PQQ_2 (PF13360, IPR002372): PQQ-like domain
57 EPPK1interactor80.28668.811DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HupF_HypC (PF01455, IPR001109): HupF/HypC family
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
58 FADDsuppressor50.7003.670Death (PF00531, IPR000488, SM00005): Death domain
DED (PF01335, IPR001875, SM00031): Death effector domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
59 FAM114A1interactor30.6670.711DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
60 FAM20Cinteractor3014.373Fam20C (PF06702, IPR009581): Golgi casein kinase, C-terminal, Fam20
FAM198 (PF15051, IPR029207): FAM198 protein
61 FARSBinteractor130.57744.922B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
62 FASsuppressor100.19472.200Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
63 FBN3interactor60.06735.643EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
64 FBXW11interactor160.286143.080WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
65 G3BP1protein found in more fusions100.50013.442NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
66 GARTinteractor170.57432.959AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
Formyl_trans_N (PF00551, IPR002376): Formyl transferase
GARS_A (PF01071, IPR020561): Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
GARS_C (PF02843, IPR020560): Phosphoribosylglycinamide synthetase, C domain
GARS_N (PF02844, IPR020562): Phosphoribosylglycinamide synthetase, N domain
67 GCN1interactor60.33333.823Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
68 GET4interactor110.72712.063DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410)
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
69 GNB2interactor90.36133.800WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CALM_bind (PF16025): Calcium-dependent calmodulin binding
WD40_like (PF17005, IPR031544): WD40-like domain
70 GNB5interactor40.1676.206WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
71 GSTK1interactor80.23835.422DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain
72 HIF1Asuppressor130.48725.094Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
73 HIRIP3interactor170.50740.518CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ
74 HIST1H4Ainteractor170.43462.404CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
75 HMGXB4oncoprotein4043.339DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF4171 (PF13775, IPR025228): Domain of unknown function (DUF4171)
RMP (PF14996, IPR029239): Retinal Maintenance
76 HNRNPMinteractor190.298179.677RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
77 HSD17B10interactor80.39325.301adh_short (PF00106, IPR002198): short chain dehydrogenase
78 HSPA2interactor70.5248.960HSP70 (PF00012, IPR013126): Hsp70 protein
79 HSPA4interactor290.232456.657Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
80 HSPA8oncoprotein270.333235.777HSP70 (PF00012, IPR013126): Hsp70 protein
81 HSPH1oncoprotein240.377128.862HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
82 IARSinteractor100.33379.062Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
83 IGF2oncoprotein21.0000IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide
Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family
84 IKBKAPinteractor120.36462.414IKI3 (PF04762, IPR006849): IKI3 family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
85 IKBKBprotein found in more fusions150.264171.802FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
86 ILKsuppressor160.305102.838Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
87 IPO5interactor60.66710.004HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
AAA_30 (PF13604): AAA domain
HEAT_2 (PF13646): HEAT repeats
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
88 ITGB1BP1interactor100ICAP-1_inte_bdg (PF10480, IPR019517): Beta-1 integrin binding protein
89 KBTBD7interactor50.60017.856BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
90 KCTD10interactor70.8572.807BTB_2 (PF02214, IPR003131): BTB/POZ domain
91 KCTD13interactor61.0000BTB_2 (PF02214, IPR003131): BTB/POZ domain
92 KLHL22interactor50.9000.467BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
93 KMT2Boncoprotein70.04834.131FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
GRP (PF07172, IPR010800): Glycine rich protein family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
94 KMT2Csuppressor209.008AT_hook (PF02178, IPR017956, SM00384): AT hook motif
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
SLC12 (PF03522, IPR018491): Solute carrier family 12
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
95 LARP7interactor50.20038.834Agouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
96 LRIF1interactor170.183227.328LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
97 MAGIXinteractor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
98 MAP3K12interactor21.0000APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
99 MCM3APinteractor3020.238RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAC3_GANP (PF03399, IPR005062): SAC3/GANP family
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2
NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein
MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
100 MIOSinteractor40.6677.775zinc_ribbon_16 (PF17034, IPR031488): Zinc-ribbon like family
101 MMABinteractor100Cob_adeno_trans (PF01923, IPR016030): Cobalamin adenosyltransferase
102 MTRinteractor40.33312.638B12-binding (PF02310, IPR006158): B12 binding domain
B12-binding_2 (PF02607, IPR003759, SM01018): B12 binding domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
Met_synt_B12 (PF02965, IPR004223): Vitamin B12 dependent methionine synthase, activation domain
Pterin_bind (PF00809, IPR000489): Pterin binding enzyme
S-methyl_trans (PF02574, IPR003726): Homocysteine S-methyltransferase
DUF2760 (PF10816, IPR021212): Domain of unknown function (DUF2760)
103 MYCBP2interactor41.0000ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHR (PF08005, IPR012983): PHR domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SH3_3 (PF08239, IPR003646): Bacterial SH3 domain
XPA_N (PF01286, IPR022652): XPA protein N-terminal
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
104 NCOA5suppressor40.6671.077Macoilin (PF09726, IPR019130): Transmembrane protein
105 NDUFA9interactor30.33315.599Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
106 NGLY1interactor50.7001.700PUB (PF09409, IPR018997): PUB domain
Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain
PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
107 NLRP12interactor31.0000NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
108 NLRP2oncoprotein21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
AAA_16 (PF13191): AAA ATPase domain
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
109 NLRP3oncoprotein21.0000NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
110 NLRP7interactor100NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
111 NPLOC4interactor160.57590.033NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
112 NR1H2oncoprotein90.167152.006zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
113 NR4A1suppressor70.33350.774zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
114 NRBP1suppressor80.28647.149Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
115 NSFL1Cinteractor180.53655.669SEP (PF08059, IPR012989, SM00553): SEP domain
UBX (PF00789, IPR001012, SM00166): UBX domain
UBA_4 (PF14555): UBA-like domain
116 NTRK1oncoprotein850.1034313.195I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
117 NUDT21protein found in more fusions150.209176.764NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
118 NUP50interactor60.40018.813NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa)
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
119 NUP93oncoprotein70.38126.822Nic96 (PF04097, IPR007231): Nup93/Nic96
120 NUP98suppressor70.33320.773Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase
Nup96 (PF12110, IPR021967): Nuclear protein 96
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
121 OTUB1interactor240.207528.239Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
122 PDHBinteractor90.19460.762Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
123 PJA2protein found in more fusions70.6676.656zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
124 PLOD2protein found in more fusions160.55220.7612OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
125 PPM1Ginteractor130.51352.061Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PP2C (PF00481, IPR001932): Protein phosphatase 2C
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
126 PPP2R5Csuppressor40.3333.440B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
DUF1616 (PF07760, IPR011674): Protein of unknown function (DUF1616)
127 PRKCIinteractor30.33318.834PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
128 PRMT3interactor130.56427.344PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
129 PTNoncoprotein80.14340.208PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
130 PUF60protein found in more fusions170.308140.352RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Titin_Z (PF09042, IPR015129): Titin Z
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
131 QARSinteractor100.35642.778tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
132 RAD23Aoncoprotein100.50032.500UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
133 RAE1interactor150.276112.236Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
134 RANBP3oncoprotein170.537123.779Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
135 RAP1Asuppressor70.38122.419Ras (PF00071, IPR001806, SM00173): Ras family
136 RAP1Boncoprotein110.055126.653Ras (PF00071, IPR001806, SM00173): Ras family
137 RCC1interactor180.072313.018RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
138 RELAoncoprotein180.324109.676DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
139 RGS1oncoprotein21.0000RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
140 RPA3interactor150.286145.780Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
141 RPL24interactor190.36896.643MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
142 RPL5suppressor140.33383.245Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
143 RPN2interactor120.364115.301Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
144 SAMHD1interactor150.61518.938HD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
145 SEC23Ainteractor190.49154.741Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
146 SEToncoprotein140.53853.069NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
147 SETDB1interactor120.333110.438MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
148 SF1protein found in more fusions170.56750.906UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
149 SFXN1interactor201.050Mtc (PF03820, IPR004686): Tricarboxylate carrier
150 SIRT6suppressor110.16458.310SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
151 SKILsuppressor5034.729c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
152 SKP1oncoprotein150.46780.971Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
153 SLC25A22interactor50.30022.677Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
154 SMAD6interactor90.41754.847MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
155 SMAD7interactor110.41887.789MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
156 SNRNP200protein found in more fusions110.26755.569DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
157 SP110oncoprotein40.1676.132Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain; Sp100 domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
158 SPACA9interactor100DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
159 SPRED1interactor4013.713SMC_ScpA (PF02616, IPR003768): Segregation and condensation protein ScpA
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
WH1 (PF00568, IPR000697, SM00461): WH1 domain
160 SRPRBinteractor70.38137.065MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
161 SWAP70oncoprotein90.50021.493DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
GrpE (PF01025, IPR000740): GrpE
PH (PF00169, IPR001849, SM00233): PH domain
CotJB (PF12652, IPR024207): CotJB protein
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
162 TAF1Dinteractor90.056173.067TAF1D (PF15333, IPR027976): TATA box-binding protein-associated factor 1D
163 TAF5Linteractor40.5003.354TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
164 TCEAL1interactor40.5001.338BEX (PF04538, IPR021156): Brain expressed X-linked like family
165 TGFBR1oncoprotein90.27879.792Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
166 TGFBR2suppressor70.57116.370ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
167 TK1oncoprotein260.083785.315TK (PF00265, IPR001267, SM00203): Thymidine kinase
168 TLE1interactor110.06766.658TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
169 TLN1interactor70.47623.846DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Talin_middle (PF09141, IPR015224): Talin, middle domain
VBS (PF08913, IPR015009): Vinculin Binding Site
CoatB (PF10389, IPR008020): Bacteriophage coat protein B
LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
170 TNFAIP1oncoprotein80.7149.161BTB_2 (PF02214, IPR003131): BTB/POZ domain
171 TNNT1protein found in more fusions70.13361.139Troponin (PF00992, IPR001978): Troponin
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
172 TP53suppressor440.1281266.282DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
173 TROVE2interactor180.53644.359TROVE (PF05731, IPR008858): TROVE domain
DUF2201 (PF09967, IPR018698): VWA-like domain (DUF2201)
174 TSC22D4interactor60.33334.212AflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
175 TTI1interactor50.5008.328Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
VHS (PF00790, IPR002014, SM00288): VHS domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
176 UBCprotein found in more fusions450.224829.618ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
177 UBE2D1interactor250.159431.412UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
178 UBL4Ainteractor220.312137.257ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
179 UBR1interactor90.6947.721ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea
ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
180 UBR2interactor60.46714.735ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
181 UBR4interactor110.47332.039CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
RecR (PF02132, IPR023628): RecR protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
DZR (PF12773, IPR025874): Double zinc ribbon
E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4
FAM176 (PF14851): FAM176 family
182 UBXN1interactor300.293239.655Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
183 UBXN2Binteractor60.6004.323SEP (PF08059, IPR012989, SM00553): SEP domain
UBX (PF00789, IPR001012, SM00166): UBX domain
184 UBXN6interactor80.8572.846PUB (PF09409, IPR018997): PUB domain
UBX (PF00789, IPR001012, SM00166): UBX domain
185 UBXN7interactor300.313245.661UBX (PF00789, IPR001012, SM00166): UBX domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
186 UFD1Linteractor170.493101.360UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
187 UGP2protein found in more fusions190.41278.922UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
188 UNC119interactor70.04834.131GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
189 UNKinteractor160.125227.938MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
190 URODprotein found in more fusions50.16746.699URO-D (PF01208, IPR000257): Uroporphyrinogen decarboxylase (URO-D)
191 USP11protein found in more fusions180.294290.406Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
192 VAPAinteractor90.47238.810DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
193 VAPBinteractor110.65512.768ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
194 VCPprotein found in more fusions450.2411041.315AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
195 VCPIP1interactor140.62657.068ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
SDP_N (PF12278, IPR022063): Sex determination protein N terminal
196 VIMsuppressor260.223433.934Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
197 WDR24interactor40.8330.500WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
198 WDR26interactor50.8001.393eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
199 WDR59interactor40.6677.775RWD (PF05773, IPR006575, SM00591): RWD domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DZR (PF12773, IPR025874): Double zinc ribbon
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
200 WDR73interactor40.1676.132WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
201 WDYHV1interactor30.33316.998Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase
202 WIZinteractor60.13324.383AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
C1_2 (PF03107, IPR004146): C1 domain
Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST
zf-C2H2_4 (PF13894): C2H2-type zinc finger
203 WNK1interactor40.3335.364SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Pkinase (PF00069, IPR000719): Protein kinase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
204 XPO7interactor170.59629.030IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
205 YTHDF1interactor70.38115.832YTH (PF04146, IPR007275): YT521-B-like domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
206 YTHDF3interactor40.3336.688Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
YTH (PF04146, IPR007275): YT521-B-like domain
207 ZC3H15interactor30.6673.895zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Torus (PF16131, IPR032297): Torus domain
DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46
208 ZC3HC1interactor40.33311.171Rsm1 (PF08600, IPR013909): Rsm1-like
zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like

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