Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	208
The number (and %) of the onco-proteins	51 (24.52 %)
The number (and %) of the tumor suppressors	28 (13.46 %)
Total number of binary PPIs (saturation %)	1330 (6.18 %)
The number (and %) of affected PPIs	210 (15.79 %)
The number of possible different fusions	29
PPI diameter	3
PPI radius	2
The average degree of PPI	12.192
Assortativity coefficient	-0.1481
The network average Clustering coefficient	0.381
The number (and %) of a zero Clustering coefficients	17 (8.17 %)
The number (and %) of a zero Betweenness Centrality	19 (9.13 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: TSC22D1,FAF1	All fusions
Proteins found in more fusions	CUL1 (see 3 fusions); CUL3 (see 1 fusions); TNFAIP1 (see 1 fusions); PJA2 (see 1 fusions); TSC22D1 (see 5 fusions); IKBKB (see 2 fusions); NUDT21 (see 2 fusions); UBC (see 1 fusions); TP53 (see 3 fusions); UGP2 (see 1 fusions); ILK (see 1 fusions); G3BP1 (see 1 fusions); VCP (see 4 fusions); PUF60 (see 2 fusions); BMPR1A (see 1 fusions); NCOA5 (see 1 fusions); PLOD2 (see 1 fusions); A2M (see 2 fusions); FAF1 (see 2 fusions); CD2AP (see 1 fusions); SNRNP200 (see 3 fusions); CD40 (see 2 fusions); SF1 (see 1 fusions); CHD3 (see 1 fusions); USP11 (see 4 fusions); UROD (see 1 fusions); TNNT1 (see 1 fusions); TSC22D1/FAF1 (see 1 fusions);

List of the fusions

PPI for parental proteins: TSC22D1,FAF1

All fusions

Proteins found in more fusions

CUL1 (see 3 fusions); CUL3 (see 1 fusions); TNFAIP1 (see 1 fusions); PJA2 (see 1 fusions); TSC22D1 (see 5 fusions); IKBKB (see 2 fusions); NUDT21 (see 2 fusions); UBC (see 1 fusions); TP53 (see 3 fusions); UGP2 (see 1 fusions); ILK (see 1 fusions); G3BP1 (see 1 fusions); VCP (see 4 fusions); PUF60 (see 2 fusions); BMPR1A (see 1 fusions); NCOA5 (see 1 fusions); PLOD2 (see 1 fusions); A2M (see 2 fusions); FAF1 (see 2 fusions); CD2AP (see 1 fusions); SNRNP200 (see 3 fusions); CD40 (see 2 fusions); SF1 (see 1 fusions); CHD3 (see 1 fusions); USP11 (see 4 fusions); UROD (see 1 fusions); TNNT1 (see 1 fusions); TSC22D1/FAF1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	TSC22D1	parental protein	87	0.027	10471.677	SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TSC22 (PF01166, IPR000580): TSC-22/dip/bun family ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
2	FAF1	parental protein	124	0.075	15103.514	UBX (PF00789, IPR001012, SM00166): UBX domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family AAA_11 (PF13086): AAA domain UBA_4 (PF14555): UBA-like domain
3	A2M	protein found in more fusions	9	0.036	66.298	A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor MP (PF01107, IPR028919): Viral movement protein (MP) SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA) Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
4	ACVR1	interactor	9	0.607	10.989	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
5	ACVR1B	oncoprotein	8	0.536	61.035	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
6	ACVRL1	interactor	5	0.200	23.817	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
7	ALB	interactor	4	0.167	27.867	Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
8	ALPP	interactor	7	0.619	8.792	Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase
9	AMFR	oncoprotein	17	0.475	52.456	CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
10	ANXA1	suppressor	10	0.083	103.741	Annexin (PF00191, IPR018502, SM00335): Annexin
11	ANXA7	suppressor	26	0.065	655.404	Annexin (PF00191, IPR018502, SM00335): Annexin
12	APLP1	interactor	10	0.400	32.906	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Ints3 (PF10189, IPR019333): Integrator complex subunit 3 APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
13	ASAH1	interactor	2	1.000	0	CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
14	ASCC2	interactor	3	1.000	0	CUE (PF02845, IPR003892, SM00546): CUE domain BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
15	ASNA1	interactor	11	0.545	63.484	ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase
16	ASPSCR1	oncoprotein	13	0.615	36.776	DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192) Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) UBX (PF00789, IPR001012, SM00166): UBX domain TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
17	BAG6	interactor	28	0.217	617.189	DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1
18	BMPR1A	suppressor	8	0.667	6.129	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
19	BMPR1B	interactor	5	0.833	0.909	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
20	BTBD9	interactor	4	1.000	0	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
21	BTRC	oncoprotein	21	0.337	167.909	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
22	C14orf1	interactor	6	0	41.490	Erg28 (PF03694, IPR005352): Erg28 like protein
23	CA10	interactor	2	1.000	0	Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
24	CACNA1A	interactor	6	0.133	23.427	Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
25	CARHSP1	interactor	2	0	2.508	DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
26	CARM1	oncoprotein	13	0.462	24.914	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
27	CARS	oncoprotein	10	0.800	4.798	tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain
28	CASP8	suppressor	11	0.378	99.943	DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
29	CBX3	interactor	8	0.333	31.513	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
30	CCDC90B	interactor	3	0	4.925	DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
31	CD2AP	protein found in more fusions	9	0.214	74.048	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
32	CD40	protein found in more fusions	4	0.667	0.637	Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
33	CDC5L	interactor	29	0.230	374.578	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
34	CDC73	suppressor	10	0.200	235.783	CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
35	CDK2	suppressor	28	0.236	406.447	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
36	CDKN1A	suppressor	43	0.114	1471.353	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
37	CDT1	oncoprotein	4	0.833	1.466	CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
38	CHD3	oncoprotein	17	0.133	248.354	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family
39	COPB2	interactor	8	0.333	25.449	Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
40	CORO2B	oncoprotein	1	0	0	DivIC (PF04977, IPR007060): Septum formation initiator DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat
41	CRMP1	interactor	14	0.244	149.293	Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
42	CSNK2B	interactor	21	0.147	472.528	CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
43	CTNNB1	oncoprotein	24	0.210	428.040	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
44	CUL1	suppressor	43	0.214	792.312	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
45	CUL2	suppressor	26	0.286	287.523	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
46	CUL3	protein found in more fusions	64	0.138	1926.207	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
47	DDAH2	interactor	9	0.028	78.817	Amidinotransf (PF02274, IPR003198): Amidinotransferase
48	DDOST	interactor	7	0.429	45.196	DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
49	DHDH	interactor	1	0	0	GFO_IDH_MocA (PF01408, IPR000683): Oxidoreductase family, NAD-binding Rossmann fold
50	DNAAF5	interactor	5	0.200	35.539	HEAT (PF02985, IPR000357): HEAT repeat Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
51	DNAJA1	interactor	14	0.549	28.035	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
52	DNAJB11	interactor	14	0.308	166.740	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
53	DNMT3B	suppressor	9	0.222	74.217	DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain
54	DYNC1H1	interactor	11	0.309	106.006	AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5
55	EED	suppressor	19	0.144	224.612	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
56	EMC1	interactor	3	0.333	2.995	DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620) PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat PQQ_2 (PF13360, IPR002372): PQQ-like domain
57	EPPK1	interactor	8	0.286	68.811	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
58	FADD	suppressor	5	0.700	3.670	Death (PF00531, IPR000488, SM00005): Death domain DED (PF01335, IPR001875, SM00031): Death effector domain Hpt (PF01627, IPR008207, SM00073): Hpt domain
59	FAM114A1	interactor	3	0.667	0.711	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
60	FAM20C	interactor	3	0	14.373	Fam20C (PF06702, IPR009581): Golgi casein kinase, C-terminal, Fam20 FAM198 (PF15051, IPR029207): FAM198 protein
61	FARSB	interactor	13	0.577	44.922	B3_4 (PF03483, IPR005146, SM00873): B3/4 domain B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
62	FAS	suppressor	10	0.194	72.200	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
63	FBN3	interactor	6	0.067	35.643	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain TB (PF00683, IPR017878): TB domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
64	FBXW11	interactor	16	0.286	143.080	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
65	G3BP1	protein found in more fusions	10	0.500	13.442	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
66	GART	interactor	17	0.574	32.959	AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain Formyl_trans_N (PF00551, IPR002376): Formyl transferase GARS_A (PF01071, IPR020561): Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C (PF02843, IPR020560): Phosphoribosylglycinamide synthetase, C domain GARS_N (PF02844, IPR020562): Phosphoribosylglycinamide synthetase, N domain
67	GCN1	interactor	6	0.333	33.823	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
68	GET4	interactor	11	0.727	12.063	DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410) Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
69	GNB2	interactor	9	0.361	33.800	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
70	GNB5	interactor	4	0.167	6.206	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
71	GSTK1	interactor	8	0.238	35.422	DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain
72	HIF1A	suppressor	13	0.487	25.094	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
73	HIRIP3	interactor	17	0.507	40.518	CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ
74	HIST1H4A	interactor	17	0.434	62.404	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
75	HMGXB4	oncoprotein	4	0	43.339	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4171 (PF13775, IPR025228): Domain of unknown function (DUF4171) RMP (PF14996, IPR029239): Retinal Maintenance
76	HNRNPM	interactor	19	0.298	179.677	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
77	HSD17B10	interactor	8	0.393	25.301	adh_short (PF00106, IPR002198): short chain dehydrogenase
78	HSPA2	interactor	7	0.524	8.960	HSP70 (PF00012, IPR013126): Hsp70 protein
79	HSPA4	interactor	29	0.232	456.657	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
80	HSPA8	oncoprotein	27	0.333	235.777	HSP70 (PF00012, IPR013126): Hsp70 protein
81	HSPH1	oncoprotein	24	0.377	128.862	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
82	IARS	interactor	10	0.333	79.062	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
83	IGF2	oncoprotein	2	1.000	0	IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family
84	IKBKAP	interactor	12	0.364	62.414	IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
85	IKBKB	protein found in more fusions	15	0.264	171.802	FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
86	ILK	suppressor	16	0.305	102.838	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
87	IPO5	interactor	6	0.667	10.004	HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat AAA_30 (PF13604): AAA domain HEAT_2 (PF13646): HEAT repeats PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
88	ITGB1BP1	interactor	1	0	0	ICAP-1_inte_bdg (PF10480, IPR019517): Beta-1 integrin binding protein
89	KBTBD7	interactor	5	0.600	17.856	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_2 (PF07646, IPR011498): Kelch motif Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif
90	KCTD10	interactor	7	0.857	2.807	BTB_2 (PF02214, IPR003131): BTB/POZ domain
91	KCTD13	interactor	6	1.000	0	BTB_2 (PF02214, IPR003131): BTB/POZ domain
92	KLHL22	interactor	5	0.900	0.467	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif
93	KMT2B	oncoprotein	7	0.048	34.131	FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus GRP (PF07172, IPR010800): Glycine rich protein family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
94	KMT2C	suppressor	2	0	9.008	AT_hook (PF02178, IPR017956, SM00384): AT hook motif FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus SLC12 (PF03522, IPR018491): Solute carrier family 12 MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box zf-HC5HC2H (PF13771): PHD-like zinc-binding domain zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
95	LARP7	interactor	5	0.200	38.834	Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif
96	LRIF1	interactor	17	0.183	227.328	LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
97	MAGIX	interactor	1	0	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
98	MAP3K12	interactor	2	1.000	0	APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
99	MCM3AP	interactor	3	0	20.238	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
100	MIOS	interactor	4	0.667	7.775	zinc_ribbon_16 (PF17034, IPR031488): Zinc-ribbon like family
101	MMAB	interactor	1	0	0	Cob_adeno_trans (PF01923, IPR016030): Cobalamin adenosyltransferase
102	MTR	interactor	4	0.333	12.638	B12-binding (PF02310, IPR006158): B12 binding domain B12-binding_2 (PF02607, IPR003759, SM01018): B12 binding domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase Met_synt_B12 (PF02965, IPR004223): Vitamin B12 dependent methionine synthase, activation domain Pterin_bind (PF00809, IPR000489): Pterin binding enzyme S-methyl_trans (PF02574, IPR003726): Homocysteine S-methyltransferase DUF2760 (PF10816, IPR021212): Domain of unknown function (DUF2760)
103	MYCBP2	interactor	4	1.000	0	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Filamin (PF00630, IPR017868): Filamin/ABP280 repeat Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHR (PF08005, IPR012983): PHR domain RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat SH3_3 (PF08239, IPR003646): Bacterial SH3 domain XPA_N (PF01286, IPR022652): XPA protein N-terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
104	NCOA5	suppressor	4	0.667	1.077	Macoilin (PF09726, IPR019130): Transmembrane protein
105	NDUFA9	interactor	3	0.333	15.599	Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
106	NGLY1	interactor	5	0.700	1.700	PUB (PF09409, IPR018997): PUB domain Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
107	NLRP12	interactor	3	1.000	0	NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
108	NLRP2	oncoprotein	2	1.000	0	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) AAA_16 (PF13191): AAA ATPase domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat
109	NLRP3	oncoprotein	2	1.000	0	NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
110	NLRP7	interactor	1	0	0	NACHT (PF05729): NACHT domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
111	NPLOC4	interactor	16	0.575	90.033	NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
112	NR1H2	oncoprotein	9	0.167	152.006	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
113	NR4A1	suppressor	7	0.333	50.774	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
114	NRBP1	suppressor	8	0.286	47.149	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
115	NSFL1C	interactor	18	0.536	55.669	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain
116	NTRK1	oncoprotein	85	0.103	4313.195	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
117	NUDT21	protein found in more fusions	15	0.209	176.764	NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
118	NUP50	interactor	6	0.400	18.813	NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
119	NUP93	oncoprotein	7	0.381	26.822	Nic96 (PF04097, IPR007231): Nup93/Nic96
120	NUP98	suppressor	7	0.333	20.773	Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head
121	OTUB1	interactor	24	0.207	528.239	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
122	PDHB	interactor	9	0.194	60.762	Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
123	PJA2	protein found in more fusions	7	0.667	6.656	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
124	PLOD2	protein found in more fusions	16	0.552	20.761	2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1 Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
125	PPM1G	interactor	13	0.513	52.061	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PP2C (PF00481, IPR001932): Protein phosphatase 2C DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
126	PPP2R5C	suppressor	4	0.333	3.440	B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) DUF1616 (PF07760, IPR011674): Protein of unknown function (DUF1616)
127	PRKCI	interactor	3	0.333	18.834	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
128	PRMT3	interactor	13	0.564	27.344	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
129	PTN	oncoprotein	8	0.143	40.208	PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
130	PUF60	protein found in more fusions	17	0.308	140.352	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
131	QARS	interactor	10	0.356	42.778	tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
132	RAD23A	oncoprotein	10	0.500	32.500	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
133	RAE1	interactor	15	0.276	112.236	Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
134	RANBP3	oncoprotein	17	0.537	123.779	Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
135	RAP1A	suppressor	7	0.381	22.419	Ras (PF00071, IPR001806, SM00173): Ras family
136	RAP1B	oncoprotein	11	0.055	126.653	Ras (PF00071, IPR001806, SM00173): Ras family
137	RCC1	interactor	18	0.072	313.018	RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
138	RELA	oncoprotein	18	0.324	109.676	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
139	RGS1	oncoprotein	2	1.000	0	RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
140	RPA3	interactor	15	0.286	145.780	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
141	RPL24	interactor	19	0.368	96.643	MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
142	RPL5	suppressor	14	0.333	83.245	Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
143	RPN2	interactor	12	0.364	115.301	Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
144	SAMHD1	interactor	15	0.615	18.938	HD (PF01966, IPR006674): HD domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
145	SEC23A	interactor	19	0.491	54.741	Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
146	SET	oncoprotein	14	0.538	53.069	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
147	SETDB1	interactor	12	0.333	110.438	MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
148	SF1	protein found in more fusions	17	0.567	50.906	UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
149	SFXN1	interactor	2	0	1.050	Mtc (PF03820, IPR004686): Tricarboxylate carrier
150	SIRT6	suppressor	11	0.164	58.310	SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
151	SKIL	suppressor	5	0	34.729	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
152	SKP1	oncoprotein	15	0.467	80.971	Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
153	SLC25A22	interactor	5	0.300	22.677	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
154	SMAD6	interactor	9	0.417	54.847	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
155	SMAD7	interactor	11	0.418	87.789	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
156	SNRNP200	protein found in more fusions	11	0.267	55.569	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
157	SP110	oncoprotein	4	0.167	6.132	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
158	SPACA9	interactor	1	0	0	DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
159	SPRED1	interactor	4	0	13.713	SMC_ScpA (PF02616, IPR003768): Segregation and condensation protein ScpA Sprouty (PF05210, IPR007875): Sprouty protein (Spry) WH1 (PF00568, IPR000697, SM00461): WH1 domain
160	SRPRB	interactor	7	0.381	37.065	MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
161	SWAP70	oncoprotein	9	0.500	21.493	DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) GrpE (PF01025, IPR000740): GrpE PH (PF00169, IPR001849, SM00233): PH domain CotJB (PF12652, IPR024207): CotJB protein EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
162	TAF1D	interactor	9	0.056	173.067	TAF1D (PF15333, IPR027976): TATA box-binding protein-associated factor 1D
163	TAF5L	interactor	4	0.500	3.354	TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
164	TCEAL1	interactor	4	0.500	1.338	BEX (PF04538, IPR021156): Brain expressed X-linked like family
165	TGFBR1	oncoprotein	9	0.278	79.792	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
166	TGFBR2	suppressor	7	0.571	16.370	ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
167	TK1	oncoprotein	26	0.083	785.315	TK (PF00265, IPR001267, SM00203): Thymidine kinase
168	TLE1	interactor	11	0.067	66.658	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
169	TLN1	interactor	7	0.476	23.846	DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
170	TNFAIP1	oncoprotein	8	0.714	9.161	BTB_2 (PF02214, IPR003131): BTB/POZ domain
171	TNNT1	protein found in more fusions	7	0.133	61.139	Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
172	TP53	suppressor	44	0.128	1266.282	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
173	TROVE2	interactor	18	0.536	44.359	TROVE (PF05731, IPR008858): TROVE domain DUF2201 (PF09967, IPR018698): VWA-like domain (DUF2201)
174	TSC22D4	interactor	6	0.333	34.212	AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
175	TTI1	interactor	5	0.500	8.328	Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal
176	UBC	protein found in more fusions	45	0.224	829.618	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
177	UBE2D1	interactor	25	0.159	431.412	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
178	UBL4A	interactor	22	0.312	137.257	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
179	UBR1	interactor	9	0.694	7.721	ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
180	UBR2	interactor	6	0.467	14.735	ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
181	UBR4	interactor	11	0.473	32.039	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family
182	UBXN1	interactor	30	0.293	239.655	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain
183	UBXN2B	interactor	6	0.600	4.323	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain
184	UBXN6	interactor	8	0.857	2.846	PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain
185	UBXN7	interactor	30	0.313	245.661	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
186	UFD1L	interactor	17	0.493	101.360	UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
187	UGP2	protein found in more fusions	19	0.412	78.922	UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
188	UNC119	interactor	7	0.048	34.131	GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
189	UNK	interactor	16	0.125	227.938	MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain
190	UROD	protein found in more fusions	5	0.167	46.699	URO-D (PF01208, IPR000257): Uroporphyrinogen decarboxylase (URO-D)
191	USP11	protein found in more fusions	18	0.294	290.406	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
192	VAPA	interactor	9	0.472	38.810	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
193	VAPB	interactor	11	0.655	12.768	ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
194	VCP	protein found in more fusions	45	0.241	1041.315	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
195	VCPIP1	interactor	14	0.626	57.068	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SDP_N (PF12278, IPR022063): Sex determination protein N terminal
196	VIM	suppressor	26	0.223	433.934	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
197	WDR24	interactor	4	0.833	0.500	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
198	WDR26	interactor	5	0.800	1.393	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
199	WDR59	interactor	4	0.667	7.775	RWD (PF05773, IPR006575, SM00591): RWD domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DZR (PF12773, IPR025874): Double zinc ribbon ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
200	WDR73	interactor	4	0.167	6.132	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
201	WDYHV1	interactor	3	0.333	16.998	Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase
202	WIZ	interactor	6	0.133	24.383	AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog) C1_2 (PF03107, IPR004146): C1 domain Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST zf-C2H2_4 (PF13894): C2H2-type zinc finger
203	WNK1	interactor	4	0.333	5.364	SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pkinase (PF00069, IPR000719): Protein kinase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
204	XPO7	interactor	17	0.596	29.030	IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
205	YTHDF1	interactor	7	0.381	15.832	YTH (PF04146, IPR007275): YT521-B-like domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
206	YTHDF3	interactor	4	0.333	6.688	Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit YTH (PF04146, IPR007275): YT521-B-like domain
207	ZC3H15	interactor	3	0.667	3.895	zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus (PF16131, IPR032297): Torus domain DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46
208	ZC3HC1	interactor	4	0.333	11.171	Rsm1 (PF08600, IPR013909): Rsm1-like zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like

B a c k t o T o p ⇑

Fusion ID: Protein names:	FAF1 TSC22D1
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