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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins F13A1 (from a repository: Thu Nov 10 14:59:26 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins6 (54.55 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)20 (36.36 %)
The number (and %) of affected PPIs11 (55.00 %)
The number of possible different fusions5
PPI diameter2
PPI radius1
The average degree of PPI2.545
Assortativity coefficient-0.3634
The network average Clustering coefficient0.387
The number (and %) of a zero Clustering coefficients5 (45.45 %)
The number (and %) of a zero Betweenness Centrality8 (72.73 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: F13A1 All fusions
: W26167;
Proteins found in more fusions PTK2 (see 2 fusions); NUDT21 (see 2 fusions); SH3GL2 (see 1 fusions); F13A1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 F13A1parental protein110.08978.000Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
2 ANXA7interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
3 CDKN1Aoncoprotein21.0000CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
4 F13Binteractor100Sushi_2 (PF09014, IPR015104): Beta-2-glycoprotein-1 fifth domain
V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
5 FGAinteractor31.0000Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Pentapeptide_2 (PF01469, IPR002989): Pentapeptide repeats (8 copies)
Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
Fibrinogen_aC (PF12160, IPR021996): Fibrinogen alpha C domain
6 FN1oncoprotein40.5003.000fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
7 NUDT21protein found in more fusions31.0000NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
8 PTK2protein found in more fusions200FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
9 SH3GL2oncoprotein200BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
10 TK1oncoprotein40.6671.000TK (PF00265, IPR001267, SM00203): Thymidine kinase
11 UFD1Linteractor100UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1

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