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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins EZH2 (from a repository: Thu Nov 24 14:33:45 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)275
The number (and %) of the onco-proteins78 (28.36 %)
The number (and %) of the tumor suppressors41 (14.91 %)
Total number of binary PPIs (saturation %)2048 (5.44 %)
The number (and %) of affected PPIs275 (13.43 %)
The number of possible different fusions48
PPI diameter2
PPI radius1
The average degree of PPI14.233
Assortativity coefficient-0.2557
The network average Clustering coefficient0.503
The number (and %) of a zero Clustering coefficients14 (5.09 %)
The number (and %) of a zero Betweenness Centrality38 (13.82 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: EZH2 All fusions
Proteins found in more fusions KDM2B (see 1 fusions); U2AF2 (see 2 fusions); CUL1 (see 3 fusions); COPB1 (see 2 fusions); WWP1 (see 1 fusions); EWSR1 (see 2 fusions); DDX5 (see 1 fusions); SUZ12 (see 2 fusions); ZMYND11 (see 1 fusions); VCP (see 4 fusions); PRMT5 (see 2 fusions); JAK2 (see 3 fusions); HUWE1 (see 2 fusions); NCOA1 (see 2 fusions); YY1 (see 2 fusions); SNRNP200 (see 3 fusions); MYOD1 (see 1 fusions); KDM1A (see 2 fusions); HSPB1 (see 3 fusions); EZH2 (see 1 fusions); ZAK (see 2 fusions); PML (see 4 fusions); SUV39H1 (see 1 fusions); CHD4 (see 6 fusions); NCL (see 3 fusions); TRIM25 (see 2 fusions); CDK6 (see 1 fusions); KAT2B (see 1 fusions); IMMT (see 4 fusions); ACTG1 (see 4 fusions); RARA (see 4 fusions); NUDT21 (see 2 fusions); SS18 (see 1 fusions); ITSN2 (see 1 fusions); FUS/PKM (see 1 fusions); RARA/PML (see 21 fusions); CRY2 (see 3 fusions); LUC7L2 (see 2 fusions); TRIM28 (see 1 fusions); ACTN1 (see 3 fusions); EZH2/ATP2A2 (see 1 fusions); KHDRBS1 (see 1 fusions); RACK1 (see 3 fusions); EHMT1 (see 3 fusions); SRSF1 (see 1 fusions); MAP3K7 (see 7 fusions); SYNE1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 EZH2parental protein2750.04549579.416CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
2 ACTG1protein found in more fusions120.41815.479Actin (PF00022, IPR004000, SM00268): Actin
3 ACTN1protein found in more fusions80.6672.884CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
4 ADARinteractor90.5835.471dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain
A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain
5 AEBP2interactor110.6557.040Bindin (PF02084, IPR000775): Bindin
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
DUF4764 (PF15961, IPR031885): Domain of unknown function (DUF4764)
6 AKAP8interactor80.4294.836AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
7 AKT1oncoprotein200.35751.598PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
8 ANKFY1interactor100Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
9 ANXA4interactor21.0000Annexin (PF00191, IPR018502, SM00335): Annexin
10 API5interactor50.6000.770API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
11 ARoncoprotein230.32079.204Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
12 ARG1suppressor31.0000Arginase (PF00491, IPR006035): Arginase family
13 ASPSCR1oncoprotein41.0000DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
14 ASXL1suppressor30.6670.222HARE-HTH (PF05066, IPR007759): HB1, ASXL, restriction endonuclease HTH domain
ASXH (PF13919, IPR028020): Asx homology domain
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
15 ATP1A1interactor70.3817.297Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
Tetraspannin (PF00335, IPR018499): Tetraspanin family
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
16 ATP1B1interactor50.5002.987Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
17 ATP2A2protein found in more fusions60.5333.200Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
18 ATP5Binteractor110.41813.577AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
19 ATP5C1interactor90.38916.965ATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
20 ATRXoncoprotein60.5334.356DDHD (PF02862, IPR004177, SM01127): DDHD domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Pap_E4 (PF02711, IPR003861): E4 protein
PHD (PF00628, IPR019787, SM00249): PHD-finger
Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Zip (PF02535, IPR003689): ZIP Zinc transporter
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2992 (PF11208, IPR016787): Protein of unknown function (DUF2992)
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
FAM176 (PF14851): FAM176 family
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
21 BRCA1suppressor410.233329.718BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
22 BTRConcoprotein270.249152.176WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
23 C10orf12interactor80.5715.456DUF4553 (PF15090, IPR028104): Domain of unknown function (DUF4553)
24 C17orf96interactor21.0000DUF4584 (PF15223, IPR027971): Domain of unknown function (DUF4584)
25 C7orf25interactor21.0000DUF1308 (PF07000, IPR010733): Protein of unknown function (DUF1308)
DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
26 CALML3interactor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
27 CCDC85Binteractor30.6671.000CCDC85 (PF10226, IPR019359): CCDC85 family
28 CCDC93interactor30.6671.000Cir_Bir_Yir (PF06022, IPR006477): Plasmodium variant antigen protein Cir/Yir/Bir
Iron_permease (PF04120, IPR007251): Low affinity iron permease
Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34
KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
29 CDCA7Linteractor60.4003.222zf-4CXXC_R1 (PF10497, IPR018866): Zinc-finger domain of monoamine-oxidase A repressor R1
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
30 CDK1oncoprotein170.25849.479Pkinase (PF00069, IPR000719): Protein kinase domain
31 CDK2suppressor580.128814.179Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
32 CDK6suppressor150.36327.012Pkinase (PF00069, IPR000719): Protein kinase domain
33 CDKN2B-AS1interactor100NA
34 CDKN2Csuppressor30.6670.500Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
35 CDYLinteractor90.7781.957Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
36 CENPVinteractor31.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
GFA (PF04828, IPR006913): Glutathione-dependent formaldehyde-activating enzyme
37 CEP192interactor40.6671.667Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
TMEM131_like (PF12371, IPR022113): Transmembrane protein 131-like
MYCBPAP (PF14646, IPR032707): MYCBP-associated protein family
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
38 CEP63interactor50.5004.000DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa
39 CHCHD3interactor40.6672.000DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
eIF3g (PF12353, IPR024675): Eukaryotic translation initiation factor 3 subunit G
40 CHD4oncoprotein170.6588.751CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
41 CITinteractor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CNH (PF00780, IPR001180, SM00036): CNH domain
Dec-1 (PF04624, IPR006718): Dec-1 repeat
DivIC (PF04977, IPR007060): Septum formation initiator
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
42 CNBPoncoprotein80.4646.272zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-ribbon_3 (PF13248): zinc-ribbon domain
43 COPB1protein found in more fusions80.3339.037Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
44 CPSF1interactor40.6671.333CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
45 CPSF2interactor50.5004.000RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
46 CPSF6interactor140.39635.684RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
47 CPSF7interactor80.5717.824CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
48 CRY2protein found in more fusions220.25278.622DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
49 CSNK2Binteractor160.31446.248CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
50 CTNNB1oncoprotein270.288115.045Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
51 CUL1suppressor650.180888.874Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
52 DAZAP1interactor80.7141.600RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
53 DBN1oncoprotein120.42418.452Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
54 DDB2suppressor90.4299.568WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
55 DDX3Xsuppressor150.45722.378DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
56 DDX5oncoprotein340.324156.484DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
57 DEC1suppressor60.6001.817DEC1 (PF15859, IPR031718): Deleted in esophageal cancer 1 family
58 DHX30interactor70.7621.042Bombolitin (PF08096, IPR012534): Bombolitin family
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59 DHX36interactor30.6671.000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
60 DHX9oncoprotein340.360136.726DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
61 DNAAF5interactor21.0000HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
62 DNAJB11interactor70.4298.377DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
63 DNAJC21interactor21.0000Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF788 (PF05620, IPR008506): Protein of unknown function (DUF788)
Sec62 (PF03839, IPR004728): Translocation protein Sec62
DUF2756 (PF10956, IPR020158): Protein of unknown function (DUF2756)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
DBINO (PF13892, IPR020838): DNA-binding domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
64 DNMT1suppressor250.42861.038BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
65 DNMT3Asuppressor130.6159.689DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
66 DNMT3Bsuppressor170.58114.999DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
67 DSC3suppressor21.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
68 DYNLT3interactor200Tctex-1 (PF03645, IPR005334): Tctex-1 family
69 E2F6oncoprotein70.5714.918BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
70 EEDsuppressor1000.1152708.872WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
71 EFTUD2interactor190.57517.624EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
72 EHMT1oncoprotein120.6735.064Pre-SET (PF05033, IPR007728): Pre-SET motif
Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family
SET (PF00856, IPR001214, SM00317): SET domain
XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
Zip (PF02535, IPR003689): ZIP Zinc transporter
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551)
73 EHMT2interactor200.39241.409CDC45 (PF02724, IPR003874): CDC45-like protein
Pre-SET (PF05033, IPR007728): Pre-SET motif
Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family
SET (PF00856, IPR001214, SM00317): SET domain
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
74 ELAVL1oncoprotein660.1151307.808RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
75 EPC1interactor31.0000E_Pc_C (PF06752, IPR009607): Enhancer of Polycomb C-terminus
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
76 EPC2interactor21.0000E_Pc_C (PF06752, IPR009607): Enhancer of Polycomb C-terminus
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
77 EPRSinteractor140.44018.452GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal
tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
78 ERHinteractor100.35612.955ER (PF01133, IPR000781): Enhancer of rudimentary
79 ESR1suppressor770.1471400.385Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
80 EWSR1oncoprotein410.223335.144RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
81 EZH1suppressor90.5716.408TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
82 FABP5interactor40.6670.600Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
83 FAM120Ainteractor30.6670.167TPR_15 (PF13429): Tetratricopeptide repeat
84 FAM208Ainteractor31.0000DUF3715 (PF12509, IPR022188): Protein of unknown function (DUF3715)
85 FAT1suppressor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
DUF2808 (PF10989, IPR021256): Protein of unknown function (DUF2808)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
Cadherin_3 (PF16184): Cadherin-like
86 FBLinteractor150.37132.300Fibrillarin (PF01269, IPR000692): Fibrillarin
87 FBXL18interactor40.6671.167LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
88 FBXW11interactor360.232230.627WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
89 FIP1L1oncoprotein80.42911.919Fip1 (PF05182, IPR007854): Fip1 motif
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
Auts2 (PF15336): Autism susceptibility gene 2 protein
90 FLGinteractor100Filaggrin (PF03516, IPR003303): Filaggrin
S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
Hid1 (PF12722): High-temperature-induced dauer-formation protein
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266)
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
91 FNBP1Linteractor100FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
DEDD_Tnp_IS110 (PF01548, IPR002525): Transposase
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
GTP-bdg_M (PF16360, IPR032305): GTP-binding GTPase Middle Region
92 FUSsuppressor320.256171.997Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
93 GADD45Gsuppressor60.3334.498Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
94 GATA4suppressor50.9000.400Apidaecin (PF00807, IPR004828): Apidaecin
GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal
DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387)
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
95 GEMIN7interactor50.7003.000Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
96 GTF3C1interactor80.4294.347B-block_TFIIIC (PF04182, IPR007309): B-block binding subunit of TFIIIC
97 H2AFYinteractor110.6009.982DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
98 HDAC1suppressor490.252420.261FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
99 HDAC2suppressor420.288246.257Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
100 HDAC3suppressor250.25481.421Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
101 HIC1suppressor80.8101.134BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
102 HIST1H1Ainteractor230.186132.028Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
103 HIST1H2ABinteractor90.5008.355Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
104 HIST1H2AEinteractor40.5000.211Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
105 HIST1H3Ainteractor360.227288.537Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
106 HIST3H3interactor300.280162.360Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
107 HIST4H4interactor100.5787.815CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
108 HNRNPABinteractor110.4919.003CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
GRP (PF07172, IPR010800): Glycine rich protein family
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
109 HOTAIRinteractor30.6670.200NA
110 HSPA1Ainteractor160.35036.306HSP70 (PF00012, IPR013126): Hsp70 protein
111 HSPA1Binteractor60.5334.567HSP70 (PF00012, IPR013126): Hsp70 protein
112 HSPB1oncoprotein230.216129.589HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
113 HUWE1oncoprotein420.173343.877BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
114 HYOU1interactor40.5001.133HSP70 (PF00012, IPR013126): Hsp70 protein
AbiEi_3_N (PF17194): Transcriptional regulator, AbiEi antitoxin N-terminal domain
115 IGLL5interactor21.0000C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
116 ILF2interactor290.367110.606DZF (PF07528, IPR006561, SM00572): DZF domain
117 ILF3oncoprotein270.40583.715dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
118 IMMTprotein found in more fusions90.32114.248Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
119 ITSN2protein found in more fusions70.3337.167C2 (PF00168, IPR000008, SM00239): C2 domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
120 JAK2oncoprotein60.5002.700FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
121 JARID2interactor140.52719.725ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
TLP-20 (PF06088, IPR009092): Nucleopolyhedrovirus telokin-like protein-20 (TLP20)
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
Macoilin (PF09726, IPR019130): Transmembrane protein
122 KAT2Bprotein found in more fusions210.27969.693Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
123 KAT7interactor60.4005.483MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
zf-C2HC (PF01530, IPR002515, SM00343): Zinc finger, C2HC type
zf-met (PF12874): Zinc-finger of C2H2 type
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
124 KDM1Aprotein found in more fusions250.341109.581Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
125 KDM2Boncoprotein70.5334.098zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
Cupin_8 (PF13621): Cupin-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
MRI (PF15325, IPR028278): Modulator of retrovirus infection
PHD_4 (PF16866, IPR019787): PHD-finger
126 KDM5Asuppressor90.8331.228ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
FRG1 (PF06229, IPR010414): FRG1-like domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLU-1 (PF08429, IPR013637): PLU-1-like protein
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
127 KHDRBS1protein found in more fusions150.42930.536KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
128 KIF5Binteractor90.30619.273ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
129 KLC1interactor70.4299.967Gly_radical (PF01228, IPR001150): Glycine radical
SOGA (PF11365, IPR027881): Protein SOGA
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
130 KLC2interactor60.5337.000TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
131 KLC4interactor41.0000Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
LUD_dom (PF02589): LUD domain
132 KLHDC2interactor100Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
DUF4370 (PF14290, IPR025397): Domain of unknown function (DUF4370)
133 KLHL12interactor40.6670.667BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
134 KMT5Ainteractor70.9050.733ATP-synt_Eps (PF04627, IPR006721): Mitochondrial ATP synthase epsilon chain
ERp29 (PF07749, IPR011679): Endoplasmic reticulum protein ERp29, C-terminal domain
SET (PF00856, IPR001214, SM00317): SET domain
135 LARP1interactor100.55610.635La (PF05383, IPR006630, SM00715): La domain
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
136 LGALS7suppressor40.8330.050Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
137 LIMA1suppressor60.8000.850LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
138 LOXL2oncoprotein51.0000Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
139 LRPPRCinteractor60.5332.586DED (PF01335, IPR001875, SM00031): Death effector domain
MA3 (PF02847, IPR003891, SM00544): MA3 domain
PPR (PF01535, IPR002885): PPR repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
TPR_19 (PF14559): Tetratricopeptide repeat
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
140 LRRC40interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
141 LUC7L2protein found in more fusions260.38391.306LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
142 MAGOHinteractor330.288142.114Mago_nashi (PF02792, IPR004023): Mago nashi protein
143 MAP3K7oncoprotein60.5001.919Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
144 MAPK8IP2interactor60.8000.444BUD22 (PF09073, IPR015158): BUD22
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
145 MAPKAPK3interactor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
146 MDM2oncoprotein380.290217.401Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
147 MED1interactor100.3619.003Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
148 MKI67interactor70.4766.228FHA (PF00498, IPR000253, SM00240): FHA domain
K167R (PF08065, IPR012568): K167R (NUC007) repeat
PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding
AROS (PF15684, IPR023262): Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1
149 MKRN2interactor40.6670.667RecR (PF02132, IPR023628): RecR protein
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
zf-RING_11 (PF17123, IPR001841): RING-like zinc finger
150 MRPL2interactor21.0000Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
151 MTF2interactor80.7141.874PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
152 MYLPFinteractor100EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
153 MYOD1oncoprotein130.40918.546Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Mfp-3 (PF04202, IPR007328): Foot protein 3
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
154 NCLprotein found in more fusions210.40543.259DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
155 NCOA1oncoprotein100.41710.248DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
156 NINLinteractor80.28615.233PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
157 NOP14interactor30.6670.250Nop14 (PF04147, IPR007276): Nop14-like family
158 NOP2interactor110.6009.444BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
159 NPLOC4interactor90.52810.941NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
160 NUDT21protein found in more fusions180.29444.913NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
161 NUMA1oncoprotein90.6672.279Colicin (PF01024, IPR000293): Colicin pore forming domain
Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
162 OIP5interactor40.6671.000Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
163 P4HBinteractor100.6673.850Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
164 PABPC4interactor140.47314.696ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
165 PCGF1interactor100.5289.061zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
166 PDCD6IPinteractor80.3818.650BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
167 PDS5Ainteractor30.6670.286HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
168 PFDN1interactor30.6670.667Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
169 PHB2interactor200.35860.889DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
170 PHF1interactor120.6068.728PHD (PF00628, IPR019787, SM00249): PHD-finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
171 PHF19interactor100.7782.157PHD (PF00628, IPR019787, SM00249): PHD-finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
172 PHF5Ainteractor80.7142.409PHF5 (PF03660, IPR005345): PHF5-like protein
173 PHGDHinteractor160.39224.7682-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
174 PIN4interactor21.0000Rotamase_3 (PF13616): PPIC-type PPIASE domain
175 PJA1interactor60.8001.167zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
176 PKMoncoprotein190.37448.992PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
177 PLEConcoprotein80.6432.667CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
178 PMLsuppressor270.286110.811zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
179 POLA2interactor30.6670.500DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
180 POTEEinteractor21.0000Actin (PF00022, IPR004000, SM00268): Actin
DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
CCDC144C (PF14915): CCDC144C protein coiled-coil region
181 POU5F1oncoprotein250.181148.056Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
182 PPARGsuppressor130.42414.722zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
183 PPP1R8interactor60.8670.619FHA (PF00498, IPR000253, SM00240): FHA domain
184 PRDM14interactor40.6671.000Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
SET (PF00856, IPR001214, SM00317): SET domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
185 PRMT5protein found in more fusions170.30044.074PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
186 PSMB6interactor70.4767.335DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502)
Proteasome (PF00227, IPR001353): Proteasome subunit
187 RACK1suppressor180.29459.063WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188 RALYinteractor90.6674.604RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
189 RAP1GAPsuppressor31.0000GoLoco (PF02188, IPR003109, SM00390): GoLoco motif
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
190 RARAoncoprotein170.40027.886zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
191 RASA1oncoprotein40.5001.200C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
192 RBBP4oncoprotein350.313198.304eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
193 RBBP7suppressor230.47848.070WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
194 RBL2suppressor100.5335.203CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
195 RBM14suppressor140.58210.634RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
196 RBM39oncoprotein220.50241.258RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
197 RBX1oncoprotein180.23566.028zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
198 REEP4interactor100TB2_DP1_HVA22 (PF03134, IPR004345): TB2/DP1, HVA22 family
199 RELAoncoprotein320.249186.185DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
200 RELBoncoprotein70.4763.624RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper
RelB_transactiv (PF16181, IPR032400): RelB transactivation domain
201 RIN3interactor21.0000RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
SH2 (PF00017, IPR000980, SM00252): SH2 domain
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
202 RORAinteractor30.6670.500zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
203 RPL36interactor50.8000.667Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
204 RPN2interactor80.6432.014Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
205 RPS6KA5interactor70.2868.356Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
206 RUNX3suppressor70.6192.540Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
207 SAFB2suppressor60.6670.670LicD (PF04991, IPR007074): LicD family
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
208 SDCBPinteractor80.39310.831PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
209 SEPT2oncoprotein130.42324.210FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
210 SERPINB12interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
211 SF3B1oncoprotein330.362142.592Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
212 SF3B2interactor200.41657.945DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382)
PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
PSP (PF04046, IPR006568, SM00581): PSP
SAP (PF02037, IPR003034, SM00513): SAP domain
Usp (PF00582, IPR006016): Universal stress protein family
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
213 SF3B3interactor300.44175.770CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
214 SIRT1suppressor300.278144.951DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
215 SLC25A10interactor21.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
216 SMN1interactor260.213124.493SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
217 SMYD3oncoprotein40.6670.205SET (PF00856, IPR001214, SM00317): SET domain
218 SNAI1oncoprotein120.5768.104zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
219 SNRNP200protein found in more fusions250.48952.595DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
220 SNRNP70interactor250.39784.502RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
221 SNRPAinteractor100.7501.032RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
222 SNRPB2interactor90.5834.753DUF1027 (PF06265, IPR009370): Protein of unknown function (DUF1027)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
223 SNRPD1interactor280.45273.785API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
224 SNRPD2interactor200.55322.751LSM (PF01423, IPR001163): LSM domain
225 SNRPD3interactor220.45052.423LSM (PF01423, IPR001163): LSM domain
226 SNRPFinteractor90.5833.812LSM (PF01423, IPR001163): LSM domain
227 SNRPNinteractor60.7331.550LSM (PF01423, IPR001163): LSM domain
228 SONinteractor160.59212.058Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
229 SRSF1protein found in more fusions310.43481.049Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
230 SRSF10interactor140.47315.200RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
231 SRSF3oncoprotein240.48941.562DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
232 SRSF7interactor250.47054.049RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
233 SRSF9interactor160.60011.012RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
234 SS18oncoprotein90.7143.073SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
235 SSR1interactor70.5713.188TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
236 SSX2oncoprotein60.8000.786KRAB (PF01352, IPR001909, SM00349): KRAB box
237 SUV39H1protein found in more fusions270.308118.221Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
238 SUZ12suppressor1360.0985360.611DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
239 SYNE1oncoprotein40.6670.500Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
POX (PF07526, IPR006563, SM00574): Associated with HOX
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
THOC7 (PF05615, IPR008501): Tho complex subunit 7
TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
KASH (PF10541, IPR012315): Nuclear envelope localisation domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416)
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
240 TAF15oncoprotein80.5712.897API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Presenilin (PF01080, IPR001108): Presenilin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
241 TAF1Dinteractor30.6670.667TAF1D (PF15333, IPR027976): TATA box-binding protein-associated factor 1D
242 TDRD1interactor100TUDOR (PF00567, IPR002999, SM00333): Tudor domain
zf-MYND (PF01753, IPR002893): MYND finger
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
243 THRAP3oncoprotein160.45022.563API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
244 TK1oncoprotein80.2867.390TK (PF00265, IPR001267, SM00203): Thymidine kinase
245 TLE1interactor150.27541.530TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
246 TNFSF11interactor100TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
DUF2735 (PF10931, IPR021232): Protein of unknown function (DUF2735)
247 TPI1interactor80.5712.975TIM (PF00121, IPR000652): Triosephosphate isomerase
248 TRA2Ainteractor230.38364.216DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
249 TRIM25protein found in more fusions80.5246.000Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
250 TRIM28protein found in more fusions210.42132.288ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
251 TRIM37oncoprotein90.42913.082MATH (PF00917, IPR002083, SM00061): MATH domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
252 TUBA1Binteractor80.3937.133Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
253 TUBB4Binteractor90.41710.095Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
254 U2AF1oncoprotein210.46740.288DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
255 U2AF2protein found in more fusions580.255471.483RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
256 UBBinteractor50.7000.550ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
257 UFD1Linteractor90.6115.422UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
258 UHRF1interactor190.45830.333PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
259 UPF1interactor180.38637.501UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
260 USP7oncoprotein330.244203.952MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
261 VAV1oncoprotein50.6002.250PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
262 VCPprotein found in more fusions410.221353.302AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
263 WDR61interactor40.5001.352WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
264 WDR76interactor60.4675.452WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SPATIAL (PF15256): SPATIAL
265 WSB2interactor21.0000PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
SOCS_box (PF07525, IPR001496): SOCS box
266 WT1suppressor50.8000.600WT1 (PF02165, IPR000976): Wilm's tumour protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
CCAP (PF11105, IPR024276): Arthropod cardioacceleratory peptide 2a
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
267 WWP1oncoprotein70.4006.900C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
268 WWP2interactor110.37817.181WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
269 YBX1oncoprotein230.41552.317CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
270 YBX3interactor100.6442.514CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1)
271 YY1protein found in more fusions160.45723.606zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
272 ZAKprotein found in more fusions50.6671.167Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
273 ZC3HAV1interactor50.4002.937PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
WWE (PF02825, IPR004170, SM00678): WWE domain
274 ZMYND11suppressor120.32714.966DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002)
DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353)
PWWP (PF00855, IPR000313, SM00293): PWWP domain
zf-MYND (PF01753, IPR002893): MYND finger
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
275 ZNF638interactor60.5336.333RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus

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