1 |
ERRFI1 | parental protein | 50 | 0.115 | 1606.279 | GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 |
2 |
ACTA1 | interactor | 5 | 0.700 | 1.833 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ACTA2 | interactor | 5 | 0.600 | 3.200 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTB | oncoprotein | 10 | 0.611 | 6.350 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTBL2 | interactor | 3 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ACTC1 | interactor | 2 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
7 |
ACTG1 | protein found in more fusions | 10 | 0.556 | 10.683 | Actin (PF00022, IPR004000, SM00268): Actin |
8 |
ACTG2 | interactor | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
9 |
ALK | oncoprotein | 4 | 1.000 | 0 | MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
10 |
ANXA2 | interactor | 5 | 0.800 | 0.367 | Annexin (PF00191, IPR018502, SM00335): Annexin |
11 |
ATM | suppressor | 4 | 0.667 | 0.333 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
12 |
AURKA | oncoprotein | 7 | 0.667 | 1.752 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
13 |
AXL | oncoprotein | 4 | 0.667 | 0.917 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2627 (PF11118, IPR020138): Protein of unknown function (DUF2627) Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
14 |
BAG4 | interactor | 3 | 0.667 | 0.333 | BAG (PF02179, IPR003103, SM00264): BAG domain DMP12 (PF16779, IPR031891): DNA-mimic protein |
15 |
BCAR3 | oncoprotein | 2 | 1.000 | 0 | RasGEF (PF00617, IPR001895, SM00147): RasGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
16 |
CASP8 | suppressor | 2 | 0 | 0 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
17 |
CCT3 | interactor | 4 | 0.833 | 0.286 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
18 |
CDC42 | oncoprotein | 4 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
19 |
EGFR | oncoprotein | 18 | 0.426 | 46.436 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
20 |
ELAVL1 | oncoprotein | 12 | 0.327 | 28.583 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
21 |
ERBB2 | oncoprotein | 10 | 0.500 | 12.717 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
22 |
ESRRB | suppressor | 14 | 0.484 | 22.090 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
23 |
FGFR2 | oncoprotein | 2 | 0 | 0 | Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
24 |
FGFR4 | oncoprotein | 2 | 0 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain |
25 |
GFAP | protein found in more fusions | 6 | 0.900 | 0.167 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
26 |
GRB2 | oncoprotein | 24 | 0.320 | 112.140 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
27 |
HSPA1A | interactor | 9 | 0.583 | 7.352 | HSP70 (PF00012, IPR013126): Hsp70 protein |
28 |
HSPA8 | oncoprotein | 14 | 0.505 | 28.671 | HSP70 (PF00012, IPR013126): Hsp70 protein |
29 |
LTK | interactor | 1 | 0 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
30 |
MASP1 | interactor | 1 | 0 | 0 | CUB (PF00431, IPR000859, SM00042): CUB domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
31 |
PALB2 | suppressor | 2 | 0 | 0 | IncA (PF04156, IPR007285): IncA protein PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain |
32 |
PDGFRB | oncoprotein | 5 | 1.000 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain Ig_3 (PF13927): Immunoglobulin domain TonB_N (PF16031): TonB N-terminal region |
33 |
POTEE | interactor | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region |
34 |
POTEF | oncoprotein | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin Toxin_16 (PF07945, IPR012499): Janus-atracotoxin Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region |
35 |
POTEKP | interactor | 3 | 0.667 | 0.400 | NA |
36 |
PPM1D | oncoprotein | 1 | 0 | 0 | PP2C (PF00481, IPR001932): Protein phosphatase 2C |
37 |
RB1CC1 | suppressor | 1 | 0 | 0 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DHC (PF09626, IPR018588): Dihaem cytochrome c DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) ATG11 (PF10377, IPR019460): Autophagy-related protein 11 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Jag_N (PF14804, IPR032782): Jag N-terminus NPBW (PF15180, IPR013297): Neuropeptides B and W HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain |
38 |
RPS27A | interactor | 4 | 1.000 | 0 | DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049) |
39 |
SFN | suppressor | 7 | 0.667 | 3.167 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
40 |
SHC1 | oncoprotein | 20 | 0.351 | 66.410 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
41 |
SHC2 | interactor | 3 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
42 |
TUBA1A | oncoprotein | 8 | 0.750 | 2.205 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
43 |
TUBA1B | interactor | 8 | 0.679 | 2.986 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
44 |
TUBA1C | interactor | 9 | 0.583 | 7.167 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
45 |
TUBB | interactor | 17 | 0.529 | 26.679 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
46 |
UBASH3B | interactor | 15 | 0.484 | 23.652 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
47 |
XPO1 | interactor | 10 | 0.489 | 10.938 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
48 |
YWHAE | oncoprotein | 10 | 0.578 | 7.919 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
49 |
YWHAQ | interactor | 15 | 0.457 | 30.905 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
50 |
YWHAZ | protein found in more fusions | 10 | 0.611 | 9.083 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |